Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 274
- +3 vs. Q1 2025
- Shares held
- 71.0M
- +5.66M (+8.7%) vs. Q1 2025
- Total value
- $3.92B
- +$774.8M (+24.6%) vs. Q1 2025
- New holders
- 52
- 120 more added
- Sold out
- 49
- 76 more reduced
4 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| DecisionPoint Financial, LLC | 4 | $201 | 0.00% | +4 | New |
| Abound Wealth Management | 4 | $222 | 0.00% | 00.0% | Unchanged |
| Kilter Group LLC | 4 | $222 | 0.00% | +4 | New |
| UMA Financial Services, Inc. | 9 | $498 | 0.00% | +9 | New |
| Picton Mahoney Asset Management | 25 | $1.00K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 20 | $1.11K | 0.00% | +20 | New |
| Atlantic Trust, LLC | 21 | $1.16K | 0.00% | +21 | New |
| Whipplewood Advisors, LLC | 22 | $1.22K | 0.00% | +22 | New |
| Bare Financial Services, Inc | 23 | $1.27K | 0.00% | +23 | New |
| Larson Financial Group LLC | 26 | $1.44K | 0.00% | −100−79.4% | Reduced |
| Versant Capital Management, Inc | 29 | $1.60K | 0.00% | +29 | New |
| Farmers & Merchants Investments Inc | 35 | $1.93K | 0.00% | 00.0% | Unchanged |
| Wolff Wiese Magana LLC | 35 | $1.94K | 0.00% | 00.0% | Unchanged |
| Principal Securities, Inc. | 36 | $1.99K | 0.00% | +24+200.0% | Added |
| Huntington National Bank | 39 | $2.15K | 0.00% | +39 | New |
| Caitong International Asset Management Co., Ltd | 41 | $2.27K | 0.00% | −2,747−98.5% | Reduced |
| Parkside Financial Bank & Trust | 45 | $2.49K | 0.00% | +11+32.4% | Added |
| Geneos Wealth Management Inc. | 47 | $2.60K | 0.00% | +35+291.7% | Added |
| Kestra Investment Management, LLC | 54 | $2.80K | 0.00% | +27+100.0% | Added |
| IFP Advisors, Inc | 0 | $3.10K | 0.00% | 0 | New |
| Raffa Wealth Management, LLC | 60 | $3.32K | 0.00% | +60 | New |
| Riggs Asset Managment Co. Inc. | 71 | $3.92K | 0.00% | +71 | New |
| Annis Gardner Whiting Capital Advisors, LLC | 76 | $4.20K | 0.00% | +76 | New |
| WPG Advisers, LLC | 78 | $4.31K | 0.00% | +70+875.0% | Added |
| Bell Investment Advisors, Inc | 81 | $4.48K | 0.00% | +50+161.3% | Added |
| Brown Brothers Harriman & Co | 81 | $4.48K | 0.00% | +81 | New |
| MAI Capital Management | 86 | $4.75K | 0.00% | +86 | New |
| Farther Finance Advisors, LLC | 93 | $5.14K | 0.00% | −296−76.1% | Reduced |
| Parallel Advisors, LLC | 97 | $5.36K | 0.00% | +70+259.3% | Added |
| Danske Bank A/S | 100 | $5.53K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 110 | $6.08K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 110 | $6.08K | 0.00% | +15+15.8% | Added |
| Allworth Financial LP | 117 | $6.47K | 0.00% | +87+290.0% | Added |
| Massmutual Trust Co FSB | 119 | $6.58K | 0.00% | +74+164.4% | Added |
| Russell Investments Group, Ltd. | 129 | $7.13K | 0.00% | −3,229−96.2% | Reduced |
| Sterling Capital Management LLC | 143 | $7.90K | 0.00% | +80+127.0% | Added |
| Hantz Financial Services, Inc. | 143 | $8.00K | 0.00% | +141+7,050.0% | Added |
| Signaturefd, LLC | 149 | $8.23K | 0.00% | +55+58.5% | Added |
| Twin Peaks Wealth Advisors, LLC | 171 | $9.32K | 0.00% | +171 | New |
| Umb Bank N A | 199 | $11.0K | 0.00% | +41+25.9% | Added |
| Fifth Third Bancorp | 211 | $11.7K | 0.00% | −71−25.2% | Reduced |
| Daiwa Securities Group Inc. | 215 | $12.0K | 0.00% | 00.0% | Unchanged |
| Rise Advisors, LLC | 224 | $12.4K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 226 | $12.5K | 0.00% | +137+153.9% | Added |
| Assetmark, Inc | 290 | $16.0K | 0.00% | −5−1.7% | Reduced |
| Global Retirement Partners, LLC | 316 | $17.5K | 0.00% | +316 | New |
| Skopos Labs, Inc. | 487 | $26.9K | 0.00% | −913−65.2% | Reduced |
| FNY Investment Advisers, LLC | 500 | $27.0K | 0.01% | +500 | New |
| Bessemer Group Inc | 504 | $28.0K | 0.00% | +318+171.0% | Added |
| CWM, LLC | 609 | $34.0K | 0.00% | +407+201.5% | Added |
| Truvestments Capital LLC | 650 | $35.9K | 0.01% | +369+131.3% | Added |
| GAMMA Investing LLC | 1,077 | $59.5K | 0.00% | −126−10.5% | Reduced |
| Advisor Group Holdings, Inc. | 1,185 | $65.5K | 0.00% | +525+79.5% | Added |
| Smartleaf Asset Management LLC | 1,257 | $70.0K | 0.01% | +46+3.8% | Added |
| GF Fund Management Co. Ltd. | 1,526 | $84.3K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 1,574 | $87.0K | 0.00% | −519−24.8% | Reduced |
| Virtus Investment Advisers, Inc. | 1,670 | $92.3K | 0.03% | −2,395−58.9% | Reduced |
| Covestor Ltd | 1,745 | $97.0K | 0.06% | −342−16.4% | Reduced |
| SG Americas Securities, LLC | 1,924 | $106.0K | 0.00% | +1,924 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,394 | $132.3K | 0.00% | +340+16.6% | Added |
| The PNC Financial Services Group, Inc. | 2,414 | $133.4K | 0.00% | +422+21.2% | Added |
| NBC Securities, Inc. | 2,565 | $141.0K | 0.01% | +2,565 | New |
| Wexford Capital LP | 3,315 | $183.2K | 0.05% | +3,315 | New |
| Velan Capital Investment Management LP | 3,700 | $204.5K | 0.20% | +3,700 | New |
| Nisa Investment Advisors, LLC | 3,903 | $215.7K | 0.00% | +1,071+37.8% | Added |
| State of Wyoming | 3,985 | $220.3K | 0.03% | +2,528+173.5% | Added |
| Crossmark Global Holdings, Inc. | 4,065 | $224.7K | 0.00% | +4,065 | New |
| HSBC Holdings PLC | 4,340 | $242.1K | 0.00% | −4,118−48.7% | Reduced |
| Xponance, Inc. | 4,506 | $249.0K | 0.00% | +42+0.9% | Added |
| Bridgefront Capital, LLC | 4,545 | $251.2K | 0.07% | +4,545 | New |
| Advisors Asset Management, Inc. | 4,724 | $261.1K | 0.00% | +3+0.1% | Added |
| LPL Financial LLC | 4,818 | $266.3K | 0.00% | −70−1.4% | Reduced |
| Graham Capital Management, L.P. | 4,979 | $275.2K | 0.01% | +4,979 | New |
| Cornerstone Investment Partners, LLC | 4,980 | $275.2K | 0.01% | +3+0.1% | Added |
| US Bancorp | 5,223 | $288.7K | 0.00% | +1,569+42.9% | Added |
| Tower Research Capital LLC (TRC) | 5,339 | $295.1K | 0.01% | +5,108+2,211.3% | Added |
| Kestra Advisory Services, LLC | 5,763 | $318.5K | 0.00% | +582+11.2% | Added |
| Net Worth Advisory Group | 5,822 | $321.8K | 0.07% | +5,822 | New |
| Ameritas Investment Partners, Inc. | 5,912 | $326.8K | 0.01% | 00.0% | Unchanged |
| Mitsubishi UFJ Trust & Banking Corp | 5,975 | $330.2K | 0.00% | +5,975 | New |
| King Wealth | 6,000 | $332.0K | 0.05% | 00.0% | Unchanged |
| Bryce Point Capital, LLC | 6,200 | $342.7K | 0.29% | +6,200 | New |
| Burney Co | 6,318 | $349.2K | 0.01% | −195,667−96.9% | Reduced |
| Brinker Capital Investments, LLC | 6,600 | $364.8K | 0.00% | −131−1.9% | Reduced |
| Advantage Alpha Capital Partners LP | 6,972 | $385.3K | 0.10% | −1,662−19.2% | Reduced |
| Capstone Investment Advisors, LLC | 6,987 | $386.2K | 0.00% | +6,987 | New |
| CIBC World Markets Corp | 7,173 | $396.5K | 0.00% | −6,005−45.6% | Reduced |
| New Vernon Capital Holdings II LLC | 7,198 | $397.8K | 0.19% | −340,897−97.9% | Reduced |
| CWM Advisors, LLC | 7,284 | $402.6K | 0.04% | −14,550−66.6% | Reduced |
| XTX Topco Ltd | 7,332 | $405.2K | 0.02% | −6,925−48.6% | Reduced |
| Nomura Holdings Inc | 7,416 | $409.9K | 0.00% | +7,416 | New |
| Palumbo Wealth Management LLC | 7,530 | $416.2K | 0.13% | +7,530 | New |
| Mutual of America Capital Management LLC | 7,962 | $440.1K | 0.00% | −717−8.3% | Reduced |
| Pathstone Holdings, LLC | 8,195 | $453.0K | 0.00% | +8,195 | New |
| Cambria Investment Management, L.P. | 8,757 | $484.0K | 0.03% | −243−2.7% | Reduced |
| E Fund Management Co., Ltd. | 8,990 | $496.9K | 0.02% | +4,853+117.3% | Added |
| BNP Paribas Arbitrage, SA | 9,139 | $505.1K | 0.00% | −5,030−35.5% | Reduced |
| Aviva PLC | 9,435 | $521.5K | 0.00% | −3,765−28.5% | Reduced |
| Simplex Trading, LLC | 9,452 | $522.0K | 0.01% | −16,482−63.6% | Reduced |
| Bank of Montreal | 9,578 | $533.4K | 0.00% | +642+7.2% | Added |