Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2021 年第 4 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2021/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 341
- 較 2021 年第 3 季 +20 家
- 持有股數
- 1.23 億
- 較 2021 年第 3 季 +170.8 萬 (+1.4%)
- 總市值
- $37.5 億
- 較 2021 年第 3 季 −$3.26 億 (−8.0%)
- 新進機構
- 59
- 另有 106 家加碼
- 清倉機構
- 39
- 另有 119 家減碼
另有 5 家機構在 2021 年第 3 季持有、還沒有申報 2021 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2021 年第 4 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2021 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Allianz Asset Management GmbH | 81,830 | $249.1 萬 | 0.00% | +62,120+315.2% | 加碼 |
| Parkman Healthcare Partners LLC | 80,238 | $244.2 萬 | 0.55% | −56,142−41.2% | 減碼 |
| PFS Investments Inc. | 76,179 | $231.8 萬 | 0.04% | −663−0.9% | 減碼 |
| Rhenman & Partners Asset Management AB | 75,000 | $229.1 萬 | 0.15% | 00.0% | 不變 |
| Guggenheim Capital LLC | 72,978 | $222.1 萬 | 0.01% | +10,341+16.5% | 加碼 |
| National Bank of Canada | 70,000 | $213.0 萬 | 0.01% | +70,000 | 新進 |
| PDT Partners, LLC | 67,697 | $206.0 萬 | 0.16% | +67,697 | 新進 |
| Voya Investment Management LLC | 65,508 | $199.3 萬 | 0.00% | +22,808+53.4% | 加碼 |
| Squarepoint Ops LLC | 61,340 | $186.7 萬 | 0.01% | −108,525−63.9% | 減碼 |
| Canada Pension Plan Investment Board | 57,924 | $176.3 萬 | 0.00% | +57,924 | 新進 |
| Point72 Asset Management, L.P. | 53,981 | $164.3 萬 | 0.01% | −165,319−75.4% | 減碼 |
| AlphaCrest Capital Management LLC | 52,907 | $161.0 萬 | 0.06% | +823+1.6% | 加碼 |
| Jane Street Group, LLC | 52,550 | $159.9 萬 | 0.00% | −11,926−18.5% | 減碼 |
| Erste Asset Management GmbH | 51,300 | $157.1 萬 | 0.03% | 00.0% | 不變 |
| Treasurer of the State of North Carolina | 50,846 | $154.7 萬 | 0.01% | +330+0.7% | 加碼 |
| Alpha DNA Investment Management LLC | 50,614 | $153.9 萬 | 0.98% | +50,614 | 新進 |
| Raymond James Financial Services Advisors, Inc. | 48,981 | $149.0 萬 | 0.00% | +2,825+6.1% | 加碼 |
| Pura Vida Investments, LLC | 48,544 | $147.7 萬 | 0.15% | +48,544 | 新進 |
| Assenagon Asset Management S.A. | 48,401 | $147.3 萬 | 0.01% | +42,379+703.7% | 加碼 |
| Jefferies Group LLC | 44,000 | $133.9 萬 | 0.02% | −137−0.3% | 減碼 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $127.8 萬 | 0.16% | 00.0% | 不變 |
| Bard Financial Services, Inc. | 41,520 | $126.3 萬 | 0.10% | +31,795+326.9% | 加碼 |
| Capital Counsel LLC | 40,580 | $123.5 萬 | 0.05% | 00.0% | 不變 |
| Algert Global LLC | 38,430 | $116.9 萬 | 0.15% | +14,956+63.7% | 加碼 |
| Janney Montgomery Scott LLC | 36,424 | $110.8 萬 | 0.00% | +2,271+6.6% | 加碼 |
| Group One Trading, L.P. | 36,268 | $110.4 萬 | 0.02% | +4,735+15.0% | 加碼 |
| Engineers Gate Manager LP | 34,380 | $104.6 萬 | 0.05% | +17,708+106.2% | 加碼 |
| Arizona State Retirement System | 34,190 | $104.0 萬 | 0.01% | −367−1.1% | 減碼 |
| Healthcare of Ontario Pension Plan Trust Fund | 34,069 | $103.7 萬 | 0.00% | +34,069 | 新進 |
| Trexquant Investment LP | 33,903 | $103.2 萬 | 0.06% | +20,606+155.0% | 加碼 |
| Macquarie Group Ltd | 32,549 | $99.1 萬 | 0.00% | +121+0.4% | 加碼 |
| Employees Retirement System of Texas | 32,409 | $98.6 萬 | 0.01% | 00.0% | 不變 |
| Principal Financial Group Inc | 31,755 | $96.6 萬 | 0.00% | −10,930−25.6% | 減碼 |
| Truist Financial Corp | 30,937 | $94.1 萬 | 0.00% | −40−0.1% | 減碼 |
| Amalgamated Bank | 29,324 | $89.2 萬 | 0.01% | +3,923+15.4% | 加碼 |
| Koss-Olinger Consulting, LLC | 29,161 | $88.7 萬 | 0.14% | +17,729+155.1% | 加碼 |
| Commonwealth Equity Services, LLC | 28,766 | $87.5 萬 | 0.00% | −9,352−24.5% | 減碼 |
| Ensign Peak Advisors, Inc | 28,330 | $86.2 萬 | 0.00% | +28,330 | 新進 |
| Capital Fund Management S.A. | 28,108 | $85.5 萬 | 0.02% | +28,108 | 新進 |
| First Foundation Advisors | 27,972 | $85.1 萬 | 0.03% | −7,774−21.7% | 減碼 |
| Eaton Vance Management | 27,692 | $84.3 萬 | 0.00% | +818+3.0% | 加碼 |
| HighTower Advisors, LLC | 27,138 | $82.6 萬 | 0.00% | +17,281+175.3% | 加碼 |
| Occudo Quantitative Strategies LP | 26,650 | $81.1 萬 | 0.07% | +26,650 | 新進 |
| Grandfield & Dodd, LLC | 26,771 | $81.0 萬 | 0.05% | +5,080+23.4% | 加碼 |
| AE Wealth Management LLC | 26,085 | $79.4 萬 | 0.01% | +26,085 | 新進 |
| Janus Henderson Group PLC | 25,716 | $78.3 萬 | 0.00% | +11,968+87.1% | 加碼 |
| Utah Retirement Systems | 25,409 | $77.3 萬 | 0.01% | +100+0.4% | 加碼 |
| MML Investors Services, LLC | 25,217 | $76.7 萬 | 0.01% | +603+2.4% | 加碼 |
| Teacher Retirement System of Texas | 24,454 | $74.4 萬 | 0.00% | +4,694+23.8% | 加碼 |
| Handelsbanken Fonder AB | 24,411 | $74.3 萬 | 0.00% | 00.0% | 不變 |
| ProShare Advisors LLC | 23,432 | $71.3 萬 | 0.00% | −10,067−30.1% | 減碼 |
| Storebrand Asset Management AS | 22,462 | $68.4 萬 | 0.00% | −12,204−35.2% | 減碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 22,121 | $67.3 萬 | 0.00% | +9,304+72.6% | 加碼 |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $63.8 萬 | 0.00% | 00.0% | 不變 |
| ExodusPoint Capital Management, LP | 19,788 | $60.2 萬 | 0.01% | +11,615+142.1% | 加碼 |
| Kestra Advisory Services, LLC | 19,681 | $59.9 萬 | 0.01% | −8,243−29.5% | 減碼 |
| Public Employees Retirement Association of Colorado | 19,604 | $59.7 萬 | 0.00% | 00.0% | 不變 |
| Profund Advisors LLC | 19,417 | $59.1 萬 | 0.02% | −3,474−15.2% | 減碼 |
| Advisor Group Holdings, Inc. | 19,147 | $58.3 萬 | 0.00% | +706+3.8% | 加碼 |
| US Bancorp | 19,115 | $58.2 萬 | 0.00% | +2,732+16.7% | 加碼 |
| Vestmark Advisory Solutions, Inc. | 18,578 | $56.5 萬 | 0.03% | −1,455−7.3% | 減碼 |
| Oppenheimer & Co Inc | 18,358 | $55.9 萬 | 0.01% | −2,769−13.1% | 減碼 |
| Stephens Inc | 17,701 | $53.9 萬 | 0.01% | −3,440−16.3% | 減碼 |
| Quantamental Technologies LLC | 17,671 | $53.8 萬 | 0.27% | +17,671 | 新進 |
| Campbell & CO Investment Adviser LLC | 17,346 | $52.8 萬 | 0.18% | −2,550−12.8% | 減碼 |
| State of Wisconsin Investment Board | 17,054 | $51.9 萬 | 0.00% | −525−3.0% | 減碼 |
| Natixis Advisors, L.P. | 15,895 | $48.4 萬 | 0.00% | −1,833−10.3% | 減碼 |
| Arden Trust Co | 15,554 | $47.4 萬 | 0.08% | −543−3.4% | 減碼 |
| Castle Rock Wealth Management, LLC | 15,593 | $46.6 萬 | 0.19% | 00.0% | 不變 |
| Creative Planning | 15,116 | $46.0 萬 | 0.00% | +201+1.3% | 加碼 |
| Xponance, Inc. | 14,890 | $45.3 萬 | 0.01% | +318+2.2% | 加碼 |
| Blair William & Co | 14,464 | $44.0 萬 | 0.00% | −50−0.3% | 減碼 |
| Deutsche Bank AG | 14,087 | $42.8 萬 | 0.00% | −36,859−72.3% | 減碼 |
| Lincoln National Corp | 14,070 | $42.8 萬 | 0.01% | −200−1.4% | 減碼 |
| Brookstone Capital Management | 13,947 | $42.4 萬 | 0.01% | +2,550+22.4% | 加碼 |
| Verition Fund Management LLC | 13,740 | $41.8 萬 | 0.01% | +13,740 | 新進 |
| North Star Asset Management Inc | 13,680 | $41.6 萬 | 0.02% | 00.0% | 不變 |
| Gsa Capital Partners LLP | 13,368 | $40.7 萬 | 0.05% | +13,368 | 新進 |
| Victory Capital Management Inc | 13,147 | $40.0 萬 | 0.00% | −192−1.4% | 減碼 |
| Wellington Management Group LLP | 13,134 | $39.9 萬 | 0.00% | +13,134 | 新進 |
| SG Americas Securities, LLC | 12,932 | $39.4 萬 | 0.00% | −6,789−34.4% | 減碼 |
| Brown Advisory Securities, LLC | 13,000 | $39.4 萬 | 0.17% | −2,500−16.1% | 減碼 |
| Cetera Advisor Networks LLC | 12,825 | $39.0 萬 | 0.00% | +273+2.2% | 加碼 |
| Shell Asset Management Co | 12,651 | $38.5 萬 | 0.01% | +48+0.4% | 加碼 |
| Virtus ETF Advisers LLC | 12,296 | $37.4 萬 | 0.14% | +194+1.6% | 加碼 |
| Comerica Bank | 11,755 | $37.0 萬 | 0.00% | −75−0.6% | 減碼 |
| Rockefeller Capital Management L.P. | 12,092 | $36.6 萬 | 0.00% | −1,320,688−99.1% | 減碼 |
| Caption Management, LLC | 12,000 | $36.6 萬 | 0.02% | −108,993−90.1% | 減碼 |
| Teza Capital Management LLC | 11,845 | $36.0 萬 | 0.10% | +11,845 | 新進 |
| Baird Financial Group, Inc. | 11,356 | $34.6 萬 | 0.00% | +2,407+26.9% | 加碼 |
| Vontobel Holding Ltd. | 11,310 | $34.4 萬 | 0.00% | +11,310 | 新進 |
| Plancorp, LLC | 11,274 | $34.3 萬 | 0.02% | +140+1.3% | 加碼 |
| SEI Investments Co | 11,194 | $33.9 萬 | 0.00% | −2,763−19.8% | 減碼 |
| Dynamic Technology Lab Private Ltd | 11,134 | $33.9 萬 | 0.04% | −366−3.2% | 減碼 |
| Greenup Street Wealth Management LLC | 11,145 | $33.9 萬 | 0.20% | +11,145 | 新進 |
| Walleye Trading LLC | 10,695 | $32.5 萬 | 0.01% | +1,076+11.2% | 加碼 |
| Cambridge Investment Research Advisors, Inc. | 10,447 | $31.8 萬 | 0.00% | −6,420−38.1% | 減碼 |
| Maryland State Retirement & Pension System | 9,956 | $30.3 萬 | 0.01% | 00.0% | 不變 |
| Oppenheimer Asset Management Inc. | 9,782 | $29.7 萬 | 0.00% | −1,100−10.1% | 減碼 |
| Ameriprise Financial Inc | 9,627 | $29.3 萬 | 0.00% | −1,272−11.7% | 減碼 |