Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 346
- +27 vs. Q1 2026
- Shares held
- 75.9M
- −104.9K (−0.1%) vs. Q1 2026
- Total value
- $9.30B
- +$1.30B (+16.2%) vs. Q1 2026
- New holders
- 62
- 141 more added
- Sold out
- 35
- 90 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Bayforest Capital Ltd | 2,675 | $327.9K | 0.30% | +2,675 | New |
| Evergreen Capital Management LLC | 2,830 | $346.9K | 0.01% | +10+0.4% | Added |
| Norden Group LLC | 2,868 | $351.6K | 0.03% | +58+2.1% | Added |
| AE Wealth Management LLC | 2,875 | $352.4K | 0.00% | −13−0.5% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,876 | $352.5K | 0.00% | −452−13.6% | Reduced |
| Gabelli Funds LLC | 2,900 | $355.5K | 0.00% | −329−10.2% | Reduced |
| PSP Research LLC | 3,000 | $367.7K | 0.20% | 00.0% | Unchanged |
| Triglav Skladi, D.O.O. | 3,000 | $367.7K | 0.02% | +3,000 | New |
| State of Wyoming | 3,102 | $380.2K | 0.04% | +3,102 | New |
| GAMMA Investing LLC | 3,109 | $381.1K | 0.01% | +208+7.2% | Added |
| Pinnacle Wealth Planning Services, Inc. | 3,129 | $383.6K | 0.04% | −3−0.1% | Reduced |
| Simplex Trading, LLC | 3,149 | $386.0K | 0.01% | +3,149 | New |
| Burney Co | 3,179 | $389.7K | 0.01% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 3,287 | $399.8K | 0.01% | +492+17.6% | Added |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 3,298 | $404.3K | 0.12% | −6,036−64.7% | Reduced |
| Crossmark Global Holdings, Inc. | 3,389 | $415.4K | 0.01% | −100−2.9% | Reduced |
| Swiss Life Asset Management Ltd | 3,403 | $417.1K | 0.00% | +299+9.6% | Added |
| Royal Bank of Canada | 3,473 | $426.0K | 0.00% | +1,874+117.2% | Added |
| US Bancorp | 3,494 | $428.3K | 0.00% | −420−10.7% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 3,541 | $434.1K | 0.00% | +3,541 | New |
| Balyasny Asset Management LLC | 3,598 | $441.0K | 0.00% | −97,701−96.4% | Reduced |
| Velan Capital Investment Management LP | 3,700 | $453.5K | 0.28% | 00.0% | Unchanged |
| CAPROCK Group, Inc. | 3,712 | $455.0K | 0.01% | +3,712 | New |
| Vestcor Inc | 3,765 | $462.0K | 0.01% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 3,786 | $464.1K | 0.00% | −700−15.6% | Reduced |
| Himension Fund | 3,844 | $471.2K | 0.03% | +3,844 | New |
| XTX Topco Ltd | 3,868 | $474.1K | 0.01% | +3,868 | New |
| E Fund Management Co., Ltd. | 3,891 | $477.0K | 0.01% | −2,142−35.5% | Reduced |
| LPL Financial LLC | 3,946 | $483.7K | 0.00% | +1,153+41.3% | Added |
| M&T Bank Corp | 3,984 | $488.4K | 0.00% | +126+3.3% | Added |
| King Wealth | 4,000 | $490.0K | 0.05% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 4,191 | $513.7K | 0.00% | +389+10.2% | Added |
| Wealth Enhancement Advisory Services, LLC | 3,958 | $520.2K | 0.00% | +301+8.2% | Added |
| Abel Hall, LLC | 4,286 | $525.4K | 0.09% | +28+0.7% | Added |
| Engineers Gate Manager LP | 4,373 | $536.0K | 0.01% | +4,373 | New |
| The PNC Financial Services Group, Inc. | 4,458 | $546.5K | 0.00% | +460+11.5% | Added |
| O'Shaughnessy Asset Management, LLC | 4,488 | $550.1K | 0.00% | +2,048+83.9% | Added |
| Los Angeles Capital Management LLC | 4,727 | $579.4K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 4,738 | $580.8K | 0.00% | +1,963+70.7% | Added |
| Rockefeller Capital Management L.P. | 4,818 | $590.6K | 0.00% | −10−0.2% | Reduced |
| Jones Financial Companies LLLP | 4,934 | $601.4K | 0.00% | +2,011+68.8% | Added |
| Toroso Investments, LLC | 4,988 | $611.4K | 0.00% | −6,046−54.8% | Reduced |
| Keybank National Association | 4,997 | $612.5K | 0.00% | +711+16.6% | Added |
| Kestra Advisory Services, LLC | 5,061 | $620.4K | 0.00% | +7+0.1% | Added |
| CIBC Bancorp USA Inc. | 5,180 | $635.0K | 0.00% | +2,212+74.5% | Added |
| Quadrature Capital Ltd | 5,222 | $640.1K | 0.01% | +5,222 | New |
| TFB Advisors LLC | 5,235 | $641.7K | 0.28% | +3,044+138.9% | Added |
| HighTower Advisors, LLC | 5,308 | $650.7K | 0.00% | −78−1.4% | Reduced |
| Ameritas Investment Partners, Inc. | 5,586 | $684.7K | 0.02% | +861+18.2% | Added |
| CWM Advisors, LLC | 5,591 | $685.4K | 0.03% | +555+11.0% | Added |
| Panagora Asset Management Inc | 5,832 | $714.9K | 0.00% | −110,777−95.0% | Reduced |
| Teacher Retirement System of Texas | 5,967 | $731.4K | 0.00% | −481−7.5% | Reduced |
| JustInvest LLC | 5,978 | $732.8K | 0.01% | +306+5.4% | Added |
| Public Employees Retirement Association of Colorado | 6,001 | $736.0K | 0.00% | 00.0% | Unchanged |
| Xponance, Inc. | 6,062 | $743.1K | 0.00% | +590+10.8% | Added |
| Bank of Montreal | 6,147 | $753.5K | 0.00% | +390+6.8% | Added |
| Campbell & CO Investment Adviser LLC | 6,206 | $760.7K | 0.04% | +6,206 | New |
| Brinker Capital Investments, LLC | 6,428 | $787.9K | 0.01% | +21+0.3% | Added |
| Captrust Financial Advisors | 6,522 | $799.5K | 0.00% | +4,620+242.9% | Added |
| Cerity Partners LLC | 6,563 | $804.5K | 0.00% | +870+15.3% | Added |
| Fred Alger Management, LLC | 7,650 | $937.7K | 0.00% | +7,650 | New |
| Amundi | 7,692 | $942.9K | 0.00% | +3,579+87.0% | Added |
| Natixis | 7,776 | $953.2K | 0.00% | +7,776 | New |
| Cambria Investment Management, L.P. | 7,869 | $964.6K | 0.05% | +1,004+14.6% | Added |
| Virtu Financial LLC | 8,163 | $1.00M | 0.03% | +8,163 | New |
| Quantinno Capital Management LP | 8,176 | $1.00M | 0.00% | +1,739+27.0% | Added |
| Holocene Advisors, LP | 8,495 | $1.04M | 0.00% | −201,421−96.0% | Reduced |
| Maryland State Retirement & Pension System | 8,792 | $1.08M | 0.02% | +225+2.6% | Added |
| AlphaCentric Advisors LLC | 9,171 | $1.12M | 0.95% | +131+1.4% | Added |
| Bridgewater Associates, LP | 9,269 | $1.14M | 0.00% | +3,993+75.7% | Added |
| J. Goldman & Co LP | 9,414 | $1.15M | 0.04% | −300−3.1% | Reduced |
| Allianz Asset Management GmbH | 9,600 | $1.18M | 0.00% | 00.0% | Unchanged |
| Cache Advisors, LLC | 10,143 | $1.24M | 0.11% | 00.0% | Unchanged |
| Verition Fund Management LLC | 10,143 | $1.24M | 0.01% | +10,143 | New |
| Virtus Investment Advisers, Inc. | 10,593 | $1.30M | 0.30% | +7,733+270.4% | Added |
| ProShare Advisors LLC | 10,878 | $1.33M | 0.00% | −1,040−8.7% | Reduced |
| Winton Group Ltd | 10,884 | $1.33M | 0.04% | −1,789−14.1% | Reduced |
| Virginia Retirement Systems Et Al | 11,200 | $1.37M | 0.01% | −1,800−13.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 11,485 | $1.41M | 0.08% | −3,438−23.0% | Reduced |
| KLP Kapitalforvaltning AS | 11,600 | $1.42M | 0.00% | +600+5.5% | Added |
| Barclays PLC | 11,810 | $1.45M | 0.00% | −2,595−18.0% | Reduced |
| Colony Group, LLC | 11,878 | $1.46M | 0.00% | +11,878 | New |
| Calamos Advisors LLC | 11,931 | $1.46M | 0.01% | −11,542−49.2% | Reduced |
| Aquatic Capital Management LLC | 12,180 | $1.49M | 0.05% | +12,180 | New |
| Bleakley Financial Group, LLC | 12,538 | $1.54M | 0.02% | −264−2.1% | Reduced |
| Vanguard Investments Australia, Ltd. | 12,655 | $1.55M | 0.00% | +525+4.3% | Added |
| Franklin Street Advisors Inc | 12,810 | $1.57M | 0.09% | +1,725+15.6% | Added |
| Jackson Creek Investment Advisors LLC | 11,610 | $1.59M | 0.53% | +11,610 | New |
| AQR Capital Management LLC | 13,096 | $1.61M | 0.00% | +1,222+10.3% | Added |
| Fifth Third Bancorp | 13,112 | $1.61M | 0.00% | −90−0.7% | Reduced |
| Glenmede Trust Co NA | 13,387 | $1.64M | 0.01% | +4,152+45.0% | Added |
| Oregon Public Employees Retirement Fund | 13,694 | $1.68M | 0.02% | +238+1.8% | Added |
| Arizona State Retirement System | 14,085 | $1.73M | 0.01% | +347+2.5% | Added |
| Weiss Asset Management LP | 14,209 | $1.74M | 0.02% | +4,429+45.3% | Added |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 14,335 | $1.76M | 0.01% | −197−1.4% | Reduced |
| STRS Ohio | 15,100 | $1.85M | 0.01% | −300−1.9% | Reduced |
| Bamco Inc | 16,000 | $1.96M | 0.00% | +1,000+6.7% | Added |
| Profund Advisors LLC | 16,118 | $1.98M | 0.05% | −6,749−29.5% | Reduced |
| Amalgamated Bank | 16,268 | $1.99M | 0.01% | −584−3.5% | Reduced |
| StemPoint Capital LP | 16,303 | $2.00M | 0.35% | −56,274−77.5% | Reduced |