Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 206
- +2 vs. Q1 2025
- Shares held
- 83.1M
- +6.43M (+8.4%) vs. Q1 2025
- Total value
- $2.60B
- +$26.6M (+1.0%) vs. Q1 2025
- New holders
- 42
- 77 more added
- Sold out
- 40
- 55 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Twin Peaks Wealth Advisors, LLC | 1 | $36 | 0.00% | +1 | New |
| American National Bank | 5 | $157 | 0.00% | +5 | New |
| Bell Investment Advisors, Inc | 11 | $345 | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 14 | $438 | 0.00% | +6+75.0% | Added |
| Park Place Capital Corp | 16 | $513 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 26 | $814 | 0.00% | −32−55.2% | Reduced |
| Ronald Blue Trust, Inc. | 28 | $876 | 0.00% | −242−89.6% | Reduced |
| Parkside Financial Bank & Trust | 30 | $939 | 0.00% | +30 | New |
| CVA Family Office, LLC | 33 | $1.03K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 35 | $1.10K | 0.00% | +23+191.7% | Added |
| Whittier Trust Co of Nevada Inc | 36 | $1.13K | 0.00% | 00.0% | Unchanged |
| Cape Investment Advisory, Inc. | 39 | $1.22K | 0.00% | +39 | New |
| Principal Securities, Inc. | 68 | $2.13K | 0.00% | +10+17.2% | Added |
| J.Safra Asset Management Corp | 87 | $2.72K | 0.00% | +3+3.6% | Added |
| Skopos Labs, Inc. | 103 | $3.22K | 0.00% | +103 | New |
| Caitong International Asset Management Co., Ltd | 104 | $3.25K | 0.00% | −801−88.5% | Reduced |
| Rothschild Investment LLC | 130 | $4.07K | 0.00% | +130 | New |
| Parallel Advisors, LLC | 135 | $4.23K | 0.00% | −553−80.4% | Reduced |
| US Bancorp | 181 | $5.67K | 0.00% | −94−34.2% | Reduced |
| Sterling Capital Management LLC | 184 | $5.76K | 0.00% | +184 | New |
| Spire Wealth Management | 200 | $6.26K | 0.00% | 00.0% | Unchanged |
| United Community Bank | 200 | $6.26K | 0.00% | +200 | New |
| CWM, LLC | 237 | $7.00K | 0.00% | −2−0.8% | Reduced |
| National Bank of Canada | 235 | $7.35K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 252 | $8.00K | 0.00% | 00.0% | Unchanged |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 276 | $8.64K | 0.00% | 00.0% | Unchanged |
| First Horizon Advisors, Inc. | 345 | $10.8K | 0.00% | −25−6.8% | Reduced |
| Clearstead Advisors, LLC | 347 | $10.9K | 0.00% | +129+59.2% | Added |
| State of Wyoming | 541 | $16.9K | 0.00% | −33−5.7% | Reduced |
| Signaturefd, LLC | 661 | $20.7K | 0.00% | +476+257.3% | Added |
| Nisa Investment Advisors, LLC | 689 | $21.6K | 0.00% | +689 | New |
| Farther Finance Advisors, LLC | 784 | $24.5K | 0.00% | +784 | New |
| Danske Bank A/S | 800 | $25.0K | 0.00% | +800 | New |
| Mount Yale Investment Advisors, LLC | 1,015 | $31.8K | 0.00% | +1,015 | New |
| Advisor Group Holdings, Inc. | 1,225 | $40.2K | 0.00% | +1,034+541.4% | Added |
| L1 Capital Pty Ltd | 1,296 | $40.6K | 0.00% | +1,296 | New |
| KBC Group NV | 1,871 | $59.0K | 0.00% | −890−32.2% | Reduced |
| GF Fund Management Co. Ltd. | 1,952 | $61.1K | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 1,865 | $61.5K | 0.00% | −56−2.9% | Reduced |
| Quarry LP | 2,000 | $62.6K | 0.01% | 00.0% | Unchanged |
| Amalgamated Bank | 2,595 | $81.0K | 0.00% | +2,595 | New |
| Virtus Investment Advisers, Inc. | 2,867 | $89.7K | 0.03% | −1,294−31.1% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,964 | $92.8K | 0.00% | +403+15.7% | Added |
| The PNC Financial Services Group, Inc. | 3,462 | $108.4K | 0.00% | −1,758−33.7% | Reduced |
| Group One Trading, L.P. | 4,653 | $145.6K | 0.00% | +4,653 | New |
| Northwestern Mutual Wealth Management Co | 5,000 | $156.5K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 5,357 | $167.7K | 0.00% | +5,307+10,614.0% | Added |
| Great West Life Assurance Co | 7,024 | $220.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 7,758 | $242.8K | 0.01% | +7,758 | New |
| Renaissance Technologies LLC | 8,600 | $269.2K | 0.00% | −146,100−94.4% | Reduced |
| CIBC World Markets Corp | 9,363 | $293.1K | 0.00% | +9,363 | New |
| Allianz Asset Management GmbH | 9,400 | $294.2K | 0.00% | 00.0% | Unchanged |
| Legato Capital Management LLC | 9,622 | $301.2K | 0.04% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 10,538 | $329.8K | 0.00% | −12,416−54.1% | Reduced |
| Public Employees Retirement Association of Colorado | 10,633 | $333.0K | 0.00% | 00.0% | Unchanged |
| Elmwood Wealth Management, Inc. | 10,824 | $338.8K | 0.13% | −183−1.7% | Reduced |
| Knott David M Jr | 10,962 | $343.1K | 0.16% | −4,904−30.9% | Reduced |
| Supplemental Annuity Collective Trust of NJ | 11,000 | $344.3K | 0.10% | 00.0% | Unchanged |
| Advisors Asset Management, Inc. | 12,205 | $382.0K | 0.01% | −2,076−14.5% | Reduced |
| KLP Kapitalforvaltning AS | 12,800 | $400.6K | 0.00% | 00.0% | Unchanged |
| Brinker Capital Investments, LLC | 14,916 | $466.9K | 0.00% | −615−4.0% | Reduced |
| PEAK6 LLC | 15,000 | $469.5K | 0.02% | +15,000 | New |
| China Universal Asset Management Co., Ltd. | 15,412 | $482.4K | 0.05% | +59+0.4% | Added |
| CIBC World Markets Inc. | 16,335 | $511.3K | 0.00% | 00.0% | Unchanged |
| Jump Financial, LLC | 16,991 | $531.8K | 0.01% | +16,991 | New |
| Police & Firemen's Retirement System of New Jersey | 17,358 | $543.3K | 0.01% | +17,358 | New |
| Natixis Advisors, L.P. | 17,424 | $545.0K | 0.00% | −6,586−27.4% | Reduced |
| Teacher Retirement System of Texas | 17,534 | $548.8K | 0.00% | +95+0.5% | Added |
| BNP Paribas Arbitrage, SA | 17,844 | $558.5K | 0.00% | +14,634+455.9% | Added |
| ProShare Advisors LLC | 18,448 | $577.4K | 0.00% | +18,448 | New |
| Arizona State Retirement System | 18,956 | $593.3K | 0.00% | +377+2.0% | Added |
| SG Americas Securities, LLC | 19,177 | $600.0K | 0.00% | +10,522+121.6% | Added |
| Stifel Financial Corp | 20,622 | $645.5K | 0.00% | +95+0.5% | Added |
| Birchview Capital, LP | 21,000 | $657.3K | 0.65% | 00.0% | Unchanged |
| Oxford Asset Management LLP | 21,138 | $661.6K | 0.22% | +14,964+242.4% | Added |
| Assetmark, Inc | 21,250 | $665.1K | 0.00% | +1,316+6.6% | Added |
| Handelsbanken Fonder AB | 22,700 | $711.0K | 0.00% | 00.0% | Unchanged |
| SEI Investments Co | 22,723 | $711.2K | 0.00% | +13,319+141.6% | Added |
| Rathbone Brothers plc | 23,666 | $740.7K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 23,866 | $747.0K | 0.00% | +4,910+25.9% | Added |
| CenterBook Partners LP | 24,664 | $772.0K | 0.04% | +2,453+11.0% | Added |
| Readystate Asset Management LP | 24,814 | $776.7K | 0.03% | +24,814 | New |
| NJ State Employees Deferred Compensation Plan | 25,000 | $782.5K | 0.09% | 00.0% | Unchanged |
| Polar Asset Management Partners Inc. | 25,300 | $791.9K | 0.02% | +25,300 | New |
| Manufacturers Life Insurance Company, The | 26,079 | $816.3K | 0.00% | +26,079 | New |
| Ensign Peak Advisors, Inc | 26,094 | $816.7K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 26,100 | $816.9K | 0.40% | +20,000+327.9% | Added |
| Harbor Capital Advisors, Inc. | 30,036 | $940.0K | 0.04% | −26,555−46.9% | Reduced |
| TLS Advisors LLC | 32,956 | $1.03M | 3.22% | 00.0% | Unchanged |
| Intech Investment Management LLC | 34,312 | $1.07M | 0.01% | +34,312 | New |
| Rhenman & Partners Asset Management AB | 35,000 | $1.10M | 0.14% | 00.0% | Unchanged |
| Citigroup Inc | 36,290 | $1.14M | 0.00% | +29,261+416.3% | Added |
| Price T Rowe Associates Inc | 37,935 | $1.19M | 0.00% | +37,935 | New |
| Envestnet Asset Management Inc | 39,403 | $1.23M | 0.00% | −3,447−8.0% | Reduced |
| Artia Global Partners LP | 40,000 | $1.25M | 0.32% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 39,000 | $1.26M | 0.00% | 00.0% | Unchanged |
| Alps Advisors Inc | 41,380 | $1.30M | 0.01% | −13,952−25.2% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 41,648 | $1.30M | 0.00% | +41,648 | New |
| Woodline Partners LP | 43,380 | $1.36M | 0.01% | +43,380 | New |
| Jane Street Group, LLC | 43,676 | $1.37M | 0.00% | +43,676 | New |