Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.07 億；沒有大師持有。
2022 年第 2 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2022/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 150
- 較 2022 年第 1 季 +16 家
- 持有股數
- 6,713 萬
- 較 2022 年第 1 季 −73.8 萬 (−1.1%)
- 總市值
- $3.03 億
- 較 2022 年第 1 季 −$1.96 億 (−39.3%)
- 新進機構
- 28
- 另有 40 家加碼
- 清倉機構
- 12
- 另有 58 家減碼
另有 5 家機構在 2022 年第 1 季持有、還沒有申報 2022 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.07 億 |
| 2026 年第 1 季 | 77 | $9,840 萬 |
| 2025 年第 4 季 | 68 | $6,960 萬 |
| 2025 年第 3 季 | 52 | $1,946 萬 |
| 2025 年第 2 季 | 50 | $1,902 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,120 萬 |
| 2024 年第 3 季 | 91 | $4,922 萬 |
| 2024 年第 2 季 | 114 | $5,863 萬 |
| 2024 年第 1 季 | 114 | $1.13 億 |
| 2023 年第 4 季 | 120 | $6,348 萬 |
| 2023 年第 3 季 | 120 | $1.03 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.40 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.47 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2022 年第 2 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2022 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| State Street Corp | 10,362,009 | $4,673 萬 | 0.00% | −604,692−5.5% | 減碼 |
| BlackRock Inc. | 8,122,849 | $3,664 萬 | 0.00% | +195,231+2.5% | 加碼 |
| Palo Alto Investors LP | 5,621,533 | $2,535 萬 | 2.21% | 00.0% | 不變 |
| Rubric Capital Management LP | 4,400,000 | $1,984 萬 | 1.04% | +792,557+22.0% | 加碼 |
| Vanguard Group Inc | 4,221,980 | $1,904 萬 | 0.00% | +261,272+6.6% | 加碼 |
| Morgan Stanley | 2,386,698 | $1,076 萬 | 0.00% | −425,865−15.1% | 減碼 |
| Commodore Capital LP | 1,935,609 | $873.0 萬 | 1.85% | −1,625,443−45.6% | 減碼 |
| Nuveen Asset Management, LLC | 1,895,378 | $854.8 萬 | 0.00% | +76,330+4.2% | 加碼 |
| Walleye Capital LLC | 1,745,415 | $787.2 萬 | 0.23% | +1,662,337+2,000.9% | 加碼 |
| Jacobs Levy Equity Management, Inc | 1,527,040 | $688.7 萬 | 0.05% | +863,528+130.1% | 加碼 |
| C WorldWide Group Holding A/S | 1,500,000 | $676.5 萬 | 0.08% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 1,446,402 | $652.3 萬 | 0.00% | +547,496+60.9% | 加碼 |
| Geode Capital Management, LLC | 1,326,319 | $598.1 萬 | 0.00% | −11,569−0.9% | 減碼 |
| Rice Hall James & Associates, LLC | 1,315,834 | $593.4 萬 | 0.29% | −29,095−2.2% | 減碼 |
| Candriam Luxembourg S.C.A. | 1,235,724 | $557.2 萬 | 0.05% | −99,302−7.4% | 減碼 |
| Iron Triangle Partners LP | 1,100,000 | $496.1 萬 | 0.80% | −900,000−45.0% | 減碼 |
| Two Sigma Investments, LP | 1,023,752 | $461.7 萬 | 0.02% | −94,173−8.4% | 減碼 |
| Two Sigma Advisers, LP | 986,000 | $444.7 萬 | 0.01% | +210,700+27.2% | 加碼 |
| Northern Trust Corp | 768,098 | $346.3 萬 | 0.00% | +3,763+0.5% | 加碼 |
| Altium Capital Management LP | 700,000 | $315.7 萬 | 1.34% | +55,000+8.5% | 加碼 |
| ExodusPoint Capital Management, LP | 645,985 | $291.3 萬 | 0.04% | +626,498+3,215.0% | 加碼 |
| Frontier Capital Management Co LLC | 632,506 | $285.3 萬 | 0.03% | −646,789−50.6% | 減碼 |
| Millennium Management LLC | 605,383 | $273.0 萬 | 0.00% | −647,490−51.7% | 減碼 |
| Deutsche Bank AG | 594,488 | $268.2 萬 | 0.00% | −4,948−0.8% | 減碼 |
| BNP Paribas Arbitrage, SA | 584,288 | $263.5 萬 | 0.01% | +575,738+6,733.8% | 加碼 |
| Lombard Odier Asset Management (Switzerland) SA | 513,802 | $231.7 萬 | 0.20% | −262,251−33.8% | 減碼 |
| Bank of America Corp | 479,418 | $216.2 萬 | 0.00% | −636,812−57.1% | 減碼 |
| Citigroup Inc | 469,019 | $211.5 萬 | 0.00% | +341,239+267.1% | 加碼 |
| Rafferty Asset Management, LLC | 459,409 | $207.2 萬 | 0.02% | −349,530−43.2% | 減碼 |
| Renaissance Technologies LLC | 454,800 | $205.1 萬 | 0.00% | +239,700+111.4% | 加碼 |
| Citadel Advisors LLC | 408,349 | $184.2 萬 | 0.00% | −446,168−52.2% | 減碼 |
| Voloridge Investment Management, LLC | 389,164 | $175.5 萬 | 0.01% | −287,670−42.5% | 減碼 |
| Macquarie Group Ltd | 382,041 | $172.3 萬 | 0.00% | 00.0% | 不變 |
| UBS Group AG | 317,535 | $143.2 萬 | 0.00% | −200,925−38.8% | 減碼 |
| Hennion & Walsh Asset Management, Inc. | 286,659 | $129.3 萬 | 0.08% | −99,178−25.7% | 減碼 |
| Bank of New York Mellon Corp | 286,381 | $129.1 萬 | 0.00% | −10,519−3.5% | 減碼 |
| Susquehanna International Group, LLP | 281,936 | $127.2 萬 | 0.00% | +807+0.3% | 加碼 |
| Birchview Capital, LP | 269,332 | $121.5 萬 | 0.88% | 00.0% | 不變 |
| HighVista Strategies LLC | 250,377 | $112.9 萬 | 0.68% | +250,377 | 新進 |
| Qube Research & Technologies Ltd | 242,997 | $109.6 萬 | 0.01% | +242,997 | 新進 |
| UBS Oconnor LLC | 227,599 | $102.6 萬 | 0.01% | +227,599 | 新進 |
| Jupiter Asset Management Ltd | 224,603 | $101.1 萬 | 0.01% | +224,603 | 新進 |
| Jane Street Group, LLC | 208,597 | $94.1 萬 | 0.00% | −208,246−50.0% | 減碼 |
| Charles Schwab Investment Management Inc | 199,977 | $90.2 萬 | 0.00% | +5,780+3.0% | 加碼 |
| Wellington Management Group LLP | 196,342 | $88.6 萬 | 0.00% | 00.0% | 不變 |
| Cubist Systematic Strategies, LLC | 190,479 | $85.9 萬 | 0.01% | +28,996+18.0% | 加碼 |
| Acadian Asset Management LLC | 185,296 | $83.6 萬 | 0.00% | −313,626−62.9% | 減碼 |
| JPMorgan Chase & Co | 184,165 | $83.0 萬 | 0.00% | −534,475−74.4% | 減碼 |
| Allianz Asset Management GmbH | 179,225 | $80.8 萬 | 0.00% | +15,240+9.3% | 加碼 |
| Swiss National Bank | 160,750 | $72.5 萬 | 0.00% | 00.0% | 不變 |
| Algert Global LLC | 141,590 | $63.9 萬 | 0.05% | +141,590 | 新進 |
| Credit Suisse AG | 138,696 | $62.6 萬 | 0.00% | +538+0.4% | 加碼 |
| Alliancebernstein L.P. | 118,030 | $53.2 萬 | 0.00% | +2,000+1.7% | 加碼 |
| FMR LLC | 112,517 | $50.7 萬 | 0.00% | −1,455−1.3% | 減碼 |
| Russell Investments Group, Ltd. | 109,095 | $49.1 萬 | 0.00% | +48,349+79.6% | 加碼 |
| Trexquant Investment LP | 96,131 | $43.4 萬 | 0.02% | +67,023+230.3% | 加碼 |
| Rhumbline Advisers | 91,430 | $41.2 萬 | 0.00% | +12,307+15.6% | 加碼 |
| SG Americas Securities, LLC | 91,233 | $41.1 萬 | 0.01% | +91,233 | 新進 |
| California State Teachers Retirement System | 90,482 | $40.8 萬 | 0.00% | +741+0.8% | 加碼 |
| Balyasny Asset Management LLC | 86,059 | $38.8 萬 | 0.00% | −256,425−74.9% | 減碼 |
| Barclays PLC | 81,925 | $36.9 萬 | 0.00% | −5,799−6.6% | 減碼 |
| Dynamic Technology Lab Private Ltd | 78,720 | $35.5 萬 | 0.04% | +78,720 | 新進 |
| State of Wisconsin Investment Board | 72,844 | $32.9 萬 | 0.00% | −22,956−24.0% | 減碼 |
| UBS Asset Management Americas Inc | 71,271 | $32.1 萬 | 0.00% | +9,151+14.7% | 加碼 |
| New York Life Investment Management LLC | 63,275 | $28.5 萬 | 0.00% | +63,275 | 新進 |
| D. E. Shaw & Co., Inc. | 58,500 | $26.4 萬 | 0.00% | +24,387+71.5% | 加碼 |
| Tudor Investment Corp Et Al | 54,513 | $24.6 萬 | 0.01% | +54,513 | 新進 |
| State Board of Administration of Florida Retirement System | 53,075 | $23.9 萬 | 0.00% | 00.0% | 不變 |
| E Fund Management Co., Ltd. | 52,671 | $23.8 萬 | 0.02% | +12,089+29.8% | 加碼 |
| XTX Topco Ltd | 51,606 | $23.3 萬 | 0.10% | +37,177+257.7% | 加碼 |
| Prudential Financial Inc | 51,500 | $23.2 萬 | 0.00% | +51,500 | 新進 |
| Caxton Associates LP | 50,993 | $23.0 萬 | 0.03% | +50,993 | 新進 |
| HRT Financial LP | 49,034 | $22.1 萬 | 0.00% | +49,034 | 新進 |
| Engineers Gate Manager LP | 48,928 | $22.1 萬 | 0.01% | +48,928 | 新進 |
| New York State Common Retirement Fund | 48,874 | $22.0 萬 | 0.00% | −3,551−6.8% | 減碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 45,978 | $20.7 萬 | 0.00% | +45,978 | 新進 |
| Arrowstreet Capital, Limited Partnership | 44,753 | $20.2 萬 | 0.00% | +44,753 | 新進 |
| Ensign Peak Advisors, Inc | 43,380 | $19.6 萬 | 0.00% | 00.0% | 不變 |
| GFG Capital, LLC | 41,400 | $18.7 萬 | 0.06% | 00.0% | 不變 |
| Price T Rowe Associates Inc | 37,670 | $17.0 萬 | 0.00% | +11,372+43.2% | 加碼 |
| DuPont Capital Management Corp | 36,455 | $16.4 萬 | 0.01% | +13,728+60.4% | 加碼 |
| American International Group, Inc. | 35,660 | $16.1 萬 | 0.00% | −85−0.2% | 減碼 |
| Legal & General Group Plc | 33,575 | $15.1 萬 | 0.00% | +1,730+5.4% | 加碼 |
| Invesco Ltd. | 31,095 | $14.1 萬 | 0.00% | −451−1.4% | 減碼 |
| Manufacturers Life Insurance Company, The | 29,827 | $13.5 萬 | 0.00% | +329+1.1% | 加碼 |
| Tower Research Capital LLC (TRC) | 29,096 | $13.1 萬 | 0.00% | +22,576+346.3% | 加碼 |
| Point72 Hong Kong Ltd | 29,111 | $13.1 萬 | 0.01% | +28,640+6,080.7% | 加碼 |
| Voya Investment Management LLC | 28,866 | $13.0 萬 | 0.00% | −1,897−6.2% | 減碼 |
| CSS LLC | 25,728 | $11.6 萬 | 0.01% | +2,300+9.8% | 加碼 |
| Weiss Multi-Strategy Advisers LLC | 25,522 | $11.5 萬 | 0.00% | −2,356−8.5% | 減碼 |
| Allspring Global Investments Holdings, LLC | 25,116 | $11.3 萬 | 0.00% | −23,602−48.4% | 減碼 |
| MetLife Investment Management | 23,213 | $10.5 萬 | 0.00% | −18,559−44.4% | 減碼 |
| Marshall Wace, LLP | 23,000 | $10.3 萬 | 0.00% | +23,000 | 新進 |
| AQR Capital Management LLC | 22,622 | $10.2 萬 | 0.00% | −5,208−18.7% | 減碼 |
| Mirae Asset Global Investments Co., Ltd. | 22,541 | $10.2 萬 | 0.00% | +22,541 | 新進 |
| Moors & Cabot, Inc. | 21,150 | $9.50 萬 | 0.01% | −400−1.9% | 減碼 |
| Principal Financial Group Inc | 20,299 | $9.10 萬 | 0.00% | +7,195+54.9% | 加碼 |
| Man Group plc | – | $8.50 萬 | 0.00% | – | – |
| Los Angeles Capital Management LLC | 18,680 | $8.40 萬 | 0.00% | 00.0% | 不變 |
| Arizona State Retirement System | 18,474 | $8.30 萬 | 0.00% | +95+0.5% | 加碼 |