Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.07 億；沒有大師持有。
2023 年第 4 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2023/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 120
- 較 2023 年第 3 季 0 家
- 持有股數
- 7,348 萬
- 較 2023 年第 3 季 −374.3 萬 (−4.8%)
- 總市值
- $6,348 萬
- 較 2023 年第 3 季 −$3,932 萬 (−38.2%)
- 新進機構
- 23
- 另有 24 家加碼
- 清倉機構
- 23
- 另有 42 家減碼
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.07 億 |
| 2026 年第 1 季 | 77 | $9,840 萬 |
| 2025 年第 4 季 | 68 | $6,960 萬 |
| 2025 年第 3 季 | 52 | $1,946 萬 |
| 2025 年第 2 季 | 50 | $1,902 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,120 萬 |
| 2024 年第 3 季 | 91 | $4,922 萬 |
| 2024 年第 2 季 | 114 | $5,863 萬 |
| 2024 年第 1 季 | 114 | $1.13 億 |
| 2023 年第 4 季 | 120 | $6,348 萬 |
| 2023 年第 3 季 | 120 | $1.03 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.40 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.47 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2023 年第 4 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2023 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock Inc. | 10,071,677 | $871.2 萬 | 0.00% | −1,014,856−9.2% | 減碼 |
| Vanguard Group Inc | 8,710,158 | $753.4 萬 | 0.00% | −109,771−1.2% | 減碼 |
| Avidity Partners Management LP | 8,298,570 | $717.8 萬 | 0.27% | 00.0% | 不變 |
| Palo Alto Investors LP | 5,102,193 | $441.3 萬 | 0.40% | −573,683−10.1% | 減碼 |
| Citadel Advisors LLC | 3,101,399 | $268.3 萬 | 0.00% | −2,489−0.1% | 減碼 |
| Geode Capital Management, LLC | 2,382,428 | $206.1 萬 | 0.00% | +95,282+4.2% | 加碼 |
| Gsa Capital Partners LLP | 2,337,985 | $202.2 萬 | 0.17% | +1,769,687+311.4% | 加碼 |
| State Street Corp | 2,053,773 | $177.7 萬 | 0.00% | +10,768+0.5% | 加碼 |
| Renaissance Technologies LLC | 1,964,377 | $169.9 萬 | 0.00% | +1,233,977+168.9% | 加碼 |
| Marshall Wace, LLP | 1,926,782 | $165.7 萬 | 0.00% | −256,419−11.7% | 減碼 |
| BNP Paribas Arbitrage, SA | 1,769,184 | $153.0 萬 | 0.00% | +108,286+6.5% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 1,663,300 | $143.9 萬 | 0.00% | +1,663,300 | 新進 |
| Millennium Management LLC | 1,534,264 | $132.7 萬 | 0.00% | +416,356+37.2% | 加碼 |
| C WorldWide Group Holding A/S | 1,500,000 | $129.8 萬 | 0.02% | 00.0% | 不變 |
| Deutsche Bank AG | 1,327,008 | $115.4 萬 | 0.00% | +1,268,777+2,178.9% | 加碼 |
| Goldman Sachs Group Inc | 1,296,593 | $112.2 萬 | 0.00% | −618,454−32.3% | 減碼 |
| JPMorgan Chase & Co | 1,181,120 | $102.2 萬 | 0.00% | +39,994+3.5% | 加碼 |
| AlphaCentric Advisors LLC | 1,125,000 | $97.3 萬 | 0.65% | 00.0% | 不變 |
| Tejara Capital Ltd | 1,031,348 | $89.2 萬 | 0.37% | −46,040−4.3% | 減碼 |
| Northern Trust Corp | 996,147 | $86.2 萬 | 0.00% | +10,415+1.1% | 加碼 |
| Barclays PLC | 970,062 | $83.9 萬 | 0.00% | −182,236−15.8% | 減碼 |
| Morgan Stanley | 845,151 | $73.1 萬 | 0.00% | −199,320−19.1% | 減碼 |
| UBS Oconnor LLC | 802,327 | $69.4 萬 | 0.02% | −74,383−8.5% | 減碼 |
| Altium Capital Management LP | 740,000 | $64.0 萬 | 0.44% | 00.0% | 不變 |
| D. E. Shaw & Co., Inc. | 617,216 | $53.4 萬 | 0.00% | −5,639−0.9% | 減碼 |
| AQR Capital Management LLC | 598,142 | $51.7 萬 | 0.00% | +96,343+19.2% | 加碼 |
| Silverarc Capital Management, LLC | 561,955 | $48.6 萬 | 0.15% | 00.0% | 不變 |
| Candriam Luxembourg S.C.A. | 530,694 | $45.9 萬 | 0.00% | −610,000−53.5% | 減碼 |
| Bank of New York Mellon Corp | 497,202 | $43.0 萬 | 0.00% | −156,448−23.9% | 減碼 |
| Birchview Capital, LP | 469,832 | $40.6 萬 | 0.32% | −102,000−17.8% | 減碼 |
| UBS Group AG | 457,185 | $39.5 萬 | 0.00% | −449,460−49.6% | 減碼 |
| Nuveen Asset Management, LLC | 454,302 | $39.3 萬 | 0.00% | +1,896+0.4% | 加碼 |
| Ikarian Capital, LLC | 400,000 | $34.6 萬 | 0.09% | 00.0% | 不變 |
| Los Angeles Capital Management LLC | 391,540 | $33.9 萬 | 0.00% | +391,540 | 新進 |
| Macquarie Group Ltd | 380,000 | $32.9 萬 | 0.00% | 00.0% | 不變 |
| Ameriprise Financial Inc | 309,967 | $26.8 萬 | 0.00% | −47,011−13.2% | 減碼 |
| Charles Schwab Investment Management Inc | 309,909 | $26.8 萬 | 0.00% | +51,000+19.7% | 加碼 |
| Bank of America Corp | 306,455 | $26.5 萬 | 0.00% | −46,167−13.1% | 減碼 |
| Bridgeway Capital Management, LLC | 289,500 | $25.0 萬 | 0.01% | 00.0% | 不變 |
| Jacobs Levy Equity Management, Inc | 284,457 | $24.6 萬 | 0.00% | −2,069,071−87.9% | 減碼 |
| Jane Street Group, LLC | 275,460 | $23.8 萬 | 0.00% | +275,460 | 新進 |
| Acadian Asset Management LLC | 275,059 | $23.7 萬 | 0.00% | +275,059 | 新進 |
| FMR LLC | 268,286 | $23.2 萬 | 0.00% | +1,839+0.7% | 加碼 |
| Panagora Asset Management Inc | 227,445 | $19.7 萬 | 0.00% | +227,445 | 新進 |
| Atom Investors LP | 216,690 | $18.7 萬 | 0.03% | +25,865+13.6% | 加碼 |
| Alliancebernstein L.P. | 192,810 | $16.7 萬 | 0.00% | 00.0% | 不變 |
| DAFNA Capital Management LLC | 192,678 | $16.7 萬 | 0.04% | 00.0% | 不變 |
| Two Sigma Investments, LP | 142,274 | $12.3 萬 | 0.00% | +142,274 | 新進 |
| Rhumbline Advisers | 138,107 | $11.9 萬 | 0.00% | −500.0% | 減碼 |
| Woodline Partners LP | 116,718 | $10.1 萬 | 0.00% | −17,394−13.0% | 減碼 |
| Exchange Traded Concepts, LLC | 115,864 | $10.0 萬 | 0.00% | +29,380+34.0% | 加碼 |
| Price T Rowe Associates Inc | 87,113 | $7.60 萬 | 0.00% | 00.0% | 不變 |
| Boothbay Fund Management, LLC | 81,736 | $7.07 萬 | 0.00% | 00.0% | 不變 |
| Susquehanna International Group, LLP | 78,596 | $6.80 萬 | 0.00% | −59,213−43.0% | 減碼 |
| Royal Bank of Canada | 76,320 | $6.60 萬 | 0.00% | −961−1.2% | 減碼 |
| SG Americas Securities, LLC | 73,430 | $6.40 萬 | 0.00% | +54,839+295.0% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 71,224 | $6.16 萬 | 0.00% | +35,945+101.9% | 加碼 |
| Two Sigma Advisers, LP | 63,200 | $5.47 萬 | 0.00% | +28,000+79.5% | 加碼 |
| American International Group, Inc. | 56,295 | $4.87 萬 | 0.00% | −228−0.4% | 減碼 |
| XTX Topco Ltd | 49,122 | $4.25 萬 | 0.01% | −260,943−84.2% | 減碼 |
| Voya Investment Management LLC | 45,471 | $3.93 萬 | 0.00% | 00.0% | 不變 |
| Wade G W & Inc | 45,140 | $3.90 萬 | 0.00% | 00.0% | 不變 |
| HSBC Holdings PLC | 45,290 | $3.89 萬 | 0.00% | +362+0.8% | 加碼 |
| Monashee Investment Management LLC | 132,435 | $3.49 萬 | 0.01% | +132,435 | 新進 |
| Sawtooth Solutions, LLC | 37,938 | $3.28 萬 | 0.00% | +37,938 | 新進 |
| Bleakley Financial Group, LLC | 37,938 | $3.28 萬 | 0.00% | +37,938 | 新進 |
| Kennedy Investment Group | 35,000 | $3.03 萬 | 0.02% | 00.0% | 不變 |
| Principal Financial Group Inc | 31,442 | $2.72 萬 | 0.00% | −1,396−4.3% | 減碼 |
| Group One Trading, L.P. | 30,473 | $2.64 萬 | 0.00% | −24,040−44.1% | 減碼 |
| Redwood Wealth Management Group, LLC | 29,730 | $2.57 萬 | 0.03% | −3,000−9.2% | 減碼 |
| State Board of Administration of Florida Retirement System | 29,422 | $2.54 萬 | 0.00% | +29,422 | 新進 |
| Wells Fargo & Company | 29,365 | $2.54 萬 | 0.00% | +6,682+29.5% | 加碼 |
| Engineers Gate Manager LP | 28,700 | $2.48 萬 | 0.00% | −10,262−26.3% | 減碼 |
| Invesco Ltd. | 28,471 | $2.46 萬 | 0.00% | −35,341−55.4% | 減碼 |
| State of Wyoming | 28,431 | $2.46 萬 | 0.00% | −12,310−30.2% | 減碼 |
| Wexford Capital LP | 27,280 | $2.36 萬 | 0.01% | +27,280 | 新進 |
| Weiss Multi-Strategy Advisers LLC | 27,043 | $2.30 萬 | 0.00% | −4,771−15.0% | 減碼 |
| Banque Cantonale Vaudoise | 25,000 | $2.20 萬 | 0.00% | +10,000+66.7% | 加碼 |
| Prudential Financial Inc | 24,815 | $2.15 萬 | 0.00% | +5,400+27.8% | 加碼 |
| ELCO Management Co., LLC | 22,561 | $1.95 萬 | 0.01% | 00.0% | 不變 |
| Point72 Middle East FZE | 22,028 | $1.91 萬 | 0.00% | −73,110−76.8% | 減碼 |
| Simplex Trading, LLC | 21,001 | $1.80 萬 | 0.00% | −505−2.3% | 減碼 |
| Two Sigma Securities, LLC | 19,586 | $1.69 萬 | 0.00% | +19,586 | 新進 |
| New York State Common Retirement Fund | 19,373 | $1.68 萬 | 0.00% | −290−1.5% | 減碼 |
| ProShare Advisors LLC | 18,746 | $1.62 萬 | 0.00% | −3,445−15.5% | 減碼 |
| California State Teachers Retirement System | 18,642 | $1.61 萬 | 0.00% | −6,348−25.4% | 減碼 |
| Diversified Trust Co | 18,580 | $1.61 萬 | 0.00% | +18,580 | 新進 |
| Citigroup Inc | 16,432 | $1.42 萬 | 0.00% | +14,827+923.8% | 加碼 |
| Amalgamated Bank | 14,694 | $1.30 萬 | 0.00% | −737−4.8% | 減碼 |
| CI Private Wealth, LLC | 14,000 | $1.21 萬 | 0.00% | +14,000 | 新進 |
| Baird Financial Group, Inc. | 13,800 | $1.19 萬 | 0.00% | 00.0% | 不變 |
| Legal & General Group Plc | 13,735 | $1.19 萬 | 0.00% | 00.0% | 不變 |
| Neuberger Berman Group LLC | 13,317 | $1.15 萬 | 0.00% | +2,083+18.5% | 加碼 |
| Brinker Capital Investments, LLC | 10,965 | $1.01 萬 | 0.00% | −2,074−15.9% | 減碼 |
| Orion Portfolio Solutions, LLC | 10,965 | $1.01 萬 | 0.00% | −2,074−15.9% | 減碼 |
| Tower Research Capital LLC (TRC) | 11,616 | $1.00 萬 | 0.00% | −10,528−47.5% | 減碼 |
| Creative Planning | 11,600 | $1.00 萬 | 0.00% | 00.0% | 不變 |
| Bayesian Capital Management, LP | 11,100 | $9,602 | 0.00% | +11,100 | 新進 |
| Snowden Capital Advisors LLC | 11,000 | $9,515 | 0.00% | +11,000 | 新進 |
| Janney Montgomery Scott LLC | 10,000 | $9,000 | 0.00% | 00.0% | 不變 |