Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2026 年第 1 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2026/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 497
- 較 2025 年第 4 季 +8 家
- 持有股數
- 1.73 億
- 較 2025 年第 4 季 +1,914 萬 (+12.5%)
- 總市值
- $129.7 億
- 較 2025 年第 4 季 +$8.28 億 (+6.8%)
- 新進機構
- 73
- 另有 179 家加碼
- 清倉機構
- 65
- 另有 158 家減碼
另有 5 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2026 年第 1 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 24,556,637 | $18.4 億 | 0.10% | +484,536+2.0% | 加碼 |
| Capital World Investors | 21,186,369 | $15.9 億 | 0.22% | +3,225,070+18.0% | 加碼 |
| BlackRock, Inc. | 10,442,476 | $7.84 億 | 0.01% | −205,387−1.9% | 減碼 |
| Vanguard Portfolio Management LLC | 7,808,902 | $5.86 億 | 0.03% | +7,808,902 | 新進 |
| Vanguard Capital Management LLC | 7,118,330 | $5.35 億 | 0.01% | +7,118,330 | 新進 |
| Wellington Management Group LLP | 6,391,816 | $4.80 億 | 0.09% | +131,491+2.1% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 6,159,027 | $4.62 億 | 0.32% | −2,948,992−32.4% | 減碼 |
| Two Sigma Investments, LP | 5,857,629 | $4.40 億 | 0.37% | +3,198,983+120.3% | 加碼 |
| Geode Capital Management, LLC | 3,984,332 | $3.05 億 | 0.02% | +835,483+26.5% | 加碼 |
| State Street Corp | 3,995,564 | $3.00 億 | 0.01% | +20,699+0.5% | 加碼 |
| Royal Bank of Canada | 3,801,815 | $2.85 億 | 0.05% | +2,683,018+239.8% | 加碼 |
| Price T Rowe Associates Inc | 3,025,251 | $2.27 億 | 0.03% | +37,411+1.3% | 加碼 |
| JPMorgan Chase & Co | 2,363,567 | $1.71 億 | 0.01% | +58,775+2.6% | 加碼 |
| Tweedy, Browne Co LLC | 2,275,625 | $1.71 億 | 13.57% | −189,305−7.7% | 減碼 |
| Artisan Partners Limited Partnership | 2,058,308 | $1.55 億 | 0.25% | +876,892+74.2% | 加碼 |
| Baker Bros. Advisors LP | 2,047,727 | $1.54 億 | 0.88% | +255,886+14.3% | 加碼 |
| Deerfield Management Company, L.P. (Series C) | 1,979,669 | $1.49 億 | 1.75% | 00.0% | 不變 |
| Deep Track Capital, LP | 1,950,000 | $1.46 億 | 3.02% | +250,000+14.7% | 加碼 |
| Bellevue Group AG | 1,818,665 | $1.37 億 | 3.25% | −2,983,534−62.1% | 減碼 |
| Goldman Sachs Group Inc | 1,699,847 | $1.28 億 | 0.02% | +843,881+98.6% | 加碼 |
| American Century Companies Inc | 1,663,803 | $1.25 億 | 0.06% | +46,697+2.9% | 加碼 |
| Charles Schwab Investment Management Inc | 1,583,266 | $1.19 億 | 0.02% | +41,425+2.7% | 加碼 |
| Franklin Resources Inc | 1,575,023 | $1.18 億 | 0.03% | +253,678+19.2% | 加碼 |
| UBS Asset Management Americas Inc | 1,475,632 | $1.11 億 | 0.02% | +87,065+6.3% | 加碼 |
| Pictet Asset Management Holding SA | 1,434,995 | $1.07 億 | 0.11% | +16,504+1.2% | 加碼 |
| Summit Partners Public Asset Management, LLC | 1,404,033 | $1.05 億 | 4.88% | −58,673−4.0% | 減碼 |
| Invesco Ltd. | 1,277,358 | $9,592 萬 | 0.01% | +8,068+0.6% | 加碼 |
| Millennium Management LLC | 1,051,506 | $7,896 萬 | 0.06% | +958,244+1,027.5% | 加碼 |
| Morgan Stanley | 1,026,509 | $7,708 萬 | 0.00% | +6,603+0.6% | 加碼 |
| Vanguard Fiduciary Trust Co | 1,024,377 | $7,692 萬 | 0.02% | +1,024,377 | 新進 |
| Citadel Advisors LLC | 942,534 | $7,077 萬 | 0.05% | −1,192,102−55.8% | 減碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 907,533 | $6,814 萬 | 0.08% | −445,304−32.9% | 減碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 874,089 | $6,564 萬 | 0.15% | −202,281−18.8% | 減碼 |
| Northern Trust Corp | 868,179 | $6,519 萬 | 0.01% | +21,461+2.5% | 加碼 |
| Bank of America Corp | 840,598 | $6,312 萬 | 0.00% | +57,019+7.3% | 加碼 |
| Polar Capital Holdings Plc | 829,511 | $6,229 萬 | 0.27% | −503,913−37.8% | 減碼 |
| Groupama Asset Managment | 824,540 | $6,191 萬 | 0.90% | +57,651+7.5% | 加碼 |
| UBS Group AG | 808,443 | $6,071 萬 | 0.01% | −236,598−22.6% | 減碼 |
| Nomura Asset Management International Inc. | 785,281 | $5,897 萬 | 0.10% | −79,611−9.2% | 減碼 |
| GW&K Investment Management, LLC | 779,349 | $5,852 萬 | 0.52% | −7,319−0.9% | 減碼 |
| Arrowstreet Capital, Limited Partnership | 737,859 | $5,541 萬 | 0.03% | −325,468−30.6% | 減碼 |
| Squarepoint Ops LLC | 695,276 | $5,221 萬 | 0.11% | +258,997+59.4% | 加碼 |
| Voloridge Investment Management, LLC | 672,858 | $5,052 萬 | 0.20% | +87,888+15.0% | 加碼 |
| Massachusetts Financial Services Co | 666,116 | $5,002 萬 | 0.02% | −146,631−18.0% | 減碼 |
| Ameriprise Financial Inc | 660,144 | $4,957 萬 | 0.01% | +61,396+10.3% | 加碼 |
| Nuveen, LLC | 648,496 | $4,870 萬 | 0.01% | −12,273−1.9% | 減碼 |
| Eversept Partners, LP | 632,100 | $4,746 萬 | 3.13% | +93,882+17.4% | 加碼 |
| Eventide Asset Management, LLC | 575,000 | $4,318 萬 | 0.71% | 00.0% | 不變 |
| TD Asset Management Inc | 529,954 | $3,979 萬 | 0.03% | −243,230−31.5% | 減碼 |
| Teacher Retirement System of Texas | 523,932 | $3,934 萬 | 0.16% | +101,033+23.9% | 加碼 |
| Bank of New York Mellon Corp | 514,617 | $3,864 萬 | 0.01% | −23,269−4.3% | 減碼 |
| Perceptive Advisors LLC | 504,000 | $3,785 萬 | 0.75% | +504,000 | 新進 |
| Boone Capital Management LLC | 500,522 | $3,758 萬 | 11.51% | +82,689+19.8% | 加碼 |
| Candriam Luxembourg S.C.A. | 484,053 | $3,635 萬 | 0.19% | −193,576−28.6% | 減碼 |
| BNP Paribas Arbitrage, SA | 479,460 | $3,600 萬 | 0.02% | +144,852+43.3% | 加碼 |
| Alyeska Investment Group, L.P. | 473,150 | $3,553 萬 | 0.10% | −8,561−1.8% | 減碼 |
| First Trust Advisors LP | 468,363 | $3,517 萬 | 0.03% | −56,876−10.8% | 減碼 |
| Neuberger Berman Group LLC | 443,272 | $3,329 萬 | 0.03% | +335,228+310.3% | 加碼 |
| Pinnacle Associates Ltd | 436,457 | $3,277 萬 | 0.42% | −25,511−5.5% | 減碼 |
| D. E. Shaw & Co., Inc. | 429,599 | $3,226 萬 | 0.03% | +96,796+29.1% | 加碼 |
| Alliancebernstein L.P. | 400,669 | $3,170 萬 | 0.01% | +58,820+17.2% | 加碼 |
| Davern Capital Partners, LP | 386,903 | $2,905 萬 | 7.97% | +148,426+62.2% | 加碼 |
| C WorldWide Group Holding A/S | 366,000 | $2,748 萬 | 0.59% | 00.0% | 不變 |
| New York State Common Retirement Fund | 350,414 | $2,631 萬 | 0.04% | +108,561+44.9% | 加碼 |
| Capital Research Global Investors | 323,015 | $2,426 萬 | 0.00% | +323,015 | 新進 |
| Renaissance Technologies LLC | 305,549 | $2,294 萬 | 0.04% | +81,942+36.6% | 加碼 |
| Swiss National Bank | 304,500 | $2,286 萬 | 0.01% | +6,000+2.0% | 加碼 |
| Hudson Bay Capital Management LP | 295,100 | $2,216 萬 | 0.13% | −179,900−37.9% | 減碼 |
| Legal & General Group Plc | 294,679 | $2,213 萬 | 0.01% | −30,469−9.4% | 減碼 |
| Privium Fund Management B.V. | 290,024 | $2,178 萬 | 4.53% | +49,200+20.4% | 加碼 |
| Barclays PLC | 289,874 | $2,177 萬 | 0.01% | −552,997−65.6% | 減碼 |
| ARK Investment Management LLC大師方舟投資 | 288,716 | $2,168 萬 | 0.17% | −134,252−31.7% | 減碼 |
| TimesSquare Capital Management, LLC | 275,674 | $2,070 萬 | 0.35% | +275,674 | 新進 |
| Dimensional Fund Advisors LP | 267,215 | $2,006 萬 | 0.00% | +91,180+51.8% | 加碼 |
| California Public Employees Retirement System | 255,485 | $1,918 萬 | 0.01% | +42,117+19.7% | 加碼 |
| HRT Financial LP | 252,250 | $1,894 萬 | 0.05% | +229,322+1,000.2% | 加碼 |
| Zurich Insurance Group Ltd | 239,645 | $1,799 萬 | 0.14% | −22,175−8.5% | 減碼 |
| Davenport & Co LLC | 238,238 | $1,789 萬 | 0.10% | +20,341+9.3% | 加碼 |
| J. Goldman & Co LP | 235,260 | $1,767 萬 | 0.82% | +167,621+247.8% | 加碼 |
| Raymond James Financial Inc | 235,121 | $1,766 萬 | 0.01% | −22,089−8.6% | 減碼 |
| ExodusPoint Capital Management, LP | 227,084 | $1,705 萬 | 0.17% | +143,209+170.7% | 加碼 |
| Orion Investment Co | 225,015 | $1,690 萬 | 5.38% | −146−0.1% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 219,652 | $1,649 萬 | 0.03% | +780.0% | 加碼 |
| Tocqueville Asset Management L.P. | 219,220 | $1,646 萬 | 0.24% | +15,490+7.6% | 加碼 |
| Handelsbanken Fonder AB | 213,911 | $1,606 萬 | 0.05% | +166,000+346.5% | 加碼 |
| Trexquant Investment LP | 213,645 | $1,604 萬 | 0.12% | +81,404+61.6% | 加碼 |
| Jump Financial, LLC | 206,675 | $1,552 萬 | 0.23% | +206,675 | 新進 |
| Stifel Financial Corp | 196,703 | $1,477 萬 | 0.01% | −2,160−1.1% | 減碼 |
| CI Private Wealth, LLC | 196,599 | $1,476 萬 | 0.02% | −19,839−9.2% | 減碼 |
| Jane Street Group, LLC | 191,818 | $1,440 萬 | 0.02% | +161,347+529.5% | 加碼 |
| Wells Fargo & Company | 189,853 | $1,426 萬 | 0.00% | −90,192−32.2% | 減碼 |
| HSBC Holdings PLC | 185,967 | $1,397 萬 | 0.01% | +159,026+590.3% | 加碼 |
| California State Teachers Retirement System | 176,485 | $1,325 萬 | 0.01% | +32,312+22.4% | 加碼 |
| Rhumbline Advisers | 173,440 | $1,302 萬 | 0.01% | −1,947−1.1% | 減碼 |
| Sector Gamma AS | 169,468 | $1,273 萬 | 3.00% | −15,509−8.4% | 減碼 |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 167,657 | $1,259 萬 | 0.01% | 00.0% | 不變 |
| Colony Group, LLC | 165,544 | $1,243 萬 | 0.01% | −16,273−9.0% | 減碼 |
| ADAR1 Capital Management, LLC | 160,338 | $1,204 萬 | 0.72% | +13,208+9.0% | 加碼 |
| Deutsche Bank AG | 159,891 | $1,201 萬 | 0.00% | +10,448+7.0% | 加碼 |
| Sicart Associates LLC | 159,412 | $1,197 萬 | 3.07% | −4,145−2.5% | 減碼 |