Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.07 億；沒有大師持有。
2024 年第 1 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2024/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 114
- 較 2023 年第 4 季 −4 家
- 持有股數
- 7,478 萬
- 較 2023 年第 4 季 +138.2 萬 (+1.9%)
- 總市值
- $1.13 億
- 較 2023 年第 4 季 +$4,955 萬 (+78.2%)
- 新進機構
- 18
- 另有 38 家加碼
- 清倉機構
- 22
- 另有 31 家減碼
另有 2 家機構在 2023 年第 4 季持有、還沒有申報 2024 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.07 億 |
| 2026 年第 1 季 | 77 | $9,840 萬 |
| 2025 年第 4 季 | 68 | $6,960 萬 |
| 2025 年第 3 季 | 52 | $1,946 萬 |
| 2025 年第 2 季 | 50 | $1,902 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,120 萬 |
| 2024 年第 3 季 | 91 | $4,922 萬 |
| 2024 年第 2 季 | 114 | $5,863 萬 |
| 2024 年第 1 季 | 114 | $1.13 億 |
| 2023 年第 4 季 | 120 | $6,348 萬 |
| 2023 年第 3 季 | 120 | $1.03 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.40 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.47 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2024 年第 1 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2023 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock Inc. | 9,447,678 | $1,427 萬 | 0.00% | −623,999−6.2% | 減碼 |
| Vanguard Group Inc | 8,338,401 | $1,259 萬 | 0.00% | −371,757−4.3% | 減碼 |
| Avidity Partners Management LP | 8,298,570 | $1,253 萬 | 0.45% | 00.0% | 不變 |
| Palo Alto Investors LP | 5,102,193 | $770.4 萬 | 0.87% | 00.0% | 不變 |
| Eversept Partners, LP | 5,016,320 | $757.5 萬 | 0.57% | +5,016,320 | 新進 |
| Adage Capital Partners GP, L.L.C. | 3,500,000 | $528.5 萬 | 0.01% | +1,836,700+110.4% | 加碼 |
| Citadel Advisors LLC | 3,105,069 | $468.9 萬 | 0.00% | +3,670+0.1% | 加碼 |
| Marshall Wace, LLP | 2,595,599 | $391.9 萬 | 0.01% | +668,817+34.7% | 加碼 |
| Geode Capital Management, LLC | 2,520,105 | $380.6 萬 | 0.00% | +137,677+5.8% | 加碼 |
| State Street Corp | 2,285,788 | $345.2 萬 | 0.00% | +232,015+11.3% | 加碼 |
| BNP Paribas Arbitrage, SA | 1,773,758 | $267.8 萬 | 0.00% | +4,574+0.3% | 加碼 |
| Goldman Sachs Group Inc | 1,508,262 | $227.7 萬 | 0.00% | +211,669+16.3% | 加碼 |
| C WorldWide Group Holding A/S | 1,500,000 | $226.5 萬 | 0.03% | 00.0% | 不變 |
| JPMorgan Chase & Co | 1,377,584 | $208.0 萬 | 0.00% | +196,464+16.6% | 加碼 |
| Deutsche Bank AG | 1,324,977 | $200.1 萬 | 0.00% | −2,031−0.2% | 減碼 |
| Gsa Capital Partners LLP | 1,299,151 | $196.2 萬 | 0.16% | −1,038,834−44.4% | 減碼 |
| Millennium Management LLC | 1,185,879 | $179.1 萬 | 0.00% | −348,385−22.7% | 減碼 |
| AlphaCentric Advisors LLC | 1,125,000 | $169.9 萬 | 1.02% | 00.0% | 不變 |
| D. E. Shaw & Co., Inc. | 962,825 | $145.4 萬 | 0.00% | +345,609+56.0% | 加碼 |
| Northern Trust Corp | 958,805 | $144.8 萬 | 0.00% | −37,342−3.7% | 減碼 |
| Renaissance Technologies LLC | 906,800 | $136.9 萬 | 0.00% | −1,057,577−53.8% | 減碼 |
| Barclays PLC | 892,815 | $134.8 萬 | 0.00% | −77,247−8.0% | 減碼 |
| Altium Capital Management LP | 740,000 | $111.7 萬 | 0.50% | 00.0% | 不變 |
| UBS Oconnor LLC | 722,327 | $109.1 萬 | 0.03% | −80,000−10.0% | 減碼 |
| Silverarc Capital Management, LLC | 558,466 | $84.3 萬 | 0.24% | −3,489−0.6% | 減碼 |
| Macquarie Group Ltd | 500,000 | $75.5 萬 | 0.00% | +120,000+31.6% | 加碼 |
| Nuveen Asset Management, LLC | 492,365 | $74.3 萬 | 0.00% | +38,063+8.4% | 加碼 |
| Bank of New York Mellon Corp | 487,060 | $73.5 萬 | 0.00% | −10,142−2.0% | 減碼 |
| Birchview Capital, LP | 469,832 | $70.9 萬 | 0.58% | 00.0% | 不變 |
| Ikarian Capital, LLC | 409,355 | $61.8 萬 | 0.17% | +9,355+2.3% | 加碼 |
| Los Angeles Capital Management LLC | 387,520 | $58.5 萬 | 0.00% | −4,020−1.0% | 減碼 |
| Charles Schwab Investment Management Inc | 309,909 | $46.8 萬 | 0.00% | 00.0% | 不變 |
| Morgan Stanley | 294,787 | $44.5 萬 | 0.00% | −550,364−65.1% | 減碼 |
| FMR LLC | 273,808 | $41.3 萬 | 0.00% | +5,522+2.1% | 加碼 |
| UBS Group AG | 254,933 | $38.5 萬 | 0.00% | −202,252−44.2% | 減碼 |
| Atom Investors LP | 244,397 | $36.9 萬 | 0.05% | +27,707+12.8% | 加碼 |
| XTX Topco Ltd | 242,841 | $36.7 萬 | 0.05% | +193,719+394.4% | 加碼 |
| Panagora Asset Management Inc | 229,924 | $34.7 萬 | 0.00% | +2,479+1.1% | 加碼 |
| Exchange Traded Concepts, LLC | 212,638 | $32.1 萬 | 0.01% | +96,774+83.5% | 加碼 |
| Alliancebernstein L.P. | 192,810 | $29.1 萬 | 0.00% | 00.0% | 不變 |
| DAFNA Capital Management LLC | 192,678 | $29.1 萬 | 0.07% | 00.0% | 不變 |
| Bridgeway Capital Management, LLC | 189,500 | $28.6 萬 | 0.01% | −100,000−34.5% | 減碼 |
| Jane Street Group, LLC | 171,650 | $25.9 萬 | 0.00% | −103,810−37.7% | 減碼 |
| Bank of America Corp | 157,915 | $23.8 萬 | 0.00% | −148,540−48.5% | 減碼 |
| Rhumbline Advisers | 144,028 | $21.7 萬 | 0.00% | +5,921+4.3% | 加碼 |
| Royal Bank of Canada | 137,012 | $20.7 萬 | 0.00% | +60,692+79.5% | 加碼 |
| Woodline Partners LP | 134,112 | $20.3 萬 | 0.00% | +17,394+14.9% | 加碼 |
| AQR Capital Management LLC | 125,826 | $19.0 萬 | 0.00% | −472,316−79.0% | 減碼 |
| Price T Rowe Associates Inc | 95,091 | $14.4 萬 | 0.00% | +7,978+9.2% | 加碼 |
| Boothbay Fund Management, LLC | 91,091 | $13.8 萬 | 0.00% | +9,355+11.4% | 加碼 |
| Susquehanna International Group, LLP | 76,599 | $11.6 萬 | 0.00% | −1,997−2.5% | 減碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 76,317 | $11.5 萬 | 0.00% | +5,093+7.2% | 加碼 |
| State Board of Administration of Florida Retirement System | 27,015 | $10.5 萬 | 0.00% | −2,407−8.2% | 減碼 |
| MetLife Investment Management | 60,551 | $9.14 萬 | 0.00% | +60,551 | 新進 |
| American International Group, Inc. | 55,816 | $8.43 萬 | 0.00% | −479−0.9% | 減碼 |
| Simplex Trading, LLC | 55,985 | $8.40 萬 | 0.00% | +34,984+166.6% | 加碼 |
| HSBC Holdings PLC | 53,563 | $8.09 萬 | 0.00% | +8,273+18.3% | 加碼 |
| State of Wyoming | 47,307 | $7.14 萬 | 0.01% | +18,876+66.4% | 加碼 |
| Bleakley Financial Group, LLC | 44,011 | $6.65 萬 | 0.00% | +6,073+16.0% | 加碼 |
| Simplicity Wealth,LLC | 44,011 | $6.65 萬 | 0.00% | +44,011 | 新進 |
| SEI Investments Co | 40,000 | $6.04 萬 | 0.00% | +40,000 | 新進 |
| Voya Investment Management LLC | 38,802 | $5.86 萬 | 0.00% | −6,669−14.7% | 減碼 |
| Group One Trading, L.P. | 37,132 | $5.61 萬 | 0.00% | +6,659+21.9% | 加碼 |
| Manufacturers Life Insurance Company, The | 35,868 | $5.42 萬 | 0.00% | +35,868 | 新進 |
| Kennedy Investment Group | 35,000 | $5.29 萬 | 0.03% | 00.0% | 不變 |
| Wells Fargo & Company | 33,898 | $5.12 萬 | 0.00% | +4,533+15.4% | 加碼 |
| Principal Financial Group Inc | 33,165 | $5.01 萬 | 0.00% | +1,723+5.5% | 加碼 |
| Colony Group, LLC | 45,930 | $5.00 萬 | 0.00% | +45,930 | 新進 |
| ELCO Management Co., LLC | 31,901 | $4.82 萬 | 0.03% | +9,340+41.4% | 加碼 |
| Eqis Capital Management, Inc. | 29,197 | $4.41 萬 | 0.00% | +29,197 | 新進 |
| Engineers Gate Manager LP | 28,700 | $4.33 萬 | 0.00% | 00.0% | 不變 |
| Invesco Ltd. | 27,969 | $4.22 萬 | 0.00% | −502−1.8% | 減碼 |
| Banque Cantonale Vaudoise | 25,000 | $3.80 萬 | 0.00% | 00.0% | 不變 |
| Commonwealth Equity Services, LLC | 25,406 | $3.80 萬 | 0.00% | +25,406 | 新進 |
| Prelude Capital Management, LLC | 23,500 | $3.55 萬 | 0.00% | +23,500 | 新進 |
| New York State Common Retirement Fund | 21,150 | $3.19 萬 | 0.00% | +1,777+9.2% | 加碼 |
| Baird Financial Group, Inc. | 20,800 | $3.14 萬 | 0.00% | +7,000+50.7% | 加碼 |
| ProShare Advisors LLC | 20,348 | $3.07 萬 | 0.00% | +1,602+8.5% | 加碼 |
| Prudential Financial Inc | 19,615 | $2.96 萬 | 0.00% | −5,200−21.0% | 減碼 |
| Citigroup Inc | 18,924 | $2.86 萬 | 0.00% | +2,492+15.2% | 加碼 |
| Diversified Trust Co | 18,580 | $2.81 萬 | 0.00% | 00.0% | 不變 |
| Winthrop Advisory Group LLC | 15,000 | $2.27 萬 | 0.00% | +15,000 | 新進 |
| CI Private Wealth, LLC | 13,900 | $2.10 萬 | 0.00% | −100−0.7% | 減碼 |
| Legal & General Group Plc | 13,735 | $2.07 萬 | 0.00% | 00.0% | 不變 |
| Two Sigma Investments, LP | 13,691 | $2.07 萬 | 0.00% | −128,583−90.4% | 減碼 |
| California State Teachers Retirement System | 11,387 | $1.72 萬 | 0.00% | −7,255−38.9% | 減碼 |
| Snowden Capital Advisors LLC | 11,000 | $1.66 萬 | 0.00% | 00.0% | 不變 |
| Two Sigma Securities, LLC | 10,208 | $1.54 萬 | 0.00% | −9,378−47.9% | 減碼 |
| Janney Montgomery Scott LLC | 10,000 | $1.50 萬 | 0.00% | 00.0% | 不變 |
| Advisor Group Holdings, Inc. | 8,595 | $1.30 萬 | 0.00% | +2,151+33.4% | 加碼 |
| Metropolitan Life Insurance Co | 6,231 | $9,409 | 0.00% | +6,231 | 新進 |
| Ameritas Investment Partners, Inc. | 6,194 | $9,353 | 0.00% | 00.0% | 不變 |
| The PNC Financial Services Group, Inc. | 3,000 | $4,530 | 0.00% | 00.0% | 不變 |
| Amalgamated Bank | 2,478 | $4,000 | 0.00% | −12,216−83.1% | 減碼 |
| Founders Capital Management | 2,000 | $3,020 | 0.00% | 00.0% | 不變 |
| Tower Research Capital LLC (TRC) | 1,637 | $2,472 | 0.00% | −9,979−85.9% | 減碼 |
| MB, Levis & Associates, LLC | 1,500 | $2,265 | 0.00% | 00.0% | 不變 |
| ADAR1 Capital Management, LLC | 1,479 | $2,233 | 0.00% | +1,479 | 新進 |
| Harbour Investments, Inc. | 1,300 | $1,963 | 0.00% | 00.0% | 不變 |
| Headlands Technologies LLC | 1,242 | $1,875 | 0.00% | +1,242 | 新進 |