Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2026 年第 2 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2026/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 515
- 較 2026 年第 1 季 +21 家
- 持有股數
- 1.80 億
- 較 2026 年第 1 季 +718.6 萬 (+4.2%)
- 總市值
- $142.6 億
- 較 2026 年第 1 季 +$13.0 億 (+10.0%)
- 新進機構
- 67
- 另有 199 家加碼
- 清倉機構
- 46
- 另有 162 家減碼
另有 3 家機構在 2026 年第 1 季持有、還沒有申報 2026 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2026 年第 2 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2026 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Sicart Associates LLC | 160,694 | $1,274 萬 | 3.12% | +1,282+0.8% | 加碼 |
| HRT Financial LP | 156,798 | $1,243 萬 | 0.02% | −95,452−37.8% | 減碼 |
| Vanguard Asset Management, Ltd | 155,088 | $1,230 萬 | 0.01% | +17,581+12.8% | 加碼 |
| CSS LLC | 152,289 | $1,207 萬 | 0.54% | +73,196+92.5% | 加碼 |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 151,301 | $1,200 萬 | 0.01% | −16,356−9.8% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 150,000 | $1,189 萬 | 0.02% | +100,000+200.0% | 加碼 |
| Colony Group, LLC | 147,917 | $1,173 萬 | 0.01% | −17,627−10.6% | 減碼 |
| Hudson Bay Capital Management LP | 145,000 | $1,150 萬 | 0.05% | −150,100−50.9% | 減碼 |
| Artia Global Partners LP | 144,376 | $1,145 萬 | 2.18% | 00.0% | 不變 |
| Fisher Asset Management, LLC | 137,184 | $1,088 萬 | 0.00% | −4,360−3.1% | 減碼 |
| HealthInvest Partners AB | 137,131 | $1,087 萬 | 2.93% | +109,258+392.0% | 加碼 |
| Lazard Asset Management LLC | 132,480 | $1,050 萬 | 0.02% | +107,070+421.4% | 加碼 |
| State Board of Administration of Florida Retirement System | 131,818 | $1,045 萬 | 0.02% | −4,060−3.0% | 減碼 |
| SEI Investments Co | 127,868 | $1,014 萬 | 0.01% | −29,354−18.7% | 減碼 |
| EFG International AG | 122,804 | $973.8 萬 | 0.18% | +28,824+30.7% | 加碼 |
| Gotham Asset Management, LLC | 121,252 | $961.4 萬 | 0.02% | +22,284+22.5% | 加碼 |
| Manufacturers Life Insurance Company, The | 120,678 | $956.9 萬 | 0.01% | −28,860−19.3% | 減碼 |
| Braidwell LP | 116,762 | $925.8 萬 | 0.34% | −14,100−10.8% | 減碼 |
| Norges Bank | 114,359 | $906.8 萬 | 0.00% | +114,359 | 新進 |
| SEB Asset Management AB | 114,334 | $906.6 萬 | 0.03% | 00.0% | 不變 |
| Edmond de Rothschild Holding S.A. | 113,320 | $898.5 萬 | 0.12% | −23,870−17.4% | 減碼 |
| Squarepoint Ops LLC | 109,379 | $867.3 萬 | 0.02% | −585,897−84.3% | 減碼 |
| Kennedy Capital Management, Inc. | 106,342 | $843.2 萬 | 0.15% | −5,488−4.9% | 減碼 |
| Envestnet Asset Management Inc | 98,124 | $778.0 萬 | 0.00% | +4,742+5.1% | 加碼 |
| Polygon Management Ltd. | 97,173 | $770.5 萬 | 1.25% | +55,409+132.7% | 加碼 |
| Swedbank AB | 95,666 | $758.5 萬 | 0.01% | +63,413+196.6% | 加碼 |
| State of Wisconsin Investment Board | 94,492 | $749.2 萬 | 0.02% | −1,999−2.1% | 減碼 |
| Public Employees Retirement Association of Colorado | 90,589 | $718.3 萬 | 0.02% | +75,000+481.1% | 加碼 |
| CenterBook Partners LP | 89,280 | $707.9 萬 | 0.35% | −61,632−40.8% | 減碼 |
| Exome Asset Management LLC | 88,177 | $699.2 萬 | 4.31% | −21,887−19.9% | 減碼 |
| Citigroup Inc | 86,746 | $687.8 萬 | 0.00% | −59,795−40.8% | 減碼 |
| DekaBank Deutsche Girozentrale | 93,807 | $677.7 萬 | 0.01% | 00.0% | 不變 |
| Dimensional Fund Advisors LP | 84,748 | $672.0 萬 | 0.00% | −182,467−68.3% | 減碼 |
| Russell Investments Group, Ltd. | 81,319 | $644.8 萬 | 0.01% | +18,400+29.2% | 加碼 |
| Fred Alger Management, LLC | 78,932 | $625.9 萬 | 0.02% | +50,480+177.4% | 加碼 |
| China Universal Asset Management Co., Ltd. | 76,302 | $605.0 萬 | 0.36% | −1,013−1.3% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 75,061 | $595.2 萬 | 0.04% | +7,738+11.5% | 加碼 |
| SG Americas Securities, LLC | 74,589 | $591.4 萬 | 0.00% | +11,294+17.8% | 加碼 |
| Erste Asset Management GmbH | 71,800 | $579.4 萬 | 0.05% | 00.0% | 不變 |
| Future Fund LLC | 71,362 | $565.8 萬 | 1.62% | +12,630+21.5% | 加碼 |
| Hillsdale Investment Management Inc. | 70,900 | $562.2 萬 | 0.13% | 00.0% | 不變 |
| Treasurer of the State of North Carolina | 70,021 | $555.2 萬 | 0.01% | +2,320+3.4% | 加碼 |
| Bank of Nova Scotia | 68,548 | $543.5 萬 | 0.01% | +68,548 | 新進 |
| Jupiter Topco LLC | 68,191 | $540.8 萬 | 0.00% | +68,191 | 新進 |
| Ameriprise Financial Inc | 67,705 | $536.8 萬 | 0.00% | −592,439−89.7% | 減碼 |
| Y-Intercept (Hong Kong) Ltd | 67,374 | $534.2 萬 | 0.11% | +67,374 | 新進 |
| Great Lakes Advisors, LLC | 66,924 | $530.6 萬 | 0.04% | −52,002−43.7% | 減碼 |
| Voya Investment Management LLC | 66,303 | $525.7 萬 | 0.00% | −2,833−4.1% | 減碼 |
| Victory Capital Management Inc | 65,967 | $523.1 萬 | 0.00% | −42,777−39.3% | 減碼 |
| Vanguard Global Advisers, LLC | 65,858 | $522.2 萬 | 0.00% | −6,053−8.4% | 減碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 65,077 | $516.0 萬 | 0.01% | +4,838+8.0% | 加碼 |
| Quantinno Capital Management LP | 64,914 | $514.7 萬 | 0.01% | +9,412+17.0% | 加碼 |
| Van Eck Associates Corp | 63,396 | $502.7 萬 | 0.00% | +28,891+83.7% | 加碼 |
| Thrivent Financial for Lutherans | 62,743 | $497.5 萬 | 0.01% | +52,781+529.8% | 加碼 |
| Panagora Asset Management Inc | 61,125 | $484.7 萬 | 0.01% | +3,679+6.4% | 加碼 |
| Stanley-Laman Group, Ltd. | 60,842 | $482.4 萬 | 0.49% | +21,536+54.8% | 加碼 |
| XTX Topco Ltd | 60,776 | $481.9 萬 | 0.06% | −19,743−24.5% | 減碼 |
| Schroder Investment Management Group | 58,865 | $475.0 萬 | 0.00% | +58,865 | 新進 |
| Rhenman & Partners Asset Management AB | 59,900 | $474.9 萬 | 0.45% | −33,000−35.5% | 減碼 |
| Sovran Advisors, LLC | 84,984 | $470.0 萬 | 0.35% | +84,984 | 新進 |
| Edgestream Partners, L.P. | 56,715 | $449.7 萬 | 0.13% | −11,654−17.0% | 減碼 |
| One Capital Management, LLC | 58,939 | $442.6 萬 | 0.12% | 00.0% | 不變 |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 53,795 | $426.5 萬 | 0.13% | −474−0.9% | 減碼 |
| Nicola Wealth Management Ltd. | 52,000 | $412.3 萬 | 0.47% | 00.0% | 不變 |
| KBC Group NV | 51,127 | $405.4 萬 | 0.01% | +20,914+69.2% | 加碼 |
| State of New Jersey Common Pension Fund D | 50,743 | $402.3 萬 | 0.01% | −1,845−3.5% | 減碼 |
| Creative Planning | 50,554 | $400.8 萬 | 0.00% | −1,674−3.2% | 減碼 |
| Campbell & CO Investment Adviser LLC | 49,632 | $393.5 萬 | 0.21% | +46,531+1,500.5% | 加碼 |
| Capital Counsel LLC | 49,580 | $393.1 萬 | 0.15% | 00.0% | 不變 |
| Toroso Investments, LLC | 49,178 | $389.9 萬 | 0.01% | +14,746+42.8% | 加碼 |
| Worldquant Millennium Advisors LLC | 48,976 | $388.3 萬 | 0.01% | +21,052+75.4% | 加碼 |
| Jones Financial Companies LLLP | 47,442 | $385.1 萬 | 0.00% | +20,719+77.5% | 加碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 47,836 | $379.3 萬 | 0.00% | −34,040−41.6% | 減碼 |
| Nikko Asset Management Americas, Inc. | 47,656 | $377.9 萬 | 0.05% | −34,040−41.7% | 減碼 |
| Public Employees Retirement System of Ohio | 46,862 | $371.6 萬 | 0.01% | +832+1.8% | 加碼 |
| Natixis Advisors, L.P. | 44,728 | $354.6 萬 | 0.00% | +21,007+88.6% | 加碼 |
| Arizona State Retirement System | 43,302 | $343.3 萬 | 0.02% | +1,036+2.5% | 加碼 |
| Aquatic Capital Management LLC | 42,581 | $337.6 萬 | 0.12% | −104,798−71.1% | 減碼 |
| Guggenheim Capital LLC | 41,405 | $328.3 萬 | 0.02% | −2,645−6.0% | 減碼 |
| Assenagon Asset Management S.A. | 40,927 | $324.5 萬 | 0.00% | +7,254+21.5% | 加碼 |
| J. Goldman & Co LP | 40,366 | $320.1 萬 | 0.11% | −194,894−82.8% | 減碼 |
| Jefferies Financial Group Inc. | 38,665 | $306.6 萬 | 0.03% | −20,400−34.5% | 減碼 |
| Exchange Traded Concepts, LLC | 38,627 | $306.3 萬 | 0.02% | +4,686+13.8% | 加碼 |
| Vanguard Investments Australia, Ltd. | 38,557 | $305.7 萬 | 0.01% | 00.0% | 不變 |
| STRS Ohio | 38,166 | $302.6 萬 | 0.01% | +9,384+32.6% | 加碼 |
| Rafferty Asset Management, LLC | 37,648 | $298.5 萬 | 0.01% | −22,660−37.6% | 減碼 |
| DCF Advisers, LLC | 37,500 | $297.3 萬 | 0.78% | −18,500−33.0% | 減碼 |
| Grandfield & Dodd, LLC | 37,077 | $294.0 萬 | 0.15% | −249−0.7% | 減碼 |
| KLP Kapitalforvaltning AS | 37,000 | $293.4 萬 | 0.01% | +3,100+9.1% | 加碼 |
| Entropy Technologies, LP | 36,815 | $291.9 萬 | 0.12% | +9,608+35.3% | 加碼 |
| DeepCurrents Investment Group LLC | 36,212 | $287.1 萬 | 0.10% | +8,790+32.1% | 加碼 |
| ExodusPoint Capital Management, LP | 35,645 | $282.6 萬 | 0.03% | −191,439−84.3% | 減碼 |
| Raiffeisen Bank International AG | 35,000 | $282.4 萬 | 0.03% | −1,000−2.8% | 減碼 |
| Prudential Financial Inc | 35,338 | $280.2 萬 | 0.00% | +70+0.2% | 加碼 |
| Pathstone Holdings, LLC | 34,004 | $269.6 萬 | 0.01% | +1,169+3.6% | 加碼 |
| Canada Pension Plan Investment Board | 33,300 | $264.0 萬 | 0.00% | +19,200+136.2% | 加碼 |
| Jain Global LLC | 32,931 | $261.1 萬 | 0.03% | +6,646+25.3% | 加碼 |
| Ethic Inc. | 31,679 | $251.2 萬 | 0.03% | +31,679 | 新進 |
| Blair William & Co | 31,606 | $250.6 萬 | 0.01% | −2,251−6.6% | 減碼 |
| Trexquant Investment LP | 31,538 | $250.1 萬 | 0.02% | −182,107−85.2% | 減碼 |