Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 241
- +4 vs. Q3 2024
- Shares held
- 63.3M
- +1.83M (+3.0%) vs. Q3 2024
- Total value
- $2.44B
- −$321.9M (−11.6%) vs. Q3 2024
- New holders
- 45
- 91 more added
- Sold out
- 41
- 76 more reduced
3 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Abound Wealth Management | 4 | $155 | 0.00% | −1−20.0% | Reduced |
| Parkside Financial Bank & Trust | 4 | $155 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 5 | $193 | 0.00% | +5 | New |
| IFP Advisors, Inc | 5 | $193 | 0.00% | +5 | New |
| Federated Hermes, Inc. | 7 | $270 | 0.00% | +7 | New |
| EverSource Wealth Advisors, LLC | 10 | $386 | 0.00% | +10 | New |
| Principal Securities, Inc. | 12 | $463 | 0.00% | −3−20.0% | Reduced |
| Larson Financial Group LLC | 15 | $579 | 0.00% | −2−11.8% | Reduced |
| Bell Investment Advisors, Inc | 17 | $657 | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 18 | $695 | 0.00% | +18 | New |
| SRS Capital Advisors, Inc. | 21 | $811 | 0.00% | +21 | New |
| Picton Mahoney Asset Management | 25 | $1.00K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 27 | $1.04K | 0.00% | −16−37.2% | Reduced |
| Russell Investments Group, Ltd. | 29 | $1.12K | 0.00% | +5+20.8% | Added |
| Wolff Wiese Magana LLC | 35 | $1.35K | 0.00% | 00.0% | Unchanged |
| Farmers & Merchants Investments Inc | 35 | $1.35K | 0.00% | +35 | New |
| Farther Finance Advisors, LLC | 44 | $1.70K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 45 | $1.74K | 0.00% | −5−10.0% | Reduced |
| Massmutual Trust Co FSB | 51 | $1.97K | 0.00% | +48+1,600.0% | Added |
| Sterling Capital Management LLC | 60 | $2.32K | 0.00% | 00.0% | Unchanged |
| Lindbrook Capital, LLC | 66 | $2.55K | 0.00% | −10−13.2% | Reduced |
| Group One Trading, L.P. | 70 | $2.70K | 0.00% | +70 | New |
| CoreCap Advisors, LLC | 76 | $2.93K | 0.00% | −248−76.5% | Reduced |
| Harvest Fund Management Co., Ltd | 80 | $3.00K | 0.00% | −1,464−94.8% | Reduced |
| Fifth Third Bancorp | 92 | $3.55K | 0.00% | −11−10.7% | Reduced |
| Danske Bank A/S | 100 | $3.86K | 0.00% | −300−75.0% | Reduced |
| Clearstead Advisors, LLC | 110 | $4.25K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 131 | $5.06K | 0.00% | 00.0% | Unchanged |
| Umb Bank N A | 163 | $6.29K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 215 | $8.00K | 0.00% | 00.0% | Unchanged |
| Bessemer Group Inc | 201 | $8.00K | 0.00% | +107+113.8% | Added |
| Assetmark, Inc | 245 | $9.46K | 0.00% | +80+48.5% | Added |
| Global Retirement Partners, LLC | 304 | $11.7K | 0.00% | −44−12.6% | Reduced |
| CWM, LLC | 386 | $15.0K | 0.00% | −887−69.7% | Reduced |
| GAMMA Investing LLC | 475 | $18.3K | 0.00% | −77−13.9% | Reduced |
| Smartleaf Asset Management LLC | 501 | $19.3K | 0.00% | +411+456.7% | Added |
| Advisor Group Holdings, Inc. | 592 | $22.9K | 0.00% | +414+232.6% | Added |
| FNY Investment Advisers, LLC | 1,000 | $38.0K | 0.02% | +1,000 | New |
| Exchange Traded Concepts, LLC | 1,025 | $39.6K | 0.00% | +64+6.7% | Added |
| GF Fund Management Co. Ltd. | 1,251 | $48.3K | 0.00% | +1,251 | New |
| The PNC Financial Services Group, Inc. | 1,441 | $55.6K | 0.00% | −288−16.7% | Reduced |
| Covestor Ltd | 1,643 | $63.0K | 0.04% | +1,612+5,200.0% | Added |
| Virtus ETF Advisers LLC | 1,761 | $68.0K | 0.03% | −919−34.3% | Reduced |
| Amundi | 2,033 | $76.5K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 1,986 | $77.4K | 0.00% | −144−6.8% | Reduced |
| KBC Group NV | 2,093 | $81.0K | 0.00% | +737+54.4% | Added |
| US Bancorp | 2,130 | $82.2K | 0.00% | −5,736−72.9% | Reduced |
| Quest Partners LLC | 2,177 | $84.0K | 0.01% | −21,770−90.9% | Reduced |
| Advisors Asset Management, Inc. | 2,598 | $100.3K | 0.00% | +2,598 | New |
| New Vernon Capital Holdings II LLC | 3,061 | $118.2K | 0.08% | +3,061 | New |
| Nisa Investment Advisors, LLC | 3,133 | $120.9K | 0.00% | +295+10.4% | Added |
| Cornerstone Investment Partners, LLC | 5,416 | $209.1K | 0.01% | −5−0.1% | Reduced |
| Simplex Trading, LLC | 5,487 | $211.0K | 0.01% | +5,487 | New |
| CIBC World Markets Corp | 5,468 | $211.1K | 0.00% | +5,468 | New |
| Two Sigma Securities, LLC | 5,505 | $212.5K | 0.04% | +5,505 | New |
| Kestra Advisory Services, LLC | 5,647 | $218.0K | 0.00% | +464+9.0% | Added |
| Two Sigma Investments, LP | 5,658 | $218.4K | 0.00% | −53−0.9% | Reduced |
| D. E. Shaw & Co., Inc. | 5,704 | $220.2K | 0.00% | −21,121−78.7% | Reduced |
| Advantage Alpha Capital Partners LP | 5,742 | $221.6K | 0.05% | −5,594−49.3% | Reduced |
| CAPROCK Group, Inc. | 5,802 | $224.0K | 0.01% | +5,802 | New |
| Acadian Asset Management LLC | 5,889 | $226.0K | 0.00% | +3,502+146.7% | Added |
| Captrust Financial Advisors | 5,878 | $226.9K | 0.00% | −248−4.0% | Reduced |
| Ameritas Investment Partners, Inc. | 5,912 | $228.2K | 0.01% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 5,975 | $230.6K | 0.00% | −97,867−94.2% | Reduced |
| King Wealth | 6,000 | $232.0K | 0.03% | 00.0% | Unchanged |
| Bank of Montreal | 6,250 | $241.3K | 0.00% | +270+4.5% | Added |
| Bleakley Financial Group, LLC | 6,367 | $245.8K | 0.01% | −664−9.4% | Reduced |
| Creative Planning | 6,448 | $248.9K | 0.00% | −1,056−14.1% | Reduced |
| Contravisory Investment Management, Inc. | 6,498 | $250.8K | 0.05% | +6,498 | New |
| Freestone Grove Partners LP | 6,644 | $256.5K | 0.00% | +6,644 | New |
| XTX Topco Ltd | 6,744 | $260.3K | 0.02% | −8,057−54.4% | Reduced |
| AlphaCentric Advisors LLC | 7,123 | $274.9K | 0.27% | −17,877−71.5% | Reduced |
| Tower Research Capital LLC (TRC) | 7,369 | $284.4K | 0.01% | +7,009+1,946.9% | Added |
| Royal Bank of Canada | 7,630 | $295.0K | 0.00% | −5,933−43.7% | Reduced |
| State of Wyoming | 7,832 | $302.3K | 0.04% | +832+11.9% | Added |
| HRT Financial LP | 8,025 | $309.0K | 0.00% | +8,025 | New |
| HSBC Holdings PLC | 8,128 | $312.7K | 0.00% | +2,259+38.5% | Added |
| KLP Kapitalforvaltning AS | 8,700 | $335.8K | 0.00% | +8,700 | New |
| Glenmede Trust Co NA | 8,953 | $345.6K | 0.00% | −6,028−40.2% | Reduced |
| Envestnet Asset Management Inc | 8,981 | $346.7K | 0.00% | −3,802−29.7% | Reduced |
| PEAK6 LLC | 9,000 | $347.4K | 0.01% | +9,000 | New |
| Mutual of America Capital Management LLC | 9,027 | $348.4K | 0.00% | +167+1.9% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,702 | $374.5K | 0.00% | −126−1.3% | Reduced |
| Cache Advisors, LLC | 10,143 | $391.5K | 0.16% | +10,143 | New |
| CWM Advisors, LLC | 10,555 | $407.4K | 0.05% | −25,959−71.1% | Reduced |
| Cambria Investment Management, L.P. | 10,575 | $408.2K | 0.02% | +10,575 | New |
| Allianz Asset Management GmbH | 11,000 | $424.6K | 0.00% | −8,300−43.0% | Reduced |
| Franklin Street Advisors Inc | 11,300 | $436.0K | 0.03% | −100−0.9% | Reduced |
| Scientech Research LLC | 12,054 | $465.3K | 0.13% | −2,473−17.0% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 12,441 | $480.2K | 0.00% | +12,441 | New |
| China Universal Asset Management Co., Ltd. | 12,637 | $487.8K | 0.05% | +1,308+11.5% | Added |
| Crestline Management, LP | 12,681 | $489.5K | 0.02% | +12,681 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 12,723 | $491.1K | 0.00% | +132+1.0% | Added |
| Arizona State Retirement System | 12,805 | $494.3K | 0.00% | +139+1.1% | Added |
| Teacher Retirement System of Texas | 13,099 | $506.0K | 0.00% | +2,067+18.7% | Added |
| Cerity Partners LLC | 13,056 | $518.3K | 0.00% | −1,185−8.3% | Reduced |
| Erste Asset Management GmbH | 13,500 | $526.0K | 0.01% | +13,500 | New |
| Oregon Public Employees Retirement Fund | 14,000 | $540.4K | 0.01% | +100+0.7% | Added |
| Aviva PLC | 14,627 | $564.6K | 0.00% | +14,627 | New |
| DekaBank Deutsche Girozentrale | 15,800 | $610.0K | 0.00% | 00.0% | Unchanged |