Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 290
- +49 vs. Q4 2025
- Shares held
- 100.2M
- +16.7M (+20.0%) vs. Q4 2025
- Total value
- $5.80B
- +$2.06B (+55.0%) vs. Q4 2025
- New holders
- 82
- 123 more added
- Sold out
- 33
- 60 more reduced
4 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Peregrine Capital Management LLC | 143,136 | $8.32M | 0.31% | −31,715−18.1% | Reduced |
| Woodline Partners LP | 150,302 | $8.74M | 0.03% | +150,302 | New |
| Jump Financial, LLC | 155,776 | $9.06M | 0.13% | +124,789+402.7% | Added |
| Swiss National Bank | 157,700 | $9.17M | 0.01% | +43,700+38.3% | Added |
| Foresite Capital Management IV, LLC | 160,000 | $9.30M | 3.92% | 00.0% | Unchanged |
| Deutsche Bank AG | 162,682 | $9.46M | 0.00% | −27,551−14.5% | Reduced |
| ExodusPoint Capital Management, LP | 173,425 | $10.1M | 0.10% | +173,425 | New |
| Susquehanna International Group, LLP | 177,137 | $10.3M | 0.01% | +168,818+2,029.3% | Added |
| DnB Asset Management AS | 181,085 | $10.5M | 0.04% | −91,746−33.6% | Reduced |
| NEXTBio Capital Management LP | 183,225 | $10.7M | 4.95% | −479−0.3% | Reduced |
| New York State Common Retirement Fund | 188,505 | $11.0M | 0.02% | +1,800+1.0% | Added |
| Charles Schwab Investment Management Inc | 189,080 | $11.0M | 0.00% | +210.0% | Added |
| Silverarc Capital Management, LLC | 197,759 | $11.5M | 1.36% | +197,759 | New |
| Integral Health Asset Management, LLC | 200,000 | $11.6M | 0.62% | +200,000 | New |
| Millennium Management LLC | 201,785 | $11.7M | 0.01% | −433,271−68.2% | Reduced |
| Patient Square Capital LP | 227,000 | $13.2M | 2.34% | +90,500+66.3% | Added |
| ADAR1 Capital Management, LLC | 228,899 | $13.3M | 0.80% | +24,930+12.2% | Added |
| Balyasny Asset Management LLC | 233,905 | $13.6M | 0.03% | +149,545+177.3% | Added |
| Barclays PLC | 238,209 | $13.9M | 0.00% | −362,755−60.4% | Reduced |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 238,600 | $13.9M | 0.47% | +238,600 | New |
| Allspring Global Investments Holdings, LLC | 246,306 | $14.0M | 0.02% | +246,306 | New |
| Nicholas Investment Partners, LP | 247,101 | $14.4M | 1.04% | +4,112+1.7% | Added |
| Nan Fung Trinity (HK) Ltd | 247,765 | $14.4M | 1.58% | +20,800+9.2% | Added |
| Nuveen, LLC | 250,036 | $14.5M | 0.00% | +33,798+15.6% | Added |
| DAFNA Capital Management LLC | 250,772 | $14.6M | 3.32% | −37,167−12.9% | Reduced |
| State of Wisconsin Investment Board | 254,483 | $14.8M | 0.03% | +48,914+23.8% | Added |
| Redmile Group, LLC | 262,674 | $15.3M | 1.01% | +128,792+96.2% | Added |
| Algert Global LLC | 264,200 | $15.4M | 0.23% | +141,011+114.5% | Added |
| Bank of America Corp | 265,267 | $15.4M | 0.00% | +43,899+19.8% | Added |
| Boothbay Fund Management, LLC | 270,412 | $15.7M | 0.37% | +234,731+657.9% | Added |
| Soleus Capital Management, L.P. | 292,000 | $17.0M | 0.69% | +292,000 | New |
| Renaissance Technologies LLC | 300,500 | $17.5M | 0.03% | +300,500 | New |
| Sofinnova Investments, Inc. | 305,216 | $17.7M | 0.89% | +245,316+409.5% | Added |
| Schonfeld Strategic Advisors LLC | 324,722 | $18.9M | 0.15% | +324,722 | New |
| TimesSquare Capital Management, LLC | 359,293 | $20.9M | 0.35% | −173,447−32.6% | Reduced |
| Baker Bros. Advisors LP | 370,208 | $21.5M | 0.12% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 375,166 | $21.8M | 0.00% | +374,930+158,868.6% | Added |
| Bank of New York Mellon Corp | 396,138 | $23.0M | 0.00% | +8,980+2.3% | Added |
| Trails Edge Capital Partners, LP | 440,000 | $25.6M | 6.02% | −157,092−26.3% | Reduced |
| Logos Global Management LP | 450,000 | $26.2M | 1.35% | +450,000 | New |
| Adage Capital Partners GP, L.L.C. | 470,000 | $27.3M | 0.04% | −215,100−31.4% | Reduced |
| Morgan Stanley | 473,759 | $27.5M | 0.00% | +179,427+61.0% | Added |
| Candriam Luxembourg S.C.A. | 476,494 | $27.7M | 0.14% | +59,092+14.2% | Added |
| Novo Holdings A/S | 485,438 | $28.2M | 2.29% | +485,438 | New |
| Octagon Capital Advisors LP | 490,000 | $28.5M | 3.15% | +490,000 | New |
| Tudor Investment Corp Et Al | 495,591 | $28.8M | 0.16% | +241,589+95.1% | Added |
| Parkman Healthcare Partners LLC | 497,035 | $28.9M | 3.00% | +342,851+222.4% | Added |
| Northern Trust Corp | 527,783 | $30.7M | 0.00% | +89,069+20.3% | Added |
| Vanguard Portfolio Management LLC | 543,062 | $31.6M | 0.00% | +543,062 | New |
| Loomis Sayles & Co L P | 564,897 | $32.8M | 0.04% | −47,135−7.7% | Reduced |
| MPM Oncology Impact Management LP | 588,706 | $34.2M | 2.64% | +103,086+21.2% | Added |
| Two Sigma Investments, LP | 606,085 | $35.2M | 0.03% | +169,342+38.8% | Added |
| Standard Life Aberdeen plc | 609,929 | $35.5M | 0.06% | −140,362−18.7% | Reduced |
| Vestal Point Capital, LP | 639,900 | $37.2M | 1.04% | +39,900+6.7% | Added |
| Pictet Asset Management Holding SA | 679,709 | $39.2M | 0.04% | +53,724+8.6% | Added |
| American Century Companies Inc | 679,314 | $39.5M | 0.02% | −1,159−0.2% | Reduced |
| Fiera Capital Corp | 709,529 | $41.3M | 0.14% | +23,473+3.4% | Added |
| Rock Springs Capital Management LP | 763,020 | $44.4M | 2.62% | −24,768−3.1% | Reduced |
| Goldman Sachs Group Inc | 769,875 | $44.8M | 0.01% | +73,828+10.6% | Added |
| First Turn Management, LLC | 786,844 | $45.8M | 5.11% | −12,899−1.6% | Reduced |
| Commodore Capital LP | 825,000 | $48.0M | 2.78% | −975,000−54.2% | Reduced |
| Capital World Investors | 840,072 | $48.9M | 0.01% | +184,335+28.1% | Added |
| T. Rowe Price Investment Management, Inc. | 951,955 | $55.4M | 0.04% | +404,342+73.8% | Added |
| Federated Hermes, Inc. | 972,237 | $56.5M | 0.09% | +300,000+44.6% | Added |
| OrbiMed Advisors LLC | 1,059,971 | $61.6M | 1.40% | +612,771+137.0% | Added |
| Alliancebernstein L.P. | 1,403,297 | $62.9M | 0.02% | −190,517−12.0% | Reduced |
| Geode Capital Management, LLC | 1,092,932 | $63.5M | 0.00% | +140,253+14.7% | Added |
| Franklin Resources Inc | 1,280,577 | $74.5M | 0.02% | +522,518+68.9% | Added |
| Alyeska Investment Group, L.P. | 1,299,469 | $75.6M | 0.21% | +1,299,469 | New |
| Siren, L.L.C. | 1,318,564 | $76.7M | 2.13% | +505,803+62.2% | Added |
| Jennison Associates LLC | 1,318,814 | $76.7M | 0.05% | +26,759+2.1% | Added |
| Price T Rowe Associates Inc | 1,329,591 | $77.3M | 0.01% | +467,291+54.2% | Added |
| Braidwell LP | 1,338,452 | $77.8M | 2.60% | −486,624−26.7% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,342,028 | $78.0M | 0.09% | +281,807+26.6% | Added |
| Caligan Partners LP | 1,393,027 | $81.0M | 5.73% | +843,362+153.4% | Added |
| Westfield Capital Management Co LP | 1,401,483 | $81.5M | 0.34% | +174,712+14.2% | Added |
| Holocene Advisors, LP | 1,518,686 | $88.3M | 0.21% | +236,605+18.5% | Added |
| Deerfield Management Company, L.P. (Series C) | 1,615,696 | $94.0M | 1.11% | +1,073,676+198.1% | Added |
| Affinity Asset Advisors, LLC | 1,675,000 | $97.4M | 5.71% | +425,000+34.0% | Added |
| State Street Corp | 1,720,533 | $100.0M | 0.00% | +227,983+15.3% | Added |
| JPMorgan Chase & Co | 1,923,610 | $106.9M | 0.01% | +429,578+28.8% | Added |
| Citadel Advisors LLC | 2,652,990 | $154.3M | 0.11% | +1,331,777+100.8% | Added |
| Capital International Investors | 2,674,727 | $155.5M | 0.04% | −740,232−21.7% | Reduced |
| Janus Henderson Group PLC | 4,175,982 | $242.9M | 0.12% | +91,948+2.3% | Added |
| Polar Capital Holdings Plc | 4,405,312 | $256.2M | 1.12% | +1,939,618+78.7% | Added |
| Driehaus Capital Management LLC | 4,491,653 | $261.2M | 1.92% | −47,038−1.0% | Reduced |
| Wellington Management Group LLP | 4,829,641 | $280.8M | 0.05% | +64,862+1.4% | Added |
| BlackRock, Inc. | 5,640,118 | $328.0M | 0.01% | +539,834+10.6% | Added |
| Avoro Capital Advisors LLC | 5,777,777 | $336.0M | 3.31% | +353,333+6.5% | Added |
| FMR LLC | 10,818,491 | $629.1M | 0.03% | +1,898,241+21.3% | Added |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −452,147−100.0% | Sold out |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −366,435−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −259,320−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −200,791−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −173,882−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −162,551−100.0% | Sold out |
| Moore Capital Management, LP | 0 | $0 | 0.00% | −140,000−100.0% | Sold out |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −119,186−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −114,826−100.0% | Sold out |
| Squadron Capital Management LLC | 0 | $0 | 0.00% | −105,551−100.0% | Sold out |