Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2021
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 149
- +17 vs. Q3 2021
- Shares held
- 49.4M
- +3.04M (+6.6%) vs. Q3 2021
- Total value
- $1.68B
- +$863.7M (+105.2%) vs. Q3 2021
- New holders
- 36
- 58 more added
- Sold out
- 19
- 36 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Barclays PLC | 120,597 | $4.12M | 0.00% | +83,600+226.0% | Added |
| Goldman Sachs Group Inc | 123,629 | $4.23M | 0.00% | −299,566−70.8% | Reduced |
| J. Goldman & Co LP | 130,517 | $4.46M | 0.41% | +130,517 | New |
| SEI Investments Co | 132,313 | $4.53M | 0.01% | +86,138+186.5% | Added |
| Allianz Asset Management GmbH | 134,793 | $4.61M | 0.00% | +85,622+174.1% | Added |
| Citigroup Inc | 137,751 | $4.71M | 0.00% | +86,566+169.1% | Added |
| Bank of New York Mellon Corp | 138,494 | $4.74M | 0.00% | +7,361+5.6% | Added |
| Twin Lakes Capital Management, LLC | 138,580 | $4.74M | 2.53% | −707−0.5% | Reduced |
| Russell Investments Group, Ltd. | 163,589 | $5.59M | 0.01% | +86,587+112.4% | Added |
| Lord, Abbett & Co. LLC | 163,664 | $5.60M | 0.01% | +163,664 | New |
| Rafferty Asset Management, LLC | 165,772 | $5.67M | 0.03% | +96,642+139.8% | Added |
| Voloridge Investment Management, LLC | 183,648 | $6.28M | 0.03% | −366,435−66.6% | Reduced |
| Caption Management, LLC | 192,702 | $6.59M | 0.41% | +82,702+75.2% | Added |
| Affinity Asset Advisors, LLC | 241,119 | $8.25M | 3.52% | +241,119 | New |
| Logos Global Management LP | 250,000 | $8.55M | 0.88% | +250,000 | New |
| Susquehanna International Group, LLP | 296,413 | $10.1M | 0.02% | +29,030+10.9% | Added |
| Polar Capital Holdings Plc | 303,429 | $10.4M | 0.05% | +84,493+38.6% | Added |
| Tri Locum Partners LP | 313,929 | $10.7M | 4.30% | +313,929 | New |
| Charles Schwab Investment Management Inc | 317,179 | $10.8M | 0.00% | +7,347+2.4% | Added |
| Opaleye Management Inc. | 342,000 | $11.7M | 2.48% | +11,778+3.6% | Added |
| Altium Capital Management LP | 346,000 | $11.8M | 3.32% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 377,132 | $12.9M | 0.00% | −114,509−23.3% | Reduced |
| Millennium Management LLC | 391,073 | $13.4M | 0.01% | −131,798−25.2% | Reduced |
| Deep Track Capital, LP | 421,660 | $14.4M | 1.07% | +421,660 | New |
| Mangrove Partners | 433,137 | $14.8M | 1.10% | +433,137 | New |
| JPMorgan Chase & Co | 436,453 | $14.9M | 0.00% | +7,758+1.8% | Added |
| Samlyn Capital, LLC | 448,908 | $15.4M | 0.24% | +448,908 | New |
| Adage Capital Partners GP, L.L.C. | 450,045 | $15.4M | 0.03% | +150,000+50.0% | Added |
| Northern Trust Corp | 455,411 | $15.6M | 0.00% | −1,566−0.3% | Reduced |
| Sofinnova Investments, Inc. | 482,257 | $16.5M | 1.06% | +184,548+62.0% | Added |
| Rothschild & Co Asset Management US Inc. | 491,024 | $16.8M | 0.20% | +273,541+125.8% | Added |
| Woodline Partners LP | 492,987 | $16.9M | 0.25% | +492,987 | New |
| Geode Capital Management, LLC | 778,081 | $26.6M | 0.00% | +49,151+6.7% | Added |
| Obermeyer Wood Investment Counsel, LLLP | 788,942 | $27.0M | 1.45% | +12,253+1.6% | Added |
| Commodore Capital LP | 805,573 | $27.6M | 6.38% | +307,494+61.7% | Added |
| Deutsche Bank AG | 824,872 | $28.2M | 0.01% | +1,582+0.2% | Added |
| Dimensional Fund Advisors LP | 874,651 | $29.9M | 0.01% | −1,081−0.1% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 1,172,943 | $40.1M | 0.84% | −221,057−15.9% | Reduced |
| Artal Group S.A. | 1,250,000 | $42.8M | 1.26% | −250,000−16.7% | Reduced |
| Farallon Capital Management, L.L.C. | 1,917,134 | $65.6M | 0.37% | −474,866−19.9% | Reduced |
| Vanguard Group Inc | 2,348,166 | $80.3M | 0.00% | −5,620−0.2% | Reduced |
| Point72 Asset Management, L.P. | 2,419,763 | $82.8M | 0.37% | −1,967,537−44.8% | Reduced |
| Johnson & Johnson | 2,449,183 | $83.8M | 9.54% | 00.0% | Unchanged |
| State Street Corp | 2,571,570 | $87.9M | 0.00% | +557,591+27.7% | Added |
| RTW Investments, LP | 2,599,822 | $88.9M | 1.30% | +846,127+48.2% | Added |
| EcoR1 Capital, LLC | 2,639,706 | $90.3M | 2.89% | +1,195,906+82.8% | Added |
| BlackRock Inc. | 3,281,636 | $112.2M | 0.00% | +82,140+2.6% | Added |
| BVF Inc | 3,651,759 | $124.9M | 4.53% | −250,000−6.4% | Reduced |
| FMR LLC | 6,847,277 | $234.2M | 0.02% | +354,639+5.5% | Added |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −260,379−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −131,282−100.0% | Sold out |
| Jabodon PT Co | 0 | $0 | 0.00% | −90,656−100.0% | Sold out |
| Sio Capital Management, LLC | 0 | $0 | 0.00% | −90,000−100.0% | Sold out |
| State of New Jersey Common Pension Fund D | 0 | $0 | 0.00% | −54,589−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −40,387−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −35,000−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −23,876−100.0% | Sold out |
| Martingale Asset Management L P | 0 | $0 | 0.00% | −17,408−100.0% | Sold out |
| Bellwether Advisors, LLC | 0 | $0 | 0.00% | −13,630−100.0% | Sold out |
| Bingham Osborn & Scarborough LLC | 0 | $0 | 0.00% | −11,640−100.0% | Sold out |
| SG3 Management, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Lindbrook Capital, LLC | 0 | $0 | 0.00% | −2,450−100.0% | Sold out |
| O'Shaughnessy Asset Management, LLC | 0 | $0 | 0.00% | −2,162−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −1,800−100.0% | Sold out |
| Penserra Capital Management LLC | 0 | $0 | 0.00% | −1,090−100.0% | Sold out |
| Harbour Investments, Inc. | 0 | $0 | 0.00% | −126−100.0% | Sold out |
| Ellevest, Inc. | 0 | $0 | 0.00% | −6−100.0% | Sold out |
| State of Wyoming | 0 | $0 | 0.00% | −26−100.0% | Sold out |