Skip to main content
Livermore
Livermore
ZHEN

Exome Asset Management LLC

SEC CIK
0002011932
Latest filing
Aug 14, 2026

Holdings in Q3 2025

Holdings as of Sep 30, 2025, filed Nov 14, 2025. Long positions only; changes compare share counts with Q2 2025.

Institution overview
Positions
54
−1 vs. Q2 2025
Portfolio value
$151.4M
+$30.2M (+24.9%) vs. Q2 2025
Filed
Nov 14, 2025
SEC
Holdings of Exome Asset Management LLC in Q3 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
IONSIonis Pharmaceuticals IncCOM131,016$8.57M5.7%+9,900+8.2%AddedHistory
CYTKCytokinetics IncCOM NEW142,417$7.83M5.2%+26,600+23.0%AddedHistory
BBIOBridgeBio Pharma, Inc.COM133,087$6.91M4.6%−22,446−14.4%ReducedHistory
COGTCogent Biosciences, Inc.COM443,547$6.37M4.2%−90,100−16.9%ReducedHistory
GHGuardant Health, Inc.COM98,182$6.13M4.1%00.0%UnchangedHistory
LLYEli Lilly & CoStock7,852$5.99M4.0%+3,179+68.0%AddedHistory
NBPNovaBridge BiosciencesSPONSORED ADS1,439,604$5.44M3.6%+1,439,604NewHistory
PRAXPraxis Precision Medicines, Inc.COM NEW101,996$5.41M3.6%+42,994+72.9%AddedHistory
VERAVera Therapeutics, Inc.CL A156,072$4.54M3.0%+79,372+103.5%AddedHistory
AZNAstraZeneca PLCSPONSORED ADR28,362$4.27M2.8%+28,362NewHistory
IRONDisc Medicine, Inc.COM61,356$4.05M2.7%00.0%UnchangedHistory
ETNB89bio, Inc.COM273,661$4.02M2.7%+40,235+17.2%AddedHistory
APGEApogee Therapeutics, Inc.COM94,400$3.75M2.5%+94,400NewHistory
TVTXTravere Therapeutics, Inc.COM156,917$3.75M2.5%+3,639+2.4%AddedHistory
THCTenet Healthcare CorpCOM NEW18,100$3.68M2.4%−8,900−33.0%ReducedHistory
ARWRArrowhead Pharmaceuticals, Inc.COM104,507$3.60M2.4%+104,507NewHistory
CVSCVS Health CorpStock43,600$3.29M2.2%+43,600NewHistory
SLNOSoleno Therapeutics IncCOM48,445$3.27M2.2%+6,804+16.3%AddedHistory
NTRANatera, Inc.COM18,650$3.00M2.0%00.0%UnchangedHistory
CRBPCorbus Pharmaceuticals Holdings, Inc.COM NEW229,962$2.91M1.9%−47,355−17.1%ReducedHistory
ISRGIntuitive Surgical IncCOM NEW6,358$2.84M1.9%00.0%UnchangedHistory
EWTXEdgewise Therapeutics, Inc.COM173,439$2.81M1.9%+48,969+39.3%AddedHistory
UTHRUnited Therapeutics CorpCOM6,645$2.79M1.8%+6,645NewHistory
AKROAkero Therapeutics, Inc.COM58,579$2.78M1.8%+58,579NewHistory
IMVTImmunovant, Inc.COM158,622$2.56M1.7%+158,622NewHistory
GERNGeron CorpCOM1,858,354$2.55M1.7%−1,556,023−45.6%ReducedHistory
CTMXCytomX Therapeutics, Inc.COM745,305$2.38M1.6%+745,305NewHistory
PENPenumbra IncCOM9,000$2.28M1.5%00.0%UnchangedHistory
GKOSGLAUKOS CorpCOM27,143$2.21M1.5%+27,143NewHistory
LQDALiquidia CorpCOM NEW94,235$2.14M1.4%+73,735+359.7%AddedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS88,024$2.13M1.4%−78,920−47.3%ReducedHistory
TXG10x Genomics, Inc.CL A COM163,658$1.91M1.3%00.0%UnchangedHistory
CORCencora, Inc.Stock6,000$1.88M1.2%+6,000NewHistory
SNDXSyndax Pharmaceuticals IncCOM117,783$1.81M1.2%−190,515−61.8%ReducedHistory
WAYWaystar Holding Corp.COM46,900$1.78M1.2%00.0%UnchangedHistory
Sarepta Therapeutics, Inc.803607AD2NOTE 1.250% 9/12,000,000$1.76M1.2%00.0%Unchanged–
Karyopharm Therapeutics Inc.48576UAA4NOTE 3.000%10/12,000,000$1.63M1.1%00.0%Unchanged–
UHSUniversal Health Services IncCL B7,955$1.63M1.1%−2,145−21.2%ReducedHistory
ORICOric Pharmaceuticals, Inc.COM120,644$1.45M1.0%+120,644NewHistory
PRCTPROCEPT BioRobotics CorpCOM39,900$1.42M0.9%+39,900NewHistory
INSPInspire Medical Systems, Inc.COM18,600$1.38M0.9%+18,600NewHistory
QUREuniQure N.V.SHS22,090$1.29M0.9%+22,090NewHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD178,084$1.28M0.8%+178,084NewHistory
AVTXAvalo Therapeutics, Inc.COM NEW100,036$1.27M0.8%+100,036NewHistory
GOSSGossamer Bio, Inc.COM451,699$1.19M0.8%−646,300−58.9%ReducedHistory
ALMSAlumis Inc.COM292,770$1.17M0.8%+292,770NewHistory
UPBUpstream Bio, Inc.COM51,960$977.4K0.6%+51,960NewHistory
MBXMBX Biosciences, Inc.COM52,402$917.0K0.6%−10,674−16.9%ReducedHistory
FULCFulcrum Therapeutics, Inc.COM98,799$909.0K0.6%−346,150−77.8%ReducedHistory
ESTAEstablishment Labs Holdings Inc.COM13,100$537.0K0.4%00.0%UnchangedHistory
ABUSArbutus Biopharma CorpCOM75,484$342.7K0.2%00.0%UnchangedHistory
REPLReplimune Group, Inc.COM73,614$308.4K0.2%−324,232−81.5%ReducedHistory
VTYXVentyx Biosciences, Inc.COM60,600$188.5K0.1%+60,600NewHistory
IMUXImmunic, Inc.COM173,900$153.3K0.1%+173,900NewHistory

Options (14)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Exome Asset Management LLC in Q3 2025
SecurityClassPutsCalls
VanEck ETF Trust92189F692PHARMACEUTCL ETF–$2.71M
Travere Therapeutics Inc89422G907CALL–$2.63M
Novo-Nordisk A S670100905CALL–$1.94M
Liquidia Corporation53635D952PUT$1.21M–
Arcturus Therapeutics Hldgs03969T959PUT$921.5K–
MBX Biosciences Inc55287L951PUT$883.8K–
Cogent Biosciences Inc19240Q901CALL–$646.2K
Centessa Pharmaceuticals PLC152309950PUT$606.3K–
Praxis Precision Medicines I74006W907CALL–$530.0K
MBX Biosciences Inc55287L901CALL–$525.0K
ACADAcadia Pharmaceuticals IncCOM$426.8K–
Precigen Inc74017N955PUT$329.0K–
Karyopharm Therapeutics Inc48576U955COM NEW$314.6K–
ATYRaTYR PHARMA INCCOM NEW–$28.8K

Sold out since Q2 2025 (22)

Positions held at the end of Q2 2025 that are gone from this filing.

Positions of Exome Asset Management LLC sold out since Q2 2025
SecurityClassShares in Q2 2025Value in Q2 2025% of portfolio in Q2 2025History
iShares Tr464287954PUT200,000$7.35M6.1%–
SRRKScholar Rock Holding CorpCOM84,339$2.99M2.5%History
VSTMVerastem, Inc.COM NEW599,900$2.49M2.1%History
Nektar Therapeutics640268906CALL75,000$1.94M1.6%–
DYNDyne Therapeutics, Inc.COM195,933$1.87M1.5%History
RGNXREGENXBIO Inc.COM226,060$1.86M1.5%History
CRNXCrinetics Pharmaceuticals, Inc.COM62,700$1.80M1.5%History
APLSApellis Pharmaceuticals, Inc.COM98,600$1.71M1.4%History
Travere Therapeutics Inc89422G907CALL110,000$1.63M1.3%–
BCRXBiocryst Pharmaceuticals IncCOM172,883$1.55M1.3%History
CLDXCelldex Therapeutics, Inc.COM NEW73,000$1.49M1.2%History
GPCRStructure Therapeutics Inc.SPONSORED ADS53,744$1.11M0.9%History
LEGNLegend Biotech CorpSPONSORED ADS29,100$1.03M0.9%History
ALVOAlvotechORDINARY SHARES78,372$714.8K0.6%History
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES36,574$662.4K0.5%History
CMPSCOMPASS Pathways plcSPONSORED ADS213,544$597.9K0.5%History
YARWYarrow Bioscience, Inc.COM208,970$344.8K0.3%History
TILInstil Bio, Inc.COM NEW16,200$337.4K0.3%History
ANABAnaptysbio, IncCOM15,000$333.0K0.3%History
ELDNEledon Pharmaceuticals, Inc.COM114,145$309.3K0.3%History
ELEVElevation Acquisition Group Inc.COM110,353$40.5K<0.1%History
Mereo Biopharma Group PLC589492957PUT14,600$39.6K<0.1%–