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Karyopharm Therapeutics Inc.

KPTI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001503802

In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 2 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $213.5M in total; no superinvestor holds it.

Open-market trades, last 90 days

Open-market purchases (P) and sales (S) by Karyopharm Therapeutics Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.

Open-market buys
0 filings
Open-market sells
2 filings
2 insiders, $1.38K in total
Insiders trading
2
Net value
−$1.38K
Purchases minus sales

Insider roster

Directors, officers and 10% owners who have filed a Form 4 for Karyopharm Therapeutics Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.

Insider roster for Karyopharm Therapeutics Inc.
NameTitleLast reported holdingLast filingFilings, past year
Abate KristinChief Accounting Officer23,782Sep 2, 20267
Poulton StuartEVP, Chief Development Officer94,632Jul 30, 20266
Bohlin Garen GDirector18,517May 26, 20261
Pakianathan DeepikaDirector15,508May 26, 20261
Greene Barry EDirector16,415May 26, 20261
Schor ChenDirector15,508May 26, 20261
Oliger Christy J.Director15,508May 26, 20261
Su ZhenDirector15,508May 26, 20261
Paulson Richard A.President and CEO269,747May 15, 20264
Rangwala ReshmaEVP & Chief Medical Officer56,829May 15, 20264
Mano MichaelEVP, CLO&Secretary94,398May 15, 20264
Cheng Sohanya RoshanEVP & Chief Commercial Officer107,940May 15, 20264
Macomber LoriEVP, CFO & Treasurer85,105Feb 4, 20263
Mirza Mansoor RazaDirector–May 29, 20250
Mason MichaelEVP, CFO & Treasurer391,054Sep 5, 20240
Honig PeterDirector–May 25, 20230
Mitchener StephenSVP, Chief Business Officer128,313Mar 2, 20230
Shacham SharonChief Scientific Officer958,131Mar 31, 20220
Kauffman MichaelDirector898,131IndirectMar 2, 20220
Frenkel RanEVP, Chief Dev. Officer168,290Mar 2, 20220
Shah JatinEVP, Chief Medical Officer129,450Feb 22, 20220

Insider trades

Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 2, 2026 (view filing)4:57 PM ETSep 11 dayAbate KristinChief Accounting OfficerSSale−19$2.02−$38.38−0.1%23.8K after
Jul 30, 2026 (view filing)4:42 PM ETJul 282 daysPoulton StuartEVP, Chief Development OfficerSSale−189$7.10−$1.34K−0.2%94.6K after
May 15, 2026 (view filing)May 141 dayPoulton StuartEVP, Chief Development OfficerSSale−403$9.50−$3.83K−0.4%94.8K after
May 15, 2026 (view filing)May 141 dayRangwala ReshmaEVP & Chief Medical OfficerSSale−408$9.50−$3.88K−0.7%56.8K after
May 15, 2026 (view filing)May 141 dayCheng Sohanya RoshanEVP & Chief Commercial OfficerSSale−324$9.50−$3.08K−0.3%107.9K after
May 15, 2026 (view filing)May 141 dayAbate KristinChief Accounting OfficerSSale−53$9.50−$503.5−0.2%23.8K after
May 15, 2026 (view filing)May 141 dayPaulson Richard A.President and CEOSSale−2.20K$9.50−$20.9K−0.8%269.7K after
May 15, 2026 (view filing)May 141 dayMano MichaelEVP, CLO&SecretarySSale−266$9.50−$2.53K−0.3%94.4K after
Apr 22, 2026 (view filing)Apr 211 dayRangwala ReshmaEVP & Chief Medical OfficerSSale−449$8.94−$4.01K−0.8%56.3K after
Mar 3, 2026 (view filing)Mar 21 dayAbate KristinChief Accounting OfficerSSale−559$9.41−$5.26K−2.5%22.1K after
Mar 3, 2026 (view filing)Mar 21 dayPoulton StuartEVP, Chief Development OfficerSSale−5.10K$9.41−$48.0K−5.1%94.3K after
Mar 3, 2026 (view filing)Mar 21 dayCheng Sohanya RoshanEVP & Chief Commercial OfficerSSale−4.60K$9.41−$43.3K−4.1%107.3K after
Mar 3, 2026 (view filing)Mar 21 dayMano MichaelEVP, CLO&SecretarySSale−3.53K$9.41−$33.2K−3.6%94.0K after
Mar 3, 2026 (view filing)Mar 21 dayRangwala ReshmaEVP & Chief Medical OfficerSSale−5.07K$9.41−$47.7K−8.2%56.7K after
Mar 3, 2026 (view filing)Mar 21 dayPaulson Richard A.President and CEOSSale−12.4K$9.41−$116.3K−4.4%267.0K after
Feb 19, 2026 (view filing)Feb 172 daysPoulton StuartEVP, Chief Development OfficerSSale−378$8.63−$3.26K−0.4%99.4K after
Feb 4, 2026 (view filing)Feb 31 dayMacomber LoriEVP, CFO & TreasurerSSale−1.63K$6.30−$10.2K−1.9%85.1K after
Jan 29, 2026 (view filing)Jan 281 dayAbate KristinChief Accounting OfficerSSale−50$7.03−$351.5−0.2%22.6K after
Jan 22, 2026 (view filing)Jan 211 dayAbate KristinChief Accounting OfficerSSale−265$5.96−$1.58K−1.2%22.6K after
Oct 3, 2025 (view filing)Oct 12 daysAbate KristinChief Accounting OfficerSSale−362$6.30−$2.28K−3.5%10.0K after
Sep 16, 2025 (view filing)Sep 151 dayPaulson Richard A.President and CEOSSale−1.26K$6.43−$8.08K−1.5%84.0K after
Sep 16, 2025 (view filing)Sep 151 dayMano MichaelSVP, General Counsel&SecretarySSale−234$6.43−$1.50K−1.1%21.4K after
Sep 16, 2025 (view filing)Sep 151 dayPoulton StuartEVP, Chief Development OfficerSSale−401$6.43−$2.58K−1.4%27.7K after
Sep 16, 2025 (view filing)Sep 151 dayRangwala ReshmaEVP & Chief Medical OfficerSSale−408$6.43−$2.62K−1.4%29.4K after
Sep 16, 2025 (view filing)Sep 151 dayCheng Sohanya RoshanEVP & Chief Commercial OfficerSSale−325$6.43−$2.09K−0.9%35.9K after
Sep 16, 2025 (view filing)Sep 151 dayAbate KristinChief Accounting OfficerSSale−23$6.43−$147.89−0.2%10.4K after
Sep 4, 2025 (view filing)Sep 31 dayAbate KristinChief Accounting OfficerSSale−12$6.78−$81.36−0.1%9.46K after
Jul 30, 2025 (view filing)Jul 291 dayPoulton StuartEVP, Chief Development OfficerSSale−191$4.37−$834.67−0.7%27.2K after
Jul 23, 2025 (view filing)Jul 221 dayAbate KristinChief Accounting OfficerSSale−238$4.00−$952−2.5%9.47K after
May 7, 2025 (view filing)May 61 dayPaulson Richard A.President and CEOSSale−236$7.12−$1.68K−0.3%82.5K after
Apr 24, 2025 (view filing)Apr 231 dayRangwala ReshmaEVP & Chief Medical OfficerSSale−419$6.17−$2.59K−1.4%28.9K after
Apr 7, 2025 (view filing)Apr 43 daysPaulson Richard A.President and CEOSSale−245$3.74−$916.3−0.3%82.7K after
Mar 6, 2025 (view filing)Mar 42 daysCheng Sohanya RoshanEVP & Chief Commercial OfficerSSale−3.44K$6.29−$21.7K−9.1%34.3K after
Mar 6, 2025 (view filing)Mar 42 daysPaulson Richard A.President and CEOSSale−11.7K$6.29−$73.6K−12.4%83.0K after
Mar 6, 2025 (view filing)Mar 42 daysRangwala ReshmaEVP & Chief Medical OfficerSSale−3.59K$6.29−$22.6K−10.9%29.3K after
Mar 6, 2025 (view filing)Mar 42 daysPoulton StuartEVP, Chief Development OfficerSSale−3.55K$6.29−$22.3K−11.5%27.4K after
Mar 6, 2025 (view filing)Mar 42 daysAbate KristinChief Accounting OfficerSSale−571$6.29−$3.59K−5.6%9.71K after
Mar 6, 2025 (view filing)Mar 42 daysMano MichaelSVP, General Counsel&SecretarySSale−2.79K$6.29−$17.6K−11.7%21.0K after
Feb 19, 2025 (view filing)Feb 181 dayPoulton StuartEVP, Chief Development OfficerSSale−5.91K$0.63−$3.73K−1.8%320.7K after
Feb 5, 2025 (view filing)Feb 41 dayPaulson Richard A.President and CEOSSale−4.10K$0.65−$2.66K−0.4%1.12M after
Jan 7, 2025 (view filing)Jan 61 dayPaulson Richard A.President and CEOSSale−4.05K$0.78−$3.16K−0.4%1.12M after
Dec 5, 2024 (view filing)Dec 41 dayPaulson Richard A.President and CEOSSale−3.62K$0.81−$2.93K−0.3%1.13M after
Nov 6, 2024 (view filing)Nov 51 dayPaulson Richard A.President and CEOSSale−3.67K$0.91−$3.34K−0.3%1.13M after
Oct 7, 2024 (view filing)Oct 43 daysPaulson Richard A.President and CEOSSale−3.61K$0.88−$3.17K−0.3%1.14M after
Sep 5, 2024 (view filing)Sep 41 dayMano MichaelSVP, General Counsel&SecretarySSale−3.97K$0.72−$2.86K−1.4%273.9K after
Sep 5, 2024 (view filing)Sep 41 dayPaulson Richard A.President and CEOSSale−3.67K$0.72−$2.64K−0.3%1.14M after
Sep 5, 2024 (view filing)Sep 41 dayMason MichaelEVP, CFO & TreasurerSSale−7.05K$0.72−$5.08K−1.8%391.1K after
Sep 5, 2024 (view filing)Sep 41 dayCheng Sohanya RoshanEVP & Chief Commercial OfficerSSale−5.36K$0.72−$3.86K−1.3%404.1K after
Aug 8, 2024 (view filing)Aug 62 daysPaulson Richard A.President and CEOSSale−3.61K$0.93−$3.36K−0.3%1.14M after
Jul 31, 2024 (view filing)Jul 301 dayPoulton StuartEVP, Chief Development OfficerSSale−2.88K$1.06−$3.06K−0.9%326.6K after