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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 3 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

Q1 2023 vs. Q4 2022

How the institutions holding Ionis Pharmaceuticals Inc changed between Q4 2022 and Q1 2023.

All holders in Q1 2023All holders in Q4 2022

13F holders of IONS: Q4 2022 compared with Q1 2023
MeasureQ4 2022Of which not filed for Q1 2023Q1 2023Change
Holders3396315−18
Shares130.6M17.9K131.1M+517.1K (+0.4%)
Value$4.93B$700.8K$4.69B−$238.7M (−4.8%)

6 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so the changes leave them out.

New holders (34)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q1 2023 but not at the end of Q4 2022.

Institutions new to IONS in Q1 2023
InstitutionSharesValue% of portfolio
Liontrust Investment Partners LLP337,601$12.1M0.18%
Balyasny Asset Management LLC203,466$7.27M0.02%
Twinbeech Capital LP136,967$4.90M0.10%
UBS Oconnor LLC107,489$3.84M0.09%
Point72 Asset Management, L.P.95,885$3.43M0.01%
Agf Management Ltd94,625$3.38M0.02%
Bokf, NA60,261$2.15M0.05%
International Biotechnology Trust PLC43,000$1.54M0.43%
Estate Counselors, LLC33,110$1.18M0.16%
Massachusetts Financial Services Co27,153$970.4K0.00%
Bayesian Capital Management, LP21,227$758.7K0.09%
Mirae Asset Global Investments Co., Ltd.15,571$556.5K0.00%
Inceptionr LLC12,790$457.1K0.15%
Sawtooth Solutions, LLC12,247$437.7K0.01%
Capital Fund Management S.A.11,314$404.4K0.01%
Gsa Capital Partners LLP9,422$337.0K0.03%
Bridgefront Capital, LLC7,056$252.2K0.15%
HSBC Holdings PLC6,623$234.2K0.00%
Kapitalo Investimentos Ltda3,381$120.8K0.04%
Icon Wealth Partners, LLC3,073$109.8K0.01%
Acadian Asset Management LLC3,073$109.0K0.00%
Values First Advisors, Inc.1,594$57.0K0.04%
Horizon Investments, LLC1,339$47.9K0.00%
Strategic Investment Solutions, Inc.500$17.9K0.00%
Ameritas Advisory Services, LLC191$6.83K0.00%
Salem Investment Counselors Inc123$4.40K0.00%
GPS Wealth Strategies Group, LLC119$4.25K0.00%
Abound Wealth Management67$2.40K0.00%
Jackson, Grant Investment Advisers, Inc.40$1.43K0.00%
CVA Family Office, LLC30$1.07K0.00%
Central Bank & Trust Co28$1.00K0.00%
Front Row Advisors LLC20$1.00K0.00%
Cape Investment Advisory, Inc.13$4650.00%
Quilter Plc363––

Sold out (52)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q4 2022 and filed for Q1 2023 without it.

Institutions that sold out of IONS in Q1 2023
InstitutionShares, Q4 2022Value, Q4 2022
Qube Research & Technologies Ltd330,724$12.5M
Redmile Group, LLC266,187$10.1M
Jefferies Financial Group Inc.197,009$7.44M
Natixis159,678$6.03M
Cubist Systematic Strategies, LLC128,070$4.84M
Healthcare of Ontario Pension Plan Trust Fund63,000$2.38M
National Bank of Canada60,895$2.30M
Duality Advisers, LP53,524$2.02M
Gateway Investment Advisers LLC51,174$1.93M
Intech Investment Management LLC50,510$1.91M
Rhenman & Partners Asset Management AB50,000$1.89M
Voloridge Investment Management, LLC30,709$1.16M
Toronto Dominion Bank30,706$1.16M
Edgestream Partners, L.P.27,393$1.03M
Pinebridge Investments, L.P.26,959$1.02M
STRS Ohio25,791$974.0K
Dynamic Technology Lab Private Ltd25,580$966.0K
Cantor Fitzgerald, L. P.22,880$864.0K
Kestra Advisory Services, LLC22,413$846.5K
Echo Street Capital Management LLC19,103$721.5K
American Trust15,970$603.2K
Group One Trading, L.P.15,463$584.0K
Quantedge Capital Pte Ltd15,100$570.3K
Campbell & CO Investment Adviser LLC15,018$567.2K
Teza Capital Management LLC12,624$476.8K
Hanseatic Management Services Inc10,811$408.0K
Verition Fund Management LLC10,512$397.0K
Grantham, Mayo, Van Otterloo & Co. LLC9,700$366.4K
ETF Managers Group, LLC7,649$288.9K
AQR Capital Management LLC7,569$282.0K
Calamos Advisors LLC7,026$265.4K
Sherbrooke Park Advisers LLC7,000$264.4K
Oversea-Chinese Banking CORP Ltd6,840$258.0K
Stonegate Investment Group, LLC6,807$257.1K
MQS Management LLC6,547$247.3K
Seven Eight Capital, LP5,990$226.2K
Cetera Advisor Networks LLC5,672$214.2K
Regions Financial Corp5,346$202.0K
Sectoral Asset Management Inc4,450$168.1K
Aquatic Capital Management LLC3,200$121.0K
Chiron Investment Management, LLC3,173$119.8K
Rockefeller Capital Management L.P.2,581$97.0K
Walleye Trading LLC1,316$49.7K
Romano Brothers and Company1,148$43.4K
Altshuler Shaham Ltd695$26.3K
Zullo Investment Group, Inc.682$25.8K
Insight Financial Services200$7.55K
Hall Laurie J Trustee115$4.00K
Affiance Financial, LLC100$3.78K
Capital Advisors, Ltd. LLC63$2.00K
Concord Wealth Partners36$1.36K
Hexagon Capital Partners LLC9$340

Not filed for Q1 2023 yet (6)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q4 2022 and haven't filed a 13F for Q1 2023. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding IONS in Q4 2022 that haven't filed for Q1 2023
InstitutionShares, Q4 2022Value, Q4 2022
Comerica Bank11,522$459.0K
Alpha Paradigm Partners, LLC5,335$202.0K
Heritage Wealth Management, LLC900$34.0K
Semmax Financial Advisors Inc.84$3.00K
Cornerstone Planning Group LLC45$1.83K
CoreCap Advisors, LLC26$982