Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 515
- +21 vs. Q1 2026
- Shares held
- 179.7M
- +7.19M (+4.2%) vs. Q1 2026
- Total value
- $14.3B
- +$1.30B (+10.0%) vs. Q1 2026
- New holders
- 67
- 199 more added
- Sold out
- 46
- 162 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Salomon & Ludwin, LLC | 332 | $26.3K | 0.00% | 00.0% | Unchanged |
| Brown Brothers Harriman & Co | 341 | $27.0K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 370 | $29.3K | 0.00% | 00.0% | Unchanged |
| Golden State Wealth Management, LLC | 376 | $29.8K | 0.00% | 00.0% | Unchanged |
| Cassaday & Co Wealth Management LLC | 400 | $31.7K | 0.00% | 00.0% | Unchanged |
| ORG Wealth Partners, LLC | 400 | $31.7K | 0.00% | 00.0% | Unchanged |
| Mather Group, LLC. | 410 | $32.5K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 516 | $40.9K | 0.00% | −6−1.1% | Reduced |
| Silvant Capital Management LLC | 540 | $42.8K | 0.00% | +540 | New |
| Harbour Investments, Inc. | 558 | $44.3K | 0.00% | +12+2.2% | Added |
| Nisa Investment Advisors, LLC | 580 | $46.0K | 0.00% | +579+57,900.0% | Added |
| Archer Investment Corp | 600 | $47.6K | 0.01% | 00.0% | Unchanged |
| Pacer Advisors, Inc. | 629 | $50.0K | 0.00% | +629 | New |
| Los Angeles Capital Management LLC | 700 | $55.5K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 734 | $58.2K | 0.00% | +53+7.8% | Added |
| EverSource Wealth Advisors, LLC | 858 | $68.0K | 0.00% | −936−52.2% | Reduced |
| Tripletail Wealth Management, LLC | 850 | $69.5K | 0.08% | +850 | New |
| AdvisorNet Financial, Inc | 904 | $71.7K | 0.00% | +331+57.8% | Added |
| IFP Advisors, Inc | 952 | $75.5K | 0.00% | +2+0.2% | Added |
| SRS Capital Advisors, Inc. | 1,004 | $79.6K | 0.00% | +1,004 | New |
| IMA Wealth, Inc. | 1,037 | $82.2K | 0.01% | +1,009+3,603.6% | Added |
| Farther Finance Advisors, LLC | 1,111 | $88.2K | 0.00% | −772−41.0% | Reduced |
| International Assets Investment Management, LLC | 1,232 | $97.6K | 0.01% | +11+0.9% | Added |
| Graticule Asia Macro Advisors LLC | 1,264 | $100.2K | 0.01% | +1,264 | New |
| Sterling Capital Management LLC | 1,289 | $102.2K | 0.00% | −136−9.5% | Reduced |
| Harbor Investment Advisory, LLC | 1,407 | $111.6K | 0.01% | +1,407 | New |
| Smartleaf Asset Management LLC | 1,416 | $114.3K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 1,460 | $115.8K | 0.01% | −95−6.1% | Reduced |
| Parallel Advisors, LLC | 1,684 | $133.5K | 0.00% | −199−10.6% | Reduced |
| Caption Management, LLC | 1,759 | $139.5K | 0.00% | −13,832−88.7% | Reduced |
| Signaturefd, LLC | 1,880 | $149.1K | 0.00% | −198−9.5% | Reduced |
| State of Wyoming | 2,024 | $160.5K | 0.02% | +2,024 | New |
| GAMMA Investing LLC | 2,168 | $171.9K | 0.01% | +402+22.8% | Added |
| Ancora Advisors, LLC | 2,215 | $175.6K | 0.00% | −176−7.4% | Reduced |
| Global Retirement Partners, LLC | 2,282 | $180.9K | 0.00% | +2,282 | New |
| Steward Partners Investment Advisory, LLC | 2,355 | $186.7K | 0.00% | −1,284−35.3% | Reduced |
| Mesirow Financial Investment Management, Inc. | 2,530 | $200.6K | 0.00% | −2,930−53.7% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 2,618 | $207.6K | 0.00% | −75−2.8% | Reduced |
| Kerntke Otto McGlone Wealth Management Group | 2,654 | $210.4K | 0.13% | +2,654 | New |
| IFG Advisory, LLC | 2,678 | $212.3K | 0.01% | +2,678 | New |
| Norden Group LLC | 2,685 | $212.9K | 0.02% | −204−7.1% | Reduced |
| Montis Financial, LLC | 2,700 | $214.1K | 0.04% | 00.0% | Unchanged |
| Voleon Capital Management LP | 2,862 | $226.9K | 0.00% | −20,185−87.6% | Reduced |
| Cambria Investment Management, L.P. | 2,885 | $228.8K | 0.01% | 00.0% | Unchanged |
| University of Texas/Texas Am Investment Managment Co | 2,923 | $231.8K | 0.03% | +2,923 | New |
| Integrated Wealth Concepts LLC | 2,926 | $232.0K | 0.00% | +202+7.4% | Added |
| AlphaGrep UK Ltd | 2,946 | $233.6K | 0.07% | +2,946 | New |
| National Asset Management, Inc. | 2,897 | $233.8K | 0.01% | −48−1.6% | Reduced |
| Larson Financial Group LLC | 3,000 | $237.9K | 0.01% | −31−1.0% | Reduced |
| Argent Trust Co | 3,018 | $239.3K | 0.01% | 00.0% | Unchanged |
| HB Wealth Management, LLC | 3,025 | $239.9K | 0.00% | +99+3.4% | Added |
| Venturi Wealth Management, LLC | 3,061 | $242.7K | 0.01% | 00.0% | Unchanged |
| M&G Plc | 3,090 | $244.1K | 0.00% | −11,333−78.6% | Reduced |
| QRG Capital Management, Inc. | 3,079 | $244.1K | 0.00% | −15−0.5% | Reduced |
| Raab & Moskowitz Asset Management LLC | 3,115 | $247.0K | 0.05% | 00.0% | Unchanged |
| Nwam LLC | 3,238 | $256.7K | 0.01% | 00.0% | Unchanged |
| Mitchell & Pahl Private Wealth, LLC | 3,261 | $258.6K | 0.09% | 00.0% | Unchanged |
| Victrix Investment Advisors | 3,400 | $269.6K | 0.11% | +3,400 | New |
| New York Life Investment Management LLC | 3,458 | $274.2K | 0.00% | +770+28.6% | Added |
| Perigon Wealth Management, LLC | 3,477 | $275.7K | 0.00% | +47+1.4% | Added |
| GF Fund Management Co. Ltd. | 3,497 | $277.3K | 0.00% | −140−3.8% | Reduced |
| Everhart Financial Group, Inc. | 3,503 | $277.8K | 0.02% | +33+1.0% | Added |
| Sequoia Financial Advisors, LLC | 3,567 | $282.8K | 0.00% | +3,567 | New |
| MML Investors Services, LLC | 3,600 | $285.4K | 0.00% | +427+13.5% | Added |
| Crossmark Global Holdings, Inc. | 3,615 | $286.6K | 0.00% | +416+13.0% | Added |
| Berkshire Asset Management LLC | 3,630 | $287.8K | 0.01% | −7−0.2% | Reduced |
| Park Avenue Securities LLC | 3,677 | $292.0K | 0.00% | +3,677 | New |
| Eurizon Capital SGR S.p.A. | 3,639 | $293.9K | 0.00% | +125+3.6% | Added |
| Anb Bank | 3,733 | $296.0K | 0.11% | −36−1.0% | Reduced |
| Bridgefront Capital, LLC | 3,778 | $299.6K | 0.08% | +3,778 | New |
| Pinnacle Wealth Planning Services, Inc. | 3,780 | $299.7K | 0.03% | −433−10.3% | Reduced |
| Rockefeller Capital Management L.P. | 3,832 | $303.8K | 0.00% | −323−7.8% | Reduced |
| Susquehanna International Group, LLP | 3,839 | $304.4K | 0.00% | −8,520−68.9% | Reduced |
| Qsemble Capital Management, LP | 3,887 | $308.2K | 0.04% | −21,871−84.9% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 3,935 | $312.0K | 0.00% | −92,025−95.9% | Reduced |
| Prime Capital Investment Advisors, LLC | 3,938 | $312.2K | 0.00% | −33−0.8% | Reduced |
| Sanctuary Advisors, LLC | 3,938 | $312.2K | 0.00% | +20+0.5% | Added |
| Wealth Enhancement Advisory Services, LLC | 5,394 | $314.2K | 0.00% | +1,269+30.8% | Added |
| HighTower Advisors, LLC | 4,084 | $323.8K | 0.00% | +287+7.6% | Added |
| Prospera Financial Services Inc | 4,194 | $332.5K | 0.00% | −147−3.4% | Reduced |
| Westfield Capital Management Co LP | 4,233 | $335.6K | 0.00% | +731+20.9% | Added |
| Checchi Capital Advisers, LLC | 4,308 | $341.6K | 0.02% | −121−2.7% | Reduced |
| Intrust Bank NA | 4,339 | $344.0K | 0.03% | +283+7.0% | Added |
| Kestra Advisory Services, LLC | 4,384 | $347.6K | 0.00% | +12+0.3% | Added |
| Yorktown Management & Research Co Inc | 4,400 | $348.9K | 0.21% | +4,400 | New |
| Credit Agricole S A | 4,410 | $349.7K | 0.00% | 00.0% | Unchanged |
| Blueshift Asset Management, LLC | 4,433 | $351.5K | 0.08% | +1,656+59.6% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 4,373 | $352.9K | 0.00% | +100+2.3% | Added |
| Gateway Investment Advisers LLC | 4,630 | $367.1K | 0.00% | +4,630 | New |
| Atria Investments LLC | 4,690 | $371.9K | 0.00% | −537−10.3% | Reduced |
| North Dakota State Investment Board | 4,703 | $372.9K | 0.02% | +80+1.7% | Added |
| Azzad Asset Management Inc | 4,784 | $379.3K | 0.03% | +4,784 | New |
| Quantbot Technologies LP | 4,812 | $381.5K | 0.02% | +4,812 | New |
| GWM Advisors LLC | 4,822 | $382.3K | 0.00% | +36+0.8% | Added |
| Wedmont Private Capital | 6,723 | $391.6K | 0.01% | +159+2.4% | Added |
| Vontobel Holding Ltd. | 4,957 | $393.0K | 0.00% | −283−5.4% | Reduced |
| AlphaCore Capital LLC | 4,986 | $395.3K | 0.01% | +2,224+80.5% | Added |
| Moisand Fitzgerald Tamayo, LLC | 5,000 | $396.4K | 0.04% | 00.0% | Unchanged |
| CIBC Asset Management Inc | 5,017 | $397.8K | 0.00% | 00.0% | Unchanged |
| Granite Investment Partners, LLC | 5,026 | $398.5K | 0.02% | −319−6.0% | Reduced |