Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 356
- +9 vs. Q3 2024
- Shares held
- 160.5M
- +3.10M (+2.0%) vs. Q3 2024
- Total value
- $5.61B
- −$692.3M (−11.0%) vs. Q3 2024
- New holders
- 58
- 119 more added
- Sold out
- 49
- 121 more reduced
7 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| AllSquare Wealth Management LLC | 198 | $6.92K | 0.00% | 00.0% | Unchanged |
| Whittier Trust Co | 192 | $6.71K | 0.00% | −22−10.3% | Reduced |
| Exchange Traded Concepts, LLC | 178 | $6.22K | 0.00% | −17−8.7% | Reduced |
| Capital Advisors, Ltd. LLC | 179 | $6.00K | 0.00% | +179 | New |
| Whittier Trust Co of Nevada Inc | 157 | $5.48K | 0.00% | 00.0% | Unchanged |
| Pacifica Partners Inc. | 150 | $5.20K | 0.00% | 00.0% | Unchanged |
| LRI Investments, LLC | 136 | $4.75K | 0.00% | 00.0% | Unchanged |
| Golden State Wealth Management, LLC | 126 | $4.41K | 0.00% | +126 | New |
| Spire Wealth Management | 125 | $4.37K | 0.00% | 00.0% | Unchanged |
| GPS Wealth Strategies Group, LLC | 119 | $4.16K | 0.00% | 00.0% | Unchanged |
| First Horizon Advisors, Inc. | 112 | $3.92K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 104 | $3.64K | 0.00% | 00.0% | Unchanged |
| Creekmur Asset Management LLC | 100 | $3.50K | 0.00% | 00.0% | Unchanged |
| Transce3nd, LLC | 100 | $3.50K | 0.00% | +100 | New |
| Bryn Mawr Trust Co | 92 | $3.22K | 0.00% | 00.0% | Unchanged |
| Skopos Labs, Inc. | 80 | $2.80K | 0.00% | −4−4.8% | Reduced |
| Orion Capital Management LLC | 80 | $2.80K | 0.00% | +80 | New |
| Quent Capital, LLC | 74 | $2.59K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 72 | $2.52K | 0.00% | −29−28.7% | Reduced |
| Raleigh Capital Management Inc. | 72 | $2.52K | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 71 | $2.48K | 0.00% | 00.0% | Unchanged |
| Bogart Wealth, LLC | 71 | $2.48K | 0.00% | 00.0% | Unchanged |
| Semmax Financial Advisors Inc. | 79 | $2.40K | 0.00% | 00.0% | Unchanged |
| Principal Securities, Inc. | 67 | $2.34K | 0.00% | +63+1,575.0% | Added |
| Leonteq Securities AG | 63 | $2.20K | 0.00% | 00.0% | Unchanged |
| Hemington Wealth Management | 83 | $2.00K | 0.00% | −1−1.2% | Reduced |
| Versant Capital Management, Inc | 55 | $1.92K | 0.00% | −8−12.7% | Reduced |
| Blume Capital Management, Inc. | 55 | $1.92K | 0.00% | 00.0% | Unchanged |
| Clear Investment Research, LLC | 51 | $1.78K | 0.00% | 00.0% | Unchanged |
| Coppell Advisory Solutions LLC | 51 | $1.78K | 0.00% | +51 | New |
| Private Trust Co NA | 48 | $1.68K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 45 | $1.57K | 0.00% | +19+73.1% | Added |
| MV Capital Management, Inc. | 43 | $1.50K | 0.00% | +41+2,050.0% | Added |
| Wolff Wiese Magana LLC | 41 | $1.43K | 0.00% | −69−62.7% | Reduced |
| Assetmark, Inc | 32 | $1.12K | 0.00% | +32 | New |
| Avion Wealth | 54 | $1.00K | 0.00% | +54 | New |
| Raffa Wealth Management, LLC | 28 | $979 | 0.00% | 00.0% | Unchanged |
| Sachetta, LLC | 27 | $944 | 0.00% | −71−72.4% | Reduced |
| Cornerstone Planning Group LLC | 25 | $851 | 0.00% | +25 | New |
| Lee Danner & Bass Inc | 22 | $769 | 0.00% | +22 | New |
| TFC Financial Management | 21 | $735 | 0.00% | 00.0% | Unchanged |
| Front Row Advisors LLC | 20 | $699 | 0.00% | 00.0% | Unchanged |
| Key Financial Inc | 19 | $664 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 18 | $629 | 0.00% | 00.0% | Unchanged |
| Bokf, NA | 18 | $602 | 0.00% | +18 | New |
| Central Trust Co | 15 | $525 | 0.00% | +15 | New |
| Mascoma Wealth Management LLC | 14 | $489 | 0.00% | +14 | New |
| Private Wealth Management Group, LLC | 10 | $350 | 0.00% | 00.0% | Unchanged |
| WealthTrak Capital Management LLC | 10 | $350 | 0.00% | +10 | New |
| Principia Wealth Advisory, LLC | 9 | $315 | 0.00% | +9 | New |
| Rothschild Investment LLC | 5 | $175 | 0.00% | +5 | New |
| Caitong International Asset Management Co., Ltd | 3 | $105 | 0.00% | +3 | New |
| Cassady Schiller Wealth Management, LLC | 2 | $70 | 0.00% | +2 | New |
| AdvisorNet Financial, Inc | 1 | $35 | 0.00% | 00.0% | Unchanged |
| Activest Wealth Management | 1 | $35 | 0.00% | +1 | New |
| Sandy Spring Bank | 0 | $9 | 0.00% | −34−100.0% | Reduced |
| Washington Trust Advisors, Inc. | 0 | $0 | 0.00% | −83−100.0% | Sold out |
| BVF Inc | 0 | $0 | 0.00% | −1,451,879−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −750,000−100.0% | Sold out |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −500,000−100.0% | Sold out |
| First Trust Advisors LP | 0 | $0 | 0.00% | −402,300−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −235,477−100.0% | Sold out |
| Altrinsic Global Advisors LLC | 0 | $0 | 0.00% | −182,734−100.0% | Sold out |
| Peregrine Capital Management LLC | 0 | $0 | 0.00% | −131,630−100.0% | Sold out |
| Cutter Capital Management, LP | 0 | $0 | 0.00% | −97,300−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −90,017−100.0% | Sold out |
| HealthInvest Partners AB | 0 | $0 | 0.00% | −82,691−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −78,874−100.0% | Sold out |
| HBK Investments L P | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −53,479−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −45,430−100.0% | Sold out |
| Baillie Gifford & Co | 0 | $0 | 0.00% | −39,581−100.0% | Sold out |
| Polar Asset Management Partners Inc. | 0 | $0 | 0.00% | −35,400−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −30,691−100.0% | Sold out |
| Artia Global Partners LP | 0 | $0 | 0.00% | −30,479−100.0% | Sold out |
| Monashee Investment Management LLC | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Seven Eight Capital, LP | 0 | $0 | 0.00% | −17,394−100.0% | Sold out |
| Capula Management Ltd | 0 | $0 | 0.00% | −17,365−100.0% | Sold out |
| Martingale Asset Management L P | 0 | $0 | 0.00% | −12,809−100.0% | Sold out |
| Midwest Professional Planners, LTD. | 0 | $0 | 0.00% | −11,106−100.0% | Sold out |
| Susquehanna Portfolio Strategies, LLC | 0 | $0 | 0.00% | −10,894−100.0% | Sold out |
| Advent Capital Management | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Troluce Capital Advisors LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −8,940−100.0% | Sold out |
| Ariadne Wealth Management, LP | 0 | $0 | 0.00% | −9,147−100.0% | Sold out |
| Sanctuary Advisors, LLC | 0 | $0 | 0.00% | −9,277−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −6,944−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −6,328−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −6,293−100.0% | Sold out |
| HighTower Advisors, LLC | 0 | $0 | 0.00% | −5,559−100.0% | Sold out |
| O'Shaughnessy Asset Management, LLC | 0 | $0 | 0.00% | −5,273−100.0% | Sold out |
| FORA Capital, LLC | 0 | $0 | 0.00% | −5,081−100.0% | Sold out |
| GTS Securities LLC | 0 | $0 | 0.00% | −5,056−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −2,674−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −1,267−100.0% | Sold out |
| Reuter James Wealth Management, LLC | 0 | $0 | 0.00% | −1,049−100.0% | Sold out |
| Capital Performance Advisors LLP | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −700−100.0% | Sold out |
| Claris Advisors, LLC | 0 | $0 | 0.00% | −250−100.0% | Sold out |
| Allspring Global Investments Holdings, LLC | 0 | $0 | 0.00% | −237−100.0% | Sold out |