Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、7 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 2 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 363
- 較 2025 年第 1 季 +21 家
- 持有股數
- 1.69 億
- 較 2025 年第 1 季 +213.9 萬 (+1.3%)
- 總市值
- $66.7 億
- 較 2025 年第 1 季 +$16.4 億 (+32.6%)
- 新進機構
- 80
- 另有 121 家加碼
- 清倉機構
- 59
- 另有 109 家減碼
另有 2 家機構在 2025 年第 1 季持有、還沒有申報 2025 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 2 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 23,642,990 | $9.34 億 | 0.05% | +29,405+0.1% | 加碼 |
| Vanguard Group Inc | 16,714,846 | $6.60 億 | 0.01% | +330,912+2.0% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 16,048,721 | $6.34 億 | 0.40% | −126,812−0.8% | 減碼 |
| Capital World Investors | 12,540,188 | $4.95 億 | 0.07% | +178,194+1.4% | 加碼 |
| BlackRock, Inc. | 10,896,937 | $4.31 億 | 0.01% | −367,505−3.3% | 減碼 |
| Bellevue Group AG | 7,853,198 | $3.10 億 | 6.84% | 00.0% | 不變 |
| Wellington Management Group LLP | 6,345,776 | $2.51 億 | 0.05% | −2,070,645−24.6% | 減碼 |
| Deep Track Capital, LP | 4,891,544 | $1.93 億 | 6.21% | +327,337+7.2% | 加碼 |
| State Street Corp | 4,530,398 | $1.79 億 | 0.01% | −314,735−6.5% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 3,800,000 | $1.50 億 | 0.25% | +2,724,400+253.3% | 加碼 |
| Price T Rowe Associates Inc | 3,126,073 | $1.24 億 | 0.01% | −138,961−4.3% | 減碼 |
| Tweedy, Browne Co LLC | 2,891,948 | $1.14 億 | 10.60% | −91,570−3.1% | 減碼 |
| Geode Capital Management, LLC | 2,891,095 | $1.14 億 | 0.01% | +48,141+1.7% | 加碼 |
| Two Sigma Advisers, LP | 2,667,611 | $1.05 億 | 0.22% | +575,600+27.5% | 加碼 |
| Millennium Management LLC | 2,649,527 | $1.05 億 | 0.09% | +2,014,157+317.0% | 加碼 |
| BVF Inc | 1,913,385 | $7,560 萬 | 2.70% | 00.0% | 不變 |
| Two Sigma Investments, LP | 1,788,367 | $7,066 萬 | 0.13% | +102,514+6.1% | 加碼 |
| UBS Group AG | 1,529,323 | $6,042 萬 | 0.01% | −361,279−19.1% | 減碼 |
| Citadel Advisors LLC | 1,494,981 | $5,907 萬 | 0.05% | −1,985,081−57.0% | 減碼 |
| Charles Schwab Investment Management Inc | 1,487,818 | $5,878 萬 | 0.01% | +44,189+3.1% | 加碼 |
| Macquarie Group Ltd | 1,434,073 | $5,666 萬 | 0.07% | −233,121−14.0% | 減碼 |
| Morgan Stanley | 1,362,209 | $5,382 萬 | 0.00% | +218,028+19.1% | 加碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,350,879 | $5,337 萬 | 0.13% | +154,487+12.9% | 加碼 |
| TD Asset Management Inc | 1,104,690 | $4,365 萬 | 0.04% | +4,224+0.4% | 加碼 |
| Polar Capital Holdings Plc | 1,000,000 | $3,951 萬 | 0.21% | +1,000,000 | 新進 |
| Bank of America Corp | 995,890 | $3,935 萬 | 0.00% | +228,458+29.8% | 加碼 |
| ARK Investment Management LLC大師方舟投資 | 900,318 | $3,557 萬 | 0.26% | −100,209−10.0% | 減碼 |
| Voloridge Investment Management, LLC | 854,634 | $3,377 萬 | 0.12% | +477,430+126.6% | 加碼 |
| Northern Trust Corp | 814,250 | $3,217 萬 | 0.00% | −20,597−2.5% | 減碼 |
| Royal Bank of Canada | 799,912 | $3,160 萬 | 0.01% | +183,831+29.8% | 加碼 |
| UBS Asset Management Americas Inc | 791,072 | $3,126 萬 | 0.01% | +131,637+20.0% | 加碼 |
| Goldman Sachs Group Inc | 777,940 | $3,074 萬 | 0.00% | +125,422+19.2% | 加碼 |
| Balyasny Asset Management LLC | 768,648 | $3,037 萬 | 0.07% | +768,648 | 新進 |
| Hudson Bay Capital Management LP | 750,000 | $2,963 萬 | 0.19% | −299,900−28.6% | 減碼 |
| Woodline Partners LP | 732,813 | $2,895 萬 | 0.15% | +732,813 | 新進 |
| Candriam Luxembourg S.C.A. | 724,740 | $2,864 萬 | 0.17% | −268,964−27.1% | 減碼 |
| Groupama Asset Managment | 660,957 | $2,683 萬 | 0.44% | +91,746+16.1% | 加碼 |
| Teacher Retirement System of Texas | 668,273 | $2,640 萬 | 0.11% | +167,822+33.5% | 加碼 |
| Pictet Asset Management Holding SA | 608,640 | $2,422 萬 | 0.02% | −9,910−1.6% | 減碼 |
| Eversept Partners, LP | 588,900 | $2,327 萬 | 2.34% | +71,879+13.9% | 加碼 |
| Barclays PLC | 583,266 | $2,304 萬 | 0.01% | +229,329+64.8% | 加碼 |
| AXA S.A. | 566,883 | $2,240 萬 | 0.06% | +397+0.1% | 加碼 |
| Bank of New York Mellon Corp | 527,188 | $2,083 萬 | 0.00% | −17,445−3.2% | 減碼 |
| Massachusetts Financial Services Co | 519,184 | $2,051 萬 | 0.01% | +519,184 | 新進 |
| Great Point Partners LLC | 500,000 | $1,976 萬 | 12.84% | +250,000+100.0% | 加碼 |
| Vestal Point Capital, LP | 500,000 | $1,976 萬 | 1.04% | +500,000 | 新進 |
| Pinnacle Associates Ltd | 494,539 | $1,954 萬 | 0.28% | −113,978−18.7% | 減碼 |
| Bank of Montreal | 483,289 | $1,909 萬 | 0.01% | −299,546−38.3% | 減碼 |
| American Century Companies Inc | 472,749 | $1,868 萬 | 0.01% | +355,981+304.9% | 加碼 |
| Norges Bank | 450,254 | $1,779 萬 | 0.00% | −407,974−47.5% | 減碼 |
| C WorldWide Group Holding A/S | 450,000 | $1,778 萬 | 0.24% | +50,000+12.5% | 加碼 |
| Schonfeld Strategic Advisors LLC | 449,206 | $1,775 萬 | 0.13% | −111,153−19.8% | 減碼 |
| GW&K Investment Management, LLC | 448,830 | $1,773 萬 | 0.16% | +266,521+146.2% | 加碼 |
| Standard Life Aberdeen plc | 406,694 | $1,625 萬 | 0.03% | −39,503−8.9% | 減碼 |
| Legal & General Group Plc | 404,366 | $1,598 萬 | 0.00% | +65,904+19.5% | 加碼 |
| Great Lakes Advisors, LLC | 399,646 | $1,579 萬 | 0.13% | +399,646 | 新進 |
| JPMorgan Chase & Co | 394,978 | $1,561 萬 | 0.00% | −26,533−6.3% | 減碼 |
| Ameriprise Financial Inc | 368,119 | $1,454 萬 | 0.00% | +7,931+2.2% | 加碼 |
| Artisan Partners Limited Partnership | 354,962 | $1,402 萬 | 0.02% | +151,784+74.7% | 加碼 |
| Citigroup Inc | 340,977 | $1,347 萬 | 0.01% | −85,503−20.0% | 減碼 |
| Sovran Advisors, LLC | 321,913 | $1,331 萬 | 1.39% | −6,991−2.1% | 減碼 |
| Point72 Asset Management, L.P. | 292,647 | $1,156 萬 | 0.03% | +5,443+1.9% | 加碼 |
| Swiss National Bank | 288,600 | $1,140 萬 | 0.01% | +13,300+4.8% | 加碼 |
| Sector Gamma AS | 285,842 | $1,129 萬 | 3.69% | 00.0% | 不變 |
| Renaissance Technologies LLC | 270,714 | $1,070 萬 | 0.01% | +117,200+76.3% | 加碼 |
| Privium Fund Management B.V. | 267,594 | $1,069 萬 | 2.31% | 00.0% | 不變 |
| Connor, Clark & Lunn Investment Management Ltd. | 265,793 | $1,050 萬 | 0.04% | +136,520+105.6% | 加碼 |
| Invesco Ltd. | 256,235 | $1,012 萬 | 0.00% | −618,599−70.7% | 減碼 |
| Nuveen, LLC | 245,085 | $968.3 萬 | 0.00% | −63,692−20.6% | 減碼 |
| CI Private Wealth, LLC | 237,840 | $939.7 萬 | 0.01% | +707+0.3% | 加碼 |
| Verition Fund Management LLC | 232,687 | $919.3 萬 | 0.05% | +180,400+345.0% | 加碼 |
| Orion Investment Co | 217,370 | $858.8 萬 | 3.06% | +2,080+1.0% | 加碼 |
| Raymond James Financial Inc | 210,592 | $832.0 萬 | 0.00% | +61,902+41.6% | 加碼 |
| Wells Fargo & Company | 209,857 | $829.1 萬 | 0.00% | −46,376−18.1% | 減碼 |
| California Public Employees Retirement System | 201,993 | $798.1 萬 | 0.01% | +10,989+5.8% | 加碼 |
| Edmond de Rothschild Holding S.A. | 197,600 | $780.7 萬 | 0.12% | +73,400+59.1% | 加碼 |
| Stifel Financial Corp | 196,357 | $775.8 萬 | 0.01% | −4,585−2.3% | 減碼 |
| Tocqueville Asset Management L.P. | 187,345 | $740.2 萬 | 0.11% | −500.0% | 減碼 |
| Sicart Associates LLC | 185,296 | $732.1 萬 | 2.56% | −350−0.2% | 減碼 |
| Rhenman & Partners Asset Management AB | 182,000 | $719.1 萬 | 0.91% | +101,000+124.7% | 加碼 |
| Rhumbline Advisers | 181,599 | $717.5 萬 | 0.01% | −6,617−3.5% | 減碼 |
| BNP Paribas Arbitrage, SA | 177,762 | $702.3 萬 | 0.01% | −130,531−42.3% | 減碼 |
| Sonora Investment Management Group, LLC | 163,172 | $644.7 萬 | 0.48% | +9,025+5.9% | 加碼 |
| Alyeska Investment Group, L.P. | 159,008 | $628.2 萬 | 0.02% | +159,008 | 新進 |
| Aquatic Capital Management LLC | 158,086 | $624.6 萬 | 0.13% | +1,929+1.2% | 加碼 |
| State Board of Administration of Florida Retirement System | 153,895 | $608.0 萬 | 0.01% | +1,580+1.0% | 加碼 |
| BLB&B Advisors, LLC | 151,550 | $598.8 萬 | 0.28% | −650−0.4% | 減碼 |
| Tang Capital Management LLC | 150,000 | $592.6 萬 | 0.30% | 00.0% | 不變 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 149,839 | $592.0 萬 | 0.01% | +5,969+4.1% | 加碼 |
| ADAR1 Capital Management, LLC | 148,461 | $586.6 萬 | 0.95% | +148,461 | 新進 |
| J. Goldman & Co LP | 147,682 | $583.5 萬 | 0.18% | −160,088−52.0% | 減碼 |
| California State Teachers Retirement System | 145,104 | $573.3 萬 | 0.01% | +12,866+9.7% | 加碼 |
| Rafferty Asset Management, LLC | 144,770 | $572.0 萬 | 0.02% | −31,478−17.9% | 減碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 139,739 | $552.1 萬 | 0.00% | −2,694−1.9% | 減碼 |
| Nikko Asset Management Americas, Inc. | 139,739 | $551.8 萬 | 0.06% | −2,694−1.9% | 減碼 |
| Squarepoint Ops LLC | 134,395 | $531.0 萬 | 0.01% | −170,978−56.0% | 減碼 |
| Kennedy Capital Management, Inc. | 132,045 | $521.7 萬 | 0.12% | −18,379−12.2% | 減碼 |
| Trexquant Investment LP | 128,869 | $509.2 萬 | 0.06% | +128,869 | 新進 |
| Exome Asset Management LLC | 121,116 | $478.5 萬 | 3.95% | −14,500−10.7% | 減碼 |
| Healthcare of Ontario Pension Plan Trust Fund | 116,000 | $458.3 萬 | 0.01% | +116,000 | 新進 |