Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 206
- +2 vs. Q1 2025
- Shares held
- 83.1M
- +6.43M (+8.4%) vs. Q1 2025
- Total value
- $2.60B
- +$26.6M (+1.0%) vs. Q1 2025
- New holders
- 42
- 77 more added
- Sold out
- 40
- 55 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| MetLife Investment Management | 45,547 | $1.43M | 0.01% | +45,547 | New |
| HighVista Strategies LLC | 45,620 | $1.43M | 0.52% | −21,168−31.7% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 47,457 | $1.49M | 0.01% | 00.0% | Unchanged |
| Prudential Financial Inc | 47,755 | $1.53M | 0.00% | +8,755+22.4% | Added |
| Erste Asset Management GmbH | 50,000 | $1.62M | 0.01% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 52,136 | $1.63M | 0.00% | −23,205−30.8% | Reduced |
| Bamco Inc | 56,000 | $1.75M | 0.00% | −44,100−44.1% | Reduced |
| Voya Investment Management LLC | 59,465 | $1.86M | 0.00% | +11,400+23.7% | Added |
| Invesco Ltd. | 59,598 | $1.87M | 0.00% | −146,165−71.0% | Reduced |
| Nebula Research & Development LLC | 60,223 | $1.88M | 0.16% | +13,662+29.3% | Added |
| California State Teachers Retirement System | 60,233 | $1.89M | 0.00% | +4,741+8.5% | Added |
| State of New Jersey Common Pension Fund D | 61,772 | $1.93M | 0.01% | +11,355+22.5% | Added |
| Man Group plc | 62,348 | $1.95M | 0.00% | +62,348 | New |
| Raymond James Financial Inc | 65,214 | $2.04M | 0.00% | +1,829+2.9% | Added |
| Balyasny Asset Management LLC | 68,869 | $2.16M | 0.00% | −198,273−74.2% | Reduced |
| Nicholas Investment Partners, LP | 68,896 | $2.16M | 0.19% | −18,072−20.8% | Reduced |
| T. Rowe Price Investment Management, Inc. | 76,943 | $2.41M | 0.00% | −720,043−90.3% | Reduced |
| Soleus Capital Management, L.P. | 78,800 | $2.47M | 0.17% | +78,800 | New |
| Legal & General Group Plc | 81,792 | $2.56M | 0.00% | +21,386+35.4% | Added |
| J. Safra Sarasin Holding AG | 82,048 | $2.57M | 0.04% | +51,475+168.4% | Added |
| Moore Capital Management, LP | 90,000 | $2.82M | 0.06% | +35,000+63.6% | Added |
| Two Sigma Advisers, LP | 95,300 | $2.98M | 0.01% | −203,500−68.1% | Reduced |
| Mutual of America Capital Management LLC | 95,568 | $2.99M | 0.03% | +46,805+96.0% | Added |
| Caption Management, LLC | 100,940 | $3.16M | 0.29% | +100,940 | New |
| Algert Global LLC | 102,345 | $3.20M | 0.07% | −21,070−17.1% | Reduced |
| Deutsche Bank AG | 104,534 | $3.27M | 0.00% | +50,823+94.6% | Added |
| Avidity Partners Management LP | 107,891 | $3.38M | 0.68% | −121,109−52.9% | Reduced |
| Rhumbline Advisers | 109,700 | $3.43M | 0.00% | +109,671+378,175.9% | Added |
| Wells Fargo & Company | 112,562 | $3.52M | 0.00% | +46,650+70.8% | Added |
| Citadel Advisors LLC | 120,045 | $3.76M | 0.00% | −567,043−82.5% | Reduced |
| Ameriprise Financial Inc | 122,026 | $3.82M | 0.00% | +18,402+17.8% | Added |
| Swiss National Bank | 124,300 | $3.89M | 0.00% | −1,300−1.0% | Reduced |
| Schroder Investment Management Group | 129,103 | $4.04M | 0.00% | −8,118−5.9% | Reduced |
| D. E. Shaw & Co., Inc. | 141,783 | $4.44M | 0.00% | −10,405−6.8% | Reduced |
| Royal Bank of Canada | 147,226 | $4.61M | 0.00% | +87,860+148.0% | Added |
| Neuberger Berman Group LLC | 147,411 | $4.61M | 0.00% | +102,559+228.7% | Added |
| Parkman Healthcare Partners LLC | 150,373 | $4.71M | 0.54% | −24,203−13.9% | Reduced |
| Barclays PLC | 152,770 | $4.78M | 0.00% | +133,500+692.8% | Added |
| UBS Group AG | 153,058 | $4.79M | 0.00% | +47,725+45.3% | Added |
| Nan Fung Trinity (HK) Ltd | 158,605 | $4.96M | 0.59% | +158,605 | New |
| Foresite Capital Management IV, LLC | 160,000 | $5.01M | 4.05% | +160,000 | New |
| Foresite Capital Management VI LLC | 160,000 | $5.01M | 2.82% | +160,000 | New |
| New York State Common Retirement Fund | 166,472 | $5.21M | 0.01% | +24,100+16.9% | Added |
| State of Wisconsin Investment Board | 174,850 | $5.47M | 0.01% | +77,701+80.0% | Added |
| AXA S.A. | 175,632 | $5.50M | 0.02% | +282+0.2% | Added |
| First Light Asset Management, LLC | 188,367 | $5.90M | 0.76% | −439,537−70.0% | Reduced |
| Charles Schwab Investment Management Inc | 192,242 | $6.02M | 0.00% | +192,242 | New |
| Great Point Partners LLC | 200,000 | $6.26M | 4.07% | −45,272−18.5% | Reduced |
| Perceptive Advisors LLC | 200,791 | $6.28M | 0.24% | −124,533−38.3% | Reduced |
| Susquehanna International Group, LLP | 222,352 | $6.96M | 0.01% | +222,352 | New |
| Nuveen, LLC | 228,567 | $7.15M | 0.00% | +228,567 | New |
| Federated Hermes, Inc. | 232,500 | $7.28M | 0.01% | 00.0% | Unchanged |
| DnB Asset Management AS | 234,157 | $7.33M | 0.03% | +4,675+2.0% | Added |
| Granahan Investment Management Inc | 240,038 | $7.51M | 0.31% | +56,230+30.6% | Added |
| ADAR1 Capital Management, LLC | 259,503 | $8.12M | 1.32% | +131,955+103.5% | Added |
| DAFNA Capital Management LLC | 287,939 | $9.01M | 2.49% | +14,200+5.2% | Added |
| MPM Oncology Impact Management LP | 323,398 | $10.1M | 1.75% | +20,000+6.6% | Added |
| Bank of America Corp | 358,432 | $11.2M | 0.00% | +221,863+162.5% | Added |
| Baker Bros. Advisors LP | 370,208 | $11.6M | 0.11% | +22,800+6.6% | Added |
| Dimensional Fund Advisors LP | 379,988 | $11.9M | 0.00% | +165,128+76.9% | Added |
| Morgan Stanley | 387,596 | $12.1M | 0.00% | +258,105+199.3% | Added |
| Candriam Luxembourg S.C.A. | 396,636 | $12.4M | 0.07% | −58,014−12.8% | Reduced |
| UBS Asset Management Americas Inc | 404,384 | $12.7M | 0.00% | +340,816+536.1% | Added |
| Bank of New York Mellon Corp | 436,020 | $13.6M | 0.00% | +184,873+73.6% | Added |
| Assenagon Asset Management S.A. | 436,974 | $13.7M | 0.02% | +195,768+81.2% | Added |
| Saturn V Capital Management LLC | 468,364 | $14.7M | 5.94% | +54,653+13.2% | Added |
| Northern Trust Corp | 489,940 | $15.3M | 0.00% | +408,916+504.7% | Added |
| Standard Life Aberdeen plc | 521,492 | $16.3M | 0.03% | +117,338+29.0% | Added |
| Fiera Capital Corp | 530,683 | $16.6M | 0.06% | +1,241+0.2% | Added |
| Deerfield Management Company, L.P. (Series C) | 542,020 | $17.0M | 0.31% | +542,020 | New |
| Goldman Sachs Group Inc | 561,800 | $17.6M | 0.00% | +119,068+26.9% | Added |
| TimesSquare Capital Management, LLC | 571,242 | $17.9M | 0.26% | −174,309−23.4% | Reduced |
| Capital World Investors | 655,737 | $20.5M | 0.00% | −1,568,978−70.5% | Reduced |
| Loomis Sayles & Co L P | 657,165 | $20.6M | 0.03% | −15,846−2.4% | Reduced |
| First Turn Management, LLC | 660,617 | $20.7M | 3.86% | −22,834−3.3% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 661,082 | $20.7M | 0.05% | −42,713−6.1% | Reduced |
| Franklin Resources Inc | 666,466 | $20.9M | 0.01% | +175,346+35.7% | Added |
| American Century Companies Inc | 679,857 | $21.3M | 0.01% | +679,857 | New |
| Jennison Associates LLC | 696,383 | $21.8M | 0.01% | −80,310−10.3% | Reduced |
| Siren, L.L.C. | 812,761 | $25.4M | 1.32% | +80,000+10.9% | Added |
| Vanguard Group Inc | 873,228 | $27.3M | 0.00% | +536,714+159.5% | Added |
| Millennium Management LLC | 882,835 | $27.6M | 0.02% | +648,779+277.2% | Added |
| Rock Springs Capital Management LP | 931,681 | $29.2M | 1.82% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 947,877 | $29.7M | 0.75% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 970,343 | $30.4M | 0.00% | +900,746+1,294.2% | Added |
| Marshall Wace, LLP | 1,020,254 | $31.9M | 0.04% | +262,109+34.6% | Added |
| Affinity Asset Advisors, LLC | 1,100,000 | $34.4M | 5.09% | −228,175−17.2% | Reduced |
| Westfield Capital Management Co LP | 1,152,605 | $36.1M | 0.15% | −238,765−17.2% | Reduced |
| JPMorgan Chase & Co | 1,256,581 | $39.3M | 0.00% | −101,021−7.4% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,290,100 | $40.4M | 0.07% | −624,649−32.6% | Reduced |
| Deep Track Capital, LP | 1,350,000 | $42.3M | 1.36% | +350,000+35.0% | Added |
| State Street Corp | 1,380,460 | $43.2M | 0.00% | +1,074,840+351.7% | Added |
| Pictet Asset Management Holding SA | 1,474,449 | $46.2M | 0.05% | −3,168−0.2% | Reduced |
| Alliancebernstein L.P. | 1,518,527 | $47.5M | 0.02% | +189,141+14.2% | Added |
| Holocene Advisors, LP | 1,809,475 | $56.6M | 0.14% | +1,809,475 | New |
| Vestal Point Capital, LP | 2,000,000 | $62.6M | 3.30% | +700,000+53.8% | Added |
| Wellington Management Group LLP | 2,174,761 | $68.1M | 0.01% | −1,614,436−42.6% | Reduced |
| Polar Capital Holdings Plc | 2,703,256 | $84.6M | 0.44% | +80,217+3.1% | Added |
| Commodore Capital LP | 3,025,000 | $94.7M | 6.68% | +700,000+30.1% | Added |
| Capital International Investors | 3,181,549 | $99.6M | 0.02% | +92,819+3.0% | Added |