Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.13 億；沒有大師持有。
2026 年第 2 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2026/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 96
- 較 2026 年第 1 季 +19 家
- 持有股數
- 2,184 萬
- 較 2026 年第 1 季 +371.4 萬 (+20.5%)
- 總市值
- $2.13 億
- 較 2026 年第 1 季 +$1.11 億 (+108.8%)
- 新進機構
- 33
- 另有 30 家加碼
- 清倉機構
- 14
- 另有 15 家減碼
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.13 億 |
| 2026 年第 1 季 | 77 | $1.02 億 |
| 2025 年第 4 季 | 69 | $7,392 萬 |
| 2025 年第 3 季 | 52 | $1,947 萬 |
| 2025 年第 2 季 | 50 | $1,905 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,152 萬 |
| 2024 年第 3 季 | 91 | $5,076 萬 |
| 2024 年第 2 季 | 114 | $6,014 萬 |
| 2024 年第 1 季 | 114 | $1.17 億 |
| 2023 年第 4 季 | 120 | $6,564 萬 |
| 2023 年第 3 季 | 120 | $1.04 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.41 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.53 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2026 年第 2 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2026 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 1,917,354 | $1,873 萬 | 0.16% | 00.0% | 不變 |
| Adage Capital Partners GP, L.L.C. | 1,521,322 | $1,486 萬 | 0.02% | −285,000−15.8% | 減碼 |
| Acorn Capital Advisors, LLC | 1,518,113 | $1,483 萬 | 4.05% | +1,230,287+427.4% | 加碼 |
| Goldman Sachs Group Inc | 1,424,658 | $1,392 萬 | 0.00% | +477,079+50.3% | 加碼 |
| BlackRock, Inc. | 1,418,799 | $1,386 萬 | 0.00% | +1,173,900+479.3% | 加碼 |
| Kalehua Capital Management LLC | 1,371,288 | $1,340 萬 | 4.27% | +1,371,288 | 新進 |
| Vanguard Capital Management LLC | 958,979 | $936.9 萬 | 0.00% | +219,234+29.6% | 加碼 |
| Catalio Capital Management, LP | 940,855 | $919.2 萬 | 1.73% | +43,146+4.8% | 加碼 |
| Avidity Partners Management LP | 924,487 | $903.2 萬 | 1.45% | −2,995−0.3% | 減碼 |
| T. Rowe Price Investment Management, Inc. | 786,309 | $768.3 萬 | 0.01% | −755,781−49.0% | 減碼 |
| Two Sigma Investments, LP | 695,264 | $679.3 萬 | 0.01% | +544,032+359.7% | 加碼 |
| NEA Management Company, LLC | 576,780 | $563.5 萬 | 0.35% | +576,780 | 新進 |
| Geode Capital Management, LLC | 531,231 | $519.1 萬 | 0.00% | +325,098+157.7% | 加碼 |
| Ghisallo Capital Management LLC | 500,000 | $488.5 萬 | 0.10% | +500,000 | 新進 |
| Soleus Capital Management, L.P. | 440,000 | $429.9 萬 | 0.15% | 00.0% | 不變 |
| UBS Group AG | 353,545 | $345.4 萬 | 0.00% | +159,528+82.2% | 加碼 |
| State Street Corp | 325,991 | $318.5 萬 | 0.00% | +245,249+303.7% | 加碼 |
| Affinity Asset Advisors, LLC | 312,500 | $305.3 萬 | 0.15% | −187,500−37.5% | 減碼 |
| Brevan Howard Capital Management LP | 309,817 | $302.7 萬 | 0.04% | +97,450+45.9% | 加碼 |
| Millennium Management LLC | 305,676 | $298.6 萬 | 0.00% | −114,895−27.3% | 減碼 |
| Boxer Capital Management, LLC | 302,536 | $295.6 萬 | 0.22% | 00.0% | 不變 |
| Davidson Kempner Capital Management LP | 300,000 | $293.1 萬 | 0.05% | 00.0% | 不變 |
| Acadian Asset Management LLC | 298,997 | $291.6 萬 | 0.00% | +50,040+20.1% | 加碼 |
| Silverarc Capital Management, LLC | 297,460 | $290.6 萬 | 0.32% | +297,460 | 新進 |
| Eversept Partners, LP | 276,174 | $269.8 萬 | 0.15% | 00.0% | 不變 |
| JPMorgan Chase & Co | 207,609 | $209.4 萬 | 0.00% | +207,138+43,978.3% | 加碼 |
| Morgan Stanley | 202,506 | $197.8 萬 | 0.00% | +183,936+990.5% | 加碼 |
| Trexquant Investment LP | 188,368 | $184.0 萬 | 0.01% | −69,535−27.0% | 減碼 |
| BNP Paribas Arbitrage, SA | 188,038 | $183.7 萬 | 0.00% | +187,954+223,754.8% | 加碼 |
| Barclays PLC | 165,904 | $162.1 萬 | 0.00% | +158,480+2,134.7% | 加碼 |
| Northern Trust Corp | 160,006 | $156.3 萬 | 0.00% | +121,450+315.0% | 加碼 |
| Vanguard Fiduciary Trust Co | 145,401 | $142.1 萬 | 0.00% | +30,467+26.5% | 加碼 |
| Vanguard Portfolio Management LLC | 134,818 | $131.7 萬 | 0.00% | +134,818 | 新進 |
| Marshall Wace, LLP | 128,451 | $125.5 萬 | 0.00% | 00.0% | 不變 |
| Renaissance Technologies LLC | 108,214 | $105.7 萬 | 0.00% | +2,800+2.7% | 加碼 |
| C WorldWide Group Holding A/S | 100,000 | $97.7 萬 | 0.02% | 00.0% | 不變 |
| Jump Financial, LLC | 94,000 | $91.8 萬 | 0.01% | −168,146−64.1% | 減碼 |
| Invesco Ltd. | 90,304 | $88.2 萬 | 0.00% | +73,566+439.5% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 76,397 | $74.6 萬 | 0.00% | −2,684−3.4% | 減碼 |
| Bridgeway Capital Management, LLC | 71,873 | $70.2 萬 | 0.01% | 00.0% | 不變 |
| J. Goldman & Co LP | 67,500 | $65.9 萬 | 0.02% | +67,500 | 新進 |
| Squarepoint Ops LLC | 63,801 | $62.3 萬 | 0.00% | +63,801 | 新進 |
| Charles Schwab Investment Management Inc | 61,943 | $60.5 萬 | 0.00% | +48,514+361.3% | 加碼 |
| Royal Bank of Canada | 60,430 | $59.0 萬 | 0.00% | +31+0.1% | 加碼 |
| Bank of New York Mellon Corp | 57,262 | $55.9 萬 | 0.00% | +45,863+402.3% | 加碼 |
| Susquehanna Portfolio Strategies, LLC | 54,545 | $53.3 萬 | 0.01% | +29,524+118.0% | 加碼 |
| XTX Topco Ltd | 53,272 | $52.0 萬 | 0.01% | −111,171−67.6% | 減碼 |
| Citadel Advisors LLC | 52,069 | $50.9 萬 | 0.00% | +52,069 | 新進 |
| Bank of America Corp | 49,924 | $48.8 萬 | 0.00% | +30,452+156.4% | 加碼 |
| Birchview Capital, LP | 42,952 | $42.0 萬 | 0.20% | −41,000−48.8% | 減碼 |
| Citigroup Inc | 37,917 | $37.0 萬 | 0.00% | +32,976+667.4% | 加碼 |
| Nuveen, LLC | 37,868 | $37.0 萬 | 0.00% | +37,868 | 新進 |
| Engineers Gate Manager LP | 33,966 | $33.2 萬 | 0.00% | −78,466−69.8% | 減碼 |
| Nomura Asset Management International Inc. | 33,333 | $32.6 萬 | 0.00% | +33,333 | 新進 |
| Jane Street Group, LLC | 33,173 | $32.4 萬 | 0.00% | −72,728−68.7% | 減碼 |
| Toronto Dominion Bank | 30,930 | $30.2 萬 | 0.00% | +30,930 | 新進 |
| Silverback Asset Management LLC | 30,000 | $29.3 萬 | 0.04% | −35,000−53.8% | 減碼 |
| Baird Financial Group, Inc. | 29,791 | $29.1 萬 | 0.00% | 00.0% | 不變 |
| Price T Rowe Associates Inc | 27,225 | $26.6 萬 | 0.00% | +16,339+150.1% | 加碼 |
| ExodusPoint Capital Management, LP | 26,582 | $26.0 萬 | 0.00% | +26,582 | 新進 |
| China Universal Asset Management Co., Ltd. | 25,000 | $24.4 萬 | 0.01% | −5,000−16.7% | 減碼 |
| Simplex Trading, LLC | 24,086 | $23.5 萬 | 0.01% | +24,086 | 新進 |
| Rhumbline Advisers | 23,467 | $22.9 萬 | 0.00% | +23,467 | 新進 |
| Susquehanna Fundamental Investments, LLC | 23,265 | $22.7 萬 | 0.00% | +23,265 | 新進 |
| Velan Capital Investment Management LP | 20,000 | $19.5 萬 | 0.12% | +5,000+33.3% | 加碼 |
| Deutsche Bank AG | 19,425 | $19.0 萬 | 0.00% | +19,425 | 新進 |
| Wells Fargo & Company | 16,903 | $16.5 萬 | 0.00% | +16,903 | 新進 |
| SEI Investments Co | 15,083 | $14.7 萬 | 0.00% | +15,083 | 新進 |
| HSBC Holdings PLC | 13,750 | $13.7 萬 | 0.00% | +2,255+19.6% | 加碼 |
| Headlands Technologies LLC | 12,113 | $11.8 萬 | 0.01% | +12,113 | 新進 |
| MetLife Investment Management | 12,017 | $11.7 萬 | 0.00% | +12,017 | 新進 |
| Virtu Financial LLC | 10,728 | $10.5 萬 | 0.00% | +10,728 | 新進 |
| Y-Intercept (Hong Kong) Ltd | 10,375 | $10.1 萬 | 0.00% | +10,375 | 新進 |
| Quadrature Capital Ltd | 10,296 | $10.1 萬 | 0.00% | +10,296 | 新進 |
| Mirae Asset Global ETFs Holdings Ltd. | 9,171 | $8.96 萬 | 0.00% | +9,171 | 新進 |
| FMR LLC | 8,936 | $8.73 萬 | 0.00% | +8,271+1,243.8% | 加碼 |
| Vanguard Global Advisers, LLC | 8,207 | $8.02 萬 | 0.00% | 00.0% | 不變 |
| Police & Firemen's Retirement System of New Jersey | 5,874 | $5.74 萬 | 0.00% | +5,874 | 新進 |
| New York State Common Retirement Fund | 5,600 | $5.47 萬 | 0.00% | +5,600 | 新進 |
| TD Waterhouse Canada Inc. | 5,707 | $5.45 萬 | 0.00% | +2,504+78.2% | 加碼 |
| Legal & General Group Plc | 1,935 | $1.89 萬 | 0.00% | +1,935 | 新進 |
| Ameritas Investment Partners, Inc. | 1,808 | $1.77 萬 | 0.00% | +1,808 | 新進 |
| Russell Investments Group, Ltd. | 1,592 | $1.56 萬 | 0.00% | +1,592 | 新進 |
| Tower Research Capital LLC (TRC) | 1,259 | $1.23 萬 | 0.00% | +1,259 | 新進 |
| Advisor Group Holdings, Inc. | 402 | $3,927 | 0.00% | 00.0% | 不變 |
| Sterling Capital Management LLC | 352 | $3,439 | 0.00% | +352 | 新進 |
| Harbour Investments, Inc. | 285 | $2,784 | 0.00% | 00.0% | 不變 |
| California State Teachers Retirement System | 274 | $2,677 | 0.00% | +274 | 新進 |
| Quent Capital, LLC | 166 | $1,622 | 0.00% | −69−29.4% | 減碼 |
| MB, Levis & Associates, LLC | 100 | $977 | 0.00% | 00.0% | 不變 |
| SBI Securities Co., Ltd. | 67 | $655 | 0.00% | 00.0% | 不變 |
| Activest Wealth Management | 66 | $645 | 0.00% | 00.0% | 不變 |
| Allworth Financial LP | 26 | $255 | 0.00% | 00.0% | 不變 |
| Caitong International Asset Management Co., Ltd | 14 | $137 | 0.00% | +14 | 新進 |
| West Branch Capital LLC | 3 | $30 | 0.00% | 00.0% | 不變 |
| PlanVest Financial, Inc | 1 | $10 | 0.00% | 00.0% | 不變 |
| Commodore Capital LP | 0 | $0 | 0.00% | −1,950,000−100.0% | 清倉 |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −733,435−100.0% | 清倉 |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −213,810−100.0% | 清倉 |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −191,527−100.0% | 清倉 |