Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- +38 vs. Q4 2024
- Shares held
- 65.3M
- +2.28M (+3.6%) vs. Q4 2024
- Total value
- $3.15B
- +$716.0M (+29.4%) vs. Q4 2024
- New holders
- 72
- 86 more added
- Sold out
- 34
- 90 more reduced
4 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Hantz Financial Services, Inc. | 2 | $0 | 0.00% | +2 | New |
| TFC Financial Management | 1 | $49 | 0.00% | +1 | New |
| Abound Wealth Management | 4 | $194 | 0.00% | 00.0% | Unchanged |
| WPG Advisers, LLC | 8 | $387 | 0.00% | +8 | New |
| Principal Securities, Inc. | 12 | $463 | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 11 | $532 | 0.00% | +11 | New |
| Geneos Wealth Management Inc. | 12 | $580 | 0.00% | +12 | New |
| Creative Financial Designs Inc | 20 | $967 | 0.00% | +20 | New |
| Stephens Consulting, LLC | 20 | $968 | 0.00% | +20 | New |
| Picton Mahoney Asset Management | 25 | $1.00K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 27 | $1.31K | 0.00% | 00.0% | Unchanged |
| Kestra Investment Management, LLC | 27 | $1.31K | 0.00% | +27 | New |
| Allworth Financial LP | 30 | $1.35K | 0.00% | +30 | New |
| Bell Investment Advisors, Inc | 31 | $1.50K | 0.00% | +14+82.4% | Added |
| Parkside Financial Bank & Trust | 34 | $1.65K | 0.00% | +30+750.0% | Added |
| Farmers & Merchants Investments Inc | 35 | $1.69K | 0.00% | 00.0% | Unchanged |
| Wolff Wiese Magana LLC | 35 | $1.69K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 45 | $2.18K | 0.00% | −6−11.8% | Reduced |
| Sterling Capital Management LLC | 63 | $3.05K | 0.00% | +3+5.0% | Added |
| CoreCap Advisors, LLC | 71 | $3.43K | 0.00% | −5−6.6% | Reduced |
| EverSource Wealth Advisors, LLC | 89 | $4.30K | 0.00% | +79+790.0% | Added |
| Signaturefd, LLC | 94 | $4.55K | 0.00% | +94 | New |
| Rothschild Investment LLC | 95 | $4.59K | 0.00% | +50+111.1% | Added |
| Coldstream Capital Management Inc | 99 | $4.79K | 0.00% | +99 | New |
| Danske Bank A/S | 100 | $4.84K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 110 | $5.32K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 126 | $6.09K | 0.00% | +111+740.0% | Added |
| Lindbrook Capital, LLC | 143 | $6.92K | 0.00% | +77+116.7% | Added |
| Umb Bank N A | 158 | $7.64K | 0.00% | −5−3.1% | Reduced |
| Bessemer Group Inc | 186 | $9.00K | 0.00% | −15−7.5% | Reduced |
| CWM, LLC | 202 | $10.0K | 0.00% | −184−47.7% | Reduced |
| Daiwa Securities Group Inc. | 215 | $10.0K | 0.00% | 00.0% | Unchanged |
| Rise Advisors, LLC | 224 | $10.8K | 0.00% | +224 | New |
| Tower Research Capital LLC (TRC) | 231 | $11.2K | 0.00% | −7,138−96.9% | Reduced |
| Boston Private Wealth LLC | 261 | $12.6K | 0.00% | +261 | New |
| Truvestments Capital LLC | 281 | $13.6K | 0.00% | +150+114.5% | Added |
| Fifth Third Bancorp | 282 | $13.6K | 0.00% | +190+206.5% | Added |
| Macquarie Group Ltd | 283 | $13.7K | 0.00% | +283 | New |
| Assetmark, Inc | 295 | $14.3K | 0.00% | +50+20.4% | Added |
| Farther Finance Advisors, LLC | 389 | $18.2K | 0.00% | +345+784.1% | Added |
| Advisor Group Holdings, Inc. | 660 | $31.9K | 0.00% | +68+11.5% | Added |
| GAMMA Investing LLC | 1,203 | $58.2K | 0.00% | +728+153.3% | Added |
| Smartleaf Asset Management LLC | 1,211 | $59.2K | 0.01% | +710+141.7% | Added |
| Aster Capital Management (DIFC) Ltd | 1,617 | $60.8K | 0.01% | +1,617 | New |
| Skopos Labs, Inc. | 1,400 | $67.7K | 0.01% | +1,400 | New |
| State of Wyoming | 1,457 | $70.5K | 0.01% | −6,375−81.4% | Reduced |
| GF Fund Management Co. Ltd. | 1,526 | $73.8K | 0.00% | +275+22.0% | Added |
| Amundi | 2,058 | $95.7K | 0.00% | +25+1.2% | Added |
| The PNC Financial Services Group, Inc. | 1,992 | $96.3K | 0.00% | +551+38.2% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,054 | $100.4K | 0.00% | +68+3.4% | Added |
| KBC Group NV | 2,093 | $101.0K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 2,087 | $101.0K | 0.07% | +444+27.0% | Added |
| Penserra Capital Management LLC | 2,429 | $117.0K | 0.00% | +2,429 | New |
| Quest Partners LLC | 2,704 | $130.8K | 0.01% | +527+24.2% | Added |
| Caitong International Asset Management Co., Ltd | 2,788 | $134.8K | 0.10% | +2,788 | New |
| Nisa Investment Advisors, LLC | 2,832 | $137.0K | 0.00% | −301−9.6% | Reduced |
| Acadian Asset Management LLC | 3,026 | $146.0K | 0.00% | −2,863−48.6% | Reduced |
| Quadrant Capital Group LLC | 3,278 | $158.5K | 0.01% | +3,278 | New |
| Russell Investments Group, Ltd. | 3,358 | $162.4K | 0.00% | +3,329+11,479.3% | Added |
| US Bancorp | 3,654 | $176.7K | 0.00% | +1,524+71.5% | Added |
| Virtus Investment Advisers, Inc. | 4,065 | $196.6K | 0.05% | +4,065 | New |
| Virtu Financial LLC | 4,140 | $200.0K | 0.01% | +4,140 | New |
| E Fund Management Co., Ltd. | 4,137 | $200.1K | 0.01% | −71,950−94.6% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 4,196 | $202.9K | 0.00% | +4,196 | New |
| Xponance, Inc. | 4,464 | $215.9K | 0.00% | +4,464 | New |
| Advisors Asset Management, Inc. | 4,721 | $228.3K | 0.00% | +2,123+81.7% | Added |
| LPL Financial LLC | 4,888 | $236.4K | 0.00% | +4,888 | New |
| Cornerstone Investment Partners, LLC | 4,977 | $240.7K | 0.01% | −439−8.1% | Reduced |
| Kestra Advisory Services, LLC | 5,181 | $250.6K | 0.00% | −466−8.3% | Reduced |
| Two Sigma Investments, LP | 5,741 | $277.6K | 0.00% | +83+1.5% | Added |
| CAPROCK Group, Inc. | 5,890 | $284.8K | 0.01% | +88+1.5% | Added |
| SummitTX Capital, L.P. | 5,900 | $285.3K | 0.01% | +5,900 | New |
| Ameritas Investment Partners, Inc. | 5,912 | $285.9K | 0.01% | 00.0% | Unchanged |
| King Wealth | 6,000 | $290.0K | 0.04% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 6,400 | $309.5K | 0.00% | −4,600−41.8% | Reduced |
| HighTower Advisors, LLC | 6,518 | $315.2K | 0.00% | +6,518 | New |
| Brinker Capital Investments, LLC | 6,731 | $325.5K | 0.00% | +6,731 | New |
| Orion Portfolio Solutions, LLC | 6,731 | $325.5K | 0.00% | +6,731 | New |
| Fred Alger Management, LLC | 7,477 | $361.6K | 0.00% | +7,477 | New |
| Capula Management Ltd | 7,684 | $371.6K | 0.00% | +7,684 | New |
| Landscape Capital Management, L.L.C. | 7,758 | $375.2K | 0.03% | +7,758 | New |
| Occudo Quantitative Strategies LP | 8,281 | $404.8K | 0.05% | +8,281 | New |
| HSBC Holdings PLC | 8,458 | $404.9K | 0.00% | +330+4.1% | Added |
| Advantage Alpha Capital Partners LP | 8,634 | $417.5K | 0.10% | +2,892+50.4% | Added |
| Mutual of America Capital Management LLC | 8,679 | $419.7K | 0.00% | −348−3.9% | Reduced |
| KLP Kapitalforvaltning AS | 8,700 | $420.7K | 0.00% | 00.0% | Unchanged |
| Quantessence Capital LLC | 8,900 | $430.4K | 0.11% | +8,900 | New |
| Bank of Montreal | 8,936 | $432.1K | 0.00% | +2,686+43.0% | Added |
| Cambria Investment Management, L.P. | 9,000 | $435.2K | 0.03% | −1,575−14.9% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,092 | $439.7K | 0.00% | −610−6.3% | Reduced |
| Cerity Partners LLC | 9,245 | $447.1K | 0.00% | −3,811−29.2% | Reduced |
| Royal Bank of Canada | 9,964 | $482.0K | 0.00% | +2,334+30.6% | Added |
| Cache Advisors, LLC | 10,143 | $490.5K | 0.19% | 00.0% | Unchanged |
| Magnetar Financial LLC | 11,154 | $539.4K | 0.01% | +11,154 | New |
| Franklin Street Advisors Inc | 11,300 | $546.0K | 0.04% | 00.0% | Unchanged |
| Profund Advisors LLC | 11,559 | $559.0K | 0.02% | −9,090−44.0% | Reduced |
| Gsa Capital Partners LLP | 11,963 | $579.0K | 0.05% | +11,963 | New |
| Teacher Retirement System of Texas | 12,025 | $581.5K | 0.00% | −1,074−8.2% | Reduced |
| Royce & Associates LP | 12,255 | $592.7K | 0.01% | +12,255 | New |
| Arizona State Retirement System | 12,801 | $619.1K | 0.00% | −40.0% | Reduced |