Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2023
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 138
- +2 vs. Q4 2022
- Shares held
- 53.2M
- +4.49M (+9.2%) vs. Q4 2022
- Total value
- $1.22B
- +$693.0M (+130.4%) vs. Q4 2022
- New holders
- 34
- 44 more added
- Sold out
- 32
- 44 more reduced
1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ghost Tree Capital, LLC | 225,000 | $5.17M | 1.96% | +225,000 | New |
| BNP Paribas Arbitrage, SA | 237,624 | $5.47M | 0.01% | +146,599+161.1% | Added |
| Invesco Ltd. | 277,936 | $6.39M | 0.00% | +246,384+780.9% | Added |
| OrbiMed Advisors LLC | 301,000 | $6.92M | 0.14% | +301,000 | New |
| Two Sigma Investments, LP | 307,700 | $7.08M | 0.02% | −184,265−37.5% | Reduced |
| Kennedy Capital Management, Inc. | 331,282 | $7.62M | 0.22% | −18,851−5.4% | Reduced |
| Charles Schwab Investment Management Inc | 361,158 | $8.31M | 0.00% | +21,137+6.2% | Added |
| Price T Rowe Associates Inc | 415,274 | $9.55M | 0.00% | +415,274 | New |
| Northern Trust Corp | 422,636 | $9.72M | 0.00% | +4,029+1.0% | Added |
| Jennison Associates LLC | 428,938 | $9.87M | 0.01% | +428,938 | New |
| Two Sigma Advisers, LP | 449,800 | $10.3M | 0.03% | −153,700−25.5% | Reduced |
| Goldman Sachs Group Inc | 459,450 | $10.6M | 0.00% | −157,274−25.5% | Reduced |
| Voloridge Investment Management, LLC | 465,323 | $10.7M | 0.05% | +297,954+178.0% | Added |
| Candriam Luxembourg S.C.A. | 625,000 | $13.2M | 0.09% | +625,000 | New |
| Barclays PLC | 583,737 | $13.4M | 0.01% | +328,850+129.0% | Added |
| Woodline Partners LP | 618,615 | $14.2M | 0.20% | +106,475+20.8% | Added |
| Renaissance Technologies LLC | 690,867 | $15.9M | 0.02% | +432,000+166.9% | Added |
| Bank of America Corp | 766,990 | $17.6M | 0.00% | +422,043+122.4% | Added |
| 683 Capital Management, LLC | 791,000 | $18.2M | 1.63% | +583,200+280.7% | Added |
| Nuveen Asset Management, LLC | 828,471 | $19.1M | 0.01% | +467,757+129.7% | Added |
| Geode Capital Management, LLC | 925,993 | $21.3M | 0.00% | +46,102+5.2% | Added |
| Deutsche Bank AG | 958,891 | $22.1M | 0.01% | +33,229+3.6% | Added |
| Perceptive Advisors LLC | 965,152 | $22.2M | 0.66% | +965,152 | New |
| Millennium Management LLC | 1,122,342 | $25.8M | 0.03% | −223,047−16.6% | Reduced |
| Citadel Advisors LLC | 1,164,680 | $26.8M | 0.03% | −1,190,634−50.6% | Reduced |
| Dimensional Fund Advisors LP | 1,262,259 | $29.0M | 0.01% | +185,033+17.2% | Added |
| Marshall Wace, LLP | 1,366,080 | $31.4M | 0.08% | −88,366−6.1% | Reduced |
| Kynam Capital Management, LP | 1,375,000 | $31.6M | 4.09% | +854,078+164.0% | Added |
| Morgan Stanley | 1,570,510 | $36.1M | 0.00% | −868,007−35.6% | Reduced |
| Cormorant Asset Management, LP | 1,700,000 | $39.1M | 2.58% | +1,700,000 | New |
| State Street Corp | 2,413,701 | $55.5M | 0.00% | −1,379,225−36.4% | Reduced |
| Johnson & Johnson | 2,449,183 | $56.3M | 18.32% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 2,558,000 | $58.8M | 0.13% | +1,790,955+233.5% | Added |
| Farallon Capital Management, L.L.C. | 2,615,014 | $60.1M | 0.36% | −1,036,873−28.4% | Reduced |
| Vanguard Group Inc | 3,241,293 | $74.5M | 0.00% | +143,579+4.6% | Added |
| BVF Inc | 3,775,900 | $86.8M | 3.17% | +3,775,900 | New |
| BlackRock Inc. | 4,402,217 | $101.3M | 0.00% | +750,060+20.5% | Added |
| RTW Investments, LP | 4,600,799 | $105.8M | 2.20% | +1,008,813+28.1% | Added |
| Bain Capital Life Sciences Investors, LLC | 0 | $0 | 0.00% | −2,364,410−100.0% | Sold out |
| Braidwell LP | 0 | $0 | 0.00% | −927,800−100.0% | Sold out |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −871,493−100.0% | Sold out |
| Sio Capital Management, LLC | 0 | $0 | 0.00% | −434,635−100.0% | Sold out |
| Madison Avenue Partners, LP | 0 | $0 | 0.00% | −406,593−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −316,500−100.0% | Sold out |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −236,000−100.0% | Sold out |
| Norges Bank | 0 | $0 | 0.00% | −148,700−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −135,706−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −125,119−100.0% | Sold out |
| Tekla Capital Management LLC | 0 | $0 | 0.00% | −122,271−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −94,070−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −90,107−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −81,835−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −55,839−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −40,970−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −28,970−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −23,000−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −22,300−100.0% | Sold out |
| Caxton Associates LP | 0 | $0 | 0.00% | −21,853−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −21,770−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −14,318−100.0% | Sold out |
| DuPont Capital Management Corp | 0 | $0 | 0.00% | −13,127−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −12,942−100.0% | Sold out |
| Alpine Global Management, LLC | 0 | $0 | 0.00% | −10,279−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −10,198−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −9,199−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −6,700−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −6,404−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −1,307−100.0% | Sold out |
| Sofos Investments, Inc. | 0 | $0 | 0.00% | −11−100.0% | Sold out |
| Rothschild & Co Asset Management US Inc. | – | – | – | – | Not filed |