Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.07 億；沒有大師持有。
2022 年第 4 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2022/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 155
- 較 2022 年第 3 季 +9 家
- 持有股數
- 9,839 萬
- 較 2022 年第 3 季 +3,179 萬 (+47.7%)
- 總市值
- $3.34 億
- 較 2022 年第 3 季 −$2,922 萬 (−8.0%)
- 新進機構
- 32
- 另有 63 家加碼
- 清倉機構
- 23
- 另有 40 家減碼
另有 1 家機構在 2022 年第 3 季持有、還沒有申報 2022 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.07 億 |
| 2026 年第 1 季 | 77 | $9,840 萬 |
| 2025 年第 4 季 | 68 | $6,960 萬 |
| 2025 年第 3 季 | 52 | $1,946 萬 |
| 2025 年第 2 季 | 50 | $1,902 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,120 萬 |
| 2024 年第 3 季 | 91 | $4,922 萬 |
| 2024 年第 2 季 | 114 | $5,863 萬 |
| 2024 年第 1 季 | 114 | $1.13 億 |
| 2023 年第 4 季 | 120 | $6,348 萬 |
| 2023 年第 3 季 | 120 | $1.03 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.40 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.47 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2022 年第 4 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2022 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Avidity Partners Management LP | 9,633,911 | $3,276 萬 | 0.77% | +9,633,911 | 新進 |
| BlackRock Inc. | 8,508,237 | $2,893 萬 | 0.00% | +595,283+7.5% | 加碼 |
| Rubric Capital Management LP | 8,294,621 | $2,820 萬 | 1.23% | +4,304,495+107.9% | 加碼 |
| State Street Corp | 8,287,036 | $2,818 萬 | 0.00% | −723,303−8.0% | 減碼 |
| Palo Alto Investors LP | 5,655,676 | $1,923 萬 | 1.64% | +34,143+0.6% | 加碼 |
| Vanguard Group Inc | 5,197,502 | $1,767 萬 | 0.00% | +384,103+8.0% | 加碼 |
| Armistice Capital, LLC | 3,853,565 | $1,310 萬 | 0.35% | +3,853,565 | 新進 |
| Citadel Advisors LLC | 3,713,153 | $1,230 萬 | 0.01% | +1,903,507+105.2% | 加碼 |
| Jacobs Levy Equity Management, Inc | 2,249,399 | $764.8 萬 | 0.05% | +666,875+42.1% | 加碼 |
| Marshall Wace, LLP | 2,210,223 | $751.5 萬 | 0.02% | +2,051,086+1,288.9% | 加碼 |
| Point72 Asset Management, L.P. | 1,991,613 | $677.1 萬 | 0.03% | +1,988,113+56,803.2% | 加碼 |
| Commodore Capital LP | 1,935,609 | $658.1 萬 | 0.99% | 00.0% | 不變 |
| Iron Triangle Partners LP | 1,926,782 | $655.1 萬 | 1.17% | +1,926,782 | 新進 |
| Nuveen Asset Management, LLC | 1,593,710 | $541.9 萬 | 0.00% | −377,338−19.1% | 減碼 |
| Candriam Luxembourg S.C.A. | 1,535,026 | $521.9 萬 | 0.04% | +200,000+15.0% | 加碼 |
| Bank of America Corp | 1,511,166 | $513.8 萬 | 0.00% | +779,302+106.5% | 加碼 |
| C WorldWide Group Holding A/S | 1,500,000 | $510.0 萬 | 0.07% | 00.0% | 不變 |
| JPMorgan Chase & Co | 1,482,164 | $504.0 萬 | 0.00% | +1,302,937+727.0% | 加碼 |
| Geode Capital Management, LLC | 1,377,128 | $468.2 萬 | 0.00% | +46,693+3.5% | 加碼 |
| Woodline Partners LP | 1,324,884 | $450.5 萬 | 0.06% | −188,375−12.4% | 減碼 |
| Morgan Stanley | 1,289,437 | $438.4 萬 | 0.00% | +209,556+19.4% | 加碼 |
| Opaleye Management Inc. | 1,206,841 | $428.2 萬 | 1.49% | +1,206,841 | 新進 |
| CVI Holdings, LLC | 1,252,408 | $425.8 萬 | 0.54% | +1,252,408 | 新進 |
| ExodusPoint Capital Management, LP | 1,106,132 | $376.1 萬 | 0.06% | +398,852+56.4% | 加碼 |
| Goldman Sachs Group Inc | 1,056,633 | $359.3 萬 | 0.00% | −298,543−22.0% | 減碼 |
| Barclays PLC | 1,046,712 | $355.9 萬 | 0.00% | +591,248+129.8% | 加碼 |
| Ally Bridge Group (NY) LLC | 896,618 | $304.9 萬 | 2.97% | −631,962−41.3% | 減碼 |
| Acadian Asset Management LLC | 845,744 | $287.3 萬 | 0.01% | −4,832−0.6% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 770,713 | $262.0 萬 | 0.01% | +770,713 | 新進 |
| Northern Trust Corp | 745,733 | $253.5 萬 | 0.00% | −8,046−1.1% | 減碼 |
| Two Sigma Advisers, LP | 703,200 | $239.1 萬 | 0.01% | −128,100−15.4% | 減碼 |
| Rafferty Asset Management, LLC | 696,666 | $236.9 萬 | 0.02% | +28,662+4.3% | 加碼 |
| Affinity Asset Advisors, LLC | 661,264 | $224.8 萬 | 1.03% | +661,264 | 新進 |
| Deutsche Bank AG | 594,326 | $202.1 萬 | 0.00% | +509+0.1% | 加碼 |
| Qube Research & Technologies Ltd | 523,788 | $178.1 萬 | 0.01% | +523,788 | 新進 |
| UBS Group AG | 523,259 | $177.9 萬 | 0.00% | +410,713+364.9% | 加碼 |
| Citigroup Inc | 508,593 | $172.9 萬 | 0.00% | −98,803−16.3% | 減碼 |
| Tejara Capital Ltd | 501,562 | $170.5 萬 | 0.99% | +501,562 | 新進 |
| Cubist Systematic Strategies, LLC | 490,010 | $166.6 萬 | 0.01% | +401,646+454.5% | 加碼 |
| Alyeska Investment Group, L.P. | 481,696 | $163.8 萬 | 0.02% | +481,696 | 新進 |
| Monashee Investment Management LLC | 481,696 | $163.8 萬 | 0.70% | +481,696 | 新進 |
| Bank of New York Mellon Corp | 432,881 | $147.2 萬 | 0.00% | +133,890+44.8% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 432,278 | $147.0 萬 | 0.01% | +276,845+178.1% | 加碼 |
| BNP Paribas Arbitrage, SA | 423,620 | $144.0 萬 | 0.00% | −338,900−44.4% | 減碼 |
| Macquarie Group Ltd | 380,000 | $129.2 萬 | 0.00% | −1,465−0.4% | 減碼 |
| Millennium Management LLC | 351,543 | $119.5 萬 | 0.00% | +88,857+33.8% | 加碼 |
| D. E. Shaw & Co., Inc. | 307,959 | $104.7 萬 | 0.00% | +164,153+114.1% | 加碼 |
| Birchview Capital, LP | 291,332 | $99.1 萬 | 0.70% | +22,000+8.2% | 加碼 |
| Two Sigma Investments, LP | 265,308 | $90.2 萬 | 0.00% | +36,973+16.2% | 加碼 |
| Swiss National Bank | 259,150 | $88.1 萬 | 0.00% | +89,700+52.9% | 加碼 |
| Susquehanna International Group, LLP | 255,193 | $86.8 萬 | 0.00% | −136,724−34.9% | 減碼 |
| Putnam Investments LLC | 242,620 | $82.5 萬 | 0.00% | +242,620 | 新進 |
| Wellington Management Group LLP | 228,619 | $77.7 萬 | 0.00% | −16,515−6.7% | 減碼 |
| Charles Schwab Investment Management Inc | 206,831 | $70.3 萬 | 0.00% | +6,330+3.2% | 加碼 |
| DAFNA Capital Management LLC | 192,678 | $65.5 萬 | 0.18% | +192,678 | 新進 |
| Renaissance Technologies LLC | 189,300 | $64.4 萬 | 0.00% | −119,000−38.6% | 減碼 |
| Ameriprise Financial Inc | 164,989 | $56.0 萬 | 0.00% | −5,040−3.0% | 減碼 |
| Walleye Capital LLC | 160,107 | $54.4 萬 | 0.01% | −513,565−76.2% | 減碼 |
| Alliancebernstein L.P. | 158,030 | $53.7 萬 | 0.00% | +19,900+14.4% | 加碼 |
| Russell Investments Group, Ltd. | 146,160 | $49.7 萬 | 0.00% | +16,745+12.9% | 加碼 |
| Hennion & Walsh Asset Management, Inc. | 144,353 | $49.1 萬 | 0.03% | −132,069−47.8% | 減碼 |
| Credit Suisse AG | 141,924 | $48.3 萬 | 0.00% | +2,783+2.0% | 加碼 |
| XTX Topco Ltd | 130,817 | $44.5 萬 | 0.09% | +90,276+222.7% | 加碼 |
| California State Teachers Retirement System | 124,306 | $42.3 萬 | 0.00% | +32,726+35.7% | 加碼 |
| Tudor Investment Corp Et Al | 119,755 | $40.7 萬 | 0.01% | +59,691+99.4% | 加碼 |
| FMR LLC | 110,921 | $37.7 萬 | 0.00% | −1,173−1.0% | 減碼 |
| Los Angeles Capital Management LLC | 101,917 | $34.7 萬 | 0.00% | +23,260+29.6% | 加碼 |
| Rhumbline Advisers | 98,740 | $33.6 萬 | 0.00% | −1,002−1.0% | 減碼 |
| Jane Street Group, LLC | 97,336 | $33.1 萬 | 0.00% | +82,568+559.1% | 加碼 |
| Virginia Retirement Systems Et Al | 91,300 | $31.0 萬 | 0.00% | +70,200+332.7% | 加碼 |
| UBS Asset Management Americas Inc | 82,875 | $28.2 萬 | 0.00% | +10,853+15.1% | 加碼 |
| Algert Global LLC | 82,668 | $28.1 萬 | 0.02% | −13,290−13.8% | 減碼 |
| Gsa Capital Partners LLP | 82,162 | $27.9 萬 | 0.03% | +82,162 | 新進 |
| New York Life Investment Management LLC | 76,968 | $26.2 萬 | 0.00% | +8,675+12.7% | 加碼 |
| Caxton Associates LP | 75,926 | $25.8 萬 | 0.02% | +4,023+5.6% | 加碼 |
| Royal Bank of Canada | 64,229 | $21.8 萬 | 0.00% | +53,054+474.8% | 加碼 |
| AQR Capital Management LLC | 61,647 | $21.0 萬 | 0.00% | −51,029−45.3% | 減碼 |
| Prelude Capital Management, LLC | 58,534 | $19.9 萬 | 0.01% | +45,043+333.9% | 加碼 |
| Jump Financial, LLC | 58,472 | $19.9 萬 | 0.01% | +58,472 | 新進 |
| Price T Rowe Associates Inc | 57,955 | $19.7 萬 | 0.00% | +5,423+10.3% | 加碼 |
| Principal Financial Group Inc | 56,805 | $19.3 萬 | 0.00% | +36,978+186.5% | 加碼 |
| Squarepoint Ops LLC | 52,283 | $17.8 萬 | 0.00% | +52,283 | 新進 |
| Engineers Gate Manager LP | 49,552 | $16.8 萬 | 0.01% | +18,762+60.9% | 加碼 |
| New York State Common Retirement Fund | 49,074 | $16.7 萬 | 0.00% | −18,332−27.2% | 減碼 |
| Point72 Middle East FZE | 47,257 | $16.1 萬 | 0.01% | +47,257 | 新進 |
| Legal & General Group Plc | 45,819 | $15.6 萬 | 0.00% | +8,000+21.2% | 加碼 |
| Martingale Asset Management L P | 45,315 | $15.4 萬 | 0.00% | +45,315 | 新進 |
| Bayesian Capital Management, LP | 43,638 | $14.8 萬 | 0.02% | +43,638 | 新進 |
| Federated Hermes, Inc. | 38,605 | $13.1 萬 | 0.00% | +38,605 | 新進 |
| American International Group, Inc. | 36,828 | $12.5 萬 | 0.00% | +657+1.8% | 加碼 |
| E Fund Management Co., Ltd. | 36,504 | $12.4 萬 | 0.01% | −9,420−20.5% | 減碼 |
| Invesco Ltd. | 36,126 | $12.3 萬 | 0.00% | +1,225+3.5% | 加碼 |
| Redwood Wealth Management Group, LLC | 33,230 | $11.3 萬 | 0.14% | +33,230 | 新進 |
| Occudo Quantitative Strategies LP | 29,817 | $10.1 萬 | 0.01% | +29,817 | 新進 |
| MetLife Investment Management | 29,394 | $9.99 萬 | 0.00% | −12,015−29.0% | 減碼 |
| Voya Investment Management LLC | 28,866 | $9.81 萬 | 0.00% | −142,755−83.2% | 減碼 |
| Fox Run Management, L.L.C. | 28,823 | $9.80 萬 | 0.04% | +28,823 | 新進 |
| Manufacturers Life Insurance Company, The | 28,760 | $9.78 萬 | 0.00% | −260−0.9% | 減碼 |
| Teacher Retirement System of Texas | 28,597 | $9.70 萬 | 0.00% | +5,224+22.4% | 加碼 |
| State Board of Administration of Florida Retirement System | 27,015 | $9.19 萬 | 0.00% | −26,060−49.1% | 減碼 |