Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 333
- −3 vs. Q4 2021
- Shares held
- 125.0M
- +1.76M (+1.4%) vs. Q4 2021
- Total value
- $4.63B
- +$876.1M (+23.4%) vs. Q4 2021
- New holders
- 47
- 107 more added
- Sold out
- 50
- 109 more reduced
5 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Manufacturers Life Insurance Company, The | 75,298 | $2.69M | 0.00% | +75,298 | New |
| Rhenman & Partners Asset Management AB | 71,000 | $2.63M | 0.26% | −4,000−5.3% | Reduced |
| Guggenheim Capital LLC | 68,237 | $2.53M | 0.02% | −4,741−6.5% | Reduced |
| Voya Investment Management LLC | 64,265 | $2.38M | 0.00% | −1,243−1.9% | Reduced |
| Alliancebernstein L.P. | 61,939 | $2.29M | 0.00% | −41,275−40.0% | Reduced |
| AlphaCrest Capital Management LLC | 58,292 | $2.16M | 0.12% | +5,385+10.2% | Added |
| Eaton Vance Management | 56,565 | $2.10M | 0.00% | +28,873+104.3% | Added |
| Schonfeld Strategic Advisors LLC | 55,543 | $2.06M | 0.02% | +55,543 | New |
| Treasurer of the State of North Carolina | 51,671 | $1.91M | 0.01% | +825+1.6% | Added |
| Raymond James Financial Services Advisors, Inc. | 50,585 | $1.87M | 0.00% | +1,604+3.3% | Added |
| Susquehanna International Group, LLP | 49,726 | $1.84M | 0.00% | −154,529−75.7% | Reduced |
| Erste Asset Management GmbH | 51,300 | $1.83M | 0.03% | 00.0% | Unchanged |
| Trexquant Investment LP | 47,762 | $1.77M | 0.08% | +13,859+40.9% | Added |
| Capital Fund Management S.A. | 44,719 | $1.66M | 0.04% | +16,611+59.1% | Added |
| Koss-Olinger Consulting, LLC | 44,120 | $1.63M | 0.26% | +14,959+51.3% | Added |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.55M | 0.21% | 00.0% | Unchanged |
| Capital Counsel LLC | 41,010 | $1.52M | 0.07% | +430+1.1% | Added |
| Janney Montgomery Scott LLC | 38,614 | $1.43M | 0.01% | +2,190+6.0% | Added |
| Gotham Asset Management, LLC | 38,427 | $1.42M | 0.04% | +38,427 | New |
| Ergoteles LLC | 38,000 | $1.41M | 0.05% | +30,045+377.7% | Added |
| Arizona State Retirement System | 34,354 | $1.27M | 0.01% | +164+0.5% | Added |
| Deutsche Bank AG | 33,362 | $1.24M | 0.00% | +19,275+136.8% | Added |
| Employees Retirement System of Texas | 32,409 | $1.20M | 0.01% | 00.0% | Unchanged |
| Macquarie Group Ltd | 32,006 | $1.19M | 0.00% | −543−1.7% | Reduced |
| Amalgamated Bank | 31,934 | $1.18M | 0.01% | +2,610+8.9% | Added |
| Amalgamated Financial Corp. | 31,934 | $1.18M | 0.01% | +31,934 | New |
| Truist Financial Corp | 31,270 | $1.16M | 0.00% | +333+1.1% | Added |
| Principal Financial Group Inc | 30,211 | $1.12M | 0.00% | −1,544−4.9% | Reduced |
| Tudor Investment Corp Et Al | 29,525 | $1.09M | 0.03% | −148,861−83.4% | Reduced |
| First Foundation Advisors | 29,130 | $1.08M | 0.04% | +1,158+4.1% | Added |
| MML Investors Services, LLC | 28,122 | $1.04M | 0.01% | +2,905+11.5% | Added |
| Grandfield & Dodd, LLC | 28,001 | $1.04M | 0.07% | +1,230+4.6% | Added |
| Jane Street Group, LLC | 27,791 | $1.03M | 0.00% | −24,759−47.1% | Reduced |
| Teacher Retirement System of Texas | 26,212 | $971.0K | 0.00% | +1,758+7.2% | Added |
| Commonwealth Equity Services, LLC | 25,993 | $962.0K | 0.00% | −2,773−9.6% | Reduced |
| Janus Henderson Group PLC | 25,723 | $953.0K | 0.00% | +70.0% | Added |
| Ensign Peak Advisors, Inc | 24,870 | $921.0K | 0.00% | −3,460−12.2% | Reduced |
| Brookstone Capital Management | 22,371 | $886.0K | 0.02% | +8,424+60.4% | Added |
| Kestra Advisory Services, LLC | 23,617 | $875.0K | 0.01% | +3,936+20.0% | Added |
| Storebrand Asset Management AS | 22,462 | $832.0K | 0.00% | 00.0% | Unchanged |
| Strategic Wealth Advisors Group, LLC | 21,484 | $813.0K | 0.03% | +21,484 | New |
| US Bancorp | 21,458 | $795.0K | 0.00% | +2,343+12.3% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $773.0K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 20,341 | $755.0K | 0.06% | +20,341 | New |
| Graham Capital Management, L.P. | 20,100 | $744.0K | 0.03% | +13,296+195.4% | Added |
| Advisor Group Holdings, Inc. | 19,566 | $728.0K | 0.00% | +419+2.2% | Added |
| Public Employees Retirement Association of Colorado | 19,604 | $726.0K | 0.00% | 00.0% | Unchanged |
| Vestmark Advisory Solutions, Inc. | 19,161 | $710.0K | 0.04% | +583+3.1% | Added |
| Squarepoint Ops LLC | 18,894 | $700.0K | 0.01% | −42,446−69.2% | Reduced |
| Federated Hermes, Inc. | 18,362 | $680.0K | 0.00% | +14,109+331.7% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,248 | $676.0K | 0.00% | −3,873−17.5% | Reduced |
| Weiss Asset Management LP | 18,145 | $672.0K | 0.02% | +18,145 | New |
| ProShare Advisors LLC | 17,901 | $663.0K | 0.00% | −5,531−23.6% | Reduced |
| Profund Advisors LLC | 17,592 | $652.0K | 0.03% | −1,825−9.4% | Reduced |
| Castle Rock Wealth Management, LLC | 15,593 | $639.0K | 0.29% | 00.0% | Unchanged |
| Bradley Foster & Sargent Inc | 17,050 | $632.0K | 0.01% | +17,050 | New |
| Oppenheimer & Co Inc | 16,560 | $613.0K | 0.01% | −1,798−9.8% | Reduced |
| Cetera Advisor Networks LLC | 15,981 | $592.0K | 0.01% | +3,156+24.6% | Added |
| Natixis Advisors, L.P. | 15,861 | $587.0K | 0.00% | −34−0.2% | Reduced |
| Seven Eight Capital, LP | 15,796 | $585.0K | 0.08% | +15,796 | New |
| Xponance, Inc. | 14,898 | $552.0K | 0.01% | +8+0.1% | Added |
| SG3 Management, LLC | 14,780 | $547.0K | 0.15% | +6,280+73.9% | Added |
| Blair William & Co | 14,728 | $546.0K | 0.00% | +264+1.8% | Added |
| Vontobel Holding Ltd. | 14,715 | $545.0K | 0.00% | +3,405+30.1% | Added |
| Handelsbanken Fonder AB | 13,711 | $508.0K | 0.00% | −10,700−43.8% | Reduced |
| North Star Asset Management Inc | 13,680 | $507.0K | 0.03% | 00.0% | Unchanged |
| Comerica Bank | 11,755 | $506.0K | 0.00% | 00.0% | Unchanged |
| Algert Global LLC | 13,344 | $494.0K | 0.03% | −25,086−65.3% | Reduced |
| Lincoln National Corp | 13,261 | $491.0K | 0.01% | −809−5.7% | Reduced |
| Cowen and Company, LLC | 13,257 | $491.0K | 0.05% | +5,527+71.5% | Added |
| Creative Planning | 12,758 | $472.0K | 0.00% | −2,358−15.6% | Reduced |
| Ameriprise Financial Inc | 12,682 | $467.0K | 0.00% | +3,055+31.7% | Added |
| Stephens Inc | 12,552 | $465.0K | 0.01% | −5,149−29.1% | Reduced |
| Arden Trust Co | 12,318 | $456.0K | 0.09% | −3,236−20.8% | Reduced |
| Virtus ETF Advisers LLC | 12,296 | $455.0K | 0.20% | 00.0% | Unchanged |
| IFP Advisors, Inc | 9,162 | $445.0K | 0.01% | +6,489+242.8% | Added |
| Victory Capital Management Inc | 11,825 | $435.0K | 0.00% | −1,322−10.1% | Reduced |
| SG Americas Securities, LLC | 11,591 | $429.0K | 0.00% | −1,341−10.4% | Reduced |
| Rockefeller Capital Management L.P. | 11,256 | $416.0K | 0.00% | −836−6.9% | Reduced |
| Plancorp, LLC | 11,212 | $415.0K | 0.03% | −62−0.5% | Reduced |
| Shell Asset Management Co | 11,022 | $408.0K | 0.01% | −1,629−12.9% | Reduced |
| SEI Investments Co | 11,018 | $407.0K | 0.00% | −176−1.6% | Reduced |
| Oppenheimer Asset Management Inc. | 10,995 | $407.0K | 0.01% | +1,213+12.4% | Added |
| Y-Intercept (Hong Kong) Ltd | 10,689 | $396.0K | 0.09% | +10,689 | New |
| Cambridge Investment Research Advisors, Inc. | 10,467 | $388.0K | 0.00% | +20+0.2% | Added |
| Baird Financial Group, Inc. | 10,293 | $381.0K | 0.00% | −1,063−9.4% | Reduced |
| Pearl River Capital, LLC | 10,153 | $376.0K | 0.10% | +10,153 | New |
| Brown Advisory Securities, LLC | 10,000 | $370.0K | 0.22% | −3,000−23.1% | Reduced |
| Maryland State Retirement & Pension System | 9,956 | $369.0K | 0.01% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 9,868 | $366.0K | 0.01% | −24,512−71.3% | Reduced |
| Kennedy Capital Management, Inc. | 9,848 | $365.0K | 0.01% | +2,315+30.7% | Added |
| Berkshire Asset Management LLC | 9,739 | $361.0K | 0.02% | +500+5.4% | Added |
| Wrapmanager Inc | 9,714 | $360.0K | 0.10% | +1,396+16.8% | Added |
| The PNC Financial Services Group, Inc. | 9,662 | $358.0K | 0.00% | +831+9.4% | Added |
| Canada Pension Plan Investment Board | 9,611 | $356.0K | 0.00% | −48,313−83.4% | Reduced |
| Regions Financial Corp | 9,323 | $345.0K | 0.00% | 00.0% | Unchanged |
| National Asset Management, Inc. | 9,098 | $337.0K | 0.01% | +2,377+35.4% | Added |
| HighTower Advisors, LLC | 9,112 | $336.0K | 0.00% | −18,026−66.4% | Reduced |
| Fox Run Management, L.L.C. | 9,054 | $335.0K | 0.19% | +1,730+23.6% | Added |
| Corton Capital Inc. | 8,809 | $326.0K | 0.14% | +8,809 | New |