Skip to main content

Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
315
+27 vs. Q1 2026
Shares held
101.1M
+5.07M (+5.3%) vs. Q1 2026
Total value
$6.10B
+$538.5M (+9.7%) vs. Q1 2026
New holders
49
126 more added
Sold out
22
87 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 315 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2026: $6.10B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2026.

Institutions holding XENE in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
TD Asset Management Inc9,400$567.4K0.00%−17,674−65.3%Reduced
Thrivent Financial for Lutherans9,122$551.0K0.00%00.0%Unchanged
Capstone Investment Advisors, LLC8,925$538.7K0.00%+8,925New
Ameritas Investment Partners, Inc.8,909$537.7K0.01%+1,771+24.8%Added
First Trust Advisors LP8,811$531.8K0.00%−322−3.5%Reduced
Hudson Bay Capital Management LP8,772$529.5K0.00%−5,300−37.7%Reduced
JustInvest LLC8,745$527.8K0.00%−16−0.2%Reduced
State of Wyoming8,710$525.7K0.05%+7,329+530.7%Added
The PNC Financial Services Group, Inc.8,701$525.2K0.00%+604+7.5%Added
Toroso Investments, LLC8,283$500.0K0.00%+2,058+33.1%Added
Bridgefront Capital, LLC8,239$497.3K0.13%+1,675+25.5%Added
Allstate Corp8,180$493.7K0.00%+8,180New
Great West Life Assurance Co8,061$485.0K0.00%+1,037+14.8%Added
Himension Fund7,666$462.7K0.03%+7,666New
Blackstone Group Inc.7,608$459.2K0.00%+7,608New
Principal Financial Group Inc7,506$453.1K0.00%+1,262+20.2%Added
AQR Capital Management LLC7,263$438.4K0.00%−16−0.2%Reduced
PenderFund Capital Management Ltd.6,850$413.5K0.05%00.0%Unchanged
Blair William & Co6,730$406.2K0.00%+6,730New
Gsa Capital Partners LLP6,293$380.0K0.02%+6,293New
Virtus Investment Advisers, Inc.6,281$379.1K0.09%+93+1.5%Added
Letson Investment Management, Inc.6,000$362.2K0.13%00.0%Unchanged
SG Americas Securities, LLC5,982$361.0K0.00%−3,137−34.4%Reduced
Captrust Financial Advisors5,572$336.3K0.00%+5,572New
CIBC Bancorp USA Inc.5,423$327.3K0.00%+1,074+24.7%Added
CAPROCK Group, Inc.5,406$326.3K0.01%+115+2.2%Added
Ensign Peak Advisors, Inc5,394$325.6K0.00%+200+3.9%Added
Swiss Life Asset Management Ltd5,319$321.1K0.00%+472+9.7%Added
Citizens Financial Group Inc5,291$319.4K0.00%+328+6.6%Added
Aigen Investment Management, LP5,218$315.0K0.09%+1,095+26.6%Added
Advisors Asset Management, Inc.5,086$307.0K0.00%−1,875−26.9%Reduced
Northwestern Mutual Wealth Management Co5,000$301.8K0.00%00.0%Unchanged
LPL Financial LLC4,838$292.0K0.00%−126−2.5%Reduced
Mirae Asset Global Investments Co., Ltd.4,323$260.9K0.00%−16−0.4%Reduced
Oppenheimer Asset Management Inc.4,217$254.5K0.00%−108−2.5%Reduced
PSP Research LLC4,200$253.5K0.13%00.0%Unchanged
Mercer Global Advisors Inc4,193$253.1K0.00%+4,193New
Tower Research Capital LLC (TRC)4,164$251.3K0.01%−1,941−31.8%Reduced
FNY Investment Advisers, LLC4,000$241.0K0.09%−200−4.8%Reduced
Cetera Investment Advisers3,898$235.3K0.00%+274+7.6%Added
Abel Hall, LLC3,809$229.9K0.04%+3,809New
Snowden Capital Advisors LLC3,782$228.3K0.01%−441−10.4%Reduced
Oxford Asset Management LLP3,547$214.1K0.11%−3,337−48.5%Reduced
Inscription Capital, LLC3,431$207.1K0.02%+3,431New
Susquehanna Fundamental Investments, LLC3,405$205.5K0.00%+3,405New
Jones Financial Companies LLLP3,268$195.2K0.00%+869+36.2%Added
Bayforest Capital Ltd3,129$188.9K0.17%+2,574+463.8%Added
Eurizon Capital SGR S.p.A.2,826$170.1K0.00%+177+6.7%Added
Natixis2,037$123.0K0.00%+2,037New
IFP Advisors, Inc1,871$112.9K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,830$110.5K0.00%+879+92.4%Added
GF Fund Management Co. Ltd.1,763$106.4K0.00%+28+1.6%Added
Harbor Investment Advisory, LLC1,393$84.1K0.01%+1,393New
Nykredit A/S1,102$66.5K0.00%+1,102New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,076$64.9K0.00%+800+289.9%Added
Axiom Investment Management LLC1,000$60.4K0.04%00.0%Unchanged
SBI Securities Co., Ltd.988$59.6K0.00%00.0%Unchanged
Quantbot Technologies LP947$57.2K0.00%+785+484.6%Added
Kemnay Advisory Services Inc.876$52.9K0.01%+112+14.7%Added
Global Retirement Partners, LLC873$52.7K0.00%+873New
Signaturefd, LLC760$45.9K0.00%+207+37.4%Added
Ronald Blue Trust, Inc.724$43.7K0.00%−21−2.8%Reduced
GAMMA Investing LLC518$31.3K0.00%+145+38.9%Added
Vanguard Global Advisers, LLC493$29.8K0.00%−1−0.2%Reduced
Optiver Holding B.V.449$27.1K0.00%+449New
SRS Capital Advisors, Inc.441$26.6K0.00%+441New
Huntington National Bank387$23.4K0.00%+99+34.4%Added
Zions Bancorporation, National Association347$20.9K0.00%+42+13.8%Added
Sterling Capital Management LLC345$20.8K0.00%−215−38.4%Reduced
Advisor Group Holdings, Inc.332$20.0K0.00%−57−14.7%Reduced
Basecamp Wealth Advisors LLC280$16.9K0.00%00.0%Unchanged
US Bancorp258$15.6K0.00%−14−5.1%Reduced
National Bank of Canada235$14.2K0.00%00.0%Unchanged
J.Safra Asset Management Corp222$13.4K0.00%−46−17.2%Reduced
Versant Capital Management, Inc221$13.3K0.00%+221New
Farther Finance Advisors, LLC216$13.0K0.00%+27+14.3%Added
IFG Advisory, LLC215$13.0K0.00%+215New
Rockefeller Capital Management L.P.200$12.1K0.00%00.0%Unchanged
Rossby Financial, LCC181$10.9K0.00%00.0%Unchanged
SMA Capital LLC173$10.4K0.00%+34+24.5%Added
Rothschild Investment LLC136$8.21K0.00%+10+7.9%Added
Covestor Ltd130$8.00K0.00%+120+1,200.0%Added
TD Waterhouse Canada Inc.130$7.85K0.00%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.129$7.79K0.00%+125+3,125.0%Added
Danske Bank A/S100$6.04K0.00%00.0%Unchanged
Bell Investment Advisors, Inc100$6.04K0.00%00.0%Unchanged
Flagship Wealth Advisors, LLC100$6.04K0.00%+100New
Clearstead Advisors, LLC94$5.67K0.00%+94New
WPG Advisers, LLC63$3.80K0.00%+54+600.0%Added
Continuum Advisory, LLC48$2.90K0.00%+48New
Silver Grove Financial Group, Inc.39$2.35K0.00%+39New
Cape Investment Advisory, Inc.38$2.29K0.00%+38New
SJS Investment Consulting Inc.37$2.23K0.00%+37New
EverSource Wealth Advisors, LLC35$2.11K0.00%−42−54.5%Reduced
Ameritas Advisory Services, LLC35$2.11K0.00%+35New
Hantz Financial Services, Inc.25$2.00K0.00%00.0%Unchanged
CVA Family Office, LLC33$1.99K0.00%00.0%Unchanged
Parallel Advisors, LLC31$1.87K0.00%−121−79.6%Reduced
Parkside Financial Bank & Trust30$1.81K0.00%00.0%Unchanged
CoreCap Advisors, LLC30$1.81K0.00%+13+76.5%Added