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Ionis Pharmaceuticals Inc

IONS
交易所
Nasdaq
產業
Pharmaceutical Preparations
SEC CIK
0000874015

近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、3 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。

2026 年第 1 季與 2025 年第 4 季比較

持有 Ionis Pharmaceuticals Inc 的機構從 2025 年第 4 季到 2026 年第 1 季的變化。

2026 年第 1 季全部持有人2025 年第 4 季全部持有人

IONS 的 13F 持有人：2025 年第 4 季與 2026 年第 1 季比較
項目2025 年第 4 季其中尚未申報 2026 年第 1 季2026 年第 1 季變化
持有家數4945497+8
股數1.70 億1,677 萬1.73 億+1,914 萬 (+12.5%)
市值$134.6 億$13.3 億$129.7 億+$8.28 億 (+6.8%)

5 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季：沒申報不算清倉，所以變化不計入它們。

新進機構（73 家）

2026 年第 1 季季末持有 Ionis Pharmaceuticals Inc、2025 年第 4 季季末沒有持有的機構。

2026 年第 1 季新進 IONS 的機構
機構股數市值佔組合 %
Vanguard Portfolio Management LLC7,808,902$5.86 億0.03%
Vanguard Capital Management LLC7,118,330$5.35 億0.01%
Vanguard Fiduciary Trust Co1,024,377$7,692 萬0.02%
Perceptive Advisors LLC504,000$3,785 萬0.75%
Capital Research Global Investors323,015$2,426 萬0.00%
TimesSquare Capital Management, LLC275,674$2,070 萬0.35%
Jump Financial, LLC206,675$1,552 萬0.23%
Capital Fund Management S.A.142,201$1,068 萬0.10%
Vanguard Asset Management, Ltd137,507$1,033 萬0.01%
Braidwell LP130,862$982.6 萬0.33%
Integral Health Asset Management, LLC125,000$938.6 萬0.50%
SEB Asset Management AB114,334$858.5 萬0.04%
Winton Group Ltd106,532$799.9 萬0.28%
Empowered Funds, LLC103,141$774.5 萬0.05%
CSS LLC79,093$593.9 萬0.33%
Vanguard Global Advisers, LLC71,911$540.0 萬0.00%
Edgestream Partners, L.P.68,369$513.4 萬0.17%
Polymer Capital Management (HK) LTD61,200$459.6 萬0.64%
Panagora Asset Management Inc57,446$431.4 萬0.02%
Carmignac Gestion53,000$398.0 萬0.06%
E Fund Management Co., Ltd.46,688$350.6 萬0.10%
Qube Research & Technologies Ltd42,856$321.8 萬0.00%
Polygon Management Ltd.41,764$313.6 萬0.62%
Vanguard Investments Australia, Ltd.38,557$289.5 萬0.01%
DeepCurrents Investment Group LLC27,422$205.9 萬0.08%
Entropy Technologies, LP27,207$204.3 萬0.09%
StemPoint Capital LP26,385$198.1 萬0.38%
Florida Financial Advisors, LLC25,886$194.4 萬0.47%
Allstate Corp20,565$154.4 萬0.02%
Readystate Asset Management LP20,436$153.5 萬0.09%
FORA Capital, LLC19,693$147.9 萬0.11%
Caption Management, LLC15,591$117.1 萬0.06%
Canada Pension Plan Investment Board14,100$105.9 萬0.00%
Highland Capital Management, LLC12,819$96.3 萬0.05%
Capstone Capital Management Ltd21,447$83.2 萬0.84%
Ground Swell Capital, LLC7,285$54.7 萬1.08%
Robeco Institutional Asset Management B.V.5,660$42.5 萬0.00%
Cynosure Management, LLC5,614$42.2 萬0.05%
Mesirow Financial Investment Management, Inc.5,460$41.0 萬0.01%
Virtu Financial LLC5,342$40.1 萬0.02%
R Squared Ltd4,359$32.7 萬0.18%
Intrust Bank NA4,056$30.5 萬0.02%
Optas, LLC4,034$30.3 萬0.05%
Congress Asset Management Co3,946$29.6 萬0.00%
Axq Capital, LP3,846$28.9 萬0.04%
Perigon Wealth Management, LLC3,430$25.8 萬0.00%
Gsa Capital Partners LLP3,172$23.8 萬0.01%
QRG Capital Management, Inc.3,094$23.2 萬0.00%
EntryPoint Capital, LLC2,963$22.2 萬0.07%
AlphaCore Capital LLC2,762$20.7 萬0.00%
Integrated Wealth Concepts LLC2,724$20.5 萬0.00%
New York Life Investment Management LLC2,688$20.2 萬0.00%
Fideuram Asset Management (Ireland) dac2,213$18.2 萬0.02%
Stephens Inc26,761$9.14 萬0.00%
Advisory Services Network, LLC604$4.54 萬0.00%
Mather Group, LLC.410$3.08 萬0.00%
Cassaday & Co Wealth Management LLC400$3.00 萬0.00%
RWM Asset Management, LLC375$2.82 萬0.00%
Cedar Mountain Advisors, LLC223$1.67 萬0.00%
Twin Peaks Wealth Advisors, LLC215$1.61 萬0.00%
CX Institutional202$1.50 萬0.00%
E Fund Management (Hong Kong) Co., Ltd.195$1.46 萬0.01%
Owl Creek Wealth Partners LLC170$1.28 萬0.00%
Main Street Group, LTD100$7,5090.00%
Clear Investment Research, LLC71$5,3310.01%
MCF Advisors LLC50$3,7550.00%
TD Waterhouse Canada Inc.48$3,6050.00%
Transamerica Financial Advisors, Inc.33$2,4770.00%
NBT Bank N A20$1,5020.00%
Whipplewood Advisors, LLC15$1,1260.00%
Caitong International Asset Management Co., Ltd7$5260.00%
Hughes Financial Services, LLC6$4510.00%
3 Factor Indexing, LLC2$1510.00%

清倉機構（65 家）

2025 年第 4 季季末持有 Ionis Pharmaceuticals Inc、2026 年第 1 季有申報但已經沒有持有的機構。

2026 年第 1 季清倉 IONS 的機構
機構2025 年第 4 季股數2025 年第 4 季市值
Two Sigma Advisers, LP3,052,111$2.41 億
Tri Locum Partners LP557,174$4,408 萬
Balyasny Asset Management LLC120,577$953.9 萬
Skandinaviska Enskilda Banken AB (publ)115,293$912.2 萬
Healthcare of Ontario Pension Plan Trust Fund110,000$870.2 萬
Simplex Trading, LLC96,647$764.6 萬
Bridgewater Associates, LP67,706$535.6 萬
BI Asset Management Fondsmaeglerselskab A/S62,073$491.1 萬
PDT Partners, LLC54,365$430.1 萬
Alpine Global Management, LLC53,600$424.0 萬
Mariner, LLC47,740$377.7 萬
Atika Capital Management LLC47,488$375.7 萬
Acadian Asset Management LLC34,691$274.1 萬
Twin Tree Management, LP32,476$256.9 萬
Verition Fund Management LLC22,685$179.5 萬
Gilder Gagnon Howe & Co LLC19,275$152.5 萬
Quantedge Capital Pte Ltd18,500$146.4 萬
Elo Mutual Pension Insurance Co18,417$145.7 萬
Cinctive Capital Management LP13,726$108.6 萬
Friedenthal Financial13,115$103.8 萬
Dark Forest Capital Management LP12,691$100.4 萬
Baader Bank INC11,097$86.6 萬
Ares Systematic Credit Ltd9,916$78.4 萬
Two Sigma Securities, LLC9,649$76.3 萬
NEOS Investment Management LLC8,557$67.7 萬
Persistent Asset Partners Ltd7,807$61.8 萬
Graham Capital Management, L.P.7,596$60.1 萬
Natixis6,087$48.2 萬
Dymon Asia Capital (Singapore) Pte. Ltd.5,350$42.3 萬
Skopos Labs, Inc.4,669$37.3 萬
AE Wealth Management LLC4,403$34.8 萬
Bank of Nova Scotia4,189$33.1 萬
Janney Montgomery Scott LLC4,177$33.0 萬
Avanza Fonder AB3,596$28.4 萬
Park Avenue Securities LLC3,571$28.3 萬
Cambridge Investment Research Advisors, Inc.2,957$23.4 萬
Impact Partnership Wealth, LLC2,905$23.0 萬
Axxcess Wealth Management, LLC2,877$22.8 萬
Clearbridge Investments, LLC2,715$21.5 萬
Kerntke Otto McGlone Wealth Management Group2,695$21.3 萬
IFG Advisory, LLC2,678$21.2 萬
PharVision Advisers, LLC2,661$21.1 萬
Motley Fool Asset Management LLC2,630$20.8 萬
Twin Lakes Capital Management, LLC1,500$11.9 萬
SRS Capital Advisors, Inc.774$6.12 萬
Clear Street Markets LLC748$5.92 萬
Quest Partners LLC670$5.30 萬
Laurel Wealth Advisors LLC600$4.75 萬
Daiwa Securities Group Inc.481$3.80 萬
Strategic Advocates LLC287$2.27 萬
SageView Advisory Group, LLC215$1.70 萬
Quarry LP180$1.42 萬
Torren Management, LLC137$1.08 萬
Garner Asset Management Corp115$9,098
Rakuten Securities, Inc.90$7,120
Kemnay Advisory Services Inc.71$5,617
Activest Wealth Management32$2,532
Optima Capital LLC12$949
Private Trust Co NA11$870
Marquette Asset Management, LLC7$554
Cape Investment Advisory, Inc.6$475
Bare Financial Services, Inc6$475
Rachor Investment Advisory Services, LLC4$317
Stone House Investment Management, LLC3$237
Avion Wealth6$0

尚未申報 2026 年第 1 季的機構（5 家）

2025 年第 4 季季末持有 Ionis Pharmaceuticals Inc、還沒有申報 2026 年第 1 季 13F 的機構。沒申報不代表賣出，所以不算清倉。

2025 年第 4 季持有 IONS、尚未申報 2026 年第 1 季的機構
機構2025 年第 4 季股數2025 年第 4 季市值
Vanguard Group Inc16,440,459$13.0 億
Norges Bank320,160$2,533 萬
Comerica Bank3,997$31.6 萬
Global Retirement Partners, LLC1,876$14.8 萬
CIBC Private Wealth Group, LLC99$7,832