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Livermore
Livermore
ZHEN

Exome Asset Management LLC

SEC CIK
0002011932
Latest filing
Aug 14, 2026

Holdings in Q2 2025

Holdings as of Jun 30, 2025, filed Aug 15, 2025. Long positions only; changes compare share counts with Q1 2025.

Institution overview
Positions
55
+6 vs. Q1 2025
Portfolio value
$121.3M
+$9.63M (+8.6%) vs. Q1 2025
Filed
Aug 15, 2025
AmendedSEC
Holdings of Exome Asset Management LLC in Q2 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
iShares Tr464287954PUT200,000$7.35M6.1%+200,000New–
BBIOBridgeBio Pharma, Inc.COM155,533$6.72M5.5%−9,963−6.0%ReducedHistory
GHGuardant Health, Inc.COM98,182$5.11M4.2%−29,000−22.8%ReducedHistory
GERNGeron CorpCOM3,414,377$4.81M4.0%+198,920+6.2%AddedHistory
IONSIonis Pharmaceuticals IncCOM121,116$4.79M3.9%−14,500−10.7%ReducedHistory
THCTenet Healthcare CorpCOM NEW27,000$4.75M3.9%+27,000NewHistory
COGTCogent Biosciences, Inc.COM533,647$3.83M3.2%−88,031−14.2%ReducedHistory
CYTKCytokinetics IncCOM NEW115,817$3.83M3.2%+12,334+11.9%AddedHistory
REPLReplimune Group, Inc.COM397,846$3.70M3.0%+103,000+34.9%AddedHistory
LLYEli Lilly & CoStock4,673$3.64M3.0%00.0%UnchangedHistory
SLNOSoleno Therapeutics IncCOM41,641$3.49M2.9%−1,800−4.1%ReducedHistory
ISRGIntuitive Surgical IncCOM NEW6,358$3.46M2.8%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM61,356$3.25M2.7%−300−0.5%ReducedHistory
NTRANatera, Inc.COM18,650$3.15M2.6%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM444,949$3.06M2.5%−244,188−35.4%ReducedHistory
SRRKScholar Rock Holding CorpCOM84,339$2.99M2.5%00.0%UnchangedHistory
SNDXSyndax Pharmaceuticals IncCOM308,298$2.89M2.4%−28,900−8.6%ReducedHistory
VSTMVerastem, Inc.COM NEW599,900$2.49M2.1%+599,900NewHistory
PRAXPraxis Precision Medicines, Inc.COM NEW59,002$2.48M2.0%+59,002NewHistory
PENPenumbra IncCOM9,000$2.31M1.9%00.0%UnchangedHistory
ETNB89bio, Inc.COM233,426$2.29M1.9%−120,456−34.0%ReducedHistory
TVTXTravere Therapeutics, Inc.COM153,278$2.27M1.9%+35,261+29.9%AddedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS166,944$2.19M1.8%+24,200+17.0%AddedHistory
Nektar Therapeutics640268906CALL75,000$1.94M1.6%+75,000New–
WAYWaystar Holding Corp.COM46,900$1.92M1.6%+46,900NewHistory
CRBPCorbus Pharmaceuticals Holdings, Inc.COM NEW277,317$1.91M1.6%−12,373−4.3%ReducedHistory
TXG10x Genomics, Inc.CL A COM163,658$1.90M1.6%+163,658NewHistory
DYNDyne Therapeutics, Inc.COM195,933$1.87M1.5%−62,458−24.2%ReducedHistory
RGNXREGENXBIO Inc.COM226,060$1.86M1.5%−179,221−44.2%ReducedHistory
UHSUniversal Health Services IncCL B10,100$1.83M1.5%+10,100NewHistory
VERAVera Therapeutics, Inc.CL A76,700$1.81M1.5%+76,700NewHistory
CRNXCrinetics Pharmaceuticals, Inc.COM62,700$1.80M1.5%+11,405+22.2%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM98,600$1.71M1.4%+98,600NewHistory
EWTXEdgewise Therapeutics, Inc.COM124,470$1.63M1.3%+53,032+74.2%AddedHistory
Travere Therapeutics Inc89422G907CALL110,000$1.63M1.3%+110,000New–
BCRXBiocryst Pharmaceuticals IncCOM172,883$1.55M1.3%+112,283+185.3%AddedHistory
Karyopharm Therapeutics Inc.48576UAA4NOTE 3.000%10/12,000,000$1.52M1.3%00.0%Unchanged–
CLDXCelldex Therapeutics, Inc.COM NEW73,000$1.49M1.2%+73,000NewHistory
Sarepta Therapeutics, Inc.803607AD2NOTE 1.250% 9/12,000,000$1.45M1.2%+2,000,000New–
GOSSGossamer Bio, Inc.COM1,097,999$1.35M1.1%00.0%UnchangedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS53,744$1.11M0.9%−49,200−47.8%ReducedHistory
LEGNLegend Biotech CorpSPONSORED ADS29,100$1.03M0.9%+29,100NewHistory
MBXMBX Biosciences, Inc.COM63,076$719.7K0.6%−70,037−52.6%ReducedHistory
ALVOAlvotechORDINARY SHARES78,372$714.8K0.6%−11,728−13.0%ReducedHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES36,574$662.4K0.5%+36,574NewHistory
CMPSCOMPASS Pathways plcSPONSORED ADS213,544$597.9K0.5%+213,544NewHistory
ESTAEstablishment Labs Holdings Inc.COM13,100$559.5K0.5%00.0%UnchangedHistory
YARWYarrow Bioscience, Inc.COM208,970$344.8K0.3%−253,831−54.8%ReducedHistory
TILInstil Bio, Inc.COM NEW16,200$337.4K0.3%+16,200NewHistory
ANABAnaptysbio, IncCOM15,000$333.0K0.3%−101,623−87.1%ReducedHistory
ELDNEledon Pharmaceuticals, Inc.COM114,145$309.3K0.3%00.0%UnchangedHistory
LQDALiquidia CorpCOM NEW20,500$255.4K0.2%+20,500NewHistory
ABUSArbutus Biopharma CorpCOM75,484$233.2K0.2%+75,484NewHistory
ELEVElevation Acquisition Group Inc.COM110,353$40.5K<0.1%+110,353NewHistory
Mereo Biopharma Group PLC589492957PUT14,600$39.6K<0.1%+14,600New–

Options (8)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Exome Asset Management LLC in Q2 2025
SecurityClassPutsCalls
AZNAstraZeneca PLCSPONSORED ADR$3.93M–
AKROAkero Therapeutics, Inc.COM$3.13M–
ACADAcadia Pharmaceuticals IncCOM–$2.01M
CORCencora, Inc.Stock–$1.80M
Ultragenyx Pharmaceutical IN90400D908CALL–$1.36M
UNHUnitedHealth Group IncStock–$436.8K
Altimmune Inc02155H950COM NEW$414.1K–
Fulcrum Therapeutics Inc359616909CALL–$137.6K

Sold out since Q1 2025 (15)

Positions held at the end of Q1 2025 that are gone from this filing.

Positions of Exome Asset Management LLC sold out since Q1 2025
SecurityClassShares in Q1 2025Value in Q1 2025% of portfolio in Q1 2025History
AZNAstraZeneca PLCSPONSORED ADR32,534$4.73M4.2%History
AKROAkero Therapeutics, Inc.COM76,379$3.09M2.8%History
VRDNViridian Therapeutics, Inc.COM217,294$2.93M2.6%History
SVRASavara IncCOM836,397$2.32M2.1%History
GEHCGE HealthCare Technologies Inc.Stock25,400$2.05M1.8%History
IMNMImmunome Inc.COM263,841$1.78M1.6%History
ONCBeOne Medicines Ltd.ADR6,500$1.77M1.6%History
RDYDr Reddys Laboratories LtdADR117,500$1.55M1.4%History
NKTRNektar TherapeuticsCOM2,232,453$1.52M1.4%History
ARVNArvinas, Inc.COM195,295$1.37M1.2%History
TRVITrevi Therapeutics, Inc.COM163,738$1.03M0.9%History
BHVNBiohaven Ltd.COM39,900$959.2K0.9%History
AKBAAkebia Therapeutics, Inc.COM189,087$363.0K0.3%History
NUVBNuvation Bio Inc.COM CL A96,311$169.5K0.2%History
APREAprea Therapeutics, Inc.COM NEW28,972$59.1K0.1%History