Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 515
- +21 vs. Q1 2026
- Shares held
- 179.7M
- +7.19M (+4.2%) vs. Q1 2026
- Total value
- $14.3B
- +$1.30B (+10.0%) vs. Q1 2026
- New holders
- 67
- 199 more added
- Sold out
- 46
- 162 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Los Angeles Capital Management LLC | 700 | $55.5K | 0.00% | 00.0% | Unchanged |
| Pacer Advisors, Inc. | 629 | $50.0K | 0.00% | +629 | New |
| Archer Investment Corp | 600 | $47.6K | 0.01% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 580 | $46.0K | 0.00% | +579+57,900.0% | Added |
| Harbour Investments, Inc. | 558 | $44.3K | 0.00% | +12+2.2% | Added |
| Silvant Capital Management LLC | 540 | $42.8K | 0.00% | +540 | New |
| Allworth Financial LP | 516 | $40.9K | 0.00% | −6−1.1% | Reduced |
| Mather Group, LLC. | 410 | $32.5K | 0.00% | 00.0% | Unchanged |
| Cassaday & Co Wealth Management LLC | 400 | $31.7K | 0.00% | 00.0% | Unchanged |
| ORG Wealth Partners, LLC | 400 | $31.7K | 0.00% | 00.0% | Unchanged |
| Golden State Wealth Management, LLC | 376 | $29.8K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 370 | $29.3K | 0.00% | 00.0% | Unchanged |
| Brown Brothers Harriman & Co | 341 | $27.0K | 0.00% | 00.0% | Unchanged |
| Salomon & Ludwin, LLC | 332 | $26.3K | 0.00% | 00.0% | Unchanged |
| Wellington-Altus USA Inc. | 317 | $23.8K | 0.02% | 00.0% | Unchanged |
| Eastern Bank | 300 | $23.8K | 0.00% | 00.0% | Unchanged |
| Capital Advisors, Ltd. LLC | 295 | $23.0K | 0.00% | 00.0% | Unchanged |
| Global X Japan Co., Ltd. | 279 | $22.1K | 0.00% | +151+118.0% | Added |
| NBC Securities, Inc. | 273 | $21.6K | 0.00% | 00.0% | Unchanged |
| Nomura Asset Management Co Ltd | 270 | $21.4K | 0.00% | +270 | New |
| Steigerwald, Gordon & Koch Inc. | 265 | $21.0K | 0.00% | −30−10.2% | Reduced |
| E Fund Management (Hong Kong) Co., Ltd. | 260 | $20.6K | 0.01% | +65+33.3% | Added |
| SMA Capital LLC | 260 | $20.6K | 0.01% | +260 | New |
| MTM Investment Management, LLC | 258 | $20.5K | 0.01% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 254 | $20.1K | 0.00% | −4−1.6% | Reduced |
| Trust Co | 250 | $19.8K | 0.00% | +250 | New |
| Caitong International Asset Management Co., Ltd | 248 | $19.7K | 0.00% | +241+3,442.9% | Added |
| Umb Bank N A | 245 | $19.4K | 0.00% | +30+14.0% | Added |
| Harvest Fund Management Co., Ltd | 234 | $19.0K | 0.00% | 00.0% | Unchanged |
| Westside Investment Management, Inc. | 231 | $18.3K | 0.00% | 00.0% | Unchanged |
| FIL Ltd | 227 | $18.0K | 0.00% | +62+37.6% | Added |
| Cedar Mountain Advisors, LLC | 223 | $17.7K | 0.00% | 00.0% | Unchanged |
| Zions Bancorporation, National Association | 214 | $17.0K | 0.00% | +37+20.9% | Added |
| Global Trust Asset Management, LLC | 213 | $16.9K | 0.01% | −5−2.3% | Reduced |
| Owl Creek Wealth Partners LLC | 210 | $16.7K | 0.00% | +40+23.5% | Added |
| CX Institutional | 203 | $16.0K | 0.00% | +1+0.5% | Added |
| Covestor Ltd | 196 | $16.0K | 0.01% | +14+7.7% | Added |
| MH & Associates Securities Management Corp | 200 | $15.9K | 0.01% | 00.0% | Unchanged |
| Atlantic Union Bankshares Corp | 200 | $15.9K | 0.00% | 00.0% | Unchanged |
| LifeSteps Financial, Inc. | 200 | $15.9K | 0.01% | +200 | New |
| Aster Capital Management (DIFC) Ltd | 190 | $15.1K | 0.00% | −360−65.5% | Reduced |
| Tower Research Capital LLC (TRC) | 185 | $14.7K | 0.00% | −4,281−95.9% | Reduced |
| United Financial Planning Group LLC | 158 | $12.5K | 0.01% | 00.0% | Unchanged |
| Strategic Wealth Partners, Ltd. | 150 | $11.9K | 0.00% | 00.0% | Unchanged |
| Silver Grove Financial Group, Inc. | 143 | $11.3K | 0.01% | +143 | New |
| SBI Securities Co., Ltd. | 132 | $10.5K | 0.00% | −29−18.0% | Reduced |
| Bogart Wealth, LLC | 123 | $9.75K | 0.00% | 00.0% | Unchanged |
| Action Point Financial Planning, LLC | 118 | $9.12K | 0.00% | +118 | New |
| LRI Investments, LLC | 110 | $8.72K | 0.00% | 00.0% | Unchanged |
| Quent Capital, LLC | 105 | $8.32K | 0.00% | +6+6.1% | Added |
| WPG Advisers, LLC | 103 | $8.17K | 0.00% | +33+47.1% | Added |
| Spire Wealth Management | 101 | $8.01K | 0.00% | −24−19.2% | Reduced |
| Danske Bank A/S | 100 | $7.93K | 0.00% | 00.0% | Unchanged |
| Main Street Group, LTD | 100 | $7.93K | 0.00% | 00.0% | Unchanged |
| Basecamp Wealth Advisors LLC | 98 | $7.77K | 0.00% | −87−47.0% | Reduced |
| TD Private Client Wealth LLC | 98 | $7.77K | 0.00% | +18+22.5% | Added |
| Massmutual Trust Co FSB | 90 | $7.14K | 0.00% | −53−37.1% | Reduced |
| Bessemer Group Inc | 94 | $7.00K | 0.00% | 00.0% | Unchanged |
| Keating Financial Advisory Services, Inc. | 88 | $6.98K | 0.00% | −2−2.2% | Reduced |
| Ameriflex Group, Inc. | 87 | $6.90K | 0.00% | +87 | New |
| Orion Capital Management LLC | 80 | $6.34K | 0.00% | 00.0% | Unchanged |
| Rossby Financial, LCC | 74 | $5.87K | 0.00% | 00.0% | Unchanged |
| Leonteq Securities AG | 73 | $5.79K | 0.00% | 00.0% | Unchanged |
| Meeder Asset Management Inc | 72 | $5.71K | 0.00% | −80−52.6% | Reduced |
| Truvestments Capital LLC | 70 | $5.53K | 0.00% | +69+6,900.0% | Added |
| Private Wealth Management Group, LLC | 65 | $5.15K | 0.00% | 00.0% | Unchanged |
| First Horizon Corp | 62 | $4.92K | 0.00% | +6+10.7% | Added |
| Bell Investment Advisors, Inc | 61 | $4.84K | 0.00% | 00.0% | Unchanged |
| Hilton Head Capital Partners, LLC | 55 | $4.36K | 0.00% | −298−84.4% | Reduced |
| Triumph Capital Management | 50 | $3.96K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 48 | $3.80K | 0.00% | 00.0% | Unchanged |
| Sachetta, LLC | 47 | $3.73K | 0.00% | +2+4.4% | Added |
| Highline Wealth Partners LLC | 38 | $3.01K | 0.00% | 00.0% | Unchanged |
| Hantz Financial Services, Inc. | 36 | $3.00K | 0.00% | 00.0% | Unchanged |
| Cromwell Holdings LLC | 34 | $2.70K | 0.00% | +16+88.9% | Added |
| Principia Wealth Advisory, LLC | 32 | $2.54K | 0.00% | 00.0% | Unchanged |
| Quarry LP | 29 | $2.30K | 0.00% | +29 | New |
| Cheviot Value Management, LLC | 28 | $2.22K | 0.00% | 00.0% | Unchanged |
| Raffa Wealth Management, LLC | 28 | $2.22K | 0.00% | 00.0% | Unchanged |
| Horizon Investments, LLC | 26 | $2.06K | 0.00% | −22−45.8% | Reduced |
| Bruce G. Allen Investments, LLC | 23 | $1.82K | 0.00% | 00.0% | Unchanged |
| Bryn Mawr Trust Co | 22 | $1.74K | 0.00% | +22 | New |
| TFC Financial Management | 21 | $1.67K | 0.00% | 00.0% | Unchanged |
| Transamerica Financial Advisors, Inc. | 21 | $1.67K | 0.00% | −12−36.4% | Reduced |
| NBT Bank N A | 20 | $1.59K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 19 | $1.51K | 0.00% | +7+58.3% | Added |
| Fortitude Family Office, LLC | 17 | $1.35K | 0.00% | 00.0% | Unchanged |
| Quaker Wealth Management, LLC | 15 | $1.19K | 0.00% | 00.0% | Unchanged |
| MJT & Associates Financial Advisory Group, Inc. | 15 | $1.19K | 0.00% | +15 | New |
| Whipplewood Advisors, LLC | 15 | $1.19K | 0.00% | 00.0% | Unchanged |
| Cornerstone Financial Management LLC | 15 | $1.19K | 0.00% | 00.0% | Unchanged |
| South State Corp. | 14 | $1.11K | 0.00% | 00.0% | Unchanged |
| Mascoma Wealth Management LLC | 14 | $1.11K | 0.00% | 00.0% | Unchanged |
| Cape Investment Advisory, Inc. | 14 | $1.11K | 0.00% | +14 | New |
| Rothschild Investment LLC | 13 | $1.03K | 0.00% | 00.0% | Unchanged |
| Signature Equity Partners, LLC | 12 | $951 | 0.00% | +12 | New |
| Valley National Advisers Inc | 11 | $873 | 0.00% | +11 | New |
| Hughes Financial Services, LLC | 8 | $634 | 0.00% | +2+33.3% | Added |
| Planning Strategies Inc. | 8 | $634 | 0.00% | +8 | New |
| True Wealth Design, LLC | 7 | $556 | 0.00% | 00.0% | Unchanged |