Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.07 億；沒有大師持有。
2021 年第 4 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2021/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 143
- 較 2021 年第 3 季 +12 家
- 持有股數
- 5,418 萬
- 較 2021 年第 3 季 −95.5 萬 (−1.7%)
- 總市值
- $3.47 億
- 較 2021 年第 3 季 +$2,632 萬 (+8.2%)
- 新進機構
- 29
- 另有 51 家加碼
- 清倉機構
- 17
- 另有 46 家減碼
另有 3 家機構在 2021 年第 3 季持有、還沒有申報 2021 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.07 億 |
| 2026 年第 1 季 | 77 | $9,840 萬 |
| 2025 年第 4 季 | 68 | $6,960 萬 |
| 2025 年第 3 季 | 52 | $1,946 萬 |
| 2025 年第 2 季 | 50 | $1,902 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,120 萬 |
| 2024 年第 3 季 | 91 | $4,922 萬 |
| 2024 年第 2 季 | 114 | $5,863 萬 |
| 2024 年第 1 季 | 114 | $1.13 億 |
| 2023 年第 4 季 | 120 | $6,348 萬 |
| 2023 年第 3 季 | 120 | $1.03 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.40 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.47 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2021 年第 4 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2021 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock Inc. | 8,918,206 | $5,734 萬 | 0.00% | +127,888+1.5% | 加碼 |
| State Street Corp | 5,513,680 | $3,545 萬 | 0.00% | −2,506,319−31.3% | 減碼 |
| Palo Alto Investors LP | 5,470,452 | $3,518 萬 | 2.25% | +87,400+1.6% | 加碼 |
| Vanguard Group Inc | 3,358,807 | $2,160 萬 | 0.00% | −283,892−7.8% | 減碼 |
| Rubric Capital Management LP | 2,782,443 | $1,789 萬 | 0.85% | −593,315−17.6% | 減碼 |
| Alkeon Capital Management LLC | 1,961,588 | $1,261 萬 | 0.04% | 00.0% | 不變 |
| Frontier Capital Management Co LLC | 1,685,405 | $1,084 萬 | 0.09% | +582,978+52.9% | 加碼 |
| Lombard Odier Asset Management (Switzerland) SA | 1,658,047 | $1,066 萬 | 0.68% | +140,243+9.2% | 加碼 |
| Millennium Management LLC | 1,520,224 | $977.5 萬 | 0.01% | +1,520,224 | 新進 |
| C WorldWide Group Holding A/S | 1,500,000 | $964.5 萬 | 0.09% | +300,000+25.0% | 加碼 |
| Geode Capital Management, LLC | 1,442,731 | $927.6 萬 | 0.00% | +35,574+2.5% | 加碼 |
| Rice Hall James & Associates, LLC | 1,276,634 | $820.9 萬 | 0.29% | −125,227−8.9% | 減碼 |
| Morgan Stanley | 1,065,619 | $685.4 萬 | 0.00% | −827,314−43.7% | 減碼 |
| Nuveen Asset Management, LLC | 1,184,310 | $671.5 萬 | 0.00% | +65,302+5.8% | 加碼 |
| Goldman Sachs Group Inc | 1,028,882 | $661.5 萬 | 0.00% | +43,500+4.4% | 加碼 |
| Two Sigma Investments, LP | 989,031 | $635.9 萬 | 0.02% | −107,652−9.8% | 減碼 |
| Candriam Luxembourg S.C.A. | 877,668 | $564.3 萬 | 0.04% | +160,000+22.3% | 加碼 |
| Northern Trust Corp | 775,551 | $498.6 萬 | 0.00% | +8,491+1.1% | 加碼 |
| JPMorgan Chase & Co | 743,400 | $477.9 萬 | 0.00% | +278,479+59.9% | 加碼 |
| Susquehanna International Group, LLP | 602,826 | $387.7 萬 | 0.01% | +62,433+11.6% | 加碼 |
| Cubist Systematic Strategies, LLC | 563,530 | $362.3 萬 | 0.03% | +467,536+487.0% | 加碼 |
| Two Sigma Advisers, LP | 427,600 | $274.9 萬 | 0.01% | −654,400−60.5% | 減碼 |
| Hennion & Walsh Asset Management, Inc. | 393,692 | $253.1 萬 | 0.12% | −13,782−3.4% | 減碼 |
| Macquarie Group Ltd | 382,041 | $245.6 萬 | 0.00% | 00.0% | 不變 |
| Rafferty Asset Management, LLC | 380,568 | $244.7 萬 | 0.01% | +9,585+2.6% | 加碼 |
| Citigroup Inc | 304,098 | $195.5 萬 | 0.00% | +60,850+25.0% | 加碼 |
| Bank of New York Mellon Corp | 297,541 | $191.3 萬 | 0.00% | −4,960−1.6% | 減碼 |
| Parametric Portfolio Associates LLC | 277,519 | $178.4 萬 | 0.00% | −15,611−5.3% | 減碼 |
| J. Goldman & Co LP | 274,243 | $176.3 萬 | 0.16% | +216,517+375.1% | 加碼 |
| Jennison Associates LLC | 270,757 | $174.1 萬 | 0.00% | +665+0.2% | 加碼 |
| UBS Group AG | 266,995 | $171.7 萬 | 0.00% | −341,490−56.1% | 減碼 |
| Bank of America Corp | 254,868 | $164.0 萬 | 0.00% | +18,953+8.0% | 加碼 |
| HRT Financial LP | 248,332 | $159.6 萬 | 0.01% | +248,332 | 新進 |
| Birchview Capital, LP | 246,000 | $158.2 萬 | 1.02% | 00.0% | 不變 |
| Citadel Advisors LLC | 228,883 | $147.2 萬 | 0.00% | +8,106+3.7% | 加碼 |
| Trexquant Investment LP | 220,875 | $142.0 萬 | 0.09% | +184,674+510.1% | 加碼 |
| Tudor Investment Corp Et Al | 208,526 | $134.1 萬 | 0.03% | +15,595+8.1% | 加碼 |
| Jane Street Group, LLC | 207,143 | $133.2 萬 | 0.00% | +178,815+631.2% | 加碼 |
| Wellington Management Group LLP | 201,550 | $129.6 萬 | 0.00% | +201,550 | 新進 |
| Voloridge Investment Management, LLC | 197,391 | $126.9 萬 | 0.01% | +197,391 | 新進 |
| Gsa Capital Partners LLP | 191,976 | $123.4 萬 | 0.16% | +14,980+8.5% | 加碼 |
| Allianz Asset Management GmbH | 187,101 | $121.3 萬 | 0.00% | +54,153+40.7% | 加碼 |
| Charles Schwab Investment Management Inc | 188,149 | $121.0 萬 | 0.00% | 00.0% | 不變 |
| Barclays PLC | 181,752 | $116.9 萬 | 0.00% | +49,363+37.3% | 加碼 |
| D. E. Shaw & Co., Inc. | 176,051 | $113.2 萬 | 0.00% | +176,051 | 新進 |
| Swiss National Bank | 149,450 | $96.1 萬 | 0.00% | +17,800+13.5% | 加碼 |
| AlphaCentric Advisors LLC | 140,000 | $90.0 萬 | 0.26% | +4,000+2.9% | 加碼 |
| Squarepoint Ops LLC | 124,274 | $79.9 萬 | 0.00% | +124,274 | 新進 |
| Group One Trading, L.P. | 120,114 | $77.2 萬 | 0.01% | +73,460+157.5% | 加碼 |
| Alliancebernstein L.P. | 115,830 | $74.5 萬 | 0.00% | 00.0% | 不變 |
| ExodusPoint Capital Management, LP | 108,896 | $70.0 萬 | 0.01% | +78,976+264.0% | 加碼 |
| California State Teachers Retirement System | 96,698 | $62.2 萬 | 0.00% | +8,747+9.9% | 加碼 |
| State of Wisconsin Investment Board | 95,800 | $61.6 萬 | 0.00% | +400+0.4% | 加碼 |
| Rhumbline Advisers | 94,710 | $60.9 萬 | 0.00% | −1,481−1.5% | 減碼 |
| UBS Asset Management Americas Inc | 91,721 | $59.0 萬 | 0.00% | +7,328+8.7% | 加碼 |
| Renaissance Technologies LLC | 85,900 | $55.2 萬 | 0.00% | −409,500−82.7% | 減碼 |
| Jump Financial, LLC | 85,615 | $55.1 萬 | 0.03% | +85,615 | 新進 |
| Algert Global LLC | 78,239 | $50.3 萬 | 0.06% | −9,300−10.6% | 減碼 |
| Wells Fargo & Company | 65,868 | $42.4 萬 | 0.00% | +40,478+159.4% | 加碼 |
| Susquehanna Fundamental Investments, LLC | 62,544 | $40.2 萬 | 0.01% | −81,726−56.6% | 減碼 |
| Credit Suisse AG | 62,143 | $39.8 萬 | 0.00% | −23,471−27.4% | 減碼 |
| Dynamic Technology Lab Private Ltd | 61,045 | $39.2 萬 | 0.04% | +61,045 | 新進 |
| Simplex Trading, LLC | 58,733 | $37.7 萬 | 0.01% | +58,733 | 新進 |
| State Board of Administration of Florida Retirement System | 53,075 | $34.1 萬 | 0.00% | −160.0% | 減碼 |
| DuPont Capital Management Corp | 52,402 | $33.7 萬 | 0.01% | −20,893−28.5% | 減碼 |
| Deutsche Bank AG | 47,966 | $30.8 萬 | 0.00% | −176,670−78.6% | 減碼 |
| Ensign Peak Advisors, Inc | 43,380 | $27.9 萬 | 0.00% | +43,380 | 新進 |
| Virginia Retirement Systems Et Al | 43,100 | $27.7 萬 | 0.00% | −79,200−64.8% | 減碼 |
| New York State Common Retirement Fund | 42,594 | $27.4 萬 | 0.00% | −166−0.4% | 減碼 |
| Golden State Equity Partners | 41,850 | $26.9 萬 | 0.14% | +11,897+39.7% | 加碼 |
| GFG Capital, LLC | 41,400 | $26.6 萬 | 0.08% | −11,750−22.1% | 減碼 |
| Patriot Financial Group Insurance Agency, LLC | 38,750 | $24.9 萬 | 0.04% | +34,750+868.8% | 加碼 |
| Allspring Global Investments Holdings, LLC | 38,544 | $24.7 萬 | 0.00% | +38,544 | 新進 |
| American International Group, Inc. | 38,262 | $24.6 萬 | 0.00% | −1,144−2.9% | 減碼 |
| Manufacturers Life Insurance Company, The | 38,301 | $24.6 萬 | 0.00% | −872−2.2% | 減碼 |
| Spearhead Capital Advisors, LLC | 34,459 | $22.2 萬 | 0.03% | +801+2.4% | 加碼 |
| Legal & General Group Plc | 31,845 | $20.5 萬 | 0.00% | +1,796+6.0% | 加碼 |
| Invesco Ltd. | 31,568 | $20.3 萬 | 0.00% | −2,589−7.6% | 減碼 |
| Lazard Asset Management LLC | 31,543 | $20.2 萬 | 0.00% | +31,543 | 新進 |
| Royal Bank of Canada | 31,077 | $20.0 萬 | 0.00% | +4,398+16.5% | 加碼 |
| Weiss Multi-Strategy Advisers LLC | 29,883 | $19.2 萬 | 0.00% | −4,216−12.4% | 減碼 |
| Voya Investment Management LLC | 28,866 | $18.6 萬 | 0.00% | −754−2.5% | 減碼 |
| Engineers Gate Manager LP | 28,200 | $18.1 萬 | 0.01% | −32,599−53.6% | 減碼 |
| MetLife Investment Management | 27,007 | $17.4 萬 | 0.00% | +17,452+182.6% | 加碼 |
| ProShare Advisors LLC | 26,371 | $17.0 萬 | 0.00% | +1,026+4.0% | 加碼 |
| Bridgefront Capital, LLC | 24,396 | $15.7 萬 | 0.15% | +3,450+16.5% | 加碼 |
| SG Americas Securities, LLC | 23,716 | $15.2 萬 | 0.00% | −18,483−43.8% | 減碼 |
| Dimensional Fund Advisors LP | 23,570 | $15.2 萬 | 0.00% | 00.0% | 不變 |
| Moors & Cabot, Inc. | 21,550 | $13.9 萬 | 0.01% | +400+1.9% | 加碼 |
| Prelude Capital Management, LLC | 21,000 | $13.5 萬 | 0.01% | 00.0% | 不變 |
| Price T Rowe Associates Inc | 20,412 | $13.1 萬 | 0.00% | −24,500−54.6% | 減碼 |
| North Star Investment Management Corp. | 20,000 | $12.9 萬 | 0.01% | +20,000 | 新進 |
| Tower Research Capital LLC (TRC) | 19,738 | $12.7 萬 | 0.00% | −6,263−24.1% | 減碼 |
| Baird Financial Group, Inc. | 19,817 | $12.7 萬 | 0.00% | +2,137+12.1% | 加碼 |
| Assenagon Asset Management S.A. | 19,366 | $12.5 萬 | 0.00% | +19,366 | 新進 |
| Arizona State Retirement System | 18,288 | $11.8 萬 | 0.00% | +1,924+11.8% | 加碼 |
| First Republic Investment Management, Inc. | 16,684 | $10.7 萬 | 0.00% | −630−3.6% | 減碼 |
| Fox Run Management, L.L.C. | 15,443 | $9.90 萬 | 0.06% | +15,443 | 新進 |
| State of Wyoming | 14,427 | $9.30 萬 | 0.04% | +925+6.9% | 加碼 |
| BNP Paribas Arbitrage, SA | 14,424 | $9.27 萬 | 0.00% | −453,817−96.9% | 減碼 |