Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 363
- +21 vs. Q1 2025
- Shares held
- 168.9M
- +2.14M (+1.3%) vs. Q1 2025
- Total value
- $6.67B
- +$1.64B (+32.6%) vs. Q1 2025
- New holders
- 80
- 121 more added
- Sold out
- 59
- 109 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Laurel Wealth Advisors LLC | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Riverview Trust Co | 0 | $0 | 0.00% | −476−100.0% | Sold out |
| Mather Group, LLC. | 0 | $0 | 0.00% | −410−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −381−100.0% | Sold out |
| Oakworth Capital, Inc. | 0 | $0 | 0.00% | −300−100.0% | Sold out |
| Ronald Blue Trust, Inc. | 0 | $0 | 0.00% | −259−100.0% | Sold out |
| Newbridge Financial Services Group, Inc. | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Whittier Trust Co | 0 | $0 | 0.00% | −192−100.0% | Sold out |
| Smartleaf Asset Management LLC | 0 | $0 | 0.00% | −131−100.0% | Sold out |
| Anderson Financial Strategies, LLC | 0 | $0 | 0.00% | −121−100.0% | Sold out |
| First Horizon Advisors, Inc. | 0 | $0 | 0.00% | −112−100.0% | Sold out |
| Picton Mahoney Asset Management | 0 | $0 | 0.00% | −89−100.0% | Sold out |
| Dynamic Wealth Strategies, LLC | 0 | $0 | 0.00% | −80−100.0% | Sold out |
| Blume Capital Management, Inc. | 0 | $0 | 0.00% | −55−100.0% | Sold out |
| Quent Capital, LLC | 0 | $0 | 0.00% | −53−100.0% | Sold out |
| Wolff Wiese Magana LLC | 0 | $0 | 0.00% | −41−100.0% | Sold out |
| Avion Wealth | 0 | $0 | 0.00% | −54−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −28−100.0% | Sold out |
| Bokf, NA | 0 | $0 | 0.00% | −18−100.0% | Sold out |
| Hexagon Capital Partners LLC | 0 | $0 | 0.00% | −9−100.0% | Sold out |
| Umb Bank N A | 0 | $0 | 0.00% | −6−100.0% | Sold out |
| MV Capital Management, Inc. | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| Tanaka Capital Management Inc | – | – | – | – | Not filed |
| Lindbrook Capital, LLC | – | – | – | – | Not filed |