Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 333
- −3 vs. Q4 2021
- Shares held
- 125.0M
- +1.76M (+1.4%) vs. Q4 2021
- Total value
- $4.63B
- +$876.1M (+23.4%) vs. Q4 2021
- New holders
- 47
- 107 more added
- Sold out
- 50
- 109 more reduced
5 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Tower Research Capital LLC (TRC) | 8,728 | $323.0K | 0.00% | +7,502+611.9% | Added |
| MetLife Investment Management | 8,579 | $317.8K | 0.00% | +8,579 | New |
| Tanaka Capital Management Inc | 8,547 | $317.0K | 0.64% | −315−3.6% | Reduced |
| Independent Financial Group, LLC | 8,490 | $314.5K | 0.03% | +8,490 | New |
| Brandywine Managers, LLC | 8,460 | $313.0K | 0.54% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 8,334 | $309.0K | 0.01% | +8,334 | New |
| Nicollet Investment Management, Inc. | 8,269 | $306.0K | 0.14% | −235−2.8% | Reduced |
| KBC Group NV | 8,039 | $298.0K | 0.00% | +22+0.3% | Added |
| Boston Partners | 8,037 | $298.0K | 0.00% | +247+3.2% | Added |
| Horizon Kinetics Asset Management LLC | 8,000 | $296.0K | 0.01% | 00.0% | Unchanged |
| Commerce Bank | 7,998 | $296.0K | 0.00% | +7,998 | New |
| IHT Wealth Management, LLC | 7,878 | $292.0K | 0.02% | −50−0.6% | Reduced |
| Northeast Financial Consultants Inc | 7,740 | $287.0K | 0.02% | 00.0% | Unchanged |
| Teza Capital Management LLC | 7,518 | $278.0K | 0.10% | −4,327−36.5% | Reduced |
| Martingale Asset Management L P | 7,405 | $275.0K | 0.00% | +7,405 | New |
| Utah Retirement Systems | 7,400 | $274.0K | 0.00% | −18,009−70.9% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 7,366 | $273.0K | 0.00% | +492+7.2% | Added |
| Echo Street Capital Management LLC | 7,223 | $268.0K | 0.00% | +7,223 | New |
| Bridgewater Associates, LP | 7,201 | $267.0K | 0.00% | +7,201 | New |
| Beacon Pointe Advisors, LLC | 7,055 | $261.0K | 0.00% | +7,055 | New |
| Great West Life Assurance Co | 6,605 | $260.0K | 0.00% | −438−6.2% | Reduced |
| Foundations Investment Advisors, LLC | 6,355 | $260.0K | 0.01% | +6,355 | New |
| Aristides Capital LLC | 6,891 | $255.0K | 0.17% | +6,891 | New |
| HSBC Holdings PLC | 6,597 | $242.0K | 0.00% | +6,597 | New |
| Stonegate Investment Group, LLC | 6,374 | $236.0K | 0.01% | +6,374 | New |
| Delphia (USA) Inc. | 6,216 | $230.0K | 0.17% | +6,216 | New |
| First Republic Investment Management, Inc. | 6,106 | $226.0K | 0.00% | +6,106 | New |
| FORA Capital, LLC | 6,095 | $218.0K | 0.04% | +6,095 | New |
| American Century Companies Inc | 5,594 | $207.0K | 0.00% | +5,594 | New |
| CIBC Asset Management Inc | 5,583 | $207.0K | 0.00% | +5,583 | New |
| Toroso Investments, LLC | 5,577 | $207.0K | 0.01% | +5,577 | New |
| JustInvest LLC | 5,596 | $207.0K | 0.01% | +5,596 | New |
| FDx Advisors, Inc. | 5,575 | $206.0K | 0.01% | +5,575 | New |
| Mitchell & Pahl Private Wealth, LLC | 5,489 | $203.0K | 0.13% | +5,489 | New |
| Geneos Wealth Management Inc. | 5,063 | $187.0K | 0.01% | −3−0.1% | Reduced |
| Lazard Asset Management LLC | 5,057 | $186.0K | 0.00% | −757−13.0% | Reduced |
| Beaird Harris Wealth Management, LLC | 5,000 | $185.0K | 0.07% | 00.0% | Unchanged |
| Prospera Financial Services Inc | 4,640 | $172.0K | 0.01% | +4,640 | New |
| Simplex Trading, LLC | 4,079 | $151.0K | 0.00% | +4,079 | New |
| Caldwell Trust Co | 4,000 | $148.2K | 0.02% | 00.0% | Unchanged |
| Cutler Group LP | 3,000 | $111.0K | 0.01% | −1,290−30.1% | Reduced |
| Itau Unibanco Holding S.A. | 2,791 | $103.0K | 0.00% | −13−0.5% | Reduced |
| Fifth Third Bancorp | 2,714 | $101.0K | 0.00% | +88+3.4% | Added |
| Semmax Financial Advisors Inc. | 2,574 | $95.0K | 0.04% | −201−7.2% | Reduced |
| American International Group, Inc. | 2,568 | $95.0K | 0.00% | −3−0.1% | Reduced |
| Point72 Hong Kong Ltd | 2,427 | $90.0K | 0.01% | +1,239+104.3% | Added |
| Northwestern Mutual Wealth Management Co | 2,263 | $83.0K | 0.00% | +307+15.7% | Added |
| Leonteq Securities AG | 2,227 | $82.5K | 0.00% | −4,009−64.3% | Reduced |
| Washington Trust Advisors, Inc. | 2,031 | $75.0K | 0.01% | −399−16.4% | Reduced |
| Koshinski Asset Management, Inc. | 2,013 | $74.6K | 0.01% | −31−1.5% | Reduced |
| IndexIQ Advisors LLC | 1,639 | $61.0K | 0.00% | +1,639 | New |
| CWM, LLC | 1,554 | $58.0K | 0.00% | +555+55.6% | Added |
| Twin Lakes Capital Management, LLC | 1,500 | $56.0K | 0.03% | 00.0% | Unchanged |
| Kistler-Tiffany Companies, LLC | 1,281 | $47.0K | 0.01% | 00.0% | Unchanged |
| Captrust Financial Advisors | 1,180 | $44.0K | 0.00% | −121−9.3% | Reduced |
| First Manhattan Co | 1,200 | $44.0K | 0.00% | 00.0% | Unchanged |
| Wolff Wiese Magana LLC | 1,131 | $42.0K | 0.03% | 00.0% | Unchanged |
| Riggs Asset Managment Co. Inc. | 997 | $37.0K | 0.01% | 00.0% | Unchanged |
| United Community Bank | 967 | $35.8K | 0.04% | +5+0.5% | Added |
| Archer Investment Corp | 850 | $33.7K | 0.01% | 00.0% | Unchanged |
| Bessemer Group Inc | 900 | $33.0K | 0.00% | 00.0% | Unchanged |
| Zullo Investment Group, Inc. | 817 | $30.0K | 0.02% | −69−7.8% | Reduced |
| Glassman Wealth Services | 822 | $30.0K | 0.01% | +399+94.3% | Added |
| Institutional & Family Asset Management, LLC | 746 | $28.0K | 0.00% | −19−2.5% | Reduced |
| Allworth Financial LP | 739 | $27.0K | 0.00% | +8+1.1% | Added |
| Parallel Advisors, LLC | 716 | $26.0K | 0.00% | +95+15.3% | Added |
| Heritage Wealth Management, LLC | 676 | $25.0K | 0.01% | +676 | New |
| Laurel Wealth Advisors LLC | 600 | $22.0K | 0.00% | 00.0% | Unchanged |
| AlphaMark Advisors, LLC | 555 | $21.0K | 0.01% | +375+208.3% | Added |
| Signaturefd, LLC | 541 | $20.0K | 0.00% | −135−20.0% | Reduced |
| Ellis Investment Partners, LLC | 563 | $20.0K | 0.00% | 00.0% | Unchanged |
| Patriot Financial Group Insurance Agency, LLC | 499 | $18.0K | 0.00% | +5+1.0% | Added |
| Riverview Trust Co | 476 | $18.0K | 0.01% | +476 | New |
| Daiwa Securities Group Inc. | 412 | $15.0K | 0.00% | 00.0% | Unchanged |
| Whittier Trust Co of Nevada Inc | 405 | $15.0K | 0.00% | 00.0% | Unchanged |
| Global Trust Asset Management, LLC | 399 | $15.0K | 0.01% | 00.0% | Unchanged |
| Banque Cantonale Vaudoise | 400 | $15.0K | 0.00% | 00.0% | Unchanged |
| Spire Wealth Management | 369 | $14.0K | 0.00% | −2,121−85.2% | Reduced |
| Covestor Ltd | 377 | $14.0K | 0.01% | +345+1,078.1% | Added |
| Steward Partners Investment Advisory, LLC | 362 | $13.0K | 0.00% | −343−48.7% | Reduced |
| Nisa Investment Advisors, LLC | 359 | $13.0K | 0.00% | 00.0% | Unchanged |
| Elequin Capital LP | 360 | $13.0K | 0.00% | +360 | New |
| American Portfolios Advisors | 300 | $11.1K | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 267 | $10.0K | 0.00% | −73−21.5% | Reduced |
| Hall Laurie J Trustee | 270 | $10.0K | 0.00% | 00.0% | Unchanged |
| Gables Capital Management Inc. | 275 | $10.0K | 0.01% | 00.0% | Unchanged |
| Proequities, Inc. | 214 | $8.00K | 0.00% | +11+5.4% | Added |
| Clearstead Advisors, LLC | 185 | $7.00K | 0.00% | 00.0% | Unchanged |
| AllSquare Wealth Management LLC | 198 | $7.00K | 0.00% | 00.0% | Unchanged |
| Insight Financial Services | 200 | $7.00K | 0.01% | 00.0% | Unchanged |
| Carolinas Wealth Consulting LLC | 187 | $7.00K | 0.00% | 00.0% | Unchanged |
| Meeder Asset Management Inc | 186 | $7.00K | 0.00% | +186 | New |
| Concord Wealth Partners | 153 | $6.00K | 0.00% | −300−66.2% | Reduced |
| Pacifica Partners Inc. | 150 | $5.00K | 0.00% | 00.0% | Unchanged |
| Umb Bank N A | 142 | $5.00K | 0.00% | 00.0% | Unchanged |
| Benjamin F. Edwards & Company, Inc. | 119 | $4.00K | 0.00% | 00.0% | Unchanged |
| GPS Wealth Strategies Group, LLC | 119 | $4.00K | 0.00% | 00.0% | Unchanged |
| Monolith Advisors | 133 | $4.00K | 0.00% | 00.0% | Unchanged |
| McCarthy Asset Management, Inc. | 110 | $4.00K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 100 | $3.88K | 0.00% | 00.0% | Unchanged |