Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 346
- +27 vs. Q1 2026
- Shares held
- 75.9M
- −104.9K (−0.1%) vs. Q1 2026
- Total value
- $9.30B
- +$1.30B (+16.2%) vs. Q1 2026
- New holders
- 62
- 141 more added
- Sold out
- 35
- 90 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 208,900 | $25.6M | 0.59% | +49,200+30.8% | Added |
| SEB Asset Management AB | 209,963 | $25.7M | 0.10% | −22,453−9.7% | Reduced |
| Segall Bryant & Hamill, LLC | 214,724 | $26.3M | 0.31% | +2,010+0.9% | Added |
| NEXTBio Capital Management LP | 219,333 | $26.9M | 12.37% | −10,286−4.5% | Reduced |
| Eagle Health Investments LP | 248,322 | $30.4M | 5.05% | +69,000+38.5% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 259,972 | $31.9M | 0.03% | −46,065−15.1% | Reduced |
| Stephens Investment Management Group LLC | 281,832 | $34.5M | 0.37% | +281,832 | New |
| Nuveen, LLC | 284,085 | $34.8M | 0.01% | +156,171+122.1% | Added |
| 683 Capital Management, LLC | 290,000 | $35.5M | 3.27% | −65,000−18.3% | Reduced |
| BNP Paribas Arbitrage, SA | 301,472 | $37.0M | 0.02% | +106,942+55.0% | Added |
| Neuberger Berman Group LLC | 302,427 | $37.1M | 0.02% | +160,986+113.8% | Added |
| Bank of New York Mellon Corp | 358,300 | $43.9M | 0.01% | +16,835+4.9% | Added |
| Principal Financial Group Inc | 385,262 | $47.2M | 0.02% | +17,440+4.7% | Added |
| Lord, Abbett & Co. LLC | 398,994 | $48.9M | 0.14% | +235,535+144.1% | Added |
| Vanguard Fiduciary Trust Co | 437,747 | $53.7M | 0.01% | +25,017+6.1% | Added |
| Franklin Resources Inc | 520,032 | $63.7M | 0.01% | +382,161+277.2% | Added |
| Pictet Asset Management Holding SA | 567,990 | $69.6M | 0.07% | −13,093−2.3% | Reduced |
| Voya Investment Management LLC | 571,618 | $70.1M | 0.06% | +117,235+25.8% | Added |
| Charles Schwab Investment Management Inc | 583,774 | $71.6M | 0.01% | +30,818+5.6% | Added |
| American Century Companies Inc | 598,600 | $73.4M | 0.03% | +61,280+11.4% | Added |
| Northern Trust Corp | 666,105 | $81.7M | 0.01% | +78,137+13.3% | Added |
| FMR LLC | 672,186 | $82.4M | 0.00% | +10,189+1.5% | Added |
| Clearbridge Investments, LLC | 725,335 | $88.9M | 0.07% | +103,515+16.6% | Added |
| Driehaus Capital Management LLC | 731,053 | $89.6M | 0.52% | +10,125+1.4% | Added |
| Goldman Sachs Group Inc | 812,852 | $99.6M | 0.01% | +33,907+4.4% | Added |
| Hood River Capital Management LLC | 882,738 | $108.2M | 0.78% | +53,453+6.4% | Added |
| Alyeska Investment Group, L.P. | 889,298 | $109.0M | 0.28% | +296,101+49.9% | Added |
| Morgan Stanley | 905,992 | $111.1M | 0.01% | −112,230−11.0% | Reduced |
| ADAR1 Capital Management, LLC | 960,863 | $117.8M | 5.54% | −33,256−3.3% | Reduced |
| Perceptive Advisors LLC | 981,879 | $120.4M | 1.87% | −249,000−20.2% | Reduced |
| Jennison Associates LLC | 1,151,681 | $141.2M | 0.08% | +79,670+7.4% | Added |
| Bank of America Corp | 1,324,498 | $162.4M | 0.01% | +29,064+2.2% | Added |
| Woodline Partners LP | 1,414,173 | $173.3M | 0.54% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 1,741,209 | $213.5M | 0.01% | +71,838+4.3% | Added |
| Jupiter Topco LLC | 2,129,780 | $261.0M | 0.11% | +2,129,780 | New |
| Price T Rowe Associates Inc | 2,149,662 | $263.5M | 0.03% | +484,165+29.1% | Added |
| Invesco Ltd. | 2,340,667 | $286.9M | 0.02% | +175,997+8.1% | Added |
| Johnson & Johnson | 2,449,183 | $300.2M | 37.59% | 00.0% | Unchanged |
| Vanguard Capital Management LLC | 2,853,394 | $349.8M | 0.01% | +47,498+1.7% | Added |
| State Street Corp | 3,321,554 | $407.2M | 0.01% | +204,805+6.6% | Added |
| UBS Group AG | 3,399,221 | $416.7M | 0.07% | −1,778,575−34.4% | Reduced |
| Wellington Management Group LLP | 3,416,781 | $418.8M | 0.07% | −182,863−5.1% | Reduced |
| Vanguard Portfolio Management LLC | 3,629,298 | $444.9M | 0.02% | +148,087+4.3% | Added |
| RTW Investments, LP | 5,061,175 | $620.4M | 5.30% | +2,1220.0% | Added |
| Farallon Capital Management, L.L.C. | 6,348,906 | $778.2M | 4.56% | 00.0% | Unchanged |
| BlackRock, Inc. | 10,307,837 | $1.26B | 0.02% | +528,468+5.4% | Added |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −1,551,900−100.0% | Sold out |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 0 | $0 | 0.00% | −571,825−100.0% | Sold out |
| Rubric Capital Management LP | 0 | $0 | 0.00% | −427,998−100.0% | Sold out |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −326,159−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −282,436−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Royce & Associates LP | 0 | $0 | 0.00% | −14,349−100.0% | Sold out |
| Hussman Strategic Advisors, Inc. | 0 | $0 | 0.00% | −10,500−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −10,479−100.0% | Sold out |
| Advisors Asset Management, Inc. | 0 | $0 | 0.00% | −4,644−100.0% | Sold out |
| Cynosure Management, LLC | 0 | $0 | 0.00% | −4,635−100.0% | Sold out |
| Dymon Asia Capital (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −4,600−100.0% | Sold out |
| Vident Advisory, LLC | 0 | $0 | 0.00% | −4,481−100.0% | Sold out |
| Abacus Wealth Partners, LLC | 0 | $0 | 0.00% | −4,094−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −3,760−100.0% | Sold out |
| Headlands Technologies LLC | 0 | $0 | 0.00% | −2,957−100.0% | Sold out |
| Sumitomo Mitsui Trust Holdings, Inc. | 0 | $0 | 0.00% | −2,760−100.0% | Sold out |
| Vise Technologies, Inc. | 0 | $0 | 0.00% | −2,996−100.0% | Sold out |
| GTS Securities LLC | 0 | $0 | 0.00% | −2,416−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −2,012−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −1,429−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −1,001−100.0% | Sold out |
| CFG Wealth Management Services, Inc. | 0 | $0 | 0.00% | −611−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −349−100.0% | Sold out |
| Ameritas Advisory Services, LLC | 0 | $0 | 0.00% | −334−100.0% | Sold out |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −173−100.0% | Sold out |
| Sound Income Strategies, LLC | 0 | $0 | 0.00% | −156−100.0% | Sold out |
| Annis Gardner Whiting Capital Advisors, LLC | 0 | $0 | 0.00% | −76−100.0% | Sold out |
| MCF Advisors LLC | 0 | $0 | 0.00% | −40−100.0% | Sold out |
| Golden State Equity Partners | 0 | $0 | 0.00% | −27−100.0% | Sold out |
| Picton Mahoney Asset Management | 0 | $0 | 0.00% | −25−100.0% | Sold out |
| Pension & Wealth Management Advisors, Inc. | 0 | $0 | 0.00% | −20−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −18−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −14−100.0% | Sold out |
| Root Financial Partners, LLC | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| Janus Henderson Group PLC | – | – | – | – | Not filed |
| Skopos Labs, Inc. | – | – | – | – | Not filed |
| CWM, LLC | – | – | – | – | Not filed |