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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 3 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

Q1 2022 vs. Q4 2021

How the institutions holding Ionis Pharmaceuticals Inc changed between Q4 2021 and Q1 2022.

All holders in Q1 2022All holders in Q4 2021

13F holders of IONS: Q4 2021 compared with Q1 2022
MeasureQ4 2021Of which not filed for Q1 2022Q1 2022Change
Holders3415333−3
Shares123.2M5.27K125.0M+1.76M (+1.4%)
Value$3.75B$160.0K$4.63B+$876.1M (+23.4%)

5 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so the changes leave them out.

New holders (47)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q1 2022 but not at the end of Q4 2021.

Institutions new to IONS in Q1 2022
InstitutionSharesValue% of portfolio
Tweedy, Browne Co LLC2,925,102$108.3M3.50%
Tang Capital Management LLC200,000$7.41M1.50%
HRT Financial LP109,376$4.05M0.03%
Manufacturers Life Insurance Company, The75,298$2.69M0.00%
Schonfeld Strategic Advisors LLC55,543$2.06M0.02%
Gotham Asset Management, LLC38,427$1.42M0.04%
Amalgamated Financial Corp.31,934$1.18M0.01%
Strategic Wealth Advisors Group, LLC21,484$813.0K0.03%
Global Retirement Partners, LLC20,341$755.0K0.06%
Weiss Asset Management LP18,145$672.0K0.02%
Bradley Foster & Sargent Inc17,050$632.0K0.01%
Seven Eight Capital, LP15,796$585.0K0.08%
Y-Intercept (Hong Kong) Ltd10,689$396.0K0.09%
Pearl River Capital, LLC10,153$376.0K0.10%
Corton Capital Inc.8,809$326.0K0.14%
MetLife Investment Management8,579$317.8K0.00%
Independent Financial Group, LLC8,490$314.5K0.03%
E Fund Management Co., Ltd.8,334$309.0K0.01%
Commerce Bank7,998$296.0K0.00%
Martingale Asset Management L P7,405$275.0K0.00%
Echo Street Capital Management LLC7,223$268.0K0.00%
Bridgewater Associates, LP7,201$267.0K0.00%
Beacon Pointe Advisors, LLC7,055$261.0K0.00%
Foundations Investment Advisors, LLC6,355$260.0K0.01%
Aristides Capital LLC6,891$255.0K0.17%
HSBC Holdings PLC6,597$242.0K0.00%
Stonegate Investment Group, LLC6,374$236.0K0.01%
Delphia (USA) Inc.6,216$230.0K0.17%
First Republic Investment Management, Inc.6,106$226.0K0.00%
FORA Capital, LLC6,095$218.0K0.04%
American Century Companies Inc5,594$207.0K0.00%
CIBC Asset Management Inc5,583$207.0K0.00%
Toroso Investments, LLC5,577$207.0K0.01%
JustInvest LLC5,596$207.0K0.01%
FDx Advisors, Inc.5,575$206.0K0.01%
Mitchell & Pahl Private Wealth, LLC5,489$203.0K0.13%
Prospera Financial Services Inc4,640$172.0K0.01%
Simplex Trading, LLC4,079$151.0K0.00%
IndexIQ Advisors LLC1,639$61.0K0.00%
Heritage Wealth Management, LLC676$25.0K0.01%
Riverview Trust Co476$18.0K0.01%
Elequin Capital LP360$13.0K0.00%
Meeder Asset Management Inc186$7.00K0.00%
Raleigh Capital Management Inc.72$3.00K0.00%
TCWP LLC38$1.00K0.00%
Retirement Group, LLC11$00.00%
Hexagon Capital Partners LLC9$00.00%

Sold out (50)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q4 2021 and filed for Q1 2022 without it.

Institutions that sold out of IONS in Q1 2022
InstitutionShares, Q4 2021Value, Q4 2021
Bank of Nova Scotia601,883$18.3M
Natixis300,797$9.15M
MUFG Securities EMEA plc200,000$6.09M
Balyasny Asset Management LLC193,120$5.88M
D. E. Shaw & Co., Inc.160,659$4.89M
Wolverine Trading, LLC108,529$3.31M
Parkman Healthcare Partners LLC80,238$2.44M
National Bank of Canada70,000$2.13M
Point72 Asset Management, L.P.53,981$1.64M
Alpha DNA Investment Management LLC50,614$1.54M
Pura Vida Investments, LLC48,544$1.48M
Jefferies Group LLC44,000$1.34M
Group One Trading, L.P.36,268$1.10M
Healthcare of Ontario Pension Plan Trust Fund34,069$1.04M
Occudo Quantitative Strategies LP26,650$811.0K
AE Wealth Management LLC26,085$794.0K
ExodusPoint Capital Management, LP19,788$602.0K
Quantamental Technologies LLC17,671$538.0K
Campbell & CO Investment Adviser LLC17,346$528.0K
Verition Fund Management LLC13,740$418.0K
Gsa Capital Partners LLP13,368$407.0K
Wellington Management Group LLP13,134$399.0K
Caption Management, LLC12,000$366.0K
Dynamic Technology Lab Private Ltd11,134$339.0K
Greenup Street Wealth Management LLC11,145$339.0K
Walleye Trading LLC10,695$325.0K
Brookfield Asset Management Inc.9,638$293.0K
Metropolitan Life Insurance Co8,813$268.2K
Virginia Retirement Systems Et Al7,200$219.0K
Quantbot Technologies LP5,076$154.0K
NuWave Investment Management, LLC3,762$114.0K
Macroview Investment Management LLC616$19.0K
FSB Premier Wealth Management, Inc.482$14.0K
Confluence Wealth Services, Inc.384$11.0K
Heritage Wealth Advisors334$10.0K
Jones Financial Companies LLLP300$9.00K
Amplius Wealth Advisors, LLC300$9.00K
Logan Capital Management Inc178$5.00K
Pinnacle Bancorp, Inc.179$5.00K
Cornerstone Advisory, LLC100$3.00K
SkyView Investment Advisors, LLC91$3.00K
CoreCap Advisors, LLC102$3.00K
Motley Fool Asset Management LLC66$2.00K
SRS Capital Advisors, Inc.38$1.00K
Signet Financial Management, LLC48$1.00K
Bedel Financial Consulting, Inc.38$1.00K
Sound Income Strategies, LLC20$1.00K
Private Capital Group, LLC31$1.00K
KB Financial Partners, LLC34$1.00K
Gemmer Asset Management LLC3$0

Not filed for Q1 2022 yet (5)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q4 2021 and haven't filed a 13F for Q1 2022. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding IONS in Q4 2021 that haven't filed for Q1 2022
InstitutionShares, Q4 2021Value, Q4 2021
NEXT Financial Group, Inc2,893$88.0K
Harbour Investments, Inc.1,260$38.0K
Carroll Financial Associates, Inc.793$24.0K
Reilly Financial Advisors, LLC220$7.00K
Bell Investment Advisors, Inc102$3.00K