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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

Q2 2026 vs. Q1 2026

How the institutions holding Ionis Pharmaceuticals Inc changed between Q1 2026 and Q2 2026.

All holders in Q2 2026All holders in Q1 2026

13F holders of IONS: Q1 2026 compared with Q2 2026
MeasureQ1 2026Of which not filed for Q2 2026Q2 2026Change
Holders4973515+21
Shares172.6M72.9K179.7M+7.19M (+4.2%)
Value$13.0B$5.48M$14.3B+$1.30B (+10.0%)

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (67)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q2 2026 but not at the end of Q1 2026.

Institutions new to IONS in Q2 2026
InstitutionSharesValue% of portfolio
Capital International Investors823,764$65.3M0.01%
Freestone Grove Partners LP339,967$27.0M0.18%
Life Cycle Investment Partners Ltd219,896$17.4M0.08%
Eagle Health Investments LP194,577$15.4M2.56%
Norges Bank114,359$9.07M0.00%
Bank of Nova Scotia68,548$5.44M0.01%
Jupiter Topco LLC68,191$5.41M0.00%
Y-Intercept (Hong Kong) Ltd67,374$5.34M0.11%
Schroder Investment Management Group58,865$4.75M0.00%
Sovran Advisors, LLC84,984$4.70M0.35%
Ethic Inc.31,679$2.51M0.03%
Jupiter Asset Management Ltd25,949$2.06M0.01%
BI Asset Management Fondsmaeglerselskab A/S25,727$2.04M0.02%
Graham Capital Management, L.P.16,717$1.33M0.04%
BIT Capital GmbH16,300$1.29M0.04%
Dark Forest Capital Management LP15,511$1.23M0.08%
Mitsubishi UFJ Trust & Banking Corp13,446$1.07M0.00%
Militia Capital Management LLC11,400$903.9K0.16%
Evolve Private Wealth, LLC10,653$844.7K0.05%
NewEdge Wealth, LLC8,977$711.8K0.01%
iA Global Asset Management Inc.8,658$686.0K0.01%
CWM Advisors, LLC8,127$644.4K0.03%
Nykredit A/S6,154$488.0K0.00%
Janney Montgomery Scott LLC6,138$487.0K0.00%
VARCOV Co.5,390$427.4K0.16%
Quantbot Technologies LP4,812$381.5K0.02%
Azzad Asset Management Inc4,784$379.3K0.03%
Gateway Investment Advisers LLC4,630$367.1K0.00%
Yorktown Management & Research Co Inc4,400$348.9K0.21%
Bridgefront Capital, LLC3,778$299.6K0.08%
Park Avenue Securities LLC3,677$292.0K0.00%
Sequoia Financial Advisors, LLC3,567$282.8K0.00%
Victrix Investment Advisors3,400$269.6K0.11%
AlphaGrep UK Ltd2,946$233.6K0.07%
University of Texas/Texas Am Investment Managment Co2,923$231.8K0.03%
IFG Advisory, LLC2,678$212.3K0.01%
Kerntke Otto McGlone Wealth Management Group2,654$210.4K0.13%
Global Retirement Partners, LLC2,282$180.9K0.00%
State of Wyoming2,024$160.5K0.02%
Harbor Investment Advisory, LLC1,407$111.6K0.01%
Graticule Asia Macro Advisors LLC1,264$100.2K0.01%
SRS Capital Advisors, Inc.1,004$79.6K0.00%
Tripletail Wealth Management, LLC850$69.5K0.08%
Pacer Advisors, Inc.629$50.0K0.00%
Silvant Capital Management LLC540$42.8K0.00%
Nomura Asset Management Co Ltd270$21.4K0.00%
SMA Capital LLC260$20.6K0.01%
Trust Co250$19.8K0.00%
LifeSteps Financial, Inc.200$15.9K0.01%
Silver Grove Financial Group, Inc.143$11.3K0.01%
Action Point Financial Planning, LLC118$9.12K0.00%
Ameriflex Group, Inc.87$6.90K0.00%
Quarry LP29$2.30K0.00%
Bryn Mawr Trust Co22$1.74K0.00%
MJT & Associates Financial Advisory Group, Inc.15$1.19K0.00%
Cape Investment Advisory, Inc.14$1.11K0.00%
Signature Equity Partners, LLC12$9510.00%
Valley National Advisers Inc11$8730.00%
Planning Strategies Inc.8$6340.00%
SHP Wealth Management4$3170.00%
Downshift Financial, LLC4$3170.00%
Plante Moran Financial Advisors, LLC2$1590.00%
Wealth Enhancement Trust Services, Inc.2$1590.00%
Activest Wealth Management1$790.00%
Medallion Wealth Advisors, LLC1$790.00%
Evolution Advisers, Inc.2$00.00%
Coppell Advisory Solutions LLC26––

Sold out (46)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q1 2026 and filed for Q2 2026 without it.

Institutions that sold out of IONS in Q2 2026
InstitutionShares, Q1 2026Value, Q1 2026
Zurich Insurance Group Ltd239,645$18.0M
Ikarian Capital, LLC127,038$9.54M
Integral Health Asset Management, LLC125,000$9.39M
Winton Group Ltd106,532$8.00M
Lisanti Capital Growth, LLC75,699$5.68M
Tudor Investment Corp Et Al48,244$3.62M
West Michigan Advisors, LLC44,614$3.35M
Prelude Capital Management, LLC29,658$2.23M
StemPoint Capital LP26,385$1.98M
Florida Financial Advisors, LLC25,886$1.94M
EAM Investors, LLC20,608$1.55M
Readystate Asset Management LP20,436$1.53M
Landscape Capital Management, L.L.C.20,146$1.51M
Legato Capital Management LLC19,840$1.49M
Highland Capital Management, LLC12,819$962.6K
Capstone Capital Management Ltd21,447$832.4K
Aigen Investment Management, LP8,790$660.0K
Ground Swell Capital, LLC7,285$547.0K
Principal Financial Group Inc7,019$527.1K
Cynosure Management, LLC5,614$421.6K
Virtu Financial LLC5,342$401.0K
Lighthouse Investment Partners, LLC4,970$373.2K
Farallon Capital Management, L.L.C.4,800$360.4K
Vise Technologies, Inc.4,305$340.6K
Inspire Advisors, LLC4,120$309.4K
Optas, LLC4,034$302.9K
Congress Asset Management Co3,946$296.3K
EntryPoint Capital, LLC2,963$222.5K
Fideuram Asset Management (Ireland) dac2,213$181.6K
Advisors Asset Management, Inc.1,878$141.0K
Stephens Inc26,761$91.4K
MAI Capital Management940$70.6K
Root Financial Partners, LLC681$51.1K
Quadrant Capital Group LLC616$46.3K
Advisory Services Network, LLC604$45.4K
Bayforest Capital Ltd413$31.0K
RWM Asset Management, LLC375$28.2K
Employees Retirement System of Texas378$28.0K
Sound Income Strategies, LLC300$22.5K
Twin Peaks Wealth Advisors, LLC215$16.1K
Elequin Capital LP208$15.6K
Wealth Preservation Advisors, LLC150$11.3K
Clear Investment Research, LLC71$5.33K
Crewe Advisors LLC48$3.60K
Aspect Partners, LLC20$1.50K
Dunhill Financial, LLC2$201

Not filed for Q2 2026 yet (3)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q1 2026 and haven't filed a 13F for Q2 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding IONS in Q1 2026 that haven't filed for Q2 2026
InstitutionShares, Q1 2026Value, Q1 2026
Janus Henderson Group PLC68,191$5.12M
CWM, LLC3,717$279.1K
Sunbelt Securities, Inc.1,014$76.1K