Karyopharm Therapeutics Inc.
KPTI- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 3 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Karyopharm Therapeutics Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 120
- 0 vs. Q3 2023
- Shares held
- 73.5M
- −3.74M (−4.8%) vs. Q3 2023
- Total value
- $63.5M
- −$39.3M (−38.2%) vs. Q3 2023
- New holders
- 23
- 24 more added
- Sold out
- 23
- 42 more reduced
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KPTI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 96 | $206.8M |
| Q1 2026 | 77 | $98.4M |
| Q4 2025 | 68 | $69.6M |
| Q3 2025 | 52 | $19.5M |
| Q2 2025 | 50 | $19.0M |
| Q1 2025 | 50 | $13.7M |
| Q4 2024 | 87 | $41.2M |
| Q3 2024 | 91 | $49.2M |
| Q2 2024 | 114 | $58.6M |
| Q1 2024 | 114 | $113.0M |
| Q4 2023 | 120 | $63.5M |
| Q3 2023 | 120 | $102.8M |
| Q2 2023 | 138 | $145.0M |
| Q1 2023 | 132 | $340.1M |
| Q4 2022 | 155 | $334.4M |
| Q3 2022 | 147 | $364.1M |
| Q2 2022 | 150 | $302.8M |
| Q1 2022 | 139 | $501.8M |
| Q4 2021 | 143 | $347.5M |
| Q3 2021 | 134 | $334.4M |
| Q2 2021 | 154 | $608.7M |
| Q1 2021 | 171 | $637.1M |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Karyopharm Therapeutics Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Virtu Financial LLC | 10,007 | $9.00K | 0.00% | +10,007 | New |
| Russell Investments Group, Ltd. | 6,519 | $5.64K | 0.00% | −88,339−93.1% | Reduced |
| Advisor Group Holdings, Inc. | 6,444 | $5.57K | 0.00% | −500−7.2% | Reduced |
| Ameritas Investment Partners, Inc. | 6,194 | $5.36K | 0.00% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 4,684 | $4.05K | 0.00% | +4,684 | New |
| The PNC Financial Services Group, Inc. | 3,000 | $2.60K | 0.00% | 00.0% | Unchanged |
| Founders Capital Management | 2,000 | $1.73K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 2,060 | $1.70K | 0.00% | 00.0% | Unchanged |
| MB, Levis & Associates, LLC | 1,500 | $1.30K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 1,300 | $1.13K | 0.00% | 00.0% | Unchanged |
| AdvisorNet Financial, Inc | 700 | $606 | 0.00% | 00.0% | Unchanged |
| Bruce G. Allen Investments, LLC | 507 | $439 | 0.00% | +507 | New |
| Allworth Financial LP | 500 | $433 | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 500 | $433 | 0.00% | +500 | New |
| Kelly Financial Services LLC | 250 | $216 | 0.00% | 00.0% | Unchanged |
| West Branch Capital LLC | 48 | $42 | 0.00% | +48 | New |
| JJJ Advisors Inc. | 17 | $15 | 0.00% | +17 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 6 | $5 | 0.00% | 00.0% | Unchanged |
| Sofos Investments, Inc. | 2 | $2 | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 3 | $0 | 0.00% | +3 | New |
| AIGH Capital Management LLC | 0 | $0 | 0.00% | −1,773,474−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −1,397,543−100.0% | Sold out |
| Parkwood LLC | 0 | $0 | 0.00% | −1,000,000−100.0% | Sold out |
| Worth Venture Partners, LLC | 0 | $0 | 0.00% | −445,981−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −120,000−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −84,432−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −82,309−100.0% | Sold out |
| MetLife Investment Management | 0 | $0 | 0.00% | −60,235−100.0% | Sold out |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −47,088−100.0% | Sold out |
| Centiva Capital, LP | 0 | $0 | 0.00% | −45,790−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −34,154−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −22,824−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −21,699−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −19,433−100.0% | Sold out |
| Allspring Global Investments Holdings, LLC | 0 | $0 | 0.00% | −14,964−100.0% | Sold out |
| Headlands Technologies LLC | 0 | $0 | 0.00% | −13,817−100.0% | Sold out |
| Victory Capital Management Inc | 0 | $0 | 0.00% | −11,436−100.0% | Sold out |
| Metropolitan Life Insurance Co | 0 | $0 | 0.00% | −6,242−100.0% | Sold out |
| PEAK6 Investments LLC | 0 | $0 | 0.00% | −4,552−100.0% | Sold out |
| China Universal Asset Management Co., Ltd. | 0 | $0 | 0.00% | −2,929−100.0% | Sold out |
| Nisa Investment Advisors, LLC | 0 | $0 | 0.00% | −800−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −272−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −138−100.0% | Sold out |