Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.07 億；沒有大師持有。
2026 年第 1 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2026/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 77
- 較 2025 年第 4 季 +11 家
- 持有股數
- 1,767 萬
- 較 2025 年第 4 季 +876.9 萬 (+98.6%)
- 總市值
- $9,840 萬
- 較 2025 年第 4 季 +$3,292 萬 (+50.3%)
- 新進機構
- 25
- 另有 32 家加碼
- 清倉機構
- 14
- 另有 9 家減碼
另有 2 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.07 億 |
| 2026 年第 1 季 | 77 | $9,840 萬 |
| 2025 年第 4 季 | 68 | $6,960 萬 |
| 2025 年第 3 季 | 52 | $1,946 萬 |
| 2025 年第 2 季 | 50 | $1,902 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,120 萬 |
| 2024 年第 3 季 | 91 | $4,922 萬 |
| 2024 年第 2 季 | 114 | $5,863 萬 |
| 2024 年第 1 季 | 114 | $1.13 億 |
| 2023 年第 4 季 | 120 | $6,348 萬 |
| 2023 年第 3 季 | 120 | $1.03 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.40 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.47 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2026 年第 1 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Commodore Capital LP | 1,950,000 | $1,086 萬 | 0.63% | +1,950,000 | 新進 |
| Ra Capital Management, L.P. | 1,917,354 | $1,068 萬 | 0.11% | +1,917,354 | 新進 |
| Adage Capital Partners GP, L.L.C. | 1,806,322 | $1,006 萬 | 0.02% | +1,385,000+328.7% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 1,542,090 | $859.0 萬 | 0.01% | +50,681+3.4% | 加碼 |
| Goldman Sachs Group Inc | 947,579 | $527.8 萬 | 0.00% | +947,579 | 新進 |
| Catalio Capital Management, LP | 897,709 | $500.0 萬 | 1.04% | +754,725+527.8% | 加碼 |
| Vanguard Capital Management LLC | 739,745 | $412.0 萬 | 0.00% | +739,745 | 新進 |
| Ikarian Capital, LLC | 733,435 | $408.5 萬 | 0.58% | +188,881+34.7% | 加碼 |
| Affinity Asset Advisors, LLC | 500,000 | $278.5 萬 | 0.16% | −389,575−43.8% | 減碼 |
| Avidity Partners Management LP | 463,741 | $258.3 萬 | 0.52% | +329,175+244.6% | 加碼 |
| Soleus Capital Management, L.P. | 440,000 | $245.1 萬 | 0.10% | 00.0% | 不變 |
| Millennium Management LLC | 420,571 | $234.3 萬 | 0.00% | +420,571 | 新進 |
| Boxer Capital Management, LLC | 302,536 | $168.5 萬 | 0.22% | +50,000+19.8% | 加碼 |
| Davidson Kempner Capital Management LP | 300,000 | $167.1 萬 | 0.03% | −10,020−3.2% | 減碼 |
| Acorn Capital Advisors, LLC | 287,826 | $160.3 萬 | 0.46% | +287,826 | 新進 |
| Eversept Partners, LP | 276,174 | $153.8 萬 | 0.10% | +276,174 | 新進 |
| Jump Financial, LLC | 262,146 | $146.0 萬 | 0.02% | +208,330+387.1% | 加碼 |
| Trexquant Investment LP | 257,903 | $143.7 萬 | 0.01% | +216,170+518.0% | 加碼 |
| Acadian Asset Management LLC | 248,957 | $138.2 萬 | 0.00% | +245,231+6,581.6% | 加碼 |
| BlackRock, Inc. | 244,899 | $136.4 萬 | 0.00% | −2,659−1.1% | 減碼 |
| Boothbay Fund Management, LLC | 213,810 | $119.1 萬 | 0.03% | +69,182+47.8% | 加碼 |
| Brevan Howard Capital Management LP | 212,367 | $118.3 萬 | 0.01% | +212,367 | 新進 |
| Geode Capital Management, LLC | 206,133 | $114.9 萬 | 0.00% | +18,399+9.8% | 加碼 |
| UBS Group AG | 194,017 | $108.1 萬 | 0.00% | +105,562+119.3% | 加碼 |
| Group One Trading, L.P. | 191,527 | $106.7 萬 | 0.04% | +89,108+87.0% | 加碼 |
| XTX Topco Ltd | 164,443 | $91.6 萬 | 0.02% | +152,539+1,281.4% | 加碼 |
| Two Sigma Investments, LP | 151,232 | $84.2 萬 | 0.00% | +2,439+1.6% | 加碼 |
| ADAR1 Capital Management, LLC | 136,736 | $76.2 萬 | 0.05% | +86,736+173.5% | 加碼 |
| Marshall Wace, LLP | 128,451 | $71.5 萬 | 0.00% | 00.0% | 不變 |
| Vanguard Fiduciary Trust Co | 114,934 | $64.0 萬 | 0.00% | +114,934 | 新進 |
| Engineers Gate Manager LP | 112,432 | $62.6 萬 | 0.01% | +112,432 | 新進 |
| Jane Street Group, LLC | 105,901 | $59.0 萬 | 0.00% | +70,368+198.0% | 加碼 |
| Renaissance Technologies LLC | 105,414 | $58.7 萬 | 0.00% | +45,500+75.9% | 加碼 |
| C WorldWide Group Holding A/S | 100,000 | $55.7 萬 | 0.01% | 00.0% | 不變 |
| Birchview Capital, LP | 83,952 | $46.8 萬 | 0.27% | +83,952 | 新進 |
| State Street Corp | 80,742 | $45.0 萬 | 0.00% | +21,800+37.0% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 79,081 | $44.0 萬 | 0.00% | +21,869+38.2% | 加碼 |
| Bridgeway Capital Management, LLC | 71,873 | $40.0 萬 | 0.01% | +6,000+9.1% | 加碼 |
| Balyasny Asset Management LLC | 70,748 | $39.4 萬 | 0.00% | +70,748 | 新進 |
| Silverback Asset Management LLC | 65,000 | $36.2 萬 | 0.07% | +25,000+62.5% | 加碼 |
| Royal Bank of Canada | 60,399 | $33.6 萬 | 0.00% | +2,399+4.1% | 加碼 |
| Polygon Management Ltd. | 52,984 | $29.5 萬 | 0.06% | +52,984 | 新進 |
| DAFNA Capital Management LLC | 45,800 | $25.5 萬 | 0.06% | −5,200−10.2% | 減碼 |
| Northern Trust Corp | 38,556 | $21.5 萬 | 0.00% | +9,533+32.8% | 加碼 |
| Zimmer Partners, LP | 37,500 | $20.9 萬 | 0.01% | +37,500 | 新進 |
| Centiva Capital, LP | 30,210 | $16.8 萬 | 0.01% | +30,210 | 新進 |
| China Universal Asset Management Co., Ltd. | 30,000 | $16.7 萬 | 0.01% | +30,000 | 新進 |
| Baird Financial Group, Inc. | 29,791 | $16.6 萬 | 0.00% | +1,798+6.4% | 加碼 |
| Susquehanna Portfolio Strategies, LLC | 25,021 | $13.9 萬 | 0.00% | +25,021 | 新進 |
| Susquehanna International Group, LLP | 24,138 | $13.4 萬 | 0.00% | −123,560−83.7% | 減碼 |
| Bank of America Corp | 19,472 | $10.8 萬 | 0.00% | −28,616−59.5% | 減碼 |
| Omers Administration Corp | 19,400 | $10.8 萬 | 0.00% | +19,400 | 新進 |
| Morgan Stanley | 18,570 | $10.3 萬 | 0.00% | +9,712+109.6% | 加碼 |
| Invesco Ltd. | 16,738 | $9.32 萬 | 0.00% | +16,738 | 新進 |
| Velan Capital Investment Management LP | 15,000 | $8.36 萬 | 0.05% | +15,000 | 新進 |
| Charles Schwab Investment Management Inc | 13,429 | $7.48 萬 | 0.00% | +13,429 | 新進 |
| HSBC Holdings PLC | 11,495 | $6.56 萬 | 0.00% | +11,495 | 新進 |
| Bank of New York Mellon Corp | 11,399 | $6.35 萬 | 0.00% | +312+2.8% | 加碼 |
| Price T Rowe Associates Inc | 10,886 | $6.10 萬 | 0.00% | 00.0% | 不變 |
| Vanguard Global Advisers, LLC | 8,207 | $4.57 萬 | 0.00% | +8,207 | 新進 |
| Barclays PLC | 7,424 | $4.14 萬 | 0.00% | +3,315+80.7% | 加碼 |
| Citigroup Inc | 4,941 | $2.75 萬 | 0.00% | +4,940+494,000.0% | 加碼 |
| TD Waterhouse Canada Inc. | 3,203 | $1.86 萬 | 0.00% | 00.0% | 不變 |
| Rockefeller Capital Management L.P. | 733 | $4,083 | 0.00% | 00.0% | 不變 |
| FMR LLC | 665 | $3,704 | 0.00% | −14−2.1% | 減碼 |
| JPMorgan Chase & Co | 471 | $2,496 | 0.00% | −1,270−72.9% | 減碼 |
| Advisor Group Holdings, Inc. | 402 | $2,239 | 0.00% | +120+42.6% | 加碼 |
| Harbour Investments, Inc. | 285 | $1,587 | 0.00% | +200+235.3% | 加碼 |
| Quent Capital, LLC | 235 | $1,309 | 0.00% | 00.0% | 不變 |
| MB, Levis & Associates, LLC | 100 | $557 | 0.00% | 00.0% | 不變 |
| BNP Paribas Arbitrage, SA | 84 | $468 | 0.00% | +2+2.4% | 加碼 |
| SBI Securities Co., Ltd. | 67 | $373 | 0.00% | −7−9.5% | 減碼 |
| Activest Wealth Management | 66 | $368 | 0.00% | 00.0% | 不變 |
| Allworth Financial LP | 26 | $145 | 0.00% | 00.0% | 不變 |
| Advisory Services Network, LLC | 12 | $67 | 0.00% | +12 | 新進 |
| West Branch Capital LLC | 3 | $17 | 0.00% | 00.0% | 不變 |
| PlanVest Financial, Inc | 1 | $6 | 0.00% | +1 | 新進 |
| Opaleye Management Inc. | 0 | $0 | 0.00% | −930,000−100.0% | 清倉 |
| Braidwell LP | 0 | $0 | 0.00% | −303,370−100.0% | 清倉 |
| Exome Asset Management LLC | 0 | $0 | 0.00% | −295,541−100.0% | 清倉 |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −276,881−100.0% | 清倉 |
| Walleye Capital LLC | 0 | $0 | 0.00% | −95,672−100.0% | 清倉 |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −89,729−100.0% | 清倉 |
| Context Capital Management, LLC | 0 | $0 | 0.00% | −62,995−100.0% | 清倉 |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −59,708−100.0% | 清倉 |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −32,868−100.0% | 清倉 |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −31,709−100.0% | 清倉 |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −28,723−100.0% | 清倉 |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −18,316−100.0% | 清倉 |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −12,922−100.0% | 清倉 |
| Aspect Partners, LLC | 0 | $0 | 0.00% | −391−100.0% | 清倉 |
| Vanguard Group Inc | – | – | – | – | 本季未申報 |
| CIBC Private Wealth Group, LLC | – | – | – | – | 本季未申報 |