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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2022

Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
333
−3 vs. Q4 2021
Shares held
125.0M
+1.76M (+1.4%) vs. Q4 2021
Total value
$4.63B
+$876.1M (+23.4%) vs. Q4 2021
New holders
47
107 more added
Sold out
50
109 more reduced

5 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 333 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ1 2022: $4.63B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2021.

Institutions holding IONS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Huntington National Bank1$00.00%00.0%Unchanged
Valley National Advisers Inc11$00.00%00.0%Unchanged
Ci Investments Inc.8$00.00%00.0%Unchanged
Aspire Private Capital, LLC8$00.00%00.0%Unchanged
Retirement Group, LLC11$00.00%+11New
Hexagon Capital Partners LLC9$00.00%+9New
Orion Capital Management LLC38$1.00K0.00%−500−92.9%Reduced
Bogart Wealth, LLC30$1.00K0.00%−70−70.0%Reduced
AdvisorNet Financial, Inc29$1.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.35$1.00K0.00%00.0%Unchanged
Cranbrook Wealth Management, LLC25$1.00K0.00%00.0%Unchanged
BDO Wealth Advisors, LLC33$1.00K0.00%00.0%Unchanged
Key Financial Inc19$1.00K0.00%00.0%Unchanged
FourThought Financial, LLC27$1.00K0.00%00.0%Unchanged
Focused Wealth Management, Inc16$1.00K0.00%00.0%Unchanged
First Bank & Trust15$1.00K0.00%00.0%Unchanged
TCWP LLC38$1.00K0.00%+38New
Raffa Wealth Management, LLC28$1.04K0.00%00.0%Unchanged
Kelly Financial Services LLC30$1.11K0.00%00.0%Unchanged
Parkside Financial Bank & Trust62$2.00K0.00%00.0%Unchanged
Blume Capital Management, Inc.55$2.00K0.00%00.0%Unchanged
Trustcore Financial Services, LLC58$2.00K0.00%00.0%Unchanged
Earnest Partners LLC49$2.00K0.00%00.0%Unchanged
Massmutual Trust Co FSB48$2.00K0.00%+26+118.2%Added
Sargent Bickham Lagudis LLC43$2.00K0.00%00.0%Unchanged
Lindbrook Capital, LLC57$2.00K0.00%+37+185.0%Added
Dark Forest Capital Management LP49$2.00K0.00%+46+1,533.3%Added
Rockbridge Investment Management, LCC58$2.26K0.00%00.0%Unchanged
Gradient Investments LLC91$3.00K0.00%−186−67.1%Reduced
Centerpoint Advisors, LLC68$3.00K0.00%00.0%Unchanged
Global Wealth Management Investment Advisory, Inc.80$3.00K0.00%00.0%Unchanged
Versant Capital Management, Inc78$3.00K0.00%+32+69.6%Added
Raleigh Capital Management Inc.72$3.00K0.00%+72New
TD Waterhouse Canada Inc.100$3.88K0.00%00.0%Unchanged
Benjamin F. Edwards & Company, Inc.119$4.00K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC119$4.00K0.00%00.0%Unchanged
Monolith Advisors133$4.00K0.00%00.0%Unchanged
McCarthy Asset Management, Inc.110$4.00K0.00%00.0%Unchanged
Pacifica Partners Inc.150$5.00K0.00%00.0%Unchanged
Umb Bank N A142$5.00K0.00%00.0%Unchanged
Concord Wealth Partners153$6.00K0.00%−300−66.2%Reduced
Clearstead Advisors, LLC185$7.00K0.00%00.0%Unchanged
AllSquare Wealth Management LLC198$7.00K0.00%00.0%Unchanged
Insight Financial Services200$7.00K0.01%00.0%Unchanged
Carolinas Wealth Consulting LLC187$7.00K0.00%00.0%Unchanged
Meeder Asset Management Inc186$7.00K0.00%+186New
Proequities, Inc.214$8.00K0.00%+11+5.4%Added
Quadrant Capital Group LLC267$10.0K0.00%−73−21.5%Reduced
Hall Laurie J Trustee270$10.0K0.00%00.0%Unchanged
Gables Capital Management Inc.275$10.0K0.01%00.0%Unchanged
American Portfolios Advisors300$11.1K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC362$13.0K0.00%−343−48.7%Reduced
Nisa Investment Advisors, LLC359$13.0K0.00%00.0%Unchanged
Elequin Capital LP360$13.0K0.00%+360New
Spire Wealth Management369$14.0K0.00%−2,121−85.2%Reduced
Covestor Ltd377$14.0K0.01%+345+1,078.1%Added
Daiwa Securities Group Inc.412$15.0K0.00%00.0%Unchanged
Whittier Trust Co of Nevada Inc405$15.0K0.00%00.0%Unchanged
Global Trust Asset Management, LLC399$15.0K0.01%00.0%Unchanged
Banque Cantonale Vaudoise400$15.0K0.00%00.0%Unchanged
Patriot Financial Group Insurance Agency, LLC499$18.0K0.00%+5+1.0%Added
Riverview Trust Co476$18.0K0.01%+476New
Signaturefd, LLC541$20.0K0.00%−135−20.0%Reduced
Ellis Investment Partners, LLC563$20.0K0.00%00.0%Unchanged
AlphaMark Advisors, LLC555$21.0K0.01%+375+208.3%Added
Laurel Wealth Advisors LLC600$22.0K0.00%00.0%Unchanged
Heritage Wealth Management, LLC676$25.0K0.01%+676New
Parallel Advisors, LLC716$26.0K0.00%+95+15.3%Added
Allworth Financial LP739$27.0K0.00%+8+1.1%Added
Institutional & Family Asset Management, LLC746$28.0K0.00%−19−2.5%Reduced
Zullo Investment Group, Inc.817$30.0K0.02%−69−7.8%Reduced
Glassman Wealth Services822$30.0K0.01%+399+94.3%Added
Bessemer Group Inc900$33.0K0.00%00.0%Unchanged
Archer Investment Corp850$33.7K0.01%00.0%Unchanged
United Community Bank967$35.8K0.04%+5+0.5%Added
Riggs Asset Managment Co. Inc.997$37.0K0.01%00.0%Unchanged
Wolff Wiese Magana LLC1,131$42.0K0.03%00.0%Unchanged
Captrust Financial Advisors1,180$44.0K0.00%−121−9.3%Reduced
First Manhattan Co1,200$44.0K0.00%00.0%Unchanged
Kistler-Tiffany Companies, LLC1,281$47.0K0.01%00.0%Unchanged
Twin Lakes Capital Management, LLC1,500$56.0K0.03%00.0%Unchanged
CWM, LLC1,554$58.0K0.00%+555+55.6%Added
IndexIQ Advisors LLC1,639$61.0K0.00%+1,639New
Koshinski Asset Management, Inc.2,013$74.6K0.01%−31−1.5%Reduced
Washington Trust Advisors, Inc.2,031$75.0K0.01%−399−16.4%Reduced
Leonteq Securities AG2,227$82.5K0.00%−4,009−64.3%Reduced
Northwestern Mutual Wealth Management Co2,263$83.0K0.00%+307+15.7%Added
Point72 Hong Kong Ltd2,427$90.0K0.01%+1,239+104.3%Added
Semmax Financial Advisors Inc.2,574$95.0K0.04%−201−7.2%Reduced
American International Group, Inc.2,568$95.0K0.00%−3−0.1%Reduced
Fifth Third Bancorp2,714$101.0K0.00%+88+3.4%Added
Itau Unibanco Holding S.A.2,791$103.0K0.00%−13−0.5%Reduced
Cutler Group LP3,000$111.0K0.01%−1,290−30.1%Reduced
Caldwell Trust Co4,000$148.2K0.02%00.0%Unchanged
Simplex Trading, LLC4,079$151.0K0.00%+4,079New
Prospera Financial Services Inc4,640$172.0K0.01%+4,640New
Beaird Harris Wealth Management, LLC5,000$185.0K0.07%00.0%Unchanged
Lazard Asset Management LLC5,057$186.0K0.00%−757−13.0%Reduced
Geneos Wealth Management Inc.5,063$187.0K0.01%−3−0.1%Reduced
Mitchell & Pahl Private Wealth, LLC5,489$203.0K0.13%+5,489New