Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 2 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 363
- 較 2025 年第 1 季 +21 家
- 持有股數
- 1.69 億
- 較 2025 年第 1 季 +213.9 萬 (+1.3%)
- 總市值
- $66.7 億
- 較 2025 年第 1 季 +$16.4 億 (+32.6%)
- 新進機構
- 80
- 另有 121 家加碼
- 清倉機構
- 59
- 另有 109 家減碼
另有 2 家機構在 2025 年第 1 季持有、還沒有申報 2025 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 2 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Neuberger Berman Group LLC | 114,623 | $452.9 萬 | 0.00% | +12,150+11.9% | 加碼 |
| HSBC Holdings PLC | 108,294 | $429.4 萬 | 0.00% | +33,461+44.7% | 加碼 |
| SEI Investments Co | 98,348 | $388.6 萬 | 0.00% | +26,790+37.4% | 加碼 |
| Superstring Capital Management LP | 98,267 | $388.3 萬 | 4.84% | +98,267 | 新進 |
| State of Wisconsin Investment Board | 96,694 | $382.0 萬 | 0.01% | −11,622−10.7% | 減碼 |
| DekaBank Deutsche Girozentrale | 93,807 | $371.7 萬 | 0.01% | 00.0% | 不變 |
| Susquehanna Portfolio Strategies, LLC | 92,900 | $367.0 萬 | 0.08% | +92,900 | 新進 |
| DCF Advisers, LLC | 91,750 | $362.5 萬 | 1.74% | −3,250−3.4% | 減碼 |
| Nicola Wealth Management Ltd. | 87,000 | $343.7 萬 | 0.32% | 00.0% | 不變 |
| New York State Common Retirement Fund | 86,972 | $343.6 萬 | 0.00% | +8,711+11.1% | 加碼 |
| Deutsche Bank AG | 85,278 | $336.9 萬 | 0.00% | +468+0.6% | 加碼 |
| Manufacturers Life Insurance Company, The | 83,386 | $329.5 萬 | 0.00% | −54−0.1% | 減碼 |
| Marex Group plc | 83,361 | $329.4 萬 | 0.06% | +83,361 | 新進 |
| UBS Oconnor LLC | 81,251 | $321.0 萬 | 0.09% | −9,528−10.5% | 減碼 |
| Worldquant Millennium Advisors LLC | 74,438 | $294.1 萬 | 0.01% | +74,438 | 新進 |
| Van Eck Associates Corp | 73,617 | $290.9 萬 | 0.00% | +71,460+3,312.9% | 加碼 |
| Treasurer of the State of North Carolina | 72,587 | $286.8 萬 | 0.01% | +994+1.4% | 加碼 |
| Walleye Capital LLC | 66,482 | $262.7 萬 | 0.02% | −28,508−30.0% | 減碼 |
| Davenport & Co LLC | 64,843 | $256.2 萬 | 0.01% | +8,450+15.0% | 加碼 |
| Voya Investment Management LLC | 64,517 | $254.9 萬 | 0.00% | +750+1.2% | 加碼 |
| Janus Henderson Group PLC | 63,877 | $252.3 萬 | 0.00% | 00.0% | 不變 |
| Lazard Asset Management LLC | 60,749 | $240.0 萬 | 0.00% | −90.0% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 59,723 | $236.0 萬 | 0.02% | +2,174+3.8% | 加碼 |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $235.5 萬 | 0.01% | 00.0% | 不變 |
| State of New Jersey Common Pension Fund D | 58,918 | $232.8 萬 | 0.01% | −1,744−2.9% | 減碼 |
| Raiffeisen Bank International AG | 56,754 | $226.9 萬 | 0.03% | +15,000+35.9% | 加碼 |
| First Trust Advisors LP | 56,519 | $223.3 萬 | 0.00% | +56,519 | 新進 |
| PDT Partners, LLC | 54,365 | $214.8 萬 | 0.12% | −41,691−43.4% | 減碼 |
| Ensign Peak Advisors, Inc | 53,320 | $210.7 萬 | 0.00% | −1,780−3.2% | 減碼 |
| Creative Planning | 53,289 | $210.5 萬 | 0.00% | +17,167+47.5% | 加碼 |
| Alliancebernstein L.P. | 52,057 | $205.7 萬 | 0.00% | −48,692−48.3% | 減碼 |
| Erste Asset Management GmbH | 51,300 | $204.2 萬 | 0.02% | 00.0% | 不變 |
| Capital Counsel LLC | 50,205 | $198.4 萬 | 0.08% | +13,125+35.4% | 加碼 |
| Public Employees Retirement System of Ohio | 48,244 | $190.6 萬 | 0.01% | +67+0.1% | 加碼 |
| Great West Life Assurance Co | 46,501 | $184.1 萬 | 0.00% | +2,648+6.0% | 加碼 |
| Schroder Investment Management Group | 45,950 | $181.5 萬 | 0.00% | 00.0% | 不變 |
| Arizona State Retirement System | 44,040 | $174.0 萬 | 0.01% | +3,353+8.2% | 加碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 43,615 | $172.3 萬 | 0.00% | +7,106+19.5% | 加碼 |
| Handelsbanken Fonder AB | 43,211 | $170.7 萬 | 0.01% | 00.0% | 不變 |
| Granite Investment Partners, LLC | 43,181 | $170.6 萬 | 0.08% | −25,253−36.9% | 減碼 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $165.9 萬 | 0.20% | 00.0% | 不變 |
| Guggenheim Capital LLC | 40,857 | $161.4 萬 | 0.01% | −557−1.3% | 減碼 |
| Simplex Trading, LLC | 39,638 | $156.6 萬 | 0.04% | −24,943−38.6% | 減碼 |
| Prelude Capital Management, LLC | 39,423 | $155.8 萬 | 0.15% | +1,651+4.4% | 加碼 |
| Algert Global LLC | 38,090 | $150.5 萬 | 0.03% | +38,090 | 新進 |
| Blair William & Co | 37,891 | $149.7 萬 | 0.00% | −490−1.3% | 減碼 |
| Y-Intercept (Hong Kong) Ltd | 37,649 | $148.8 萬 | 0.04% | +37,649 | 新進 |
| Grandfield & Dodd, LLC | 37,230 | $147.1 萬 | 0.09% | −531−1.4% | 減碼 |
| Mariner, LLC | 36,914 | $145.8 萬 | 0.00% | +3,431+10.2% | 加碼 |
| Engineers Gate Manager LP | 33,118 | $130.8 萬 | 0.02% | +33,118 | 新進 |
| Brevan Howard Capital Management LP | 32,732 | $129.3 萬 | 0.01% | +9,759+42.5% | 加碼 |
| Nomura Holdings Inc | 32,161 | $127.1 萬 | 0.01% | −204,265−86.4% | 減碼 |
| China Universal Asset Management Co., Ltd. | 31,966 | $126.3 萬 | 0.12% | +80+0.3% | 加碼 |
| KLP Kapitalforvaltning AS | 31,500 | $124.5 萬 | 0.01% | +4,100+15.0% | 加碼 |
| Capital Fund Management S.A. | 31,219 | $123.3 萬 | 0.01% | −26,795−46.2% | 減碼 |
| Pathstone Holdings, LLC | 30,759 | $121.5 萬 | 0.00% | −3,613−10.5% | 減碼 |
| One Capital Management, LLC | 29,865 | $118.0 萬 | 0.04% | +29,865 | 新進 |
| Future Fund LLC | 29,595 | $116.9 萬 | 0.52% | +29,595 | 新進 |
| Entropy Technologies, LP | 29,452 | $116.4 萬 | 0.09% | +29,452 | 新進 |
| Profund Advisors LLC | 28,859 | $114.0 萬 | 0.04% | −6,028−17.3% | 減碼 |
| NEOS Investment Management LLC | 28,161 | $111.3 萬 | 0.01% | +3,020+12.0% | 加碼 |
| Tema ETFs LLC | 28,161 | $111.3 萬 | 0.30% | +3,020+12.0% | 加碼 |
| Daiwa Securities Group Inc. | 26,141 | $103.2 萬 | 0.00% | +4,000+18.1% | 加碼 |
| Alpine Global Management, LLC | 25,437 | $100.5 萬 | 0.23% | −2,660−9.5% | 減碼 |
| LPL Financial LLC | 24,872 | $98.3 萬 | 0.00% | +906+3.8% | 加碼 |
| Teachers Retirement System of the State of Kentucky | 24,083 | $95.2 萬 | 0.01% | 00.0% | 不變 |
| Xponance, Inc. | 22,754 | $89.9 萬 | 0.01% | +2,435+12.0% | 加碼 |
| Oxford Asset Management LLP | 22,405 | $88.5 萬 | 0.29% | +22,405 | 新進 |
| Jefferies Financial Group Inc. | 22,381 | $88.4 萬 | 0.01% | −460−2.0% | 減碼 |
| Graham Capital Management, L.P. | 20,935 | $82.7 萬 | 0.03% | +20,935 | 新進 |
| Nicollet Investment Management, Inc. | 20,747 | $82.0 萬 | 0.27% | −704−3.3% | 減碼 |
| Victory Capital Management Inc | 18,516 | $73.2 萬 | 0.00% | −125−0.7% | 減碼 |
| Bleakley Financial Group, LLC | 18,129 | $71.6 萬 | 0.02% | −4,155−18.6% | 減碼 |
| Assenagon Asset Management S.A. | 17,654 | $69.8 萬 | 0.00% | +17,654 | 新進 |
| Quantinno Capital Management LP | 17,542 | $69.3 萬 | 0.00% | +9,027+106.0% | 加碼 |
| Fieldview Capital Management, LLC | 17,306 | $68.4 萬 | 0.10% | +17,306 | 新進 |
| SummitTX Capital, L.P. | 17,149 | $67.8 萬 | 0.03% | −17,954−51.1% | 減碼 |
| North Star Asset Management Inc | 16,610 | $65.6 萬 | 0.03% | +3,000+22.0% | 加碼 |
| Bayesian Capital Management, LP | 16,600 | $65.6 萬 | 0.10% | +8,100+95.3% | 加碼 |
| E Fund Management Co., Ltd. | 16,160 | $63.8 萬 | 0.03% | −311−1.9% | 減碼 |
| Public Employees Retirement Association of Colorado | 15,589 | $61.6 萬 | 0.00% | 00.0% | 不變 |
| Significant Wealth Partners LLC | 15,504 | $61.3 萬 | 0.30% | +1,899+14.0% | 加碼 |
| Corton Capital Inc. | 14,424 | $57.0 萬 | 0.66% | +14,424 | 新進 |
| Vestmark Advisory Solutions, Inc. | 14,341 | $56.7 萬 | 0.01% | +14,341 | 新進 |
| Gotham Asset Management, LLC | 14,279 | $56.4 萬 | 0.00% | +14,279 | 新進 |
| Commonwealth Equity Services, LLC | 13,942 | $55.1 萬 | 0.00% | −2,456−15.0% | 減碼 |
| Envestnet Asset Management Inc | 13,544 | $53.5 萬 | 0.00% | −1,495−9.9% | 減碼 |
| Davy Global Fund Management Ltd | 13,263 | $52.4 萬 | 0.05% | +5,204+64.6% | 加碼 |
| Marshall Wace, LLP | 13,100 | $51.8 萬 | 0.00% | +3,998+43.9% | 加碼 |
| Westmount Partners, LLC | 12,961 | $51.2 萬 | 0.14% | 00.0% | 不變 |
| Annis Gardner Whiting Capital Advisors, LLC | 12,801 | $50.6 萬 | 0.18% | +2,065+19.2% | 加碼 |
| Paloma Partners Management Co | 12,557 | $49.6 萬 | 0.11% | +12,557 | 新進 |
| Virtus Investment Advisers, Inc. | 12,476 | $49.3 萬 | 0.17% | +2,775+28.6% | 加碼 |
| DnB Asset Management AS | 12,271 | $48.5 萬 | 0.00% | +12,271 | 新進 |
| Northwestern Mutual Wealth Management Co | 12,244 | $48.4 萬 | 0.00% | −114−0.9% | 減碼 |
| Brown Advisory Inc | 12,191 | $48.2 萬 | 0.00% | +165+1.4% | 加碼 |
| JustInvest LLC | 12,072 | $47.7 萬 | 0.01% | +1,759+17.1% | 加碼 |
| Vident Advisory, LLC | 12,000 | $47.4 萬 | 0.01% | +12,000 | 新進 |
| Horizon Kinetics Asset Management LLC | 11,952 | $47.2 萬 | 0.01% | −524−4.2% | 減碼 |
| Wiley Bros.-Aintree Capital, LLC | 11,758 | $46.5 萬 | 0.00% | +754+6.9% | 加碼 |