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Ionis Pharmaceuticals Inc

IONS
交易所
Nasdaq
產業
Pharmaceutical Preparations
SEC CIK
0000874015

近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。

2025 年第 2 季與 2025 年第 1 季比較

持有 Ionis Pharmaceuticals Inc 的機構從 2025 年第 1 季到 2025 年第 2 季的變化。

2025 年第 2 季全部持有人2025 年第 1 季全部持有人

IONS 的 13F 持有人：2025 年第 1 季與 2025 年第 2 季比較
項目2025 年第 1 季其中尚未申報 2025 年第 2 季2025 年第 2 季變化
持有家數3442363+21
股數1.67 億7,1541.69 億+213.9 萬 (+1.3%)
市值$50.3 億$21.6 萬$66.7 億+$16.4 億 (+32.6%)

2 家機構在 2025 年第 1 季持有、還沒有申報 2025 年第 2 季：沒申報不算清倉，所以變化不計入它們。

新進機構（80 家）

2025 年第 2 季季末持有 Ionis Pharmaceuticals Inc、2025 年第 1 季季末沒有持有的機構。

2025 年第 2 季新進 IONS 的機構
機構股數市值佔組合 %
Polar Capital Holdings Plc1,000,000$3,951 萬0.21%
Balyasny Asset Management LLC768,648$3,037 萬0.07%
Woodline Partners LP732,813$2,895 萬0.15%
Massachusetts Financial Services Co519,184$2,051 萬0.01%
Vestal Point Capital, LP500,000$1,976 萬1.04%
Great Lakes Advisors, LLC399,646$1,579 萬0.13%
Alyeska Investment Group, L.P.159,008$628.2 萬0.02%
ADAR1 Capital Management, LLC148,461$586.6 萬0.95%
Trexquant Investment LP128,869$509.2 萬0.06%
Healthcare of Ontario Pension Plan Trust Fund116,000$458.3 萬0.01%
Superstring Capital Management LP98,267$388.3 萬4.84%
Susquehanna Portfolio Strategies, LLC92,900$367.0 萬0.08%
Marex Group plc83,361$329.4 萬0.06%
Worldquant Millennium Advisors LLC74,438$294.1 萬0.01%
First Trust Advisors LP56,519$223.3 萬0.00%
Algert Global LLC38,090$150.5 萬0.03%
Y-Intercept (Hong Kong) Ltd37,649$148.8 萬0.04%
Engineers Gate Manager LP33,118$130.8 萬0.02%
One Capital Management, LLC29,865$118.0 萬0.04%
Future Fund LLC29,595$116.9 萬0.52%
Entropy Technologies, LP29,452$116.4 萬0.09%
Oxford Asset Management LLP22,405$88.5 萬0.29%
Graham Capital Management, L.P.20,935$82.7 萬0.03%
Assenagon Asset Management S.A.17,654$69.8 萬0.00%
Fieldview Capital Management, LLC17,306$68.4 萬0.10%
Corton Capital Inc.14,424$57.0 萬0.66%
Vestmark Advisory Solutions, Inc.14,341$56.7 萬0.01%
Gotham Asset Management, LLC14,279$56.4 萬0.00%
Paloma Partners Management Co12,557$49.6 萬0.11%
DnB Asset Management AS12,271$48.5 萬0.00%
Vident Advisory, LLC12,000$47.4 萬0.01%
Fox Run Management, L.L.C.10,988$43.4 萬0.07%
Westfield Capital Management Co LP9,561$37.8 萬0.00%
Perbak Capital Partners LLP9,538$37.7 萬0.09%
Fred Alger Management, LLC9,464$37.4 萬0.00%
Wealth Enhancement Advisory Services, LLC7,915$34.0 萬0.00%
Aigen Investment Management, LP8,298$32.8 萬0.04%
Atria Investments LLC8,186$32.3 萬0.00%
M&T Bank Corp7,651$30.3 萬0.00%
Jacobs Levy Equity Management, Inc6,813$26.9 萬0.00%
Meeder Advisory Services, Inc.6,644$26.3 萬0.01%
Frank, Rimerman Advisors LLC5,763$22.8 萬0.02%
Wedmont Private Capital5,282$22.6 萬0.01%
Brinker Capital Investments, LLC5,600$22.1 萬0.00%
Savant Capital, LLC5,570$22.0 萬0.00%
Franklin Resources Inc5,556$22.0 萬0.00%
Castle Rock Wealth Management, LLC5,122$21.5 萬0.05%
Callan Family Office, LLC5,400$21.3 萬0.01%
HighTower Advisors, LLC5,357$21.2 萬0.00%
Pinnacle Wealth Planning Services, Inc.5,284$20.9 萬0.03%
Empowered Funds, LLC5,067$20.0 萬0.00%
Wexford Capital LP4,749$18.8 萬0.05%
STRS Ohio3,714$14.7 萬0.00%
Allianz SE2,100$8.30 萬0.00%
Harvest Fund Management Co., Ltd1,829$7.20 萬0.00%
Capital Advisors, Ltd. LLC295$1.20 萬0.00%
Global X Japan Co., Ltd.259$1.02 萬0.00%
MTM Investment Management, LLC258$1.02 萬0.00%
Westside Investment Management, Inc.231$9,2260.00%
Twin Peaks Wealth Advisors, LLC215$8,9030.00%
Atlantic Union Bankshares Corp200$7,9020.00%
Ameritas Advisory Services, LLC146$5,7680.00%
Geneos Wealth Management Inc.139$5,4920.00%
WPG Advisers, LLC70$2,7660.00%
Asset Dedication, LLC59$2,3320.00%
TD Private Client Wealth LLC44$1,7380.00%
Rossby Financial, LCC34$1,3430.00%
Hantz Financial Services, Inc.36$1,0000.00%
Principia Wealth Advisory, LLC25$9880.00%
Cromwell Holdings LLC18$7110.00%
Fortitude Family Office, LLC17$6720.00%
Global Retirement Partners, LLC16$6320.00%
Horizon Investments, LLC15$5930.00%
Quaker Wealth Management, LLC14$5540.00%
Cornerstone Planning Group LLC12$5170.00%
Rothschild Investment LLC10$3950.00%
Parkworth Wealth Management, Inc.8$3160.00%
Kayne Anderson Rudnick Investment Management LLC7$2770.00%
IMA Wealth, Inc.5$1980.00%
WealthTrak Capital Management LLC5$1980.00%

清倉機構（59 家）

2025 年第 1 季季末持有 Ionis Pharmaceuticals Inc、2025 年第 2 季有申報但已經沒有持有的機構。

2025 年第 2 季清倉 IONS 的機構
機構2025 年第 1 季股數2025 年第 1 季市值
OrbiMed Advisors LLC2,540,136$7,664 萬
Camber Capital Management LP725,000$2,187 萬
Baker Bros. Advisors LP357,915$1,080 萬
Susquehanna Fundamental Investments, LLC158,609$478.5 萬
Susquehanna International Group, LLP71,811$216.7 萬
Sphera Funds Management Ltd.63,821$192.5 萬
Avidity Partners Management LP60,000$181.0 萬
Jane Street Group, LLC54,117$163.3 萬
Readystate Asset Management LP46,394$140.0 萬
Allostery Investments LP35,000$105.6 萬
Private Advisor Group, LLC34,531$104.2 萬
Liontrust Investment Partners LLP30,390$91.7 萬
Axq Capital, LP30,104$90.8 萬
ExodusPoint Capital Management, LP26,261$79.2 萬
HRT Financial LP25,824$77.9 萬
BlueCrest Capital Management Ltd24,800$74.8 萬
Castle Hook Partners LP23,940$72.2 萬
Toroso Investments, LLC21,833$65.9 萬
Bridgefront Capital, LLC20,528$61.9 萬
SG Americas Securities, LLC20,050$60.5 萬
NBT Bank N A17,050$51.4 萬
Virginia Retirement Systems Et Al16,522$49.8 萬
Twinbeech Capital LP15,938$48.1 萬
Point72 Hong Kong Ltd12,862$38.8 萬
XTX Topco Ltd12,404$37.4 萬
Intech Investment Management LLC12,207$36.8 萬
SIH Partners, LLLP11,999$36.2 萬
FORA Capital, LLC11,570$34.9 萬
Twin Tree Management, LP11,385$34.3 萬
Capula Management Ltd10,382$31.3 萬
Walleye Trading LLC9,361$28.2 萬
Amundi3,873$11.0 萬
Quarry LP3,000$9.05 萬
Corebridge Financial, Inc.2,657$8.02 萬
Sandia Investment Management LP2,500$7.54 萬
Coldstream Capital Management Inc2,345$7.08 萬
Point72 Asia (Singapore) Pte. Ltd.2,082$6.28 萬
Laurel Wealth Advisors LLC600$1.81 萬
Riverview Trust Co476$1.44 萬
Mather Group, LLC.410$1.24 萬
Quadrant Capital Group LLC381$1.15 萬
Oakworth Capital, Inc.300$9,051
Ronald Blue Trust, Inc.259$7,814
Newbridge Financial Services Group, Inc.200$6,034
Whittier Trust Co192$5,790
Smartleaf Asset Management LLC131$4,080
Anderson Financial Strategies, LLC121$3,651
First Horizon Advisors, Inc.112$3,379
Picton Mahoney Asset Management89$3,000
Dynamic Wealth Strategies, LLC80$2,414
Blume Capital Management, Inc.55$1,660
Quent Capital, LLC53$1,599
Wolff Wiese Magana LLC41$1,237
Avion Wealth54$1,000
Caitong International Asset Management Co., Ltd28$845
Bokf, NA18$543
Hexagon Capital Partners LLC9$272
Umb Bank N A6$181
MV Capital Management, Inc.3$91

尚未申報 2025 年第 2 季的機構（2 家）

2025 年第 1 季季末持有 Ionis Pharmaceuticals Inc、還沒有申報 2025 年第 2 季 13F 的機構。沒申報不代表賣出，所以不算清倉。

2025 年第 1 季持有 IONS、尚未申報 2025 年第 2 季的機構
機構2025 年第 1 季股數2025 年第 1 季市值
Tanaka Capital Management Inc6,714$20.3 萬
Lindbrook Capital, LLC440$1.33 萬