Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 274
- +3 vs. Q1 2025
- Shares held
- 71.0M
- +5.66M (+8.7%) vs. Q1 2025
- Total value
- $3.92B
- +$774.8M (+24.6%) vs. Q1 2025
- New holders
- 52
- 120 more added
- Sold out
- 49
- 76 more reduced
4 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wells Fargo & Company | 41,687 | $2.30M | 0.00% | +1,878+4.7% | Added |
| State of New Jersey Common Pension Fund D | 41,025 | $2.27M | 0.01% | −12,711−23.7% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 40,484 | $2.24M | 0.00% | +36,288+864.8% | Added |
| Alps Advisors Inc | 40,220 | $2.22M | 0.01% | −12,754−24.1% | Reduced |
| Gotham Asset Management, LLC | 37,287 | $2.06M | 0.01% | +14,215+61.6% | Added |
| State of Alaska, Department of Revenue | 36,906 | $2.04M | 0.02% | +3,883+11.8% | Added |
| Trexquant Investment LP | 36,018 | $1.99M | 0.02% | −67,965−65.4% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 35,841 | $1.98M | 0.00% | −1,562−4.2% | Reduced |
| J. Goldman & Co LP | 35,828 | $1.98M | 0.06% | −29,416−45.1% | Reduced |
| MetLife Investment Management | 34,770 | $1.92M | 0.01% | −20−0.1% | Reduced |
| Man Group plc | 34,013 | $1.88M | 0.00% | −94,593−73.6% | Reduced |
| Intech Investment Management LLC | 33,953 | $1.88M | 0.02% | +2,971+9.6% | Added |
| State of Wisconsin Investment Board | 32,988 | $1.82M | 0.00% | −20,752−38.6% | Reduced |
| Massachusetts Financial Services Co | 32,123 | $1.78M | 0.00% | +397+1.3% | Added |
| Hussman Strategic Advisors, Inc. | 31,500 | $1.74M | 0.40% | −21,000−40.0% | Reduced |
| Creative Planning | 30,204 | $1.67M | 0.00% | +12,871+74.3% | Added |
| Louisiana State Employees Retirement System | 29,000 | $1.60M | 0.03% | +900+3.2% | Added |
| Illinois Municipal Retirement Fund | 27,569 | $1.52M | 0.02% | +8,060+41.3% | Added |
| Citadel Advisors LLC | 27,201 | $1.50M | 0.00% | −126,866−82.3% | Reduced |
| Brevan Howard Capital Management LP | 26,994 | $1.49M | 0.02% | +10,880+67.5% | Added |
| State of Tennessee, Treasury Department | 25,990 | $1.44M | 0.01% | −495−1.9% | Reduced |
| Envestnet Asset Management Inc | 23,878 | $1.32M | 0.00% | +7,199+43.2% | Added |
| Toroso Investments, LLC | 23,777 | $1.31M | 0.01% | +4,367+22.5% | Added |
| Yousif Capital Management, LLC | 23,404 | $1.29M | 0.01% | +1,067+4.8% | Added |
| Ensign Peak Advisors, Inc | 23,136 | $1.28M | 0.00% | −3,900−14.4% | Reduced |
| Artia Global Partners LP | 22,951 | $1.27M | 0.33% | −310,900−93.1% | Reduced |
| Horizon Investments, LLC | 22,470 | $1.24M | 0.02% | +22,470 | New |
| Mackenzie Financial Corp | 22,457 | $1.24M | 0.00% | −241−1.1% | Reduced |
| Allianz Asset Management GmbH | 22,300 | $1.23M | 0.00% | +15,900+248.4% | Added |
| Glenmede Investment Management, LP | 21,434 | $1.18M | 0.01% | +21,434 | New |
| Comerica Bank | 21,291 | $1.18M | 0.00% | +1,050+5.2% | Added |
| Fieldview Capital Management, LLC | 20,381 | $1.13M | 0.17% | +20,381 | New |
| STRS Ohio | 19,600 | $1.08M | 0.00% | +600+3.2% | Added |
| New York State Common Retirement Fund | 19,582 | $1.08M | 0.00% | 00.0% | Unchanged |
| Bellevue Group AG | 19,472 | $1.08M | 0.02% | +1,850+10.5% | Added |
| Guggenheim Capital LLC | 19,208 | $1.06M | 0.01% | +303+1.6% | Added |
| Profund Advisors LLC | 19,074 | $1.05M | 0.04% | +7,515+65.0% | Added |
| Virginia Retirement Systems Et Al | 19,000 | $1.05M | 0.01% | +1,400+8.0% | Added |
| China Universal Asset Management Co., Ltd. | 18,908 | $1.05M | 0.10% | +136+0.7% | Added |
| Teachers Retirement System of the State of Kentucky | 18,732 | $1.04M | 0.01% | −1,468−7.3% | Reduced |
| Maryland State Retirement & Pension System | 18,216 | $1.01M | 0.02% | +818+4.7% | Added |
| Arrowstreet Capital, Limited Partnership | 17,856 | $986.9K | 0.00% | +17,856 | New |
| Amalgamated Bank | 17,543 | $970.0K | 0.01% | +605+3.6% | Added |
| Persistent Asset Partners Ltd | 17,520 | $968.3K | 0.85% | +17,520 | New |
| Winton Group Ltd | 17,433 | $963.5K | 0.05% | −3,362−16.2% | Reduced |
| AQR Capital Management LLC | 17,409 | $962.2K | 0.00% | −22,678−56.6% | Reduced |
| Handelsbanken Fonder AB | 17,000 | $940.0K | 0.00% | +2,600+18.1% | Added |
| StemPoint Capital LP | 16,770 | $926.8K | 0.30% | −32,471−65.9% | Reduced |
| State Board of Administration of Florida Retirement System | 16,303 | $901.1K | 0.00% | 00.0% | Unchanged |
| Polen Capital Management LLC | 15,999 | $884.3K | 0.00% | +15,999 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 15,913 | $879.5K | 0.00% | +1,651+11.6% | Added |
| DekaBank Deutsche Girozentrale | 15,800 | $879.0K | 0.00% | 00.0% | Unchanged |
| Moran Wealth Management, LLC | 15,761 | $871.1K | 0.03% | −134−0.8% | Reduced |
| Mariner, LLC | 15,701 | $867.8K | 0.00% | −930−5.6% | Reduced |
| ProShare Advisors LLC | 15,376 | $849.8K | 0.00% | −1,382−8.2% | Reduced |
| Millennium Management LLC | 15,191 | $839.6K | 0.00% | −119,078−88.7% | Reduced |
| UBS Oconnor LLC | 14,523 | $802.7K | 0.02% | +1,183+8.9% | Added |
| Precision Wealth Strategies, LLC | 14,339 | $792.5K | 0.26% | +14,339 | New |
| Arizona State Retirement System | 14,326 | $791.8K | 0.00% | +1,525+11.9% | Added |
| Oregon Public Employees Retirement Fund | 14,200 | $784.8K | 0.01% | +500+3.6% | Added |
| Erste Asset Management GmbH | 13,500 | $751.8K | 0.01% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 13,456 | $743.7K | 0.01% | +528+4.1% | Added |
| Natixis Advisors, L.P. | 13,442 | $743.0K | 0.00% | +13,442 | New |
| Teacher Retirement System of Texas | 13,205 | $729.8K | 0.00% | +1,180+9.8% | Added |
| Algert Global LLC | 13,055 | $721.5K | 0.02% | −5,610−30.1% | Reduced |
| Harvest Investment Services, LLC | 13,029 | $720.1K | 0.16% | −2,882−18.1% | Reduced |
| Royce & Associates LP | 12,255 | $677.3K | 0.01% | 00.0% | Unchanged |
| Franklin Street Advisors Inc | 11,300 | $625.0K | 0.04% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 10,400 | $574.8K | 0.00% | +1,700+19.5% | Added |
| Options Solutions, LLC | 10,226 | $565.2K | 0.20% | +10,226 | New |
| Cache Advisors, LLC | 10,143 | $560.6K | 0.15% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,073 | $556.7K | 0.00% | +981+10.8% | Added |
| HighTower Advisors, LLC | 9,980 | $551.6K | 0.00% | +3,462+53.1% | Added |
| Cerity Partners LLC | 9,722 | $537.3K | 0.00% | +477+5.2% | Added |
| Bank of Montreal | 9,578 | $533.4K | 0.00% | +642+7.2% | Added |
| Simplex Trading, LLC | 9,452 | $522.0K | 0.01% | −16,482−63.6% | Reduced |
| Aviva PLC | 9,435 | $521.5K | 0.00% | −3,765−28.5% | Reduced |
| BNP Paribas Arbitrage, SA | 9,139 | $505.1K | 0.00% | −5,030−35.5% | Reduced |
| E Fund Management Co., Ltd. | 8,990 | $496.9K | 0.02% | +4,853+117.3% | Added |
| Cambria Investment Management, L.P. | 8,757 | $484.0K | 0.03% | −243−2.7% | Reduced |
| Pathstone Holdings, LLC | 8,195 | $453.0K | 0.00% | +8,195 | New |
| Mutual of America Capital Management LLC | 7,962 | $440.1K | 0.00% | −717−8.3% | Reduced |
| Palumbo Wealth Management LLC | 7,530 | $416.2K | 0.13% | +7,530 | New |
| Nomura Holdings Inc | 7,416 | $409.9K | 0.00% | +7,416 | New |
| XTX Topco Ltd | 7,332 | $405.2K | 0.02% | −6,925−48.6% | Reduced |
| CWM Advisors, LLC | 7,284 | $402.6K | 0.04% | −14,550−66.6% | Reduced |
| New Vernon Capital Holdings II LLC | 7,198 | $397.8K | 0.19% | −340,897−97.9% | Reduced |
| CIBC World Markets Corp | 7,173 | $396.5K | 0.00% | −6,005−45.6% | Reduced |
| Capstone Investment Advisors, LLC | 6,987 | $386.2K | 0.00% | +6,987 | New |
| Advantage Alpha Capital Partners LP | 6,972 | $385.3K | 0.10% | −1,662−19.2% | Reduced |
| Brinker Capital Investments, LLC | 6,600 | $364.8K | 0.00% | −131−1.9% | Reduced |
| Burney Co | 6,318 | $349.2K | 0.01% | −195,667−96.9% | Reduced |
| Bryce Point Capital, LLC | 6,200 | $342.7K | 0.29% | +6,200 | New |
| King Wealth | 6,000 | $332.0K | 0.05% | 00.0% | Unchanged |
| Mitsubishi UFJ Trust & Banking Corp | 5,975 | $330.2K | 0.00% | +5,975 | New |
| Ameritas Investment Partners, Inc. | 5,912 | $326.8K | 0.01% | 00.0% | Unchanged |
| Net Worth Advisory Group | 5,822 | $321.8K | 0.07% | +5,822 | New |
| Kestra Advisory Services, LLC | 5,763 | $318.5K | 0.00% | +582+11.2% | Added |
| Tower Research Capital LLC (TRC) | 5,339 | $295.1K | 0.01% | +5,108+2,211.3% | Added |
| US Bancorp | 5,223 | $288.7K | 0.00% | +1,569+42.9% | Added |