Ionis Pharmaceuticals Inc

IONS

交易所: Nasdaq
產業: Pharmaceutical Preparations
SEC CIK: 0000874015

SEC 申報列表（在新分頁開啟）

近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、3 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。

2025 年第 1 季與 2024 年第 4 季比較

持有 Ionis Pharmaceuticals Inc 的機構從 2024 年第 4 季到 2025 年第 1 季的變化。

2025 年第 1 季全部持有人 2024 年第 4 季全部持有人

IONS 的 13F 持有人：2024 年第 4 季與 2025 年第 1 季比較
項目	2024 年第 4 季	其中尚未申報 2025 年第 1 季	2025 年第 1 季	變化
持有家數	356	6	344	−6
股數	1.60 億	42.3 萬	1.67 億	+668.6 萬 (+4.2%)
市值	$56.1 億	$1,480 萬	$50.3 億	−$5.65 億 (−10.1%)

6 家機構在 2024 年第 4 季持有、還沒有申報 2025 年第 1 季：沒申報不算清倉，所以變化不計入它們。

新進機構（54 家）

2025 年第 1 季季末持有 Ionis Pharmaceuticals Inc、2024 年第 4 季季末沒有持有的機構。

2025 年第 1 季新進 IONS 的機構
機構	股數	市值	佔組合 %
BVF Inc	1,913,385	$5,773 萬	2.35%
Nuveen, LLC	308,777	$931.6 萬	0.00%
Point72 Asset Management, L.P.	287,204	$866.5 萬	0.02%
Universal- Beteiligungs- und Servicegesellschaft mbH	143,870	$434.1 萬	0.01%
Edmond de Rothschild Holding S.A.	124,200	$374.7 萬	0.07%
American Century Companies Inc	116,768	$352.3 萬	0.00%
Simplex Trading, LLC	64,581	$194.8 萬	0.07%
Avidity Partners Management LP	60,000	$181.0 萬	0.37%
Capital Fund Management S.A.	58,014	$175.0 萬	0.02%
Readystate Asset Management LP	46,394	$140.0 萬	0.07%
Point72 (DIFC) Ltd	41,347	$124.7 萬	0.12%
SummitTX Capital, L.P.	35,103	$105.9 萬	0.05%
Axq Capital, LP	30,104	$90.8 萬	0.36%
Alpine Global Management, LLC	28,097	$84.8 萬	0.22%
ExodusPoint Capital Management, LP	26,261	$79.2 萬	0.01%
HRT Financial LP	25,824	$77.9 萬	0.00%
Virginia Retirement Systems Et Al	16,522	$49.8 萬	0.00%
Twinbeech Capital LP	15,938	$48.1 萬	0.01%
Point72 Hong Kong Ltd	12,862	$38.8 萬	0.03%
Intech Investment Management LLC	12,207	$36.8 萬	0.00%
SIH Partners, LLLP	11,999	$36.2 萬	0.03%
FORA Capital, LLC	11,570	$34.9 萬	0.04%
Capula Management Ltd	10,382	$31.3 萬	0.00%
Virtus Investment Advisers, Inc.	9,701	$29.3 萬	0.08%
Jain Global LLC	8,595	$25.9 萬	0.01%
Quantinno Capital Management LP	8,515	$25.7 萬	0.00%
Bayesian Capital Management, LP	8,500	$25.6 萬	0.04%
Davy Global Fund Management Ltd	8,059	$24.3 萬	0.03%
Fiduciary Trust Co	7,738	$23.3 萬	0.00%
Semanteon Capital Management, LP	7,543	$22.8 萬	0.12%
Prudential Financial Inc	6,263	$21.0 萬	0.00%
Moisand Fitzgerald Tamayo, LLC	5,000	$15.1 萬	0.02%
Coldstream Capital Management Inc	2,345	$7.08 萬	0.00%
Point72 Asia (Singapore) Pte. Ltd.	2,082	$6.28 萬	0.02%
Ancora Advisors, LLC	2,000	$6.03 萬	0.00%
Quest Partners LLC	635	$1.92 萬	0.00%
Eastern Bank	300	$9,051	0.00%
Oakworth Capital, Inc.	300	$9,051	0.00%
Wealth Preservation Advisors, LLC	150	$4,526	0.00%
Kestra Investment Management, LLC	137	$4,134	0.00%
Anderson Financial Strategies, LLC	121	$3,651	0.00%
South State Corp.	119	$3,590	0.00%
MPWM Advisory Solutions, LLC	110	$3,319	0.00%
Picton Mahoney Asset Management	89	$3,000	0.00%
Meeder Asset Management Inc	95	$2,866	0.00%
Dynamic Wealth Strategies, LLC	80	$2,414	0.00%
Bessemer Group Inc	73	$2,000	0.00%
Truvestments Capital LLC	40	$1,207	0.00%
Highline Wealth Partners LLC	38	$1,146	0.00%
Cheviot Value Management, LLC	28	$942	0.00%
True Wealth Design, LLC	13	$393	0.00%
Bruce G. Allen Investments, LLC	13	$392	0.00%
Hexagon Capital Partners LLC	9	$272	0.00%
Umb Bank N A	6	$181	0.00%

清倉機構（60 家）

2024 年第 4 季季末持有 Ionis Pharmaceuticals Inc、2025 年第 1 季有申報但已經沒有持有的機構。

2025 年第 1 季清倉 IONS 的機構
機構	2024 年第 4 季股數	2024 年第 4 季市值
Clearbridge Investments, LLC	1,618,220	$5,657 萬
Vestal Point Capital, LP	595,000	$2,080 萬
Jacobs Levy Equity Management, Inc	281,813	$985.2 萬
Siren, L.L.C.	250,000	$874.0 萬
Driehaus Capital Management LLC	180,002	$629.3 萬
Alyeska Investment Group, L.P.	150,000	$524.4 萬
Assenagon Asset Management S.A.	141,917	$496.1 萬
Woodline Partners LP	107,610	$376.2 萬
Ghisallo Capital Management LLC	100,000	$349.6 萬
Dimensional Fund Advisors LP	94,157	$329.2 萬
Trexquant Investment LP	84,913	$296.9 萬
Fieldview Capital Management, LLC	51,282	$179.3 萬
Qsemble Capital Management, LP	46,573	$162.8 萬
D. E. Shaw & Co., Inc.	23,123	$80.8 萬
Canada Pension Plan Investment Board	19,900	$69.6 萬
Aigen Investment Management, LP	17,723	$62.0 萬
Natixis	16,626	$58.1 萬
Campbell & CO Investment Adviser LLC	15,681	$54.8 萬
Inceptionr LLC	14,390	$50.3 萬
Natixis Advisors, L.P.	14,313	$50.0 萬
Franklin Resources Inc	13,301	$46.5 萬
Stratos Wealth Partners, LTD.	12,813	$44.8 萬
Essential Planning, LLC.	11,440	$42.8 萬
Landscape Capital Management, L.L.C.	10,270	$35.9 萬
Syon Capital LLC	10,119	$35.4 萬
Janney Montgomery Scott LLC	9,840	$34.4 萬
Torno Capital, LLC	9,500	$33.2 萬
Virtus ETF Advisers LLC	9,448	$33.0 萬
Y-Intercept (Hong Kong) Ltd	9,407	$32.9 萬
Wolverine Trading, LLC	8,847	$30.9 萬
Truist Financial Corp	6,847	$23.9 萬
EntryPoint Capital, LLC	6,382	$22.3 萬
Gotham Asset Management, LLC	6,260	$21.9 萬
Castle Rock Wealth Management, LLC	6,972	$21.6 萬
M&T Bank Corp	6,096	$21.4 萬
Vontobel Holding Ltd.	5,865	$20.5 萬
Stevens Capital Management LP	5,860	$20.5 萬
Caption Management, LLC	5,417	$18.9 萬
Venturi Wealth Management, LLC	3,061	$10.7 萬
Horizon Investments, LLC	1,174	$4.10 萬
Elequin Capital LP	325	$1.14 萬
Global X Japan Co., Ltd.	297	$1.04 萬
Tidemark, LLC	200	$6,992
Capital Advisors, Ltd. LLC	179	$6,000
Whittier Trust Co of Nevada Inc	157	$5,484
LRI Investments, LLC	136	$4,755
Transce3nd, LLC	100	$3,496
Bryn Mawr Trust Co	92	$3,216
Raleigh Capital Management Inc.	72	$2,517
Coppell Advisory Solutions LLC	51	$1,781
Private Trust Co NA	48	$1,678
Cornerstone Planning Group LLC	25	$851
Lee Danner & Bass Inc	22	$769
Front Row Advisors LLC	20	$699
Central Trust Co	15	$525
WealthTrak Capital Management LLC	10	$350
Principia Wealth Advisory, LLC	9	$315
Rothschild Investment LLC	5	$175
Activest Wealth Management	1	$35
Sandy Spring Bank	0	$9

尚未申報 2025 年第 1 季的機構（6 家）

2024 年第 4 季季末持有 Ionis Pharmaceuticals Inc、還沒有申報 2025 年第 1 季 13F 的機構。沒申報不代表賣出，所以不算清倉。

2024 年第 4 季持有 IONS、尚未申報 2025 年第 1 季的機構
機構	2024 年第 4 季股數	2024 年第 4 季市值
Nuveen Asset Management, LLC	290,954	$1,017 萬
Swedbank AB	124,237	$434.3 萬
AlphaCentric Advisors LLC	7,614	$26.6 萬
AlphaMark Advisors, LLC	369	$1.30 萬
Global Retirement Partners, LLC	72	$2,517
Cassady Schiller Wealth Management, LLC	2	$70