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Exome Asset Management LLC

SEC CIK
0002011932
Latest filing
Aug 14, 2026

The latest 13F from Exome Asset Management LLC covers Q2 2026 (filed Aug 14, 2026): 52 long positions worth $162.1M. The top 10 holdings make up 44.6% of the portfolio, and the largest is Guardant Health, Inc. (GH) at 6.2%. Livermore has 15 filings on Form 13F from this institution, going back to Q4 2023.

What changed in Q2 2026

Share counts compared with Q1 2026: how many positions were new, added to, reduced or sold out, and the biggest buys and sells. Dollar amounts are estimated at the quarter-end prices implied by the filing.

Full comparison
New
15
Est. +$35.5M
Added
1
Est. +$781.3K
Reduced
32
Est. −$54.4M
Sold out
8
Est. −$16.1M

Top 5 holdings

Share of this quarter's portfolio value

  1. GHGuardant Health, Inc.
    6.2%$10.1MHistory
  2. PRAXPraxis Precision Medicines, Inc.
    5.6%$9.11MHistory
  3. TGTXTG Therapeutics, Inc.
    5.6%$9.06MHistory
  4. COGTCogent Biosciences, Inc.
    5.0%$8.15MHistory
  5. IONSIonis Pharmaceuticals Inc
    4.3%$6.99MHistory

Biggest buys

New and added positions, by estimated amount bought

  1. TGTXTG Therapeutics, Inc.
    +$9.06MNewHistory
  2. ABVXAbivax S.A.
    +$6.25MNewHistory
  3. QUREuniQure N.V.
    +$3.73MNewHistory
  4. AZNAstraZeneca PLC
    +$2.25MNewHistory
  5. VKTXViking Therapeutics, Inc.
    +$1.87MNewHistory

Largest weight increases

New and added positions, by percentage points of the portfolio gained

  1. TGTXTG Therapeutics, Inc.
    +5.59 pp0.0% → 5.6%History
  2. ABVXAbivax S.A.
    +3.85 pp0.0% → 3.9%History
  3. QUREuniQure N.V.
    +2.30 pp0.0% → 2.3%History
  4. AZNAstraZeneca PLC
    +1.39 pp0.0% → 1.4%History
  5. VKTXViking Therapeutics, Inc.
    +1.15 pp0.0% → 1.2%History

Biggest sells

Reduced and sold-out positions, by estimated amount sold

  1. PRAXPraxis Precision Medicines, Inc.
    −$6.11MReducedHistory
  2. ELVNEnliven Therapeutics, Inc.
    −$6.08MReducedHistory
  3. RLAYRelay Therapeutics, Inc.
    −$4.32MReducedHistory
  4. ELVElevance Health, Inc.
    −$4.30MSold outHistory
  5. CYTKCytokinetics Inc
    −$3.72MReducedHistory

Largest weight decreases

Reduced and sold-out positions, by percentage points of the portfolio lost

  1. PRAXPraxis Precision Medicines, Inc.
    −3.00 pp8.6% → 5.6%History
  2. ELVElevance Health, Inc.
    −2.53 pp2.5% → 0.0%History
  3. BBIOBridgeBio Pharma, Inc.
    −2.11 pp2.9% → 0.8%History
  4. APLSApellis Pharmaceuticals, Inc.
    −2.02 pp2.0% → 0.0%History
  5. ELVNEnliven Therapeutics, Inc.
    −1.94 pp5.1% → 3.1%History

Metrics

13F metrics for Q2 2026, computed only from the numbers in the filings. Definitions below.

Portfolio value
$162.1M
−$7.84M (−4.6%) vs. prior quarter
Positions
52
+7 vs. prior quarter
Top 10 concentration
44.6%
Top 10 as share of value
Turnover
21.8%
Q2 2026, one quarter
Average holding period
4.5 quarters
Weighted by value

How these are calculated

  • Portfolio value: the market value of all long positions in the 13F, as reported at quarter end, excluding options.
  • Top 10 concentration: the combined value of the 10 largest positions as a share of portfolio value.
  • Turnover: the smaller of this quarter's estimated purchases and estimated sales, divided by the average of this and last quarter's portfolio value. Estimates multiply the change in shares by the quarter-end price implied by the filing (market value divided by shares); new positions use this quarter's value and sold-out positions last quarter's. Only positions reported in shares count, and it is not calculated when the previous quarter was not filed.
  • Average holding period: how many consecutive quarters each current position has been held (including this one; a quarter without the position or without a filing starts the count over), weighted by this quarter's value. Counting starts with the first 13F in Livermore (Q4 2023), so positions held before then are understated.

13F filings by quarter

11 quarters, going back to Q4 2023. Bars show each quarter's 13F portfolio value; quarters without a filing are left blank.

Peak $202.4M (Q4 2025)

Q4 2023: $101.1MQ1 2024: $116.8MQ2 2024: $112.3MQ3 2024: $147.9MQ4 2024: $132.9MQ1 2025: $111.6MQ2 2025: $121.3MQ3 2025: $151.4MQ4 2025: $202.4MQ1 2026: $169.9MQ2 2026: $162.1M
Q4 2023Q2 2026
13F filings of Exome Asset Management LLC by quarter
QuarterFiledPositionsValueTop 3 holdingsChangesFiling
Q2 2026Aug 14, 202652$162.1MGHPRAXTGTXvs. Q1 2026SEC
Q1 2026May 15, 202645$169.9MPRAXCOGTELVNvs. Q4 2025SEC
Q4 2025Feb 13, 202653$202.4MPRAXCOGTGHvs. Q3 2025SEC
Q3 2025Nov 14, 202554$151.4MIONSCYTKBBIOvs. Q2 2025SEC
Q2 2025Aug 15, 2025Amended55$121.3MiShares TrBBIOGHvs. Q1 2025SEC
Q1 2025May 16, 2025Amended49$111.6MBBIOGHGERNvs. Q4 2024SEC
Q4 2024Feb 14, 202558$132.9MBBIOLLYGERNvs. Q3 2024SEC
Q3 2024Dec 13, 2024Amended59$147.9MLLYASNDBBIOvs. Q2 2024SEC
Q2 2024Oct 3, 2024Amended52$112.3MLLYSRPTONCvs. Q1 2024SEC
Q1 2024May 15, 202453$116.8MLLYRDYONCvs. Q4 2023SEC
Q4 2023Feb 15, 202452$101.1MRDYLLYIMGN–SEC