Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2021 年第 4 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2021/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 341
- 較 2021 年第 3 季 +20 家
- 持有股數
- 1.23 億
- 較 2021 年第 3 季 +170.8 萬 (+1.4%)
- 總市值
- $37.5 億
- 較 2021 年第 3 季 −$3.26 億 (−8.0%)
- 新進機構
- 59
- 另有 106 家加碼
- 清倉機構
- 39
- 另有 119 家減碼
另有 5 家機構在 2021 年第 3 季持有、還沒有申報 2021 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2021 年第 4 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2021 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 21,181,502 | $6.45 億 | 0.05% | +9,3480.0% | 加碼 |
| Price T Rowe Associates Inc | 12,490,280 | $3.80 億 | 0.03% | +752,959+6.4% | 加碼 |
| Vanguard Group Inc | 12,007,076 | $3.65 億 | 0.01% | +207,067+1.8% | 加碼 |
| Bellevue Group AG | 10,355,123 | $3.15 億 | 3.25% | +1,007,197+10.8% | 加碼 |
| BlackRock Inc. | 8,539,282 | $2.60 億 | 0.01% | +419,429+5.2% | 加碼 |
| ARK Investment Management LLC大師方舟投資 | 7,083,256 | $2.16 億 | 0.65% | −1,428,128−16.8% | 減碼 |
| Clearbridge Investments, LLC | 5,882,982 | $1.79 億 | 0.12% | −1,444,340−19.7% | 減碼 |
| State Street Corp | 3,906,375 | $1.19 億 | 0.01% | +385,061+10.9% | 加碼 |
| Geode Capital Management, LLC | 1,825,226 | $5,554 萬 | 0.01% | +52,459+3.0% | 加碼 |
| First Trust Advisors LP | 1,680,012 | $5,112 萬 | 0.05% | −5370.0% | 減碼 |
| Millennium Management LLC | 1,623,138 | $4,939 萬 | 0.05% | +1,340,284+473.8% | 加碼 |
| Thrivent Financial for Lutherans | 1,533,999 | $4,668 萬 | 0.09% | +146,235+10.5% | 加碼 |
| Jacobs Levy Equity Management, Inc | 1,407,388 | $4,283 萬 | 0.29% | +216,152+18.1% | 加碼 |
| Camber Capital Management LP | 1,390,000 | $4,230 萬 | 1.63% | −1,110,000−44.4% | 減碼 |
| JPMorgan Chase & Co | 1,268,652 | $3,861 萬 | 0.00% | −1,147,661−47.5% | 減碼 |
| Citadel Advisors LLC | 1,221,571 | $3,717 萬 | 0.04% | +171,714+16.4% | 加碼 |
| Swedbank AB | 1,117,339 | $3,412 萬 | 0.06% | 00.0% | 不變 |
| Charles Schwab Investment Management Inc | 1,093,439 | $3,327 萬 | 0.01% | +23,707+2.2% | 加碼 |
| Candriam Luxembourg S.C.A. | 936,635 | $2,850 萬 | 0.18% | +210,276+28.9% | 加碼 |
| Norges Bank | 831,219 | $2,529 萬 | 0.01% | −315,699−27.5% | 減碼 |
| Wells Fargo & Company | 810,966 | $2,468 萬 | 0.01% | −42,404−5.0% | 減碼 |
| TD Asset Management Inc | 743,164 | $2,261 萬 | 0.02% | +321,200+76.1% | 加碼 |
| Northern Trust Corp | 660,890 | $2,011 萬 | 0.00% | +5,469+0.8% | 加碼 |
| Privium Fund Management B.V. | 630,199 | $1,925 萬 | 3.83% | +630,199 | 新進 |
| Bank of America Corp | 612,835 | $1,865 萬 | 0.00% | −97,282−13.7% | 減碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 605,902 | $1,844 萬 | 0.01% | −79,758−11.6% | 減碼 |
| Bank of Nova Scotia | 601,883 | $1,832 萬 | 0.03% | +589,568+4,787.4% | 加碼 |
| Two Sigma Investments, LP | 594,885 | $1,810 萬 | 0.04% | +280,751+89.4% | 加碼 |
| Nikko Asset Management Americas, Inc. | 605,902 | $1,794 萬 | 0.09% | −69,399−10.3% | 減碼 |
| Goldman Sachs Group Inc | 589,298 | $1,793 萬 | 0.00% | −12,538−2.1% | 減碼 |
| Bank of New York Mellon Corp | 556,577 | $1,694 萬 | 0.00% | −3,989−0.7% | 減碼 |
| Pinnacle Associates Ltd | 541,044 | $1,646 萬 | 0.28% | −2,182−0.4% | 減碼 |
| Two Sigma Advisers, LP | 497,411 | $1,514 萬 | 0.04% | +65,200+15.1% | 加碼 |
| Royal Bank of Canada | 480,648 | $1,463 萬 | 0.00% | −8,913−1.8% | 減碼 |
| Morgan Stanley | 464,885 | $1,415 萬 | 0.00% | −33,051−6.6% | 減碼 |
| Woodline Partners LP | 411,454 | $1,252 萬 | 0.18% | +5,993+1.5% | 加碼 |
| Altrinsic Global Advisors LLC | 399,392 | $1,215 萬 | 0.39% | −45,495−10.2% | 減碼 |
| Dimensional Fund Advisors LP | 386,691 | $1,177 萬 | 0.00% | +30,852+8.7% | 加碼 |
| Eversept Partners, LP | 384,789 | $1,171 萬 | 0.97% | −65,712−14.6% | 減碼 |
| Nomura Holdings Inc | 372,480 | $1,135 萬 | 0.07% | −4,268−1.1% | 減碼 |
| Stifel Financial Corp | 357,948 | $1,089 萬 | 0.01% | −18,271−4.9% | 減碼 |
| International Biotechnology Trust PLC | 355,088 | $1,081 萬 | 2.41% | +310,307+692.9% | 加碼 |
| Nuveen Asset Management, LLC | 351,476 | $1,070 萬 | 0.00% | −277,000−44.1% | 減碼 |
| Barclays PLC | 329,938 | $1,004 萬 | 0.01% | −353−0.1% | 減碼 |
| Sio Capital Management, LLC | 322,566 | $981.6 萬 | 2.99% | +322,566 | 新進 |
| Baillie Gifford & Co | 315,820 | $961.1 萬 | 0.01% | +13,817+4.6% | 加碼 |
| BNP Paribas Arbitrage, SA | 306,253 | $931.9 萬 | 0.02% | +280,521+1,090.2% | 加碼 |
| Hudson Bay Capital Management LP | 305,000 | $928.1 萬 | 0.10% | +40,000+15.1% | 加碼 |
| Dowling & Yahnke LLC | 302,421 | $920.3 萬 | 0.44% | −1000.0% | 減碼 |
| Natixis | 300,797 | $915.3 萬 | 0.03% | +300,797 | 新進 |
| Cubist Systematic Strategies, LLC | 297,182 | $904.3 萬 | 0.09% | +210,428+242.6% | 加碼 |
| California Public Employees Retirement System | 284,424 | $865.5 萬 | 0.01% | −3,704−1.3% | 減碼 |
| Sicart Associates LLC | 282,531 | $862.8 萬 | 2.25% | −8,723−3.0% | 減碼 |
| Swiss National Bank | 279,300 | $849.9 萬 | 0.01% | −600−0.2% | 減碼 |
| Voloridge Investment Management, LLC | 266,845 | $812.0 萬 | 0.04% | +266,845 | 新進 |
| Raymond James & Associates | 257,985 | $785.0 萬 | 0.01% | −43,464−14.4% | 減碼 |
| Bank of Montreal | 229,407 | $716.7 萬 | 0.00% | −20,297−8.1% | 減碼 |
| Renaissance Technologies LLC | 230,814 | $702.4 萬 | 0.01% | +133,100+136.2% | 加碼 |
| Parametric Portfolio Associates LLC | 225,106 | $685.0 萬 | 0.00% | −6,400−2.8% | 減碼 |
| Morningstar Investment Services LLC | 219,432 | $667.9 萬 | 0.07% | +5,291+2.5% | 加碼 |
| Sector Gamma AS | 209,537 | $637.6 萬 | 1.50% | −54,333−20.6% | 減碼 |
| Susquehanna International Group, LLP | 204,255 | $621.5 萬 | 0.01% | +30,089+17.3% | 加碼 |
| MUFG Securities EMEA plc | 200,000 | $608.6 萬 | 0.13% | +200,000 | 新進 |
| Russell Investments Group, Ltd. | 194,145 | $590.6 萬 | 0.01% | −37,720−16.3% | 減碼 |
| UBS Group AG | 193,589 | $589.1 萬 | 0.00% | +60,777+45.8% | 加碼 |
| Balyasny Asset Management LLC | 193,120 | $587.7 萬 | 0.03% | +51,105+36.0% | 加碼 |
| Rafferty Asset Management, LLC | 189,639 | $577.1 萬 | 0.03% | +92,902+96.0% | 加碼 |
| Citigroup Inc | 186,047 | $566.1 萬 | 0.01% | +64,983+53.7% | 加碼 |
| California State Teachers Retirement System | 184,004 | $559.9 萬 | 0.01% | −41,987−18.6% | 減碼 |
| UBS Asset Management Americas Inc | 183,752 | $559.2 萬 | 0.00% | +3,087+1.7% | 加碼 |
| Pictet Asset Management SA | 183,087 | $557.1 萬 | 0.01% | +47,391+34.9% | 加碼 |
| Tudor Investment Corp Et Al | 178,386 | $542.8 萬 | 0.10% | −23,227−11.5% | 減碼 |
| Credit Suisse AG | 176,767 | $537.9 萬 | 0.00% | −5,895−3.2% | 減碼 |
| Majedie Asset Management Ltd | 175,508 | $534.7 萬 | 0.41% | 00.0% | 不變 |
| Tekla Capital Management LLC | 175,680 | $534.6 萬 | 0.17% | −146,841−45.5% | 減碼 |
| State Board of Administration of Florida Retirement System | 173,260 | $527.2 萬 | 0.01% | +11,322+7.0% | 加碼 |
| Tocqueville Asset Management L.P. | 170,405 | $518.5 萬 | 0.07% | +1,875+1.1% | 加碼 |
| Alps Advisors Inc | 163,424 | $497.3 萬 | 0.06% | +163,424 | 新進 |
| D. E. Shaw & Co., Inc. | 160,659 | $488.9 萬 | 0.01% | +34,553+27.4% | 加碼 |
| Legal & General Group Plc | 158,344 | $481.8 萬 | 0.00% | −9,077−5.4% | 減碼 |
| Sonora Investment Management Group, LLC | 156,790 | $477.1 萬 | 0.55% | +156,790 | 新進 |
| New York State Common Retirement Fund | 153,800 | $468.0 萬 | 0.00% | −87,359−36.2% | 減碼 |
| BLB&B Advisors, LLC | 150,935 | $459.3 萬 | 0.30% | −5,265−3.4% | 減碼 |
| Rhumbline Advisers | 139,749 | $425.3 萬 | 0.01% | +1,386+1.0% | 加碼 |
| Peregrine Capital Management LLC | 139,721 | $425.2 萬 | 0.09% | +3,934+2.9% | 加碼 |
| Invesco Ltd. | 132,242 | $402.4 萬 | 0.00% | −9,113−6.4% | 減碼 |
| Jump Financial, LLC | 120,500 | $366.7 萬 | 0.23% | +120,500 | 新進 |
| Private Advisor Group, LLC | 115,742 | $352.2 萬 | 0.03% | +71,637+162.4% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 112,525 | $342.4 萬 | 0.02% | +76,989+216.7% | 加碼 |
| DekaBank Deutsche Girozentrale | 109,476 | $334.7 萬 | 0.01% | +1,900+1.8% | 加碼 |
| Wolverine Trading, LLC | 108,529 | $331.4 萬 | 0.04% | +1,651+1.5% | 加碼 |
| Alliancebernstein L.P. | 103,214 | $314.1 萬 | 0.00% | +34,763+50.8% | 加碼 |
| Allspring Global Investments Holdings, LLC | 98,574 | $299.9 萬 | 0.00% | +98,574 | 新進 |
| State of New Jersey Common Pension Fund D | 95,234 | $289.8 萬 | 0.01% | +8,018+9.2% | 加碼 |
| Envestnet Asset Management Inc | 91,292 | $277.8 萬 | 0.00% | −11,130−10.9% | 減碼 |
| LPL Financial LLC | 88,666 | $269.8 萬 | 0.00% | +5,051+6.0% | 加碼 |
| AXA S.A. | 87,900 | $267.5 萬 | 0.01% | +30,700+53.7% | 加碼 |
| Gateway Investment Advisers LLC | 85,103 | $259.0 萬 | 0.02% | +46,971+123.2% | 加碼 |
| Davenport & Co LLC | 84,663 | $257.6 萬 | 0.02% | −37,640−30.8% | 減碼 |
| Public Employees Retirement System of Ohio | 84,661 | $257.6 萬 | 0.01% | −2,783−3.2% | 減碼 |