Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 140
- −9 vs. Q4 2021
- Shares held
- 50.6M
- +1.19M (+2.4%) vs. Q4 2021
- Total value
- $1.19B
- −$490.3M (−29.1%) vs. Q4 2021
- New holders
- 20
- 54 more added
- Sold out
- 29
- 47 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Citadel Advisors LLC | 186,824 | $4.42M | 0.01% | +151,276+425.6% | Added |
| Rafferty Asset Management, LLC | 208,094 | $4.93M | 0.03% | +42,322+25.5% | Added |
| Two Sigma Advisers, LP | 214,700 | $5.08M | 0.01% | +175,900+453.4% | Added |
| Bank of America Corp | 247,876 | $5.87M | 0.00% | +128,269+107.2% | Added |
| Opaleye Management Inc. | 251,500 | $5.96M | 1.85% | −90,500−26.5% | Reduced |
| Sessa Capital IM, L.P. | 257,000 | $6.09M | 0.37% | +257,000 | New |
| Lord, Abbett & Co. LLC | 275,787 | $6.53M | 0.02% | +112,123+68.5% | Added |
| Two Sigma Investments, LP | 288,518 | $6.83M | 0.02% | +260,418+926.8% | Added |
| Affinity Asset Advisors, LLC | 300,000 | $7.10M | 2.82% | +58,881+24.4% | Added |
| Price T Rowe Associates Inc | 300,468 | $7.12M | 0.00% | −76,664−20.3% | Reduced |
| Polar Capital Holdings Plc | 303,429 | $7.18M | 0.04% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 325,259 | $7.70M | 0.00% | +8,080+2.5% | Added |
| Commodore Capital LP | 331,886 | $7.86M | 1.76% | −473,687−58.8% | Reduced |
| Goldman Sachs Group Inc | 346,359 | $8.20M | 0.00% | +222,730+180.2% | Added |
| Rothschild & Co Asset Management US Inc. | 379,126 | $8.98M | 0.11% | −111,898−22.8% | Reduced |
| EcoR1 Capital, LLC | 381,711 | $9.04M | 0.28% | −2,257,995−85.5% | Reduced |
| Altium Capital Management LP | 386,000 | $9.14M | 3.19% | +40,000+11.6% | Added |
| Northern Trust Corp | 435,078 | $10.3M | 0.00% | −20,333−4.5% | Reduced |
| Millennium Management LLC | 460,115 | $10.9M | 0.01% | +69,042+17.7% | Added |
| Sofinnova Investments, Inc. | 547,441 | $13.0M | 1.09% | +65,184+13.5% | Added |
| Fairmount Funds Management LLC | 549,988 | $13.0M | 3.08% | +549,988 | New |
| Woodline Partners LP | 588,694 | $13.9M | 0.23% | +95,707+19.4% | Added |
| Adage Capital Partners GP, L.L.C. | 600,045 | $14.2M | 0.03% | +150,000+33.3% | Added |
| Cowen and Company, LLC | 722,575 | $17.1M | 1.73% | +719,397+22,636.8% | Added |
| Tri Locum Partners LP | 769,250 | $18.2M | 7.12% | +455,321+145.0% | Added |
| Artal Group S.A. | 800,100 | $18.9M | 0.80% | −449,900−36.0% | Reduced |
| Obermeyer Wood Investment Counsel, LLLP | 801,625 | $19.0M | 1.14% | +12,683+1.6% | Added |
| Deutsche Bank AG | 822,323 | $19.5M | 0.01% | −2,549−0.3% | Reduced |
| Geode Capital Management, LLC | 832,921 | $19.7M | 0.00% | +54,840+7.0% | Added |
| Dimensional Fund Advisors LP | 862,892 | $20.4M | 0.01% | −11,759−1.3% | Reduced |
| Farallon Capital Management, L.L.C. | 1,134,457 | $26.9M | 0.15% | −782,677−40.8% | Reduced |
| Morgan Stanley | 1,337,103 | $31.7M | 0.00% | +1,229,687+1,144.8% | Added |
| Vanguard Group Inc | 2,330,074 | $55.2M | 0.00% | −18,092−0.8% | Reduced |
| Johnson & Johnson | 2,449,183 | $58.0M | 10.96% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 2,915,100 | $69.0M | 0.31% | +495,337+20.5% | Added |
| BlackRock Inc. | 3,246,174 | $76.9M | 0.00% | −35,462−1.1% | Reduced |
| State Street Corp | 3,256,808 | $77.1M | 0.00% | +685,238+26.6% | Added |
| BVF Inc | 4,183,219 | $99.1M | 3.96% | +531,460+14.6% | Added |
| RTW Investments, LP | 4,794,499 | $113.5M | 2.35% | +2,194,677+84.4% | Added |
| FMR LLC | 7,128,579 | $168.8M | 0.01% | +281,302+4.1% | Added |
| Deerfield Management Company, L.P. (Series C) | 0 | $0 | 0.00% | −1,172,943−100.0% | Sold out |
| Samlyn Capital, LLC | 0 | $0 | 0.00% | −448,908−100.0% | Sold out |
| Mangrove Partners | 0 | $0 | 0.00% | −433,137−100.0% | Sold out |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −421,660−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −250,000−100.0% | Sold out |
| Alberta Investment Management Corp | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −76,396−100.0% | Sold out |
| Resolute Capital Asset Partners LLC | 0 | $0 | 0.00% | −55,000−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −43,286−100.0% | Sold out |
| Bamco Inc | 0 | $0 | 0.00% | −26,000−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −21,400−100.0% | Sold out |
| HAP Trading, LLC | 0 | $0 | 0.00% | −19,166−100.0% | Sold out |
| Gyon Technologies Capital Management, LP | 0 | $0 | 0.00% | −18,882−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −18,524−100.0% | Sold out |
| Putnam Investments LLC | 0 | $0 | 0.00% | −15,484−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −15,177−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −13,104−100.0% | Sold out |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −11,948−100.0% | Sold out |
| Victory Capital Management Inc | 0 | $0 | 0.00% | −9,612−100.0% | Sold out |
| Janus Henderson Group PLC | 0 | $0 | 0.00% | −8,014−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −7,833−100.0% | Sold out |
| Principal Financial Group Inc | 0 | $0 | 0.00% | −7,607−100.0% | Sold out |
| Coastal Bridge Advisors, LLC | 0 | $0 | 0.00% | −7,400−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −7,225−100.0% | Sold out |
| Central Trust Co | 0 | $0 | 0.00% | −1,625−100.0% | Sold out |
| Captrust Financial Advisors | 0 | $0 | 0.00% | −1,153−100.0% | Sold out |
| Truvestments Capital LLC | 0 | $0 | 0.00% | −250−100.0% | Sold out |
| TCI Wealth Advisors, Inc. | 0 | $0 | 0.00% | −219−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −16−100.0% | Sold out |