Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 315
- −18 vs. Q4 2022
- Shares held
- 131.1M
- +517.1K (+0.4%) vs. Q4 2022
- Total value
- $4.69B
- −$238.7M (−4.8%) vs. Q4 2022
- New holders
- 34
- 87 more added
- Sold out
- 52
- 128 more reduced
6 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Voya Investment Management LLC | 53,732 | $1.92M | 0.00% | −16,545−23.5% | Reduced |
| Susquehanna International Group, LLP | 55,920 | $2.00M | 0.00% | −1,952−3.4% | Reduced |
| Algert Global LLC | 58,652 | $2.10M | 0.10% | −14,895−20.3% | Reduced |
| Janus Henderson Group PLC | 59,859 | $2.14M | 0.00% | +6,137+11.4% | Added |
| Bokf, NA | 60,261 | $2.15M | 0.05% | +60,261 | New |
| Treasurer of the State of North Carolina | 61,742 | $2.21M | 0.01% | +440+0.7% | Added |
| Guggenheim Capital LLC | 63,563 | $2.27M | 0.02% | +1,404+2.3% | Added |
| Susquehanna Fundamental Investments, LLC | 67,918 | $2.43M | 0.06% | −25,517−27.3% | Reduced |
| LPL Financial LLC | 68,994 | $2.47M | 0.00% | −5,105−6.9% | Reduced |
| Public Employees Retirement System of Ohio | 70,219 | $2.51M | 0.01% | −6,126−8.0% | Reduced |
| Tudor Investment Corp Et Al | 72,577 | $2.59M | 0.05% | +36,212+99.6% | Added |
| Manufacturers Life Insurance Company, The | 72,612 | $2.60M | 0.00% | −9,911−12.0% | Reduced |
| PFS Investments Inc. | 72,776 | $2.71M | 0.05% | +651+0.9% | Added |
| Canada Pension Plan Investment Board | 78,619 | $2.81M | 0.00% | +5,719+7.8% | Added |
| State of New Jersey Common Pension Fund D | 80,433 | $2.87M | 0.01% | 00.0% | Unchanged |
| Davenport & Co LLC | 80,617 | $2.88M | 0.02% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 86,651 | $3.10M | 0.00% | −212,580−71.0% | Reduced |
| Tekla Capital Management LLC | 87,840 | $3.14M | 0.12% | 00.0% | Unchanged |
| Agf Management Ltd | 94,625 | $3.38M | 0.02% | +94,625 | New |
| Point72 Asset Management, L.P. | 95,885 | $3.43M | 0.01% | +95,885 | New |
| Public Sector Pension Investment Board | 98,000 | $3.50M | 0.03% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 99,115 | $3.54M | 0.01% | −92,832−48.4% | Reduced |
| UBS Group AG | 100,946 | $3.61M | 0.00% | −60,525−37.5% | Reduced |
| Alberta Investment Management Corp | 101,426 | $3.62M | 0.04% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 103,476 | $3.70M | 0.01% | −86,822−45.6% | Reduced |
| Jane Street Group, LLC | 103,901 | $3.71M | 0.01% | +92,421+805.1% | Added |
| UBS Oconnor LLC | 107,489 | $3.84M | 0.09% | +107,489 | New |
| Allianz Asset Management GmbH | 108,248 | $3.87M | 0.01% | +5,761+5.6% | Added |
| Eventide Asset Management, LLC | 110,000 | $3.93M | 0.07% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 113,400 | $4.05M | 0.03% | −67,607−37.4% | Reduced |
| State of Wisconsin Investment Board | 115,251 | $4.12M | 0.01% | −12,976−10.1% | Reduced |
| M28 Capital Management LP | 126,300 | $4.51M | 5.10% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 134,000 | $4.79M | 0.01% | −6,500−4.6% | Reduced |
| Twinbeech Capital LP | 136,967 | $4.90M | 0.10% | +136,967 | New |
| Legal & General Group Plc | 140,718 | $5.03M | 0.00% | +13,630+10.7% | Added |
| Sector Gamma AS | 146,441 | $5.23M | 1.27% | +5,068+3.6% | Added |
| BLB&B Advisors, LLC | 148,960 | $5.32M | 0.40% | 00.0% | Unchanged |
| Peregrine Capital Management LLC | 149,247 | $5.33M | 0.15% | +17,536+13.3% | Added |
| Parkman Healthcare Partners LLC | 151,161 | $5.40M | 1.17% | +10,046+7.1% | Added |
| Citadel Advisors LLC | 151,523 | $5.42M | 0.01% | −244,023−61.7% | Reduced |
| Sonora Investment Management Group, LLC | 152,833 | $5.46M | 0.48% | −3,282−2.1% | Reduced |
| State Board of Administration of Florida Retirement System | 155,145 | $5.54M | 0.01% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 165,000 | $5.72M | 0.01% | +12,000+7.8% | Added |
| Tocqueville Asset Management L.P. | 162,480 | $5.81M | 0.11% | +911+0.6% | Added |
| California State Teachers Retirement System | 165,180 | $5.90M | 0.01% | −2,695−1.6% | Reduced |
| Rhumbline Advisers | 176,685 | $6.32M | 0.01% | +11,522+7.0% | Added |
| UBS Asset Management Americas Inc | 176,733 | $6.32M | 0.00% | +937+0.5% | Added |
| Kennedy Capital Management, Inc. | 182,425 | $6.52M | 0.19% | +43,244+31.1% | Added |
| Privium Fund Management B.V. | 182,773 | $6.53M | 2.19% | +33,966+22.8% | Added |
| Citigroup Inc | 184,973 | $6.61M | 0.01% | +55,844+43.2% | Added |
| Tang Capital Management LLC | 200,000 | $7.15M | 1.07% | 00.0% | Unchanged |
| Raymond James & Associates | 200,954 | $7.18M | 0.01% | −24,516−10.9% | Reduced |
| Balyasny Asset Management LLC | 203,466 | $7.27M | 0.02% | +203,466 | New |
| Rafferty Asset Management, LLC | 203,887 | $7.29M | 0.05% | −15,092−6.9% | Reduced |
| Sicart Associates LLC | 210,698 | $7.53M | 2.93% | −35,560−14.4% | Reduced |
| Bank of Montreal | 213,931 | $7.65M | 0.00% | −8,047−3.6% | Reduced |
| Credit Suisse AG | 242,071 | $8.65M | 0.01% | +57,769+31.3% | Added |
| Man Group plc | – | $8.95M | 0.03% | – | – |
| ExodusPoint Capital Management, LP | 265,330 | $9.48M | 0.11% | −39,060−12.8% | Reduced |
| Stifel Financial Corp | 269,831 | $9.64M | 0.01% | +870.0% | Added |
| Nikko Asset Management Americas, Inc. | 297,469 | $9.83M | 0.11% | −39,263−11.7% | Reduced |
| Swiss National Bank | 275,900 | $9.86M | 0.01% | −32,500−10.5% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 278,758 | $9.96M | 0.05% | +48,181+20.9% | Added |
| California Public Employees Retirement System | 282,326 | $10.1M | 0.01% | −47,511−14.4% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 297,469 | $10.6M | 0.01% | −39,263−11.7% | Reduced |
| Eversept Partners, LP | 303,369 | $10.8M | 0.97% | +62,394+25.9% | Added |
| CI Private Wealth, LLC | 305,286 | $10.9M | 0.03% | +2,609+0.9% | Added |
| Hudson Bay Capital Management LP | 305,800 | $10.9M | 0.12% | +80,800+35.9% | Added |
| Nuveen Asset Management, LLC | 313,865 | $11.2M | 0.00% | −9,313−2.9% | Reduced |
| Invesco Ltd. | 315,720 | $11.3M | 0.00% | −6,727−2.1% | Reduced |
| Altrinsic Global Advisors LLC | 322,281 | $11.5M | 0.45% | +3,107+1.0% | Added |
| Baillie Gifford & Co | 332,659 | $11.9M | 0.01% | −1,129−0.3% | Reduced |
| Liontrust Investment Partners LLP | 337,601 | $12.1M | 0.18% | +337,601 | New |
| Two Sigma Advisers, LP | 345,811 | $12.4M | 0.03% | −289,100−45.5% | Reduced |
| Allspring Global Investments Holdings, LLC | 377,211 | $13.5M | 0.02% | −110,852−22.7% | Reduced |
| Nomura Holdings Inc | 401,323 | $14.3M | 0.14% | +1,266+0.3% | Added |
| Candriam Luxembourg S.C.A. | 445,197 | $14.6M | 0.10% | −20,503−4.4% | Reduced |
| Goldman Sachs Group Inc | 422,098 | $15.1M | 0.00% | −500,313−54.2% | Reduced |
| Dimensional Fund Advisors LP | 442,885 | $15.8M | 0.01% | −15,559−3.4% | Reduced |
| Barclays PLC | 458,817 | $16.4M | 0.02% | −48,494−9.6% | Reduced |
| Pinnacle Associates Ltd | 490,655 | $17.5M | 0.36% | −4,095−0.8% | Reduced |
| Royal Bank of Canada | 495,957 | $17.7M | 0.01% | −10,888−2.1% | Reduced |
| AXA S.A. | 520,868 | $18.6M | 0.06% | −702−0.1% | Reduced |
| Jacobs Levy Equity Management, Inc | 536,688 | $19.2M | 0.12% | −153,033−22.2% | Reduced |
| Bank of New York Mellon Corp | 566,095 | $20.2M | 0.00% | −7,703−1.3% | Reduced |
| Wells Fargo & Company | 626,150 | $22.4M | 0.01% | +18,110+3.0% | Added |
| Bank of America Corp | 632,644 | $22.6M | 0.00% | −4,669−0.7% | Reduced |
| Renaissance Technologies LLC | 636,314 | $22.7M | 0.03% | −542,500−46.0% | Reduced |
| Northern Trust Corp | 658,466 | $23.5M | 0.00% | +18,777+2.9% | Added |
| TD Asset Management Inc | 817,308 | $29.2M | 0.04% | +37,813+4.9% | Added |
| Thrivent Financial for Lutherans | 932,540 | $33.3M | 0.08% | +13,208+1.4% | Added |
| Swedbank AB | 961,674 | $34.4M | 0.07% | −59,755−5.9% | Reduced |
| Morgan Stanley | 1,003,009 | $35.8M | 0.00% | +66,300+7.1% | Added |
| JPMorgan Chase & Co | 1,057,395 | $37.8M | 0.00% | +87,085+9.0% | Added |
| Pictet Asset Management SA | 1,113,042 | $39.8M | 0.05% | +739,456+197.9% | Added |
| Norges Bank | 1,132,691 | $40.5M | 0.01% | −163,956−12.6% | Reduced |
| Charles Schwab Investment Management Inc | 1,186,393 | $42.4M | 0.01% | −69,875−5.6% | Reduced |
| Macquarie Group Ltd | 1,493,903 | $53.4M | 0.06% | +2,216+0.1% | Added |
| First Trust Advisors LP | 1,638,943 | $58.6M | 0.07% | −141,990−8.0% | Reduced |
| Camber Capital Management LP | 1,925,000 | $68.8M | 2.35% | 00.0% | Unchanged |