Ionis Pharmaceuticals Inc

IONS

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0000874015

SEC filings (opens in a new tab)

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

Q4 2024 vs. Q3 2024

How the institutions holding Ionis Pharmaceuticals Inc changed between Q3 2024 and Q4 2024.

All holders in Q4 2024 All holders in Q3 2024

13F holders of IONS: Q3 2024 compared with Q4 2024
Measure	Q3 2024	Of which not filed for Q4 2024	Q4 2024	Change
Holders	354	7	356	+9
Shares	157.5M	194.1K	160.5M	+3.10M (+2.0%)
Value	$6.31B	$7.77M	$5.61B	−$692.3M (−11.0%)

7 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so the changes leave them out.

New holders (58)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q4 2024 but not at the end of Q3 2024.

Institutions new to IONS in Q4 2024
Institution	Shares	Value	% of portfolio
Camber Capital Management LP	625,000	$21.9M	0.85%
Vestal Point Capital, LP	595,000	$20.8M	1.23%
Aquatic Capital Management LLC	230,016	$8.04M	0.22%
Susquehanna Fundamental Investments, LLC	213,015	$7.45M	0.12%
Verition Fund Management LLC	200,184	$7.00M	0.04%
GW&K Investment Management, LLC	187,220	$6.54M	0.06%
Sovran Advisors, LLC	171,812	$5.62M	0.80%
Woodline Partners LP	107,610	$3.76M	0.03%
Raymond James Financial Inc	105,619	$3.69M	0.00%
HSBC Holdings PLC	83,055	$2.93M	0.00%
Allostery Investments LP	65,000	$2.27M	4.46%
Exome Asset Management LLC	61,367	$2.15M	1.61%
Tema ETFs LLC	56,844	$1.99M	0.83%
Police & Firemen's Retirement System of New Jersey	56,695	$1.98M	0.02%
Fieldview Capital Management, LLC	51,282	$1.79M	0.28%
Qsemble Capital Management, LP	46,573	$1.63M	0.22%
Jump Financial, LLC	39,737	$1.39M	0.03%
KLP Kapitalforvaltning AS	29,200	$1.02M	0.00%
BlueCrest Capital Management Ltd	26,200	$916.0K	0.05%
Natixis	16,626	$581.2K	0.00%
Campbell & CO Investment Adviser LLC	15,681	$548.2K	0.04%
Prelude Capital Management, LLC	15,595	$545.2K	0.05%
Inceptionr LLC	14,390	$503.1K	0.11%
Essential Planning, LLC.	11,440	$428.1K	0.00%
Significant Wealth Partners LLC	10,905	$381.2K	0.20%
Syon Capital LLC	10,119	$353.8K	0.03%
AlphaCentric Advisors LLC	7,614	$266.2K	0.27%
Everence Capital Management Inc	6,770	$237.0K	0.02%
Silvercrest Asset Management Group LLC	6,617	$231.3K	0.00%
EntryPoint Capital, LLC	6,382	$223.1K	0.09%
Quarry LP	6,000	$209.8K	0.04%
Stevens Capital Management LP	5,860	$205.0K	0.08%
GF Fund Management Co. Ltd.	3,315	$115.9K	0.00%
Venturi Wealth Management, LLC	3,061	$107.0K	0.01%
Raiffeisen Bank International AG	1,754	$62.3K	0.00%
Union Bancaire Privee, UBP SA	265	$9.25K	0.00%
MAI Capital Management	260	$9.09K	0.00%
SBI Securities Co., Ltd.	256	$8.95K	0.00%
Newbridge Financial Services Group, Inc.	200	$6.99K	0.00%
Tidemark, LLC	200	$6.99K	0.00%
Capital Advisors, Ltd. LLC	179	$6.00K	0.00%
Golden State Wealth Management, LLC	126	$4.41K	0.00%
Transce3nd, LLC	100	$3.50K	0.00%
Orion Capital Management LLC	80	$2.80K	0.00%
Coppell Advisory Solutions LLC	51	$1.78K	0.00%
Assetmark, Inc	32	$1.12K	0.00%
Avion Wealth	54	$1.00K	0.00%
Cornerstone Planning Group LLC	25	$851	0.00%
Lee Danner & Bass Inc	22	$769	0.00%
Bokf, NA	18	$602	0.00%
Central Trust Co	15	$525	0.00%
Mascoma Wealth Management LLC	14	$489	0.00%
WealthTrak Capital Management LLC	10	$350	0.00%
Principia Wealth Advisory, LLC	9	$315	0.00%
Rothschild Investment LLC	5	$175	0.00%
Caitong International Asset Management Co., Ltd	3	$105	0.00%
Cassady Schiller Wealth Management, LLC	2	$70	0.00%
Activest Wealth Management	1	$35	0.00%

Sold out (49)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q3 2024 and filed for Q4 2024 without it.

Institutions that sold out of IONS in Q4 2024
Institution	Shares, Q3 2024	Value, Q3 2024
BVF Inc	1,451,879	$58.2M
Logos Global Management LP	750,000	$30.0M
EcoR1 Capital, LLC	500,000	$20.0M
First Trust Advisors LP	402,300	$16.1M
Twinbeech Capital LP	235,477	$9.43M
Altrinsic Global Advisors LLC	182,734	$7.32M
Peregrine Capital Management LLC	131,630	$5.27M
Cutter Capital Management, LP	97,300	$3.90M
Prudential Financial Inc	90,017	$3.61M
HealthInvest Partners AB	82,691	$3.31M
Engineers Gate Manager LP	78,874	$3.16M
HBK Investments L P	60,000	$2.40M
Tudor Investment Corp Et Al	53,479	$2.14M
Algert Global LLC	45,430	$1.82M
Baillie Gifford & Co	39,581	$1.59M
Polar Asset Management Partners Inc.	35,400	$1.42M
Capital Fund Management S.A.	30,691	$1.23M
Artia Global Partners LP	30,479	$1.22M
Monashee Investment Management LLC	20,000	$801.2K
Seven Eight Capital, LP	17,394	$696.8K
Capula Management Ltd	17,365	$695.6K
Martingale Asset Management L P	12,809	$513.1K
Midwest Professional Planners, LTD.	11,106	$444.9K
Susquehanna Portfolio Strategies, LLC	10,894	$436.4K
Advent Capital Management	10,000	$400.6K
Troluce Capital Advisors LLC	10,000	$400.6K
Two Sigma Securities, LLC	8,940	$358.1K
Ariadne Wealth Management, LP	9,147	$351.8K
Sanctuary Advisors, LLC	9,277	$315.5K
Simplex Trading, LLC	6,944	$278.0K
Acadian Asset Management LLC	6,328	$253.0K
American Century Companies Inc	6,293	$252.1K
HighTower Advisors, LLC	5,559	$223.0K
O'Shaughnessy Asset Management, LLC	5,273	$203.7K
FORA Capital, LLC	5,081	$203.5K
GTS Securities LLC	5,056	$202.5K
Quest Partners LLC	2,674	$107.1K
Quantbot Technologies LP	1,267	$50.8K
Reuter James Wealth Management, LLC	1,049	$42.0K
Capital Performance Advisors LLP	1,000	$40.1K
ADAR1 Capital Management, LLC	700	$28.0K
Claris Advisors, LLC	250	$10.0K
Allspring Global Investments Holdings, LLC	237	$9.49K
Dunhill Financial, LLC	130	$5.21K
Washington Trust Advisors, Inc.	83	$3.34K
Dynamic Wealth Strategies, LLC	80	$3.00K
Thurston, Springer, Miller, Herd & Titak, Inc.	20	$801
Rosenberg Matthew Hamilton	20	$801
Voisard Asset Management Group, Inc.	10	$401

Not filed for Q4 2024 yet (7)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q3 2024 and haven't filed a 13F for Q4 2024. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding IONS in Q3 2024 that haven't filed for Q4 2024
Institution	Shares, Q3 2024	Value, Q3 2024
Eisler Capital (US) LLC	117,565	$4.71M
Raymond James & Associates	22,524	$902.3K
Raymond James Financial Services Advisors, Inc.	14,570	$583.7K
Chartwell Investment Partners, LLC	13,759	$551.0K
PEAK6 Investments LLC	13,500	$540.8K
SpiderRock Advisors, LLC	12,036	$482.2K
Abich Financial Wealth Management LLC	131	$5.25K