Skip to main content
Livermore
Livermore
ZHEN

Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2022

Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
333
−3 vs. Q4 2021
Shares held
125.0M
+1.76M (+1.4%) vs. Q4 2021
Total value
$4.63B
+$876.1M (+23.4%) vs. Q4 2021
New holders
47
107 more added
Sold out
50
109 more reduced

5 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 333 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ1 2022: $4.63B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2021.

Institutions holding IONS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Gradient Investments LLC91$3.00K0.00%−186−67.1%Reduced
Centerpoint Advisors, LLC68$3.00K0.00%00.0%Unchanged
Global Wealth Management Investment Advisory, Inc.80$3.00K0.00%00.0%Unchanged
Versant Capital Management, Inc78$3.00K0.00%+32+69.6%Added
Raleigh Capital Management Inc.72$3.00K0.00%+72New
Rockbridge Investment Management, LCC58$2.26K0.00%00.0%Unchanged
Parkside Financial Bank & Trust62$2.00K0.00%00.0%Unchanged
Blume Capital Management, Inc.55$2.00K0.00%00.0%Unchanged
Trustcore Financial Services, LLC58$2.00K0.00%00.0%Unchanged
Earnest Partners LLC49$2.00K0.00%00.0%Unchanged
Massmutual Trust Co FSB48$2.00K0.00%+26+118.2%Added
Sargent Bickham Lagudis LLC43$2.00K0.00%00.0%Unchanged
Lindbrook Capital, LLC57$2.00K0.00%+37+185.0%Added
Dark Forest Capital Management LP49$2.00K0.00%+46+1,533.3%Added
Kelly Financial Services LLC30$1.11K0.00%00.0%Unchanged
Raffa Wealth Management, LLC28$1.04K0.00%00.0%Unchanged
Orion Capital Management LLC38$1.00K0.00%−500−92.9%Reduced
Bogart Wealth, LLC30$1.00K0.00%−70−70.0%Reduced
AdvisorNet Financial, Inc29$1.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.35$1.00K0.00%00.0%Unchanged
Cranbrook Wealth Management, LLC25$1.00K0.00%00.0%Unchanged
BDO Wealth Advisors, LLC33$1.00K0.00%00.0%Unchanged
Key Financial Inc19$1.00K0.00%00.0%Unchanged
FourThought Financial, LLC27$1.00K0.00%00.0%Unchanged
Focused Wealth Management, Inc16$1.00K0.00%00.0%Unchanged
First Bank & Trust15$1.00K0.00%00.0%Unchanged
TCWP LLC38$1.00K0.00%+38New
Huntington National Bank1$00.00%00.0%Unchanged
Valley National Advisers Inc11$00.00%00.0%Unchanged
Ci Investments Inc.8$00.00%00.0%Unchanged
Aspire Private Capital, LLC8$00.00%00.0%Unchanged
Retirement Group, LLC11$00.00%+11New
Hexagon Capital Partners LLC9$00.00%+9New
Bank of Nova Scotia0$00.00%−601,883−100.0%Sold out
Natixis0$00.00%−300,797−100.0%Sold out
MUFG Securities EMEA plc0$00.00%−200,000−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−193,120−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−160,659−100.0%Sold out
Wolverine Trading, LLC0$00.00%−108,529−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−80,238−100.0%Sold out
National Bank of Canada0$00.00%−70,000−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−53,981−100.0%Sold out
Alpha DNA Investment Management LLC0$00.00%−50,614−100.0%Sold out
Pura Vida Investments, LLC0$00.00%−48,544−100.0%Sold out
Jefferies Group LLC0$00.00%−44,000−100.0%Sold out
Group One Trading, L.P.0$00.00%−36,268−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−34,069−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−26,650−100.0%Sold out
AE Wealth Management LLC0$00.00%−26,085−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−19,788−100.0%Sold out
Quantamental Technologies LLC0$00.00%−17,671−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−17,346−100.0%Sold out
Verition Fund Management LLC0$00.00%−13,740−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−13,368−100.0%Sold out
Wellington Management Group LLP0$00.00%−13,134−100.0%Sold out
Caption Management, LLC0$00.00%−12,000−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−11,134−100.0%Sold out
Greenup Street Wealth Management LLC0$00.00%−11,145−100.0%Sold out
Walleye Trading LLC0$00.00%−10,695−100.0%Sold out
Brookfield Asset Management Inc.0$00.00%−9,638−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−8,813−100.0%Sold out
Virginia Retirement Systems Et Al0$00.00%−7,200−100.0%Sold out
Quantbot Technologies LP0$00.00%−5,076−100.0%Sold out
NuWave Investment Management, LLC0$00.00%−3,762−100.0%Sold out
Macroview Investment Management LLC0$00.00%−616−100.0%Sold out
FSB Premier Wealth Management, Inc.0$00.00%−482−100.0%Sold out
Confluence Wealth Services, Inc.0$00.00%−384−100.0%Sold out
Heritage Wealth Advisors0$00.00%−334−100.0%Sold out
Jones Financial Companies LLLP0$00.00%−300−100.0%Sold out
Amplius Wealth Advisors, LLC0$00.00%−300−100.0%Sold out
Logan Capital Management Inc0$00.00%−178−100.0%Sold out
Pinnacle Bancorp, Inc.0$00.00%−179−100.0%Sold out
Cornerstone Advisory, LLC0$00.00%−100−100.0%Sold out
SkyView Investment Advisors, LLC0$00.00%−91−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−102−100.0%Sold out
Motley Fool Asset Management LLC0$00.00%−66−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−38−100.0%Sold out
Signet Financial Management, LLC0$00.00%−48−100.0%Sold out
Bedel Financial Consulting, Inc.0$00.00%−38−100.0%Sold out
Sound Income Strategies, LLC0$00.00%−20−100.0%Sold out
Private Capital Group, LLC0$00.00%−31−100.0%Sold out
KB Financial Partners, LLC0$00.00%−34−100.0%Sold out
Gemmer Asset Management LLC0$00.00%−3−100.0%Sold out
NEXT Financial Group, Inc––––Not filed
Harbour Investments, Inc.––––Not filed
Carroll Financial Associates, Inc.––––Not filed
Reilly Financial Advisors, LLC––––Not filed
Bell Investment Advisors, Inc––––Not filed