Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2021
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 149
- +17 vs. Q3 2021
- Shares held
- 49.4M
- +3.04M (+6.6%) vs. Q3 2021
- Total value
- $1.68B
- +$863.7M (+105.2%) vs. Q3 2021
- New holders
- 36
- 58 more added
- Sold out
- 19
- 36 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 14 | $0 | 0.00% | +14 | New |
| Northwestern Mutual Wealth Management Co | 16 | $1.00K | 0.00% | +16 | New |
| Signaturefd, LLC | 46 | $2.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 57 | $2.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 163 | $6.00K | 0.00% | 00.0% | Unchanged |
| TCI Wealth Advisors, Inc. | 219 | $7.00K | 0.00% | +73+50.0% | Added |
| Truvestments Capital LLC | 250 | $9.00K | 0.00% | 00.0% | Unchanged |
| Macquarie Group Ltd | 307 | $10.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 278 | $10.0K | 0.00% | +14+5.3% | Added |
| Leonteq Securities AG | 470 | $16.1K | 0.00% | +470 | New |
| Cubist Systematic Strategies, LLC | 546 | $19.0K | 0.00% | −571−51.1% | Reduced |
| Cutler Group LP | 584 | $19.0K | 0.00% | +484+484.0% | Added |
| Eagle Bay Advisors LLC | 1,000 | $34.0K | 0.02% | −240−19.4% | Reduced |
| Captrust Financial Advisors | 1,153 | $39.0K | 0.00% | +1,110+2,581.4% | Added |
| Central Trust Co | 1,625 | $56.0K | 0.00% | +1,625 | New |
| Simplex Trading, LLC | 1,804 | $61.0K | 0.00% | +1,804 | New |
| Great West Life Assurance Co | 1,982 | $68.0K | 0.00% | 00.0% | Unchanged |
| Cowen and Company, LLC | 3,178 | $109.0K | 0.01% | +3,178 | New |
| Ameritas Investment Partners, Inc. | 3,501 | $120.0K | 0.00% | +260+8.0% | Added |
| Amundi | 4,053 | $141.0K | 0.00% | +4,053 | New |
| Kessler Investment Group, LLC | 5,165 | $177.0K | 0.10% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 5,521 | $189.0K | 0.07% | +351+6.8% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 6,293 | $215.0K | 0.00% | +3,864+159.1% | Added |
| Panagora Asset Management Inc | 7,225 | $247.0K | 0.00% | −24,212−77.0% | Reduced |
| Coastal Bridge Advisors, LLC | 7,400 | $254.0K | 0.05% | +7,400 | New |
| Gladstone Institutional Advisory LLC | 7,506 | $257.0K | 0.02% | +7,506 | New |
| Principal Financial Group Inc | 7,607 | $260.0K | 0.00% | +7,607 | New |
| Kestra Advisory Services, LLC | 7,833 | $268.0K | 0.00% | +7,833 | New |
| Amalgamated Bank | 7,879 | $269.0K | 0.00% | +7,879 | New |
| Janus Henderson Group PLC | 8,014 | $274.0K | 0.00% | +8,014 | New |
| Teacher Retirement System of Texas | 8,464 | $289.0K | 0.00% | +8,464 | New |
| Tower Research Capital LLC (TRC) | 8,835 | $302.0K | 0.01% | −3,298−27.2% | Reduced |
| Victory Capital Management Inc | 9,612 | $329.0K | 0.00% | +9,612 | New |
| Royal Bank of Canada | 10,067 | $345.0K | 0.00% | +5,282+110.4% | Added |
| Belvedere Trading LLC | 11,948 | $350.0K | 0.08% | +763+6.8% | Added |
| Ensign Peak Advisors, Inc | 10,680 | $365.0K | 0.00% | +10,680 | New |
| State Board of Administration of Florida Retirement System | 10,953 | $375.0K | 0.00% | +125+1.2% | Added |
| Arizona State Retirement System | 11,518 | $394.0K | 0.00% | +745+6.9% | Added |
| Metropolitan Life Insurance Co | 11,747 | $401.7K | 0.01% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 14,400 | $439.0K | 0.00% | +400+2.9% | Added |
| Quantbot Technologies LP | 13,104 | $448.0K | 0.04% | +13,104 | New |
| STRS Ohio | 13,200 | $451.0K | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 15,088 | $516.0K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 15,177 | $519.0K | 0.00% | −26,500−63.6% | Reduced |
| Putnam Investments LLC | 15,484 | $529.0K | 0.00% | +15,484 | New |
| PDT Partners, LLC | 16,018 | $548.0K | 0.04% | −13,682−46.1% | Reduced |
| ProShare Advisors LLC | 16,489 | $564.0K | 0.00% | +597+3.8% | Added |
| Voya Investment Management LLC | 17,368 | $594.0K | 0.00% | −69−0.4% | Reduced |
| Susquehanna Fundamental Investments, LLC | 18,524 | $634.0K | 0.02% | +5,509+42.3% | Added |
| Harvest Investment Services, LLC | 18,627 | $637.0K | 0.27% | −2,280−10.9% | Reduced |
| Gyon Technologies Capital Management, LP | 18,882 | $646.0K | 0.12% | +18,882 | New |
| HAP Trading, LLC | 19,166 | $655.0K | 0.05% | −1,743−8.3% | Reduced |
| Invesco Ltd. | 19,825 | $678.0K | 0.00% | −2,627−11.7% | Reduced |
| Vontobel Holding Ltd. | 20,000 | $684.0K | 0.01% | 00.0% | Unchanged |
| Legal & General Group Plc | 21,264 | $727.0K | 0.00% | +632+3.1% | Added |
| Bank of Montreal | 21,400 | $734.0K | 0.00% | −405−1.9% | Reduced |
| King Wealth | 22,000 | $752.0K | 0.14% | 00.0% | Unchanged |
| Franklin Street Advisors Inc | 22,220 | $760.0K | 0.06% | 00.0% | Unchanged |
| Parametric Portfolio Associates LLC | 22,651 | $775.0K | 0.00% | +2,217+10.8% | Added |
| Manufacturers Life Insurance Company, The | 22,822 | $781.0K | 0.00% | −759−3.2% | Reduced |
| Nisa Investment Advisors, LLC | 27,150 | $795.0K | 0.01% | +26,700+5,933.3% | Added |
| American International Group, Inc. | 23,772 | $813.0K | 0.00% | −711−2.9% | Reduced |
| Allspring Global Investments Holdings, LLC | 25,371 | $867.0K | 0.00% | +25,371 | New |
| Bamco Inc | 26,000 | $889.0K | 0.00% | +26,000 | New |
| Two Sigma Investments, LP | 28,100 | $961.0K | 0.00% | +3,500+14.2% | Added |
| Credit Suisse AG | 28,348 | $969.0K | 0.00% | +653+2.4% | Added |
| Prudential Financial Inc | 30,105 | $1.03M | 0.00% | −190−0.6% | Reduced |
| HighVista Strategies LLC | 30,999 | $1.06M | 0.84% | +2,688+9.5% | Added |
| UBS Asset Management Americas Inc | 32,664 | $1.12M | 0.00% | +5,066+18.4% | Added |
| TD Asset Management Inc | 33,042 | $1.13M | 0.00% | −14,000−29.8% | Reduced |
| New York State Common Retirement Fund | 33,161 | $1.13M | 0.00% | +3,223+10.8% | Added |
| Citadel Advisors LLC | 35,548 | $1.22M | 0.00% | −83,156−70.1% | Reduced |
| Jump Financial, LLC | 37,100 | $1.27M | 0.08% | +37,100 | New |
| Birchview Capital, LP | 38,000 | $1.30M | 0.84% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 38,304 | $1.31M | 0.01% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 38,550 | $1.32M | 0.01% | +19,184+99.1% | Added |
| BNP Paribas Arbitrage, SA | 38,658 | $1.32M | 0.00% | +30,651+382.8% | Added |
| Two Sigma Advisers, LP | 38,800 | $1.33M | 0.00% | −106,500−73.3% | Reduced |
| Wells Fargo & Company | 40,358 | $1.38M | 0.00% | −18,371−31.3% | Reduced |
| D. E. Shaw & Co., Inc. | 43,286 | $1.48M | 0.00% | −72,627−62.7% | Reduced |
| Rhumbline Advisers | 43,969 | $1.50M | 0.00% | +1,274+3.0% | Added |
| Alliancebernstein L.P. | 45,900 | $1.57M | 0.00% | 00.0% | Unchanged |
| Nuveen Asset Management, LLC | 239,929 | $1.85M | 0.00% | +76,843+47.1% | Added |
| Resolute Capital Asset Partners LLC | 55,000 | $1.88M | 1.23% | +55,000 | New |
| Alps Advisors Inc | 55,232 | $1.89M | 0.02% | +55,232 | New |
| California State Teachers Retirement System | 60,465 | $2.07M | 0.00% | +3,957+7.0% | Added |
| Squarepoint Ops LLC | 60,490 | $2.07M | 0.01% | +60,490 | New |
| State of Wisconsin Investment Board | 64,600 | $2.21M | 0.00% | −6,600−9.3% | Reduced |
| UBS Group AG | 66,311 | $2.27M | 0.00% | −2,904−4.2% | Reduced |
| Industrial Alliance Investment Management Inc. | 75,235 | $2.57M | 0.06% | +75,235 | New |
| Jane Street Group, LLC | 76,396 | $2.61M | 0.01% | +18,542+32.0% | Added |
| Candriam Luxembourg S.C.A. | 83,646 | $2.86M | 0.02% | 00.0% | Unchanged |
| Swiss National Bank | 94,200 | $3.22M | 0.00% | +6,800+7.8% | Added |
| Walleye Capital LLC | 97,998 | $3.35M | 0.11% | +87,882+868.7% | Added |
| Alberta Investment Management Corp | 100,000 | $3.42M | 0.02% | +100,000 | New |
| Tekla Capital Management LLC | 101,037 | $3.46M | 0.11% | +14,800+17.2% | Added |
| Kennedy Capital Management, Inc. | 105,394 | $3.60M | 0.08% | −6,871−6.1% | Reduced |
| Morgan Stanley | 107,416 | $3.67M | 0.00% | −366,899−77.4% | Reduced |
| Silvercrest Asset Management Group LLC | 118,715 | $4.06M | 0.03% | +47,372+66.4% | Added |
| Bank of America Corp | 119,607 | $4.09M | 0.00% | +61,956+107.5% | Added |