Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 241
- +4 vs. Q3 2024
- Shares held
- 63.3M
- +1.83M (+3.0%) vs. Q3 2024
- Total value
- $2.44B
- −$321.9M (−11.6%) vs. Q3 2024
- New holders
- 45
- 91 more added
- Sold out
- 41
- 76 more reduced
3 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State of Alaska, Department of Revenue | 33,871 | $1.31M | 0.01% | +256+0.8% | Added |
| Illinois Municipal Retirement Fund | 33,509 | $1.29M | 0.02% | +4,385+15.1% | Added |
| Massachusetts Financial Services Co | 32,449 | $1.25M | 0.00% | +32,449 | New |
| Hennion & Walsh Asset Management, Inc. | 32,074 | $1.24M | 0.06% | −5,339−14.3% | Reduced |
| Intech Investment Management LLC | 31,480 | $1.22M | 0.01% | +12,352+64.6% | Added |
| Los Angeles Capital Management LLC | 31,366 | $1.21M | 0.00% | +8,920+39.7% | Added |
| Cavalier Investments, LLC | 31,252 | $1.21M | 0.40% | +1,296+4.3% | Added |
| Corebridge Financial, Inc. | 31,155 | $1.20M | 0.01% | −2,407−7.2% | Reduced |
| ExodusPoint Capital Management, LP | 29,870 | $1.15M | 0.01% | +29,870 | New |
| Louisiana State Employees Retirement System | 28,800 | $1.11M | 0.02% | +300+1.1% | Added |
| Capital Fund Management S.A. | 28,058 | $1.08M | 0.01% | +28,058 | New |
| State of Tennessee, Treasury Department | 27,076 | $1.05M | 0.00% | −667−2.4% | Reduced |
| Ensign Peak Advisors, Inc | 27,036 | $1.04M | 0.00% | 00.0% | Unchanged |
| Winton Group Ltd | 26,768 | $1.03M | 0.07% | +785+3.0% | Added |
| New York State Teachers Retirement System | 24,592 | $949.0K | 0.00% | 00.0% | Unchanged |
| SEI Investments Co | 24,568 | $948.3K | 0.00% | −10,510−30.0% | Reduced |
| Bellevue Group AG | 23,718 | $915.5K | 0.02% | +11,372+92.1% | Added |
| Summit Global Investments | 23,557 | $909.0K | 0.06% | +23,557 | New |
| STRS Ohio | 23,500 | $907.1K | 0.00% | +2,000+9.3% | Added |
| Yousif Capital Management, LLC | 22,918 | $884.6K | 0.01% | −322−1.4% | Reduced |
| Sierra Summit Advisors LLC | 22,282 | $860.1K | 0.17% | +1,115+5.3% | Added |
| Janus Henderson Group PLC | 21,454 | $827.8K | 0.00% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 21,349 | $824.1K | 0.00% | +13,575+174.6% | Added |
| Toroso Investments, LLC | 21,012 | $811.1K | 0.01% | −1,050−4.8% | Reduced |
| Profund Advisors LLC | 20,649 | $797.1K | 0.03% | +566+2.8% | Added |
| Comerica Bank | 20,558 | $793.5K | 0.00% | −346−1.7% | Reduced |
| ProShare Advisors LLC | 20,457 | $789.6K | 0.00% | +4,776+30.5% | Added |
| Teachers Retirement System of the State of Kentucky | 20,200 | $780.0K | 0.01% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 20,188 | $779.3K | 0.02% | +20,188 | New |
| Maryland State Retirement & Pension System | 20,170 | $778.6K | 0.02% | +278+1.4% | Added |
| Braidwell LP | 20,109 | $776.2K | 0.02% | +20,109 | New |
| Marshall Wace, LLP | 19,716 | $761.0K | 0.00% | −295,657−93.7% | Reduced |
| BNP Paribas Arbitrage, SA | 19,465 | $751.3K | 0.00% | −829−4.1% | Reduced |
| Guggenheim Capital LLC | 19,078 | $736.4K | 0.01% | +11,180+141.6% | Added |
| Mariner, LLC | 17,983 | $694.1K | 0.00% | +2,004+12.5% | Added |
| New York State Common Retirement Fund | 17,882 | $690.2K | 0.00% | −2,300−11.4% | Reduced |
| Algert Global LLC | 17,720 | $684.0K | 0.02% | −97,959−84.7% | Reduced |
| Handelsbanken Fonder AB | 17,600 | $679.0K | 0.00% | +17,600 | New |
| Amalgamated Bank | 17,405 | $672.0K | 0.01% | +81+0.5% | Added |
| State Board of Administration of Florida Retirement System | 16,303 | $629.3K | 0.00% | 00.0% | Unchanged |
| Moran Wealth Management, LLC | 15,961 | $616.1K | 0.02% | +931+6.2% | Added |
| DekaBank Deutsche Girozentrale | 15,800 | $610.0K | 0.00% | 00.0% | Unchanged |
| Aviva PLC | 14,627 | $564.6K | 0.00% | +14,627 | New |
| Oregon Public Employees Retirement Fund | 14,000 | $540.4K | 0.01% | +100+0.7% | Added |
| Erste Asset Management GmbH | 13,500 | $526.0K | 0.01% | +13,500 | New |
| Cerity Partners LLC | 13,056 | $518.3K | 0.00% | −1,185−8.3% | Reduced |
| Teacher Retirement System of Texas | 13,099 | $506.0K | 0.00% | +2,067+18.7% | Added |
| Arizona State Retirement System | 12,805 | $494.3K | 0.00% | +139+1.1% | Added |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 12,723 | $491.1K | 0.00% | +132+1.0% | Added |
| Crestline Management, LP | 12,681 | $489.5K | 0.02% | +12,681 | New |
| China Universal Asset Management Co., Ltd. | 12,637 | $487.8K | 0.05% | +1,308+11.5% | Added |
| Police & Firemen's Retirement System of New Jersey | 12,441 | $480.2K | 0.00% | +12,441 | New |
| Scientech Research LLC | 12,054 | $465.3K | 0.13% | −2,473−17.0% | Reduced |
| Franklin Street Advisors Inc | 11,300 | $436.0K | 0.03% | −100−0.9% | Reduced |
| Allianz Asset Management GmbH | 11,000 | $424.6K | 0.00% | −8,300−43.0% | Reduced |
| Cambria Investment Management, L.P. | 10,575 | $408.2K | 0.02% | +10,575 | New |
| CWM Advisors, LLC | 10,555 | $407.4K | 0.05% | −25,959−71.1% | Reduced |
| Cache Advisors, LLC | 10,143 | $391.5K | 0.16% | +10,143 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,702 | $374.5K | 0.00% | −126−1.3% | Reduced |
| Mutual of America Capital Management LLC | 9,027 | $348.4K | 0.00% | +167+1.9% | Added |
| PEAK6 LLC | 9,000 | $347.4K | 0.01% | +9,000 | New |
| Envestnet Asset Management Inc | 8,981 | $346.7K | 0.00% | −3,802−29.7% | Reduced |
| Glenmede Trust Co NA | 8,953 | $345.6K | 0.00% | −6,028−40.2% | Reduced |
| KLP Kapitalforvaltning AS | 8,700 | $335.8K | 0.00% | +8,700 | New |
| HSBC Holdings PLC | 8,128 | $312.7K | 0.00% | +2,259+38.5% | Added |
| HRT Financial LP | 8,025 | $309.0K | 0.00% | +8,025 | New |
| State of Wyoming | 7,832 | $302.3K | 0.04% | +832+11.9% | Added |
| Royal Bank of Canada | 7,630 | $295.0K | 0.00% | −5,933−43.7% | Reduced |
| Tower Research Capital LLC (TRC) | 7,369 | $284.4K | 0.01% | +7,009+1,946.9% | Added |
| AlphaCentric Advisors LLC | 7,123 | $274.9K | 0.27% | −17,877−71.5% | Reduced |
| XTX Topco Ltd | 6,744 | $260.3K | 0.02% | −8,057−54.4% | Reduced |
| Freestone Grove Partners LP | 6,644 | $256.5K | 0.00% | +6,644 | New |
| Contravisory Investment Management, Inc. | 6,498 | $250.8K | 0.05% | +6,498 | New |
| Creative Planning | 6,448 | $248.9K | 0.00% | −1,056−14.1% | Reduced |
| Bleakley Financial Group, LLC | 6,367 | $245.8K | 0.01% | −664−9.4% | Reduced |
| Bank of Montreal | 6,250 | $241.3K | 0.00% | +270+4.5% | Added |
| King Wealth | 6,000 | $232.0K | 0.03% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 5,975 | $230.6K | 0.00% | −97,867−94.2% | Reduced |
| Ameritas Investment Partners, Inc. | 5,912 | $228.2K | 0.01% | 00.0% | Unchanged |
| Captrust Financial Advisors | 5,878 | $226.9K | 0.00% | −248−4.0% | Reduced |
| Acadian Asset Management LLC | 5,889 | $226.0K | 0.00% | +3,502+146.7% | Added |
| CAPROCK Group, Inc. | 5,802 | $224.0K | 0.01% | +5,802 | New |
| Advantage Alpha Capital Partners LP | 5,742 | $221.6K | 0.05% | −5,594−49.3% | Reduced |
| D. E. Shaw & Co., Inc. | 5,704 | $220.2K | 0.00% | −21,121−78.7% | Reduced |
| Two Sigma Investments, LP | 5,658 | $218.4K | 0.00% | −53−0.9% | Reduced |
| Kestra Advisory Services, LLC | 5,647 | $218.0K | 0.00% | +464+9.0% | Added |
| Two Sigma Securities, LLC | 5,505 | $212.5K | 0.04% | +5,505 | New |
| CIBC World Markets Corp | 5,468 | $211.1K | 0.00% | +5,468 | New |
| Simplex Trading, LLC | 5,487 | $211.0K | 0.01% | +5,487 | New |
| Cornerstone Investment Partners, LLC | 5,416 | $209.1K | 0.01% | −5−0.1% | Reduced |
| Nisa Investment Advisors, LLC | 3,133 | $120.9K | 0.00% | +295+10.4% | Added |
| New Vernon Capital Holdings II LLC | 3,061 | $118.2K | 0.08% | +3,061 | New |
| Advisors Asset Management, Inc. | 2,598 | $100.3K | 0.00% | +2,598 | New |
| Quest Partners LLC | 2,177 | $84.0K | 0.01% | −21,770−90.9% | Reduced |
| US Bancorp | 2,130 | $82.2K | 0.00% | −5,736−72.9% | Reduced |
| KBC Group NV | 2,093 | $81.0K | 0.00% | +737+54.4% | Added |
| Mirae Asset Global Investments Co., Ltd. | 1,986 | $77.4K | 0.00% | −144−6.8% | Reduced |
| Amundi | 2,033 | $76.5K | 0.00% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 1,761 | $68.0K | 0.03% | −919−34.3% | Reduced |
| Covestor Ltd | 1,643 | $63.0K | 0.04% | +1,612+5,200.0% | Added |