Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 159
- +5 vs. Q3 2022
- Shares held
- 60.4M
- +2.51M (+4.3%) vs. Q3 2022
- Total value
- $2.38B
- +$291.8M (+14.0%) vs. Q3 2022
- New holders
- 22
- 60 more added
- Sold out
- 17
- 46 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Tri Locum Partners LP | 93,364 | $3.68M | 1.63% | −40,967−30.5% | Reduced |
| DnB Asset Management AS | 94,551 | $3.73M | 0.03% | +94,551 | New |
| Twinbeech Capital LP | 101,717 | $4.01M | 0.08% | +52,967+108.7% | Added |
| Swiss National Bank | 112,700 | $4.44M | 0.00% | +4,300+4.0% | Added |
| Nan Fung Group Holdings Ltd | 114,380 | $4.51M | 3.11% | 00.0% | Unchanged |
| Moore Capital Management, LP | 129,417 | $5.10M | 0.14% | +26,440+25.7% | Added |
| EAM Global Investors LLC | 146,387 | $5.77M | 1.49% | −8,098−5.2% | Reduced |
| Putnam Investments LLC | 152,660 | $6.02M | 0.01% | +23,376+18.1% | Added |
| Ikarian Capital, LLC | 160,486 | $6.33M | 2.63% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 162,828 | $6.42M | 0.02% | +15,473+10.5% | Added |
| Ensign Peak Advisors, Inc | 164,380 | $6.48M | 0.01% | +50,900+44.9% | Added |
| Schonfeld Strategic Advisors LLC | 168,413 | $6.64M | 0.06% | +60,129+55.5% | Added |
| AXA S.A. | 190,794 | $7.52M | 0.03% | −1,042−0.5% | Reduced |
| Vanguard Group Inc | 192,076 | $7.57M | 0.00% | +6,884+3.7% | Added |
| State Street Corp | 197,436 | $7.78M | 0.00% | +27,065+15.9% | Added |
| State of Wisconsin Investment Board | 217,620 | $8.58M | 0.03% | +146+0.1% | Added |
| Parkman Healthcare Partners LLC | 235,491 | $9.29M | 2.47% | +12,894+5.8% | Added |
| Nicholas Investment Partners, LP | 252,302 | $9.95M | 0.87% | +252,302 | New |
| Silverarc Capital Management, LLC | 253,655 | $10.0M | 3.44% | +7,663+3.1% | Added |
| Eversept Partners, LP | 275,704 | $10.9M | 1.03% | +16,092+6.2% | Added |
| Goldman Sachs Group Inc | 283,541 | $11.2M | 0.00% | −181,724−39.1% | Reduced |
| Janus Henderson Group PLC | 291,786 | $11.5M | 0.01% | +57,952+24.8% | Added |
| Woodline Partners LP | 298,440 | $11.8M | 0.16% | −105,919−26.2% | Reduced |
| Dimensional Fund Advisors LP | 314,673 | $12.4M | 0.00% | −27,358−8.0% | Reduced |
| DAFNA Capital Management LLC | 316,092 | $12.5M | 3.51% | −59,131−15.8% | Reduced |
| Granahan Investment Management Inc | 324,250 | $12.8M | 0.39% | +24,395+8.1% | Added |
| D. E. Shaw & Co., Inc. | 360,421 | $14.2M | 0.02% | −49,142−12.0% | Reduced |
| Bank of New York Mellon Corp | 388,360 | $15.3M | 0.00% | −49,285−11.3% | Reduced |
| TimesSquare Capital Management, LLC | 482,180 | $19.0M | 0.27% | +482,180 | New |
| Millennium Management LLC | 594,541 | $23.4M | 0.03% | +34,192+6.1% | Added |
| Boxer Capital, LLC | 600,000 | $23.7M | 1.27% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 641,200 | $25.3M | 0.50% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 677,165 | $26.7M | 0.05% | +677,165 | New |
| Adage Capital Partners GP, L.L.C. | 725,000 | $28.6M | 0.07% | +50,000+7.4% | Added |
| Candriam Luxembourg S.C.A. | 735,884 | $29.0M | 0.20% | −25,000−3.3% | Reduced |
| Baker Bros. Advisors LP | 751,639 | $29.6M | 0.18% | 00.0% | Unchanged |
| Great Point Partners LLC | 850,000 | $33.5M | 6.93% | 00.0% | Unchanged |
| Logos Global Management LP | 900,000 | $35.5M | 4.16% | +400,000+80.0% | Added |
| BlackRock Inc. | 925,623 | $36.5M | 0.00% | −116,906−11.2% | Reduced |
| OrbiMed Advisors LLC | 1,149,100 | $45.3M | 0.87% | +11,800+1.0% | Added |
| Citadel Advisors LLC | 1,164,407 | $45.9M | 0.05% | +22,405+2.0% | Added |
| Rock Springs Capital Management LP | 1,175,672 | $46.4M | 1.12% | +19,711+1.7% | Added |
| Point72 Asset Management, L.P. | 1,178,324 | $46.5M | 0.18% | −461,748−28.2% | Reduced |
| Holocene Advisors, LP | 1,191,638 | $47.0M | 0.29% | −637,514−34.9% | Reduced |
| Samlyn Capital, LLC | 1,193,814 | $47.1M | 0.92% | −95,419−7.4% | Reduced |
| BVF Inc | 1,271,243 | $50.1M | 2.12% | +370,148+41.1% | Added |
| Braidwell LP | 1,548,110 | $61.0M | 2.05% | +1,548,110 | New |
| Commodore Capital LP | 1,659,111 | $65.4M | 9.86% | +64,179+4.0% | Added |
| Perceptive Advisors LLC | 1,921,273 | $75.8M | 2.18% | −201,262−9.5% | Reduced |
| Capital International Investors | 2,099,579 | $82.8M | 0.02% | +457,071+27.8% | Added |
| Pictet Asset Management SA | 2,119,619 | $83.6M | 0.12% | −167,746−7.3% | Reduced |
| Lord, Abbett & Co. LLC | 2,124,009 | $83.7M | 0.30% | +210,148+11.0% | Added |
| Capital World Investors | 2,274,974 | $89.7M | 0.02% | 00.0% | Unchanged |
| Redmile Group, LLC | 2,360,414 | $93.1M | 3.81% | −10,200−0.4% | Reduced |
| Marshall Wace, LLP | 2,366,178 | $93.3M | 0.24% | −444,917−15.8% | Reduced |
| Polar Capital Holdings Plc | 3,045,874 | $120.1M | 0.96% | +383,152+14.4% | Added |
| Driehaus Capital Management LLC | 4,681,797 | $184.6M | 2.75% | +177,777+3.9% | Added |
| FMR LLC | 4,690,829 | $185.0M | 0.02% | +21,070+0.5% | Added |
| Avoro Capital Advisors LLC | 4,900,000 | $193.2M | 2.89% | 00.0% | Unchanged |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −272,500−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −55,974−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −54,208−100.0% | Sold out |
| Bridger Management, LLC | 0 | $0 | 0.00% | −45,235−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −45,143−100.0% | Sold out |
| Difesa Capital Management, LP | 0 | $0 | 0.00% | −24,500−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −15,927−100.0% | Sold out |
| Victory Capital Management Inc | 0 | $0 | 0.00% | −12,228−100.0% | Sold out |
| Oppenheimer & Co Inc | 0 | $0 | 0.00% | −11,113−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −10,605−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −9,990−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −7,263−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −5,603−100.0% | Sold out |
| Amundi | 0 | $0 | 0.00% | −3,581−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −1,300−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −132−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −432−100.0% | Sold out |